Global, regional, and national burden of early-onset colorectal cancer from 1990 to 2021: a systematic analysis based on the global burden of disease study 2021 by Yang Meng, Zongbiao Tan, Junhai Zhen, Di Xiao, Liwei Cai, Weiguo Dong, Changzheng Chen

“…Abstract Background To provide estimates and trends for burdens of early-onset colorectal cancer (EOCRC) from 1990 to 2021 at the global, regional, and national levels, and to provide projections of EOCRC burden through 2030. Methods A trend analysis based on the Global Burden of Diseases 2021. …”
Get full text

Current Trends in Mortality Attributable to Racial or Ethnic Disparities in Post-Surgical Population in The United States: A Population-Based Study by Christian Mpody, MD, PhD, MPH, MBA, Ana F. Best, PhD, Clara N. Lee, MD, MPP, David L. Stahl, MD, Vidya T. Raman, MD, MBA, Richard D. Urman, MD, MBA, Joseph D. Tobias, MD, Olubukola O. Nafiu, MD, FRCA, MS

“…To eliminate the disparity between Black and White patients by 2030, we need a 2.7% annualized reduction in the projected mortality among Black patients. For Hispanics, the annualized reduction needed is 0.8%. …”
Get full text

Salivary proteomics profiling reveals potential biomarkers for chronic kidney disease: a pilot study by Bianca Uliana Picolo, Nathália Rabello Silva, Mário Machado Martins, Hebréia Oliveira Almeida-Souza, Letícia Cristina Machado de Sousa, Richard Costa Polveiro, Luiz Ricardo Goulart Filho, Robinson Sabino-Silva, Vivian Alonso-Goulart, Luciana Saraiva da Silva

“…Multivariate analysis was performed to generate the orthogonal partial least squares discriminant analysis (OPLS-DA) model and the variable importance in projection (VIP) scores. The accuracy of candidate biomarker proteins was evaluated using receiver operating characteristic (ROC) curves.ResultsIn total, 431 proteins were identified in the salivary proteomic profile, and 3 proteins were significantly different between the groups: apoptosis inhibitor 5 (API5), phosphoinositide phospholipase C (PI-PLC), and small G protein signaling modulator 2 (Sgsm2). …”
Get full text

Completion of the Central Italy daily precipitation instrumental data series from 1951 to 2019 by Gamal AbdElNasser Allam Abouzied, Guoqiang Tang, Simon Michael Papalexiou, Martyn P. Clark, Eleonora Aruffo, Piero Di Carlo

“…It is also an essential meteorological variable used as input for hydroclimatic models and projections. However, precipitation data frequently lack complete series, especially at daily and sub‐daily precipitation stations, which are usually large, bulky, and complex. …”
Get full text

Discrimination of Selected Cold-Pressed and Refined Oils by Untargeted Profiling of Phase Transition Curves of Differential Scanning Calorimetry by Mahbuba Islam, Montowska Magdalena, Fornal Emilia, Tomaszewska-Gras Jolanta

“…Variables influence on projection (VIP) plot indicated the most significant variables of the heat flow values detected at temperatures around −29°C, −32°C, −14°C, −10°C, −24°C and −41°C for the differentiation of oils. …”
Get full text

SEAHORS: Spatial Exploration of ArcHaeological Objects in R Shiny by Royer, Aurélien, Discamps, Emmanuel, Plutniak, Sébastien, Thomas, Marc

“…SEAHORS can generate five types of plots: 3D, 2D and density plots, as well as 2D plots by slices (i.e. subdivisions according to a third dimension) and 2D plots with a modification of the angle of projection (i.e. to explore spatial organization without the constraints of the field grid orientation). …”
Get full text

Constraints on triggered seismicity and its control on permeability evolution by Derek Elsworth, Ziyan Li, Pengliang Yu, Mengke An, Fengshou Zhang, Rui Huang, Zihan Sun, Guanglei Cui, Tianyu Chen, Quan Gan, Yixin Zhao, Jishan Liu, Shimin Liu

“…Although high-fidelity data sets are scarce, the EGS-Collab and Utah FORGE hydraulic stimulation field demonstration projects provide high-fidelity data sets that concurrently track permeability evolution and triggered seismicity. …”
Get full text

Deep unsupervised clustering for prostate auto-segmentation with and without hydrogel spacer by Hengrui Zhao, Biling Wang, Michael Dohopolski, Ti Bai, Steve Jiang, Dan Nguyen

“…We then used Uniform Manifold Approximation and Projection (UMAP) for dimensionality reduction and employed k-means clustering to assign each patient to a cluster. …”
Get full text

Macroecological predictors to determine future refuges of Luciobarbus species in the Tigris–Euphrates basin: Rethinking conservation strategies and management by Hadi Khoshnamvand, Seyed Mohsen Mousavi, Asef Darvishi, Kourosh Ahmadi, Amir Naghibi, Karel Janko, Asghar Abdoli, Faraham Ahmadzadeh

“…We employed a generalized linear model (GLM) with a quasi-Poisson distribution to create a map depicting the richness of Luciobarbus fish species.Our projections indicate that suitable habitats will decline in both time series under climate change SSP126 and SSP585 scenarios, resulting in the loss of certain habitat patches in the Southwest of Iran, Syria and Iraq. …”
Get full text

