Optimization of Caving Technology in an Extrathick Seam with Longwall Top Coal Caving Mining by Liu Yang, Lianghui Li, Weijie Wei

“…However, different drawing sequences have a great effect on the drawing mechanism. Based on the progressive drawing sequence of cluster-group-support, this paper firstly proposes a systematic naming method for the top coal caving technology. …”
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Phytomedicine nanoformulations for Parkinson's disease by Chinthu V. Saji, K P Mohanakumar, Rajesh A Shenoi

“…This approach may be effective in addressing the underlying pathogenesis of PD, thereby slowing the disease progression.…”
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Selective epithelial expression of KRASG12D in the Oncopig pancreas drives ductal proliferation and desmoplasia that is accompanied by an immune response by Carlos P. Jara, Al-Murtadha Al-Gahmi, Audrey Lazenby, Michael A. Hollingsworth, Mark A. Carlson

“…Desmoplastic responses were evident through vimentin, α-SMA, and Masson’s trichrome staining, indicating progressive collagen deposition, particularly at the higher vector doses. …”
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Prognostic role of mesangial IgM deposition in IgA nephropathy: a long-term cohort study by Gabriel Stefan, Simona Stancu, Adrian Zugravu, George Terinte-Balcan

“…However, 37% of IgM-positive patients progressed to ESKD, significantly higher than the 11% in the IgM-negative group. …”
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First-line treatment for advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer: a network meta-analysis by Mengyao Zhang, Lan Sun

“…The primary endpoints were progression-free survival (PFS) and overall survival (OS), while secondary outcomes included objective response rate (ORR) and grade 3 or higher adverse events (≥3AEs). …”
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Yoga Practice as a Potential Sarcopenia Prevention Strategy in Indonesian Older Adults: A Cross-Sectional Study by Meiliana A, Dewi NM, Latarissa IR, Barliana MI, Alfian SD, Yulianti T, Wijaya A

“…Raya Bandung Sumedang KM. 21, Jatinangor, West Java, 45363, Indonesia, Email anna.meiliana@unpad.ac.idBackground: Sarcopenia is characterized by the progressive loss of skeletal muscle mass and poses a significant health challenge for older adults by increasing the risk of disability and decreasing quality of life. …”
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Mechanical Properties and Control Rockburst Mechanism of Coal and Rock Mass with Bursting Liability in Deep Mining by Ming-tao Gao, Zhen-qi Song, Hui-qiang Duan, Heng-qi Xin, Jian-quan Tang

“…For the fractured coal, the descending modulus Ed is relatively small, and the Ee/Ed is relatively large and presents progressive ductile failure with low probability and risk of rockburst. …”
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Six Novel ATM Gene Variants in Sri Lankan Patients with Ataxia Telangiectasia by D. Hettiarachchi, Hetalkumar Panchal, B. A. P. S. Pathirana, P. D. Rathnayaka, A. Padeniya, P. S. Lai, V. H. W. Dissanayake

“…It is characterized by progressive ataxia beginning from early childhood. The neurological deficit associated with this condition affects one’s balance, coordination, walking, and speech and can be accompanied by chorea, myoclonus, and neuropathy. …”
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Adapting self-measured blood pressure monitoring to reduce health disparities (ASPIRE): a pilot hybrid effectiveness‑implementation study protocol by Rasha Khatib, Nicole Glowacki, Iridian Guzman, Maureen Shields, Joseph Chase, Melanie Gordon

“…Results The feasibility of the study methods will be analyzed to inform a larger multi-site RCT informed by progression criteria developed in this protocol. Qualitative interviews with patients and providers will explore the appropriateness and implementation success of the toolkit using the Consolidated Framework for Implementation Research (CFIR). …”
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Prevalence and spectrum of haemoglobinopathies in females of reproductive age group- A first tertiary care center experience in Punjab, North India by Vikram Narang, Anshul Jain, Sumit Grover, Ankita Soni, Monika Narang, Ashima Taneja

“…To reduce the burden of these highly prevalent monogenic disorders, detecting them in the carrier stage is crucial to prevent disease progression. Aim: We aimed to estimate the prevalence and spectrum of hemoglobinopathies in females in the reproductive (20–40 years) age group. …”
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Oral Cancer Stem Cell-Derived Small Extracellular Vesicles Promote M2 Macrophage Polarization and Suppress CD4+ T-Cell Activity by Transferring UCA1 and Targeting LAMC2 by Lan Wu, Sai Ye, Yilin Yao, Chenping Zhang, Wei Liu

