A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights by Ridwan S, Harsono AB, Suardi D, Kurniadi A, Mantilidewi KI, Hidayat YM

“…Herein, we present a rare case of double-primer ovarian and thyroid cancer, which is a clear cell ovarian carcinoma metachronous with papillary thyroid carcinoma.Case Report: A 47-year-old nulliparous woman presented to our Gynecology Oncology facility with an abdominal mass that had progressively increased in size over the last three months. …”
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A COMPARATIVE STUDY ON THE EFFECT OF SISAL FIBRE AND WASTE PLASTIC STRIPS IN STRUCTURAL STRENGTH IMPROVEMENT OF TROPICAL BLACK CLAY by YOHANNA PAUL, BADAMASI ABDULRAHMAN, ISHOLA KAZEEM, ODOH KELVIN CHUKWUEBUKA, ABDULKADIR MOHAMMED NYAKO, FWANGSHAK GAYUS MIJE

“…In the case of samples treated with waste plastic strips. The MDD progressively increased as the amount of waste plastic strips increased. …”
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Two studies in one: A propensity-score-matched comparison of fingolimod versus interferons and glatiramer acetate using real-world data from the independent German studies, PANGAEA... by Jonathan Alsop, Jennie Medin, Christian Cornelissen, Stefan Viktor Vormfelde, Tjalf Ziemssen

“…The risk of 3-month or 6-month confirmed disability progression (CDP) was reduced in PANGAEA versus PEARL (3-month: 37% reduction; hazard ratio [HR], 0.63; p < 0.001; 6-month: 47% reduction; HR, 0.53; p < 0.001). …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…., BA.5.2) were associated with more severe outcomes, while XBB and BA.2.86 showed lower pathogenicity, with a marked reduction in severe and fatal cases (P &lt; 0.05).ConclusionAs SARS-CoV-2 variants evolve, the incidence of severe cases has progressively decreased. Both XBB and BA.2.86 variants exhibit lower pathogenicity. …”
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The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma by Wu Y, Zhu J, Zhang H, Xia N

“…Group A also exhibited significantly higher rates of overall adverse events including hypertension, abdominal pain, leukopenia, thrombocytopenia, and hypoproteinemia as compared to Group B, although the incidence of hand-foot syndrome in Group A was significantly reduced as compared to Group B (13.3% vs 42.8%). The median progression-free and overall survival (PFS and OS) of patients in Group A were 13.2 and 28.8 months, with both being significantly higher than the corresponding intervals in Group B (5.7 and 10.8 months, respectively). …”
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Association of dysautonomia and different risk factors in patients with Guillain-Barré syndrome in a tertiary hospital in the Philippines by Gerald T. Pagaling, Lowrence Precious C. Dichoso, Nikolai Gil D. Reyes, Mario B. Prado

“…Abstract Background Guillain-Barré syndrome (GBS) presents with progressive ascending weakness, but it can also present with dysautonomia such as tachycardia, blood pressure fluctuations, diaphoresis, ileus, and urinary retention. …”
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Preliminary Exploration of AlF-NOTA-FAPI-04 PET/CT in the Management of Ankylosing Spondylitis: A Prospective Clinical Study by Shibo Guo MD, Zhehao Lyu PhD, Chunyu Duan MD, Hui Wang PhD, Peng Xu MD, Wei Han BD, Peng Fu PhD

“…As a potential imaging method for the early assessment of AS, positron emission tomography (PET) can quantify systemic disease activity, which is conducive to monitoring the progression of disease activity and assisting in evaluating the efficacy of the treatment. …”
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Accumulation and Distribution of Natural Gas Reservoir in Volcanic Active Area: A Case Study of the Cretaceous Yingcheng Formation in the Dehui Fault Depression, Songliao Basin, NE... by Fancheng Zeng, Bo Liu, Changmin Zhang, Guoyi Zhang, Jin Gao, Junjie Liu, Mehdi Ostadhassan

“…The intrusion of late volcanic magma provided sufficient heat for the thermal maturity progression of organic matter in Yingcheng Formation and promoted the generation of natural gas in large quantities. …”
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CT-based radiomics predicts HRD score and HRD status in patients with ovarian cancer by Yujiao Wu, Qianhui Zhang, Wenyan Jiang, Yuhua Gao, Bin Qu, Xingling Wang

