Identifying fracture-controlled resonance modes for structural health monitoring: insights from Hunter Canyon Arch (Utah, USA) by G. Grechi, G. Grechi, J. R. Moore, M. E. McCreary, E. K. Jensen, S. Martino

“…<p>Progressive fracturing contributes to structural degradation of natural rock arches and other freestanding rock landforms. …”
Get full text

Prognostic Utility of Prechemoradiotherapy Albumin-to-Alkaline Phosphatase Ratio in Unresectable Locally Advanced Pancreatic Carcinoma Patients by Veysel Haksoyler, Erkan Topkan

“…The primary and secondary endpoints were the impact of the AAPR on the overall survival (OS) and progression-free survival (PFS) results, respectively. …”
Get full text

Shattering the Amyloid Illusion: The Microbial Enigma of Alzheimer’s Disease Pathogenesis—From Gut Microbiota and Viruses to Brain Biofilms by Anna Onisiforou, Eleftheria G. Charalambous, Panos Zanos

“…We discuss potential microbiome-based therapies as promising strategies for managing and potentially preventing AD progression. Fecal microbiota transplantation (FMT) restores gut microbial balance, reduces Aβ accumulation, and improves cognition in preclinical models. …”
Get full text

Lithuanian Scientific Medical Periodicals in the Third-Fifth Decade of the 20th Century (till 1944) by Silvija Stakulienė

“…Due to their knowledge and experience, Lithuanian physicians were among the progressive ideas and scientific innovations propagating European representatives. …”
Get full text

Novel hormonal agents in men with metastatic castration resistant prostate cancer and reduced performance status: Experiences of a specialized single center by Thomas Büttner, Philipp Lossin, Stefan Latz, Carolin Jacobs, Philipp Krausewitz, Stefan Hauser

“…Abstract Objectives Attaining castration resistance in metastatic prostate cancer (mCRPC) represents a pivotal juncture in the progression of the patient's illness and treatment regimen. …”
Get full text

MDFGNN-SMMA: prediction of potential small molecule-miRNA associations based on multi-source data fusion and graph neural networks by Jianwei Li, Xukun Zhang, Bing Li, Ziyu Li, Zhenzhen Chen

“…Abstract Background MicroRNAs (miRNAs) are pivotal in the initiation and progression of complex human diseases and have been identified as targets for small molecule (SM) drugs. …”
Get full text

Optimal Solar‐Biomass‐Diesel‐Generator Hybrid Energy for Water Pumping System Considering Demand Response by Olumuyiwa Taiwo Amusan, Nnamdi Ikechi Nwulu, Saheed Lekan Gbadamosi

“…The demand for this essential commodity is progressively growing around the world. Incorporating renewable energy sources (RES) into its operation mitigates adverse environmental effects stemming from greenhouse gas (GHG) emissions and reduces associated costs linked to fossil fuel energy sources. …”
Get full text

Association of serum neurofilament light chain with cognitive impairment: findings from the National Health and Nutrition Examination Survey by Tianjiao Meng, Qinwen Fei, Tian Lv, Shiqin Chen

“…BackgroundSerum Neurofilament Light chain (NfL) is a promising biomarker of neuronal damage, used to assess the extent of neuronal injury and neurodegeneration, and it is widely applied in the diagnosis of neurodegenerative disease and monitoring disease progression. This article aims to determine whether serum NfL associated with cognitive level.MethodsUsing NHANES data, we conducted an analysis of cognitive test results for 450 adults aged 60 years and older and examined their correlation with serum NfL levels. …”
Get full text

High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer by Lin Qin, Kai Sun, Li Shi, Yushan Xu, Rongping Zhang

“…A high-fat mouse model was constructed, and then, a subcutaneous tumorigenesis mouse model of carcinoma of pancreatic cells and a metastatic neoplasm mouse pattern of pancreatic carcinoma cells injected through the tail vein were constructed to explore whether abnormal lipid metabolism affects the progression of pancreatic cancer in mice. We constructed a high-lipid model of pancreatic carcinoma cell lines and knockdown and overexpressed enolase in pancreatic carcinoma cell lines and investigated whether high lipid regulates epithelial-mesenchymal transition (EMT) by upregulating enolase (ENO), thereby promoting the cells of pancreatic carcinoma to invade and migrate. …”
Get full text

Combined Use of Excimer Laser and High-Speed Rotational Atherectomy to Overcome a Severely Calcified Lesion in Endovascular Therapy by Keisuke Nakabayashi, Shinya Hata, Nobuhito Kaneko, Akihiro Matsui, Kazuhiko Tanaka, Hiroshi Ando, Minoru Shimizu

“…With the antegrade wire progressing into the subintimal space, direct distal-SFA puncture was performed and wire externalization was established. …”
Get full text

Real-time detection and monitoring of public littering behavior using deep learning for a sustainable environment by Eaman Alharbi, Ghadah Alsulami, Sarah Aljohani, Waad Alharbi, Somayah Albaradei

“…Through a series of experiments, we progressively improved the model’s performance, achieving accuracy rates of 93.42% in the first experiment, 95.53% in the second, and ultimately reaching 99.5% in the third experiment. …”
Get full text

