The pattern of antibiotic utilisation among intensive care unit patients hospitalised in a Gauteng (South African) provincial tertiary hospital: Comparing findings before and durin... by L Spinickum, Z Booth, S Leigh-de Rapper

“…Various mechanisms may contribute to and direct the progression of antibiotic resistance. A prominent driver associated with antibiotic resistance is inappropriate use or consumption. …”
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Serum and plasma as a good candidates of body fluids for detection lung cancer by FTIR liquid biopsy by Jolanta Smok-Kalwat, Stanisław Góźdź, Paweł Macek, Zuzanna Kalwat, Maryna Khalavka, Wioletta Rzad, Andrzej Stepulak, Joanna Depciuch

“…Abstract Using Fourier Transform Infrared spectroscopy (FTIR), it is possible to show chemical composition of materials and / or profile chemical changes occurring in tissues, cells, and body fluids during onset and progression of diseases. For diagnostic application, the use of blood would be the most appropriate in biospectroscopy studies since, (i) it is easily accessible and, (ii) enables frequent analyses of biochemical changes occurring in pathological states. …”
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Bibliometric analysis of glycolysis and prostate cancer research from 2004 to 2024 by Congxu Zhu, Jingjing Yang, Lumei Liu, Bonan Li, Tiansong Sun, Wen Sheng, Qinghu He

“…Enhanced glycolysis and excessive lactate secretion are recognized as critical factors driving the progression of various cancers. This study systematically investigated the research trends associated with glycolysis in PCa through bibliometric analysis. …”
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Vasoreactive testing prevalence and characteristics in patients with idiopathic pulmonary arterial hypertension by Goncharova Natalia, Kirill Lapshin, Aelita Berezina, Irina Zlobina, Anton Ryzhkov, Zhaneta Matakaeva, Elizaveta Andreeva, Olga Moiseeva

“…CPET should be used more widely to detect the early signs of PAH progression in low risk or VRT + patients.…”
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Risdiplam utilization, adherence, and associated health care costs for patients with spinal muscular atrophy: a United States retrospective claims database analysis by Anish Patel, Walter Toro, Min Yang, Wei Song, Raj Desai, Mingchen Ye, Nadia Tabatabaeepour, Omar Dabbous

“…Abstract Background Spinal muscular atrophy (SMA) is a genetic neuromuscular disease associated with progressive loss of motor function. Risdiplam, a daily oral therapy, was approved in the United States for the treatment of SMA. …”
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Could Infectious Agents Play a Role in the Onset of Age-related Macular Degeneration? A Scoping Review by Petra P. Larsen, MD, PhD, Virginie Dinet, PhD, Cécile Delcourt, PhD, Catherine Helmer, MD, PhD, Morgane Linard, MD, PhD

“…Clarifying whether certain infections participate in its onset or progression seems essential, given the potential implications for treatment and prevention. …”
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Permeability Characteristics of Combined Coal with Different Water Contents by Hongyu Pan, Yao Zhang, Lei Zhang, Yan Cao, Yuhang Chu, Shihua Yang

“…Seepage velocity consistently decreased with increasing water content across all osmotic pressure levels, although the rate of decline progressively weakened. The maximum permeability difference between the forward and reverse samples was 10.48 × 10⁻¹³ m². …”
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Burden of Anemia among Human Immunodeficiency Virus-Positive Adults on Highly Active Antiretroviral Therapy at Hawassa University Compressive Specialized Hospital, Hawassa, Ethiopi... by Sisay Tesfaye, Melaku Hirigo, Dawit Jember, Mekdes Shifeta, Worku Ketema

“…It has a considerable impact on the progression of HIV to advanced stages. This study aimed at assessing the burden of anemia in adult HIV-infected patients who are on highly active antiretroviral therapy (HAART) and have follow-up at Hawassa University Comprehensive Specialized Hospital (HUCSH) Antiretroviral therapy (ART) clinic. …”
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Malignant transformation of proliferative Verrucous Leukoplakia—systematic review & meta-analysis by Khadijah Mohideen, Snehashish Ghosh, Chandrasekaran Krithika, Mutaz Ali-Hassan, Revant Chole, Safal Dhungel

“…Aim The present systematic review explores the demographic characteristics, risk factors, progression patterns, treatment preferences, and outcomes for PVL lesions that undergo malignant transformation. …”
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Association of hepatitis B virus DNA levels with efficacy and safety and the impact of antiviral therapy on prognosis in liver cancer patients receiving immune checkpoint inhibitor... by Hongxia Cui, Su Li, Wu Lv, Jing Xiang

