Prospective Multicenter Open-Label One-Arm Trial Investigating a Pumpkin Seed, Isoflavonoids, and Cranberry Mix in Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia: A Pilo... by Elie Nemr, Elie El Helou, Georges Mjaess, Albert Semaan, Josselin Abi Chebel

“…Phytotherapy for lower urinary tract symptoms (LUTSs) due to benign prostate hyperplasia (BPH) is progressively demanded by patients and trusted by physicians. …”
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Effects of spectral manipulations of music mixes on musical scene analysis abilities of hearing-impaired listeners. by Aravindan Joseph Benjamin, Kai Siedenburg

“…Therefore, baseline performance progressively declined to chance-level at moderately severe degrees of hearing loss thresholds, independent of target category. …”
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Computer simulation of the soil water regime under an apple orchard in a mountainous area (using the example of the leached chernozem of the experimental agricultural station Gorno... by Svetlana V. Baboshkina, Olga A. Elchininova, Alexander V. Puzanov, Tamara A. Rozhdestvenskaya

“… Relevance. Progressive degradation of farmland soils – erosion, salinization, desertification. …”
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Pregnancy-Associated Plasma Protein A Induces Inflammatory Cytokine Expression by Activating IGF-I/PI3K/Akt Pathways by Weiping Li, Hongwei Li, Li Zhou, Zijian Wang, Bing Hua

“…Together, this study demonstrates that PAPP-A activates the macrophage signaling pathway (IGF-I/PI3K/Akt), which drives the expression and production of inflammatory cytokines known to contribute to the initiation and progression of ACS. These findings indicate that PAPP-A may play a proinflammatory role in the pathophysiology of ACS and serve as a potential therapeutic target.…”
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Integrative single-cell and multi-omics analyses reveal ferroptosis-associated gene expression and immune microenvironment heterogeneity in gastric cancer by Shupeng Zhang, Zhaojin Li, Gang Hu, Hekai Chen

“…Abstract Gastric cancer (GC), a prevalent malignancy worldwide, encompasses a multitude of biological processes in its progression. Recently, ferroptosis, a novel mode of cell demise, has become a focal point in cancer research. …”
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Transthyretin-Related Familial Amyloidosis Polyneuropathy with Spinal Cord Damage: A Case Report by Liu H, Huang C, Du Y, Liu J, Ren X, Wang H, Ye J, Zhou H, Duan Z

“…The disease is characterized primarily by peripheral and autonomic nerve damage. Disease progression is associated with frequent involvement of the heart, lungs, kidneys, eyes, and other organs. …”
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KLEBSIELLA PNEUMONIAE NECROTIZING FASCIITIS OF THE LOWER EXTREMITY IN A 7-MONTH-OLD MALE: A CASE REPORT by Marelno Zakanito, Iswinarno Doso Saputro

“…Abstract: Introduction:  Klebsiella   pneumoniae   necrotizing   fasciitis   is   an uncommon soft tissue infection characterized by rapidly progressing necrosis involving the skin, subcutaneous tissue, and fascia. …”
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Long noncoding RNAs predict the survival of patients with colorectal cancer as revealed by constructing an endogenous RNA network using bioinformation analysis by Hui Zhang, Zhuo Wang, Jianzhong Wu, Rong Ma, Jifeng Feng

“…Abstract Long noncoding RNAs (lncRNAs) are aberrantly expressed in various cancers types and can function as competing endogenous RNAs (ceRNAs), which promote and maintain tumor initiation and progression. In this study, we explored the functional roles and regulatory mechanisms of lncRNAs as ceRNAs in colorectal cancer and their clinical potential as biomarkers. …”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…Ccl3 and Lcp1 might potentially modulate IS progression by influencing SASP, proffering novel prospects for IS clinical diagnosis and treatment.…”
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Impact of corticosteroids on the efficacy of first-line pembrolizumab plus chemotherapy in patients with advanced non-small-cell lung cancer by Amytis Roboubi, Eric Wasielewski, Soraya Bordier, Amélie Turlotte, Geoffrey Pavaut, Arnaud Scherpereel, Alexis Cortot, Clément Gauvain

“…Methods: The primary endpoint was progression-free survival (PFS) according to SC exposure status (⩾10 mg/day), adjusted in a multivariate Cox model for the following confounders: age, performance status, hospital admission prior to treatment, number of metastatic sites, brain metastases, bone metastases, PD-L1 status, and histological subtype. …”
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Systemic inflammation response index association with gout in hyperuricemic adults: NHANES 2007–2018 by Xiaochan Tian, Guixing Zeng, Junping Wei