“…Our findings suggest that radiomics features derived from the CT image of OC have the potential to predict HRD score and status, and the developed nomograms can enrich the range of applicable population of PARPi, prolong progression-free survival and provide personalized treatment for OC patients.…”
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Comprehensive multispectral and computational study of isoxazolidine derivative ‘ISoXD3’: Synthesis, spectral characteristics, DNA binding, and comparative effects of allyl and pro... by Ibrahim A. Alhagri, Siwar Ghannay, Norah A. Al-Suwailem, Rania Hussien Al-Ashwal, Sadeq M. AlHazmy, Sabri Messaoudi, Kaiss Aouadi

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Mirvetuximab Soravtansine in solid tumors: A systematic review and meta-analysis. by Shamsnur Rehim, Shuang Yuan, Hongjing Wang

“…The primary end-point was median progression-free survival (mPFS). The secondary endpoints were the Objective response rate (ORR) and adverse effects (AEs). …”
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Pre-sowing treatment of vetch hairy seeds, viсia villosa using ultraviolet irradiation by A. Semenov, T. Sakhno, O. Hordieieva, Y. Sakhno

“…Later in time the hydration rate progressively decreased, achieving a saturated moisture content after 700 minutes. …”
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The influence of thermal and hypoxia induced habitat compression on walleye (Sander vitreus) movements in a temperate lake by J. L. Brooks, E. J. I. Lédée, S. M. Larocque, S. J. Cooke, E. Brown, J. D. Midwood

“…The reduction of suitable habitat significantly reduced walleye movement distances, however as the summer progressed, this remaining suitable habitat warmed into their thermal optimum range which was found to increase walleye movement distances. …”
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Empowering access: unveiling an overall composite spatial accessibility index to healthcare services in Southeastern Iran by Ahmad Raeesi, Soheil Hashtarkhani, Mahmood Tara, Narjes Sargolzaei, Behzad Kiani

“…Improving geographic access is key for progressing towards universal coverage and better population health.…”
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Polystyrene nanoplastics promote colitis-associated cancer by disrupting lipid metabolism and inducing DNA damage by Shan Tian, Ruixue Li, Jiao Li, Jinhui Zou

“…PS-NPs exposure disturbed lipid metabolism and induced DNA damage via the activation of PI3K/AKT/mTOR to promote CAC progression. Inhibition of fatty acid metabolism is a therapeutic target for controlling PS-NP-induced CAC. …”
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The RNA-binding protein Puf5 and the HMGB protein Ixr1 regulate cell cycle-specific expression of CLB1 and CLB2 in Saccharomyces cerevisiae. by Megumi Sato, Varsha Rana, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

“…In normal mitotic growth, Clb2 plays the central role in the G2-M progression. We previously demonstrated that the RNA-binding protein Puf5 positively regulates CLB1 expression by downregulating expression of the repressor Ixr1. …”
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Association of genetically proxied cancer-targeted drugs with cardiovascular diseases through Mendelian randomization analysis by Chuchun Fang, Xuewei Liu, Chen Yu, Songlin Li, Xueying Liu, Shifeng Qiu, Hongbin Liang, Caiwen Ou, Jiancheng Xiu

“…Abstract Background Cancer-targeted therapies are progressively pivotal in oncological care. Observational studies underscore the emergence of cancer therapy-related cardiovascular toxicity (CTR-CVT), impacting patient outcomes. …”
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Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma by Xiang-Ming Wang, Shang-Wei Chen, Gang Chen, Hua-Fu Zhou, Ting-Qing Gan, Jing-Jing Zeng, Zu-Yun Li

“…A total of 240 genes were identified as potential target genes of miRNA-33a-5p for functional enrichment analyses; the results suggested that these target genes may participate in several vital biological processes that promote the proliferation and progression of LUSC. miRNA-33a-5p may play an essential role in the occurrence and development of LUSC by targeting hub genes (ETS1, EDNRB, CYR61, and LRRK2) derived from the PPI network. …”
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Comprehensive Analysis of the Mechanism of Anoikis in Hepatocellular Carcinoma by Dongqian Li, Qian Bao, Shiqi Ren, Haoxiang Ding, Chengfeng Guo, Kai Gao, Jian Wan, Yao Wang, MingYan Zhu, Yicheng Xiong

“…Anoikis, a type of programmed cell death, serves as a barrier against the dissemination of cancer cells to distant organs, thereby constraining the progression of cancer. Nevertheless, the mechanism of genes related to anoikis in HCC is yet to be elucidated. …”
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Adaptive Neuro-Fuzzy Inference System guided objective function parameter optimization for inverse treatment planning by Eduardo Cisternas Jiménez, Fang-Fang Yin, Fang-Fang Yin, Fang-Fang Yin

“…Once calibrated, the AI system modifies TPPs for each patient, progressing through acceptable prescription levels, from restrictive to clinically allowable. …”
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