From Night to Light: A Bibliometric Analysis of the Global Research Trajectory of Sleep Disorders in Parkinson&rsquo;s Disease by Shi L, Zhao X, Wu J, He C

“…Luya Shi,1,2 Xinxin Zhao,3 Jing Wu,3 Caidi He1 1Department of Nursing, Municipal Hospital Affiliated to Taizhou University, Taizhou, Zhejiang, 318000, People’s Republic of China; 2Department of Post Graduate School of Nursing, Sehan University, Yeonggam, 58447, South Korea; 3Department of Nursing, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, People’s Republic of ChinaCorrespondence: Caidi He, Municipal Hospital Affiliated to Taizhou University, Taizhou, Zhejiang, 318000, People’s Republic of China, Email hcdeye@gmail.comPurpose: Sleep disorders are prevalent non-motor symptoms in patients with Parkinson’s disease (PD), significantly diminishing the overall quality of life for patients and potentially accelerating the deterioration of motor and cognitive functions, accelerating disease progression. Despite increasing research on sleep disorders in PD, a comprehensive analysis of the knowledge structure and key issues in this field are still lacking. …”
Get full text

Impact of kidney volume on incidence of in-hospital kidney-related adverse outcomes in patients with acute heart failure by Akira Saito, Taku Asano, Nobuyuki Komiyama, Sachiko Ohde

“…Abstract Background Recent studies revealed an association between small kidney volume and progression of kidney dysfunction in particular settings such as kidney transplantation and transcatheter aortic valve implantation. …”
Get full text

Analysis of intracranial lesions in patients with HIV-associated cryptococcal meningitis by Wei Song, Li Liu, Tangkai Qi, Zhenyan Wang, Yang Tang, Jianjun Sun, Shuibao Xu, Junyang Yang, Jiangrong Wang, Jun Chen, Renfang Zhang, Yinzhong Shen

“…Patients with lesion progression showed higher levels of IFN-γ, IL-4, IL-5, IL-6, IL-1Ra, IL-1β, GM-CSF, Eotaxin, and Basic FGF in cerebrospinal fluid after four weeks of treatment.ConclusionIntracranial lesions in HIV-associated cryptococcal meningitis patients are mostly due to Cryptococcus and Mycobacterium infections. …”
Get full text

Development and Validation of the Pediatric Well-Being Picture Scale© Using a Mixed-Methods Research Design by Judith Quaranta, Rosa Darling, Mei-Hsiu Chen, Julia DeMartino, Madison Kozlowski

“…This highlights the need for early identification and intervention of decreased well-being to prevent progression to potential mental health issues. The purpose of our research was to develop the Pediatric Well-Being Picture Scale© (PWBPS©), the first picture-based screening tool for ages 8–11 years, accessible to children regardless of their literacy, language skill, and developmental levels, allowing for quick screening for early referral and intervention. …”
Get full text

Effects of nitrogen fertilizer application rate on lodging resistance for rice (Oryza sativa L.) stem by Yuya Lu, Jiehao Cui, Shuying Bao, Weiyang Liu, Yanqiu Geng, Xuanhe Liang, Shangze Li, Liying Guo, Xiwen Shao

“…Moreover, the lodging index increased progressively with higher nitrogen fertilizer application rates, reaching its maximum under the N5 treatment, which corresponded to an increased lodging risk. …”
Get full text

Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis by Muhammad Osama, Muhammad Haris Khan, Safeena Khan, Amna Hussain, Ammara Tahir, Mehran Ullah, Abdullah Afridi, Ubaid Ullah, Wajeeh Ur Rehman

“…The primary outcomes were progression-free survival (PFS) and minimal residual disease (MRD) status. …”
Get full text

Dyskryminacja dzieci pozamałżeńskich w ustawodawstwie cywilnym w Drugiej Rzeczypospolitej i próby jej przezwyciężenia w projektach kodyfikacyjnych by Leonard Górnicki

“…The author argues that the drafts in Stanisław Gołąb’s original version were more progressive, since at their core was the fundamental equality of rights between children born during marriage and non marital children, while the Subcommittee gave this a more declarative form by assuming that a child born out of wedlock could be equated with a marital child by order of the court (office) of guardianship, issued at the request of the authorized subjects and with the consent of the persons indicated therein. …”
Get full text

Cyclosporine A causes gingival overgrowth via reduced G1 cell cycle arrest in gingival fibroblasts. by Reiri Takeuchi, Takatoshi Nomura, Manabu Yaguchi, Noriko Kuwahara, Yuta Amino, Chieko Taguchi, Itaru Suzuki, Haruka Suzuki, Teruaki Nagashima, Kazumune Arikawa, Yuichiro Okada, Takato Nomoto, Koichi Hiratsuka

“…DNA damage), cell cycle progression is arrested in the G1 phase until the completion of damage restoration. …”
Get full text

The value of growth differentiation factor 15 as a biomarker for peripheral artery disease in diabetes patients by Wan-Chi Chuang, Chih-Hsun Chu, Cai-Sin Yao, Mei-Chih Wei, I-Lun Hsieh, Chia-Mei Liao

“…Increased GDF15 levels are associated with obesity, insulin resistance, and diabetes as well as a poorer diabetes progression and prognosis. This is a prospective cohort study investigated the association between circulating GDF15 and diabetic peripheral artery disease. …”
Get full text