“…Previous studies have indicated that specific strategies may be effective in preventing the progression of hyperuricemia to gout. However, there is a lack of widely applicable methods for identifying high-risk populations for gout. …”
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Network analysis of meaning in life, perceived social support, and depressive symptoms among vocational undergraduate students by Sen sen Zhang, Sen sen Zhang, Wen hua Zhang, Shao hong Yong, Shao hong Yong, Jia tai Chen

“…The present study aimed to investigate the association between meaning in life (MIL) and perceived social support (PSS) with depressive symptoms among vocational undergraduate students, employing a network analysis approach to gain a deeper understanding of the underlying pathways and to prevent the progression of depressive symptoms into disorders.MethodsA total of 1367 Chinese vocational undergraduates (Mage = 20.1, SD = 1.6; 44.7% female) were recruited and were asked to complete a series of questionnaires, including the meaning in life questionnaire, perceived social support scale, and patient health questionnaire. …”
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Associations between systemic inflammatory biomarkers and metabolic dysfunction associated steatotic liver disease: a cross-sectional study of NHANES 2017–2020 by Xin Qiu, Shuang Shen, Nizhen Jiang, Yifei Feng, Guodong Yang, Donghong Lu

“…Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a primary cause of chronic liver disease, with potential progression to cirrhosis and hepatocellular carcinoma (HCC). …”
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AMPD1 and MTHFR genes are not associated with calcium levels in rheumatoid arthritis patients with methotrexate therapy in Indonesia by Dika P. Destiani, Sumartini Dewi, Syed A. S. Sulaiman, Sofa D. Alfian, Melisa I. Barliana, Rizky Abdulah

“…Abstract Rheumatoid Arthritis (RA) is a chronic and progressive autoimmune disease that affects synovial tissues has greater risk of developing secondary osteoporosis (OP). …”
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Tracing the Intellectual History of the Knowledge Economy: An Analysis of OECD Publications within the International Political Economy Framework by V. I. Konnov, D. A. Talagaeva

“…Consequently, the “knowledge economy” progressively receded from the purview of OECD documents in the 2010s, giving way to the emergence of the concept of the “digital economy.”…”
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Comparison of Morphological and Functional MRI Assessments of Periprostatic Fat for Predicting Prostate Cancer Aggressiveness by David Freire Maia Vieira, Cecília Vidal de Souza Torres, André de Freitas Secaf, Matheus de Moraes Palma, Gabriel de Lion Gouvea, Jorge Elias Júnior, Rodolfo Borges Reis, Valdair Muglia

“…Using the Cox model, dPSA (p<0.01), systemic disease at diagnosis (p<0.01), and mean ADC (p<0.02) were independent predictors of overall survival (OS). For progression-free survival (PFS), only dPSA (p<0.01) and systemic disease at diagnosis (p<0.01) were significant predictors. …”
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A systemic analysis of Creutzfeldt Jakob disease cases in Asia by Urwah Rasheed, Sana Khan, Minahil Khalid, Aneeqa Noor, Saima Zafar

“…Creutzfeldt Jakob Disease (CJD) is a rapidly progressive, fatal neurodegenerative disorder, also known as a subacute spongiform encephalopathy. …”
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CONCERNING THE USE OF INFORMATION AND COMMUNICATION TECHNOLOGIES BY THE SECRETARIAT OF THE CONSTITUTIONAL COURT OF UKRAINE IN PERFORMING ITS FUNCTIONS by Darya Barvitska

“…Digitization of all spheres of public life, in particular the progressive development of e-justice, should definitely affect the legal regulation of relevant processes in the Court’s Secretariat.…”
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Risk factors of chronic kidney disease in cisplatin-based hyperthermia intraperitoneal chemotherapy by Chih-Chung Cheng, Hung-Chieh Yeh, Pei-Wen Su, Chien-Lin Ho, Sheng-Chi Chang

“…Univariate and multivariate analyses were conducted to confirm the correlation between different variables and CKD occurrence.Results Of the 55 patients, 24 (43.6%) patients developed AKI and 17 (70.8%) patients of these AKI patients progressed to CKD. Multivariate regression analysis identified intraoperative use of parecoxib (Odds Ratio (OR) = 4.39) and intraoperative maximum temperature > 38.5°C (OR = 6.40) as major risk factors for cisplatin-based HIPEC-related CKD occurrence. …”
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Post-traumatic enophthalmos: diagnosis and rehabilitation by M.B. Gushсhina, D.S. Afanasyeva

“…Considering current materials for plastic surgery, surgical techniques for enophthalmos correction, and risk factors for post-traumatic enophthalmos development in the late period, it seems to be important to develop single-step surgical strategy for orbital reconstruction, correction of enophthalmos, and prevention of its further development and/or progression.</i> </p> <p> <i>This paper is based on the data published in the last decade. …”
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