“…The outcomes were hazard ratios (HRs) for overall survival (OS) and progression-free survival (PFS), as well as odds ratios (ORs) for objective response rate (ORR), disease control rate (DCR) and HBV reactivation (HBVr). …”
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SDG11-Based Sustainability Assessment of Urban Communities: A Case Study of Changsha by Qin Shuqian, Zhang Nan, Zhu Peijuan, Zhang Yong, Zhang Chen

“…It is found that: (1) During the period 2010-2020, the degree of achievement of community SDG in Changsha falls in the "relative closeness" range, with a "core-periphery" spatial distribution from the high sections to the low ones. (2) Of the 7 goals, housing guarantee, disaster prevention and relief, and environmental governance are progressing well; public transportation and heritage protection are improving significantly; public space is rising slowly; however, planning management is less than ideal. (3) Based on the assessment results of the coupling coordination degree of the communities' economic-social-environmental systems, the sample communities are classified into three types: coordinated development, transitional development, and dysfunctional decline communities. …”
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Effects of photobiomodulation combined with rehabilitation exercise on pain, physical function, and radiographic changes in mild to moderate knee osteoarthritis: A randomized contr... by Yan Ling Tay, Mohd Azzuan Ahmad, Nor Hamdan Mohamad Yahaya, Devinder Kaur Ajit Singh

“…The potential for H-PBMT to offer sustained benefits and modify the underlying progression of KOA remains insufficiently explored, warranting further investigation.…”
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Correlation between METTL3 overexpression and 18F-FDG uptake in patients with soft tissue sarcoma by Tong Wu, Jinghui Xie, Hongbo Feng, Hua Zhang, Juan Tao, Bo Chen

“…Abstract Background N6-methyladenosine (m6A) methylation plays a key role in tumor progression. However, the significance of methyltransferase-like 3 (METTL3) in biological processes of soft tissue sarcoma (STS) patients, and the relationship between METTL3 and STS are unclear. …”
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Isolation and Characterization of Coronavirus and Rotavirus Associated with Calves in Central Part of Oromia, Ethiopia by Umer Seid, Fufa Dawo, Asamino Tesfaye, Munera Ahmednur

“…After 3 subsequent passages, progressive cytopathic effect (CPE), i.e., rounding, detachment, and the destruction of monolayer cell of five samples (1 sample of coronavirus and 4 samples of rotavirus) (71.4%) were observed. …”
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Different expression of circulating microRNA profile in tibetan OSAHS with metabolic syndrome patients by Xue-feng Shi, Xiang He, Ze-rui Sun, Jie Duo, Hao Yang

“…In addition, GO enrichment analysis of target genes associated with differentially expressed miRNAs revealed significant enrichment in metabolic processes, suggesting that the differential expression of OSAHS-induced miRNAs may contribute to the progression of metabolic disorders through the regulation of metabolic pathways. …”
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The financial character of policing in Tunisia: collusions, extraversion and the criminalization of informality by Daniela Musina

“…This process is accelerated by the progressive conflation of informal money circulation channels with mobility and migrant transit, and of money couriers (passeurs de fonds) with smugglers.…”
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Smoking habits, awareness and support needs for cessation among people with multiple sclerosis in Australia: findings from an online survey by Roshan das Nair, Ron Borland, Claudia H Marck, Isabelle Weld-Blundell, Lisa Grech, Sarah L White

“…Awareness of the harms of smoking on MS onset (n=68, 24.3%) and progression (n=116, 41.6%) was low. Almost a quarter (n=67, 23.8%) of participants were regularly exposed to passive smoke, and awareness of associated harm was also low (n=47, 16.8%). …”
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First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies by Peter Ellmark, Jeffrey Yachnin, Ana Carneiro, Lena Schultz, Amanda Hahn, Sumeet Ambarkhane, Karin Enell Smith, Gustav J. Ullenhag

“…Escalating doses were given until disease progression, unacceptable toxicity, or withdrawal of consent. …”
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Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients by Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif

“…It has been involved in progression, growth, epithelial mesenchymal transition and metastasis of hepatocellular carcinoma (HCC). …”
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The Validation of a Novel, Sex-Specific LDL-Cholesterol Equation and the Friedewald, Sampson-NIH, and Extended-Martin–Hopkins Equations Against Direct Measurement in Korean Adults... by Hyun Suk Yang, Soo-Nyung Kim, Seungho Lee, Mina Hur

“…In the TG ≥ 400 mg/dL group, the MAPE increased progressively: SSLE (10.2%), ext-Martin–Hopkins (12.0%), Sampson-NIH (12.7%), and Friedewald (27.4%). …”
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