Equalizer Design: HBOA-DE-trained radial basis function neural networks by Santosh Kumar Das, Satya Ranjan Pattanaik, Pradyumna Kumar Mohapatra, Saroja Kumar Rout, Abdulaziz S. Almazyad, Muhammed Basheer Jasser, Guojiang Xiong, Ali Wagdy Mohamed

“…It has been shown that the projected method outclasses other methods even in poor signal-to-noise ratio conditions, which is borne out by extensive simulation studies.…”
Get full text

Investigation of Coolant Local Hydrodynamics in the Mixed Core of the VVER Reactor by S. M. Dmitriev, A. V. Gerasimov, A. A. Dobrov, D. V. Doronkov, A. N. Pronin, A. V. Ryazanov, D. N. Solntsev, A. E. Khrobostov

“…In the framework of this study the analysis of the spatial distribution of the projections of the velocity of the coolant flow was fulfilled that has made it possible to pinpoint regularities that are intrinsic to the coolant flowing around spacing, mixing and combined spacing grates of the TVSA. …”
Get full text

Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome by Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng

“…Results EA significantly alleviated neuroendocrine dysfunction in PCOS-like mice by restoring the density and coverage of GnRH axonal projections. MA displayed similar therapeutic effects but had less pronounced effects on GnRH axons. …”
Get full text

Transcriptional signature of CD56bright NK cells predicts favourable prognosis in bladder cancer by Md Abdullah Al Kamran Khan, Alexander James Sedgwick, Yuhan Sun, Julian P. Vivian, Julian P. Vivian, Julian P. Vivian, Alexandra J. Corbett, Riccardo Dolcetti, Riccardo Dolcetti, Riccardo Dolcetti, Theo Mantamadiotis, Theo Mantamadiotis, Stefano Mangiola, Stefano Mangiola, Stefano Mangiola, Alexander David Barrow

“…A similar favorable survival trend was projected using gene signatures for mature myeloid dendritic cells (mDC) and CD8+ effector memory T cells (TEM) and unveiled a potential CD56bright NK-mDC-CD8+T cell crosstalk in the BLCA tumour microenvironment. …”
Get full text

Filamented hydrogels as tunable conduits for guiding neurite outgrowth by Hao Liu, Anna Puiggalí-Jou, Parth Chansoria, Jakub Janiak, Marcy Zenobi-Wong

“…Matrix stiffness was fine-tuned by varying the projection light dose, yielding matrices with stiffness ranging from 0.6 to 5.7 kPa. …”
Get full text

Detection of the Effect of Climate Change on the Mechanism of Heat Islands in Tehran Province by Niloofar Mohammadi, Zahra Hejazizadeh, Parviz Zeaiean Firouzabadi, Alireza Karbalaee

“…Examining the trend of the temperature time series with Mann-Kendall test of all stations showed an increasing trend, in the exam of the rainfall time series of the stations (Abali, Shemiran and Mehrabad) in the months of October and November, it was accompanied by sudden changes and jumps, which due to the increase in extreme events It is justifiable. in the HadGEM3 model according to the SSP5 scenario; The temperature forecast of Mehrabad station during the period (2060 to 2021) has shown the highest temperature compared to the base period in July with a 5% increase; And the most rainy period is projected to early autumn and winter in the period (2021-2060). …”
Get full text

Prediction of Potential Habitat Distributions and Climate Change Impacts on the Rare Species <i>Woonyoungia septentrionalis</i> (Magnoliaceae) in China Based on MaxEnt by Weihao Yao, Zenghui Wang, Yu Fan, Danyang Liu, Zeyang Ding, Yumei Zhou, Shuyue Hu, Wei Zhang, Jing Ou

“…Under future climate scenarios, suitable habitats for <i>Woonyoungia septentrionalis</i> are projected to shrink and shift toward higher altitudes and latitudes, increasing the risk of extinction due to the “mountain trap” effect, where migration is constrained by limited habitat at higher elevations. …”
Get full text

Study on Seismic Dynamic Response of Deep-Buried Tunnel Based on Tectonic Stress by Junjie He, Song Hu, Yonggang Guo

“…It is hoped that the contents of the study will contribute to the prevention and control of seismic geological hazards in the tunnel-engineering region and render technical support for the design and construction of similar projects in this region.…”
Get full text

Greenhouse gas offsets distort the effect of clean energy tax credits in the United States by Emily Grubert, Wilson Ricks, Danny Cullenward

“…Prominent clean energy tax credits in the United States (U.S.) could drive large expenditures that materially increase greenhouse gas (GHG) emissions if their implementing regulations assign negative values to avoided GHG emissions and allow projects to offset other supply chain emissions on this basis. …”
Get full text

Contradictions of students’ motivation for participation in the activities of voluntary organisations by A. V. Starshinova

“…The quantitative research strategy included such tools as drawing up a portrait of a volunteer based on projective questions, using the method of unfinished sentences, the method of direct ranking of motives. …”
Get full text

Determining Priority Areas for the Technological Development of Oil Companies in Mexico by Tatyana Semenova, Juan Yair Martínez Santoyo

“…The dynamics of patent generation are an important factor in assessing the technological component and, in general, the effectiveness of projects in the energy sector.…”
Get full text