HSPB1 Regulates Autophagy and Apoptosis in Vascular Smooth Muscle Cells in Arteriosclerosis Obliterans by Keqin Chen, Changmiao Hou, Lei Xu, Hanwu Peng, Chaogui He, Jing Liu, Guoqing Wang, Shaoshuai Huang, Xiehong Liu

“…In vivo and in vitro studies were used to determine whether HSPB1 is associated with ASO progression. The expression of HSPB1 was measured in normal and sclerotic blood vessels. …”
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Combustion Characteristics of Mui and Taru Basin Coal in a Fluidized Bed Combustor by Brian Ondari, Zachary Siagi, Anil Kumar

“…Flue gas analysis for Taru and Mui coal gave hydrogen sulfide as 20 ppm and 6 ppm, maximum carbon monoxide of 2000 ppm at 600°C, and a decrease in oxygen as combustion progressed to a minimum of 15%, followed by an increase to 20.3%, suggesting depletion of coal. …”
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Rapid Destructive Arthropathy of the Knee in Parkinson’s Disease with Pisa Syndrome: A Case of Knee-Spine Syndrome by Hirokazu Takai, Masato Kitajima, Seiko Takai, Tomoki Takahashi, Ken-ichi Katsura, Makoto Tokunaga, Susumu Watanabe

“…The radiographic findings progressed to Kellgren-Lawrence grade IV within a month. …”
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Onset of age, site and respiratory symptoms are strongly associated with respiratory decline in sporadic amyotrophic lateral sclerosis: a long-term longitudinal study by Gen Sobue, Shin-ichi Terao, Yasunobu Nosaki, Atsunori Murao, Ryota Torii, Nanayo Ogawa, Naofumi Miura, Yousuke Sasaki

“…Objective The objective of this study is to identify factors influencing progression of respiratory decline from the onset of neurological symptoms to respiratory failure in patients with amyotrophic lateral sclerosis (ALS).Methods In 100 patients with sporadic ALS, %vital capacity (%VC) was continuously measured from the first visit to the respiratory endpoint (REP). …”
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Effect of ubiquitin-specific proteinase 43 on ovarian serous adenocarcinoma and its clinical significance by Qin Li, Wenhao Li, Jiahao Wang, Wenjing Shi, Taorong Wang

“…The core aim of this investigation is to uncover genes pivotal to the progression and prognosis of ovarian cancer, while delving deep into the intricate mechanisms that govern their impact.Methods The study entailed the retrieval of RNA-seq data and survival data from the XENA database. …”
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Correlation of serum Vitamin D levels and disease severity in patients with atopic dermatitis: A hospital-based, cross-sectional study from North India by Shreya Malhan, Loveleen Kaur, Maninder Kaur, Dimple Chopra, Sharang Gupta, Snehdeep Kaur

“…Although its pathogenesis is multifactorial, Vitamin D is now postulated to play a complex and multifaceted role in the development and progression of AD. AIMS AND OBJECTIVES: This study was designed to determine the serum levels of Vitamin D in children with AD and to establish a correlation between serum Vitamin D levels and disease severity. …”
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Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma by Liyun Gao, Jiaxin Gao, Jiayin He, Wenyan Fan, Xiangxin Che, Xin Wang, Tao Wang, Chunhua Han

“…Immune contexture, which includes the tumor microenvironment (TME), plays a significant role in cancer progression and treatment. This study aimed to explore the potential impact between WTAP and ZC3H13 on the immunological characteristics of GBM. …”
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Rare Presentation of Neonatal Necrotizing Fasciitis: Case Series and Review of Literature by Kruti N Shah, Shwetal Bhatt, Dipal Zanzrukriya, Salesh K Soni

“…Conclusion: Neonatal necrotizing fasciitis is a progressive, fulminating infection of the skin, subcutaneous tissues, and fascial planes and may extend to muscular levels. …”
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Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom by Gaurav Suri, David Chandiwana, Adam Lee, Rohit Mistry

“…**Results:** In the base case, treatment with ribociclib plus letrozole increased mean progression free survival (PFS) by 4.1 months and overall survival by 5.0 months compared to palbociclib plus letrozole. …”
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Do meteorological variables impact air quality differently across urbanization gradients? A case study of Kaohsiung, Taiwan, China by Bohan Wu, Shuang Zhao, Yuxiang Liu, Chunyan Zhang

