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16181
RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients
Published 2024-10-01“…The metabolic pathway of polyamines is crucial in breast cancer progression, with a strong association to the increased capabilities of tumor cells for proliferation, invasion, and metastasis. …”
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16182
Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study
Published 2025-01-01“…While evidence suggests that MetS and its components may influence the development of osteoarthritis (OA), the specific relationship between MetS and the likelihood of progressing to a stage of OAK that requires Total knee replacement (TKA) remains underexplored. …”
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16183
Prognostic analysis of helical tomotherapy stereotactic body radiotherapy in multiple primary or second primary lung cancers
Published 2025-01-01“…Cancer-specific survival (CSS) and progression-free survival (PFS) were assessed using Kaplan-Meier analysis and log-rank tests. …”
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16184
MicroRNA-150-3p enhances the antitumour effects of CGP57380 and is associated with a favourable prognosis in non-small cell lung cancer
Published 2025-01-01“…Abstract MicroRNA (miRNA) dysregulation has been identified in several carcinomas, including non-small cell lung cancer (NSCLC), and is known to play a role in the development and progression of this disease. We initially conducted a miRNA microarray analysis, which revealed that the MNK inhibitor CGP57380 increased the expression of miR-150-3p. …”
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16185
Efficacy and safety of neoadjuvant bevacizumab plus chemotherapy in locally advanced gastric cancer patients: a retrospective, comparative study
Published 2025-01-01“…Results Objective response rate (52.2% vs. 35.4%), disease control rate (91.3% vs. 81.3%), surgical resection rate (95.7% vs. 85.4%), R0 resection rate (87.0% vs. 75.0%), and the proportion of patients with tumor regression grade 0–1 (31.8% vs. 17.1%) tended to increase in bevacizumab plus chemo group versus chemo group, although there was no statistical significance. The 48-month progression-free survival (PFS) rates were 58.3% and 33.4% in bevacizumab plus chemo group and chemo group. …”
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16186
PHARC syndrome: an overview
Published 2024-11-01“…Abstract PHARC, polyneuropathy, hearing loss, cerebellar ataxia, retinitis pigmentosa and cataracts, or PHARC is a very rare progressive neurodegenerative autosomal recessive disease caused by biallelic mutations in the ABHD12 (a/b-hydrolase domain containing 12) gene, which encodes a lyso-phosphatidylserine (lyso-PS) lipase. …”
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16187
Persistence with Early-Line Abatacept versus Tumor Necrosis Factor-Inhibitors for Rheumatoid Arthritis Complicated by Poor Prognostic Factors
Published 2021-05-01“…In adjusted analyses, abatacept patients had a lower risk of discontinuing index treatment due to disease progression (0.3 \[95% confidence interval (CI): 0.1-0.6\], *P*=0.001). …”
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16188
Clinical value of serum biomarkers, squamous cell carcinoma antigen and apolipoprotein C-II in follow-up of patients with locally advanced cervical squamous cell carcinoma treated...
Published 2021-01-01“…In this multicenter prospective cohort study, the usefulness of pre- and posttreatment serum protein levels of potential biomarkers, including squamous cell carcinoma antigen (SCC-Ag), apolipoprotein C-II (ApoC-II), matrix metalloproteinase (MMP)1, and MMP2, were evaluated together with clinical factors in 145 cervical cancer patients in order to determine their suitability to predict survival. Progression-free survival (PFS) was the primary endpoint, and overall survival (OS), pelvic PFS (PPFS), and distant metastasis-free survival (DMFS) were the secondary endpoints. …”
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16189
Effects of Resistant Starch on Patients with Chronic Kidney Disease: A Systematic Review and Meta-Analysis
Published 2022-01-01“…Recent studies shown that the progression of CKD may be related to the change of intestinal flora. …”
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16190
Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better
Published 2022-01-01“…ICB treatment outcomes were analyzed by overall survival, progression-free survival and objective response rate.Results No universally valid TMB cut-off was available for all cancer types. …”
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16191
High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma
Published 2023-01-01“…Our study suggested TET1 as a potential indicator in HCC progression. TET1 was closely involved in immune infiltration and activation of oncogenic pathways. …”
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16192
Reperfusion injury or cytokine storm? Utilizing plasmapheresis in severe trauma-induced multiorgan failure: a case report
Published 2024-12-01“…However, plasmapheresis may represent an effective treatment option in cases of severe progression.…”
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16193
Civil servants' activity regulation in Lithuania 1918-1940
Published 2010-06-01“…Public discussion and ideas of scholars were rather modern, progressive, and reminded ideas of famous authorities of management. …”
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16194
Plasma-derived extracellular vesicles prime alveolar macrophages for autophagy and ferroptosis in sepsis-induced acute lung injury
Published 2025-02-01“…These findings suggest a novel mechanism of plasma-AM interaction in sepsis-induced ALI, offering a plausible strategy for assessing septic progression and treating lung injury.…”
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16195
Immunohistochemical expression of parathyroid hormone-related protein and ezrin in invasive breast carcinoma of no special type: a retrospective analysis
Published 2025-01-01“…Conclusion The study highlights the significant roles of PTHrP and ezrin in breast cancer progression. Elevated levels of these proteins are associated with more aggressive disease, suggesting their capability as prognostic indicators and treatment targets in breast cancer. …”
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16196
Association of Fatty Acid Synthase with Level of Fatty Acids in Osteoporosis Patients
Published 2025-01-01“…In conclusion, the parameters of FAS, HDL, VLDL, TG, TAS, and TOS were effective in monitoring the progression of osteoporosis, as well as fatty acid level. …”
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16197
La bibliothèque dans Buffy contre les vampires : grimoires et merveilles
Published 2010-01-01“…Elle s’avère incontournable pour la progression dramatique de la diégèse et l’installation des systèmes de représentation mythologiques. …”
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16198
Numerical Analysis on the Load Sharing Performance of Long-Short CFG Pile Composite Foundation Subjected to Rotation of Adjacent Retaining Wall
Published 2021-01-01“…It is revealed that to arrive at a new static equilibrium during progression of wall rotation, the percentage load sharing ratios of the long and short piles change increasingly while the load proportion carried by the upper soil reduces remarkably. …”
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16199
Does water quality matter? Foraging activity of Daubenton’s bat (Myotis daubentonii) over three lakes with different trophy
Published 2024-12-01“…Hence, the observed slow increase in the number of M. daubentonii over the past 20 years cannot be attributed to, as previously suggested, eutrophication, but, on the contrary, seems to be a result of a progressive improvement in the environment. …”
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16200
Clinical features, pathological characteristics, and prognosis of patients with IgA nephropathy complicated with nephrotic syndrome
Published 2025-01-01“…Renal endpoint was defined as a 50% decrease in estimated glomerular filtration rate or progression to end-stage renal disease. A total of 207 patients with IgAN and NS were categorized into four pathological groups: IgAN with mesangial proliferative glomerulonephritis (IgAN-MsPGN) (n = 150), IgAN with minimal change disease (IgAN-MCD) (n = 49), IgAN with membranous nephropathy (IgAN-MN) (n = 7), and IgAN with membranoproliferative glomerulonephritis (IgAN-MPGN) (n = 1). …”
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