“…In conclusion, our results indicated that OSCC-CSC-sEV transfer of UCA1 promotes M2 macrophage polarization via a LAMC2-mediated PI3K/AKT axis, thus facilitating tumor progression and immunosuppression. Our findings provide a new understanding of OSCC-CSC molecular mechanisms and suggest a potential therapeutic strategy for OSCC through targeting CSC-sEVs and M2-TAMs.…”
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Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. by Hildegard Nikki Hall, Hemant Bengani, Robert B Hufnagel, Giuseppe Damante, Morad Ansari, Joseph A Marsh, Graeme R Grimes, Alex von Kriegsheim, David Moore, Lisa McKie, Jamalia Rahmat, Catia Mio, Moira Blyth, Wee Teik Keng, Lily Islam, Meriel McEntargart, Marcel M Mannens, Veronica Van Heyningen, Joe Rainger, Brian P Brooks, David R FitzPatrick

“…Classical aniridia is a congenital and progressive panocular disorder almost exclusively caused by heterozygous loss-of-function variants at the PAX6 locus. …”
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Tailored exercise and manual therapy versus standardised exercise for patients with shoulder subacromial pain: a feasibility randomised controlled trial (the Otago MASTER trial) by J Haxby Abbott, Daniel C Ribeiro, Zohreh Jafarian Tangrood, Gisela Sole, Ross Wilson

“…Participants in the standardised exercise programme received progressive strengthening exercise. The primary outcome measures were (1) the participant recruitment rate; (2) the proportion of participants enrolled from the total number screened; (3) drop-out rates; and (4) adherence to the rehabilitation programme. …”
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Climate change impacts, adaptation and mitigation in the agricultural sector by Imelda ., R. Hidayat

“…It enhances the academic impact on the progression of knowledge growth in the field of climate change adaptation and mitigation within the agricultural industry of Indonesia.…”
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PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials by Samuel Pratama, Lowilius Wiyono, Martien Silviandy Setiawan, Brigitta Cindy Lauren

“…The analysis showed increased Progression-Free Survival (PFS) (RR 0.92 (95 %CI 0.84–1.00; p=0.05)) and Objective Response Rate (ORR) (RR 1.27 (95 %CI 1.07–1.50; p=0.007)), no significant difference in Overall Survival (OS) (RR 1.03 (95 %CI 0.92–1.15; p=0.60)), and an increased risk for serious Treatment Emergent Adverse Events (TEAEs) (RR 1.13 (95 %CI 0.95–1.35; p=0.16)) in PARPi-receiving SCLC patients. …”
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A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass by Sarahi Herrera-Gonzalez, Dema Shamoon, Tingliang Shen, Simon Badin, Yatinder Bains

“…Treatment involves conventional chemo-immunotherapy consisting of R CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) or RB (rituximab and bendamustine), with the latter being better tolerated and associated with longer progression-free survival. Surgical resection is usually limited to patients in which complications are seen such as bleeding, perforation, or bowel obstruction. …”
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Authors' Reply: Commentary on “Protecting User Privacy and Rights in Academic Data-Sharing Partnerships: Principles From a Pilot Program at Crisis Text Line” by Anthony R Pisani, Carlos Gallo, Madelyn S Gould, Nitya Kanuri, John E Marcotte, Brian Pascal, David Rousseau, Megan L Ranney, Bob Filbin, Shairi Turner

“…We recognize the complexity and evolving nature of the challenges surrounding data-sharing partnerships in digital health research. As the field progresses, we remain committed to ongoing, transparent engagement and to refining best practices in collaboration with colleagues, stakeholders, and the public. …”
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Network Meta-Analysis of Once Weekly Selinexor-Bortezomib-Dexamethasone in Previously Treated Multiple Myeloma by Michael Dolph, Gabriel Tremblay, Adrienne M Gilligan, Hoyee Leong

“…**Methods**: Ovid was systematically searched for phase 2-3 randomized clinical trials (RCTs) in MM that assessed progression-free survival (PFS), overall survival (OS) and overall response rates (ORR). …”
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Development of a compact near-infrared lamp furnace for synchrotron powder diffraction and its application for in situ high-temperature observation of ferrite magnets by Shintaro Kobayashi, Shogo Kawaguchi

“…The other involves a capillary rotation system, allowing for sufficient particle statistical measurements even as crystal grain growth progresses. To demonstrate the applicability of the developed system for in situ experiments under various heating conditions, we evaluated the heating process of standard samples and in situ crystalline phase changes of Sr ferrite permanent magnet materials. …”
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Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Elutin... by Piotr Rola, Adrian Włodarczak, Mateusz Barycki, Marek Szudrowicz, Magdalena Łanocha, Jan Jakub Kulczycki, Karol Turkiewicz, Katarzyna Woźnica, Maciej Lesiak, Adrian Doroszko

“…Although percutaneous coronary intervention (PCI) continues to evolve, type 2 diabetes mellitus (T2DM) is a well-established marker of poor clinical prognosis after PCI, which is mainly attributed to the rapid progression of atherosclerosis requiring recurrent revascularizations. …”
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