“…The results revealed that: (1) Suburban areas exhibited significantly better air quality than urban and near-urban areas, with annual AQI values of 59.58 in Meinong (outskirts), 67.86 in Renwu (suburbs area), and 76.73 in Qianjin (urban area), showing a progressive improvement in air quality from urban to suburban areas, primarily due to lower levels of urbanization and abundant forest resources; (2) Temperature and relative humidity emerged as key meteorological variables influencing AQI, with Granger causality tests indicating that temperature significantly affects AQI, especially in urban areas. …”
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A Novel Prognostic Signature Revealed the Interaction of Immune Cells in Tumor Microenvironment Based on Single-Cell RNA Sequencing for Lung Adenocarcinoma by Xing Jin, Zhengyang Hu, Qihai Sui, Mengnan Zhao, Jiaqi Liang, Zhenyu Liao, Yuansheng Zheng, Hao Wang, Yu Shi

“…Immune cells constitute a large part of the tumor microenvironment and regulate tumor progression. Our research is dedicated to studying the infiltrating immune cell in lung adenocarcinoma (LUAD) and seeking potential targets. …”
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Clinico-spirometrical correlation of newly detected COPD patients with known tobacco smoking exposure or biomass smoke exposure presenting to a teaching institution in Vadodara, Gu... by Bhavesh Patel, G Mothiganesh, Arti D. Shah, Chirag H. Chakravarti, Parshwa Naik, Princee Patel

“…Introduction: Chronic respiratory symptoms (dyspnoea, coughing, sputum production) associated with abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that result in persistent, frequently progressive airflow obstruction are the hallmarks of COPD, a diverse lung illness. …”
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Analysis of the body composition of rats with experimental diabetes mellitus type 1 and its correction by Yu. M. Kolesnyk, M. I. Isachenko

“…Two-week correction of diabetes with L-arginine and N-acetyl-L-cysteine at 8th week significantly reduces glucose concentration in subgroups, but does not affect the progressive reduction of body weight, fat and free-fat mass, and fluid volumes. …”
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Ameliorative Impact of Liraglutide on Chronic Intermittent Hypoxia-Induced Atrial Remodeling by Jun Wang, Yongzheng Liu, Changhui Ma, Yue Zhang, Meng Yuan, Guangping Li

“…Previous evidence proved that atrial anatomical remodeling (AAR) and atrial electrical remodeling (AER) are crucial for the progression and maintenance of AF. This study is aimed at investigating the impact of the glucagon-like peptide-1 (GLP-1) receptor agonist, Liraglutide (Lir), on atrial remodeling (AR) mouse model induced by chronic intermittent hypoxia (CIH). …”
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The predictive role of tertiary lymphoid structures in the prognosis and response to immunotherapy of lung cancer patients: a systematic review and meta-analysis by Xin Liu, Wu Lv, Danxue Huang, Hongxia Cui

“…The hazard ratio (HR) and corresponding 95% confidence interval (CI) for overall survival (OS), disease-free survival (DFS), recurrence-free survival (RFS), progression-free survival (PFS) and disease-specific survival (DSS) were extracted and merged with STATA 14.0. …”
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Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association by Martora F, Battista T, Giordano A, Potestio L, Megna M

“…If validated, hypergammaglobulinemia could be used to monitor disease progression and customize treatments. In conclusion, integrating immunological assessments into HS management could improve patient outcomes, particularly in younger demographics. …”
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Evidence for Decreased Nucleolar PARP-1 as an Early Marker of Cognitive Impairment by Matthew Regier, Jiancong Liang, Alexander Choi, Kavita Verma, Jenny Libien, A. Iván Hernández

“…Our data suggest that disruption of nucleolar form and function is an early and important step in the progression of cognitive impairment.…”
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Biology, genetics, and ecology of the cosmopolitan ectomycorrhizal ascomycete Cenococcum geophilum by Huayong Wang, Annegret Kohler, Francis M. Martin, Francis M. Martin

“…The capacity of this symbiont to rapidly colonize disturbed or newly formed environments promotes the development of conditions that support the growth of other plant species, thus playing a crucial role in the ecological progression and restoration of ecosystems. Several C. geophilum isolates are known to enhance the drought resistance of host plants, a trait that is becoming increasingly important in the context of climate change and frequent drought events. …”
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What are the general public’s expectations about the likely duration of common acute infections? A cross-sectional survey of Australian residents by Mark Jones, Tammy Hoffmann, Mina Bakhit, Kwame Peprah Boaitey

“…Most common reasons for care-seeking were severe or worsening symptoms, a desire for quick recovery and fear of progression to complications. After being shown typical durations, the proportion of participants who reported having no concerns waiting for spontaneous resolution while managing symptoms with over-the-counter medications ranged across the infections and was highest for common cold (68%) and lowest for UTI (31%).Conclusion Participants underestimated the duration of some infections compared with evidence-based estimates and were accurate in their estimates for other infections. …”
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Features of Crohn's Disease Depending on the Age of Disease Onset by E. G. Ganich, O. B. Shchukina

“…Not only pediatric onset, but also the onset of Crohn's disease before the age of 40 is a risk factor for the progression of the disease and its more severe course.…”
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