Exploring the impact of insufficient thermal ablation on hepatocellular carcinoma: NDST2 overexpression mechanism and its role in facilitating growth and invasion of residual cance... by Weijun Wan, Danxia Guo, Tong Kang, Jinshu Pang, Yunjing Pan, Jiamin Chen, Wei Liao, Yuji Chen, Peng Lin, Lipeng Li, Hong Yang, Yun He

“…Knockdown of NDST2 in heat stress-induced liver cancer cells results in growth inhibition associated with gene downregulation.Conclusion The upregulation of NDST2 can accelerate the progression of residual HCC after ITA, suggesting a potential role for NDST2 in the therapeutic efficacy and prognosis of residual HCC.…”
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Characteristics of NAFLD Based on Hypopituitarism by Kazuhisa Kodama, Atsuhiro Ichihara, Yasufumi Seki, Yuichi Ikarashi, Takaomi Sagawa, Tomomi Kogiso, Maiko Taniai, Katsutoshi Tokushige

“…The hepatic fibrosis grade rapidly progressed in the cranial surgery cases of NAFLD patients with hypopituitarism, possibly in association with BMI, diabetes mellitus, and leptin. …”
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Acupuncture Treatment in Elderly People with Sarcopenia: Effects on the Strength and Inflammatory Mediators by Gisele Soares Mendes Damasceno, Thaís Helena Machado Marçal Teixeira, Vinicius Carolino de Souza, Tiago Sousa Neiva, Karina Prudente Pereira, Maria de Fátima Teles Landim, Gislane Ferreira de Melo, Juliana de Faria Fracon e Romão, Otávio Tolêdo Nóbrega, Gustavo de Azevedo Carvalho

“…Sarcopenia is defined as the progressive loss of skeletal muscle mass, associated with aging. …”
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Clinical outcomes of dogs with high-grade cutaneous mast cell tumors by Siew Mei Ong, Siew Mei Ong, Charly McKenna, Christopher Pinard, Christopher Pinard, Christopher Pinard, Christopher Pinard, Danielle Richardson, Michelle L. Oblak

“…Despite aggressive treatment, 75% of the dogs that received concurrent surgical and adjuvant therapy experienced disease progression. Lymph node extirpation, tumor localization, number of tumors, and local recurrence were not associated with the overall outcome.Clinical relevanceThe combination of aggressive local therapy and adjuvant systemic chemotherapy provides a notable survival benefit in dogs with HGMCTs. …”
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Impact of solid fuel use on asthma prognosis and consistent peak expiratory flow changes: Evidence from China by Yuexi Chen, Shuojia Xie, Xirong Chen, Xiaowen Zhong, Linhang Yang, Weitong Lin, Junfeng Huang, Ruchong Chen

“…Yet the connection between use of such fuels and the incidence as well as the progression of asthma needs further clarification. This investigation endeavors to conduct an integrative cross-sectional and longitudinal study to examined the link between solid fuel utilization and asthma. …”
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Associations of plasma biomarkers with cerebral perfusion and structure in Alzheimer’s disease by Yong He, Xiaojiao Liu, Fang Liu, Ping Che, Yanxin Zhang, Ruxue Fan, Yuan Li, Wen Qin, Nan Zhang

“…Plasma biomarkers exhibited varied correlations with brain perfusion, GM volume, and WM integrity and predicted their longitudinal changes in AD patients, suggesting their potential to reflect functional and structural changes and to monitor pathophysiological progression in the brain.…”
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Severe fever with thrombocytopenia syndrome complicated with aspergillus endocarditis and multiple organ infarctions after glucocorticoid treatment in an immunocompetent man: a cas... by Yuxi Zhao, Xiaoxin Wu, Xinyu Wang, Lanjuan Li

“…Here, we present the first case of an immunocompetent patient with SFTS who progressed to IPA and Aspergillus endocarditis after glucocorticoid treatment, and embolism of the vegetations from the left ventricle led to multiple infarctions in the brain, kidney, and spleen. …”
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SMR-guided molecular subtyping and machine learning model reveals novel prognostic biomarkers and therapeutic targets in non-small cell lung adenocarcinoma by Baozhen Wang, Yichen Yin, Anqi Wang, Weidi Liu, Jing Chen, Tao Li

“…Functional enrichment analysis revealed the complex interplay of cell cycle regulation, DNA repair, immune response, and metabolic reprogramming in the progression of LUAD. Furthermore, we observed a strong correlation between risk scores and the expression of specific cytokines, such as CCL17, CCR2, and CCL20, suggesting novel avenues for developing cytokine network-based therapeutic strategies. …”
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Tracheal Resection for Critical Airway Obstruction in Morquio A Syndrome by Claire Frauenfelder, Elizabeth Maughan, Johnny Kenth, Reema Nandi, Simon Jones, Robert Walker, Bill Walsh, Nagarajan Muthialu, Iain Bruce, Richard Hewitt, Colin Butler

“…An urgent need has developed to consider alternatives to palliation of progressive tracheal obstruction to preserve and maintain these patients’ hard-won good quality of life, as well as to facilitate spinal and other required surgery. …”
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Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer by Xiao-xiang Yu, Yi Liu, Rong-jiang Luo, Zi-xuan Song, Wen-kai Chen, Zeng-mi Mo, Feng-jing Wang

“…Inhibition of ILK expression would be a promising method for treating the development and progression of PCa.…”
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Shorter telomere length in COPD cases secondary to biomass-burning smoke exposure by Angélica Domínguez-de-Barros, Gloria Pérez-Rubio, Ingrid Fricke-Galindo, Alejandra Ramírez-Venegas, Malena Gajate-Arenas, Rafael Hernández-Zenteno, Salvador García-Carmona, Robinson Robles-Hernández, María E. Ramírez-Díaz, Filiberto Cruz-Vicente, María L. Martínez-Gómez, Jacob Lorenzo-Morales, Ramcés Falfán-Valencia, Elizabeth Córdoba-Lanús

“…Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow obstruction and destruction of lung tissue, primarily attributed to tobacco smoking. …”
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The effects of different egg yolk concentrations used with soy bean lecithin-based extender on semen quality to freeze bull semen by Serpil Sariozkan, Purhan Barbaros Tuncer, Mustafa Numan Bucak, Serhat Buyukleblebici, Huseyin Kinet, Ali Bilgen

“…<p> <b>Results:</b> In Simmental bulls, semen extended with B5 had significantly higher CASA motility and CASA progressive motility than those extended with the rest of extenders after freezing and thawing (p<0.001). …”
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Phycospheric Bacteria Alleviate the Stress of Erythromycin on <i>Auxenochlorella pyrenoidosa</i> by Regulating Nitrogen Metabolism by Jiping Li, Ying Wang, Yuan Fang, Xingsheng Lyu, Zixin Zhu, Chenyang Wu, Zijie Xu, Wei Li, Naisen Liu, Chenggong Du, Yan Wang

“…As the exposure time progressed, the nitrate reductase activities of the microalgae gradually increased, but remained significantly lower than that of the control group at 21 d. …”
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Evidence and perspectives on miRNA, circRNA, and lncRNA in myocardial ischemia-reperfusion injury: a bibliometric study by Xiaowen Bo, Qiuyu Li, Siyuan Chen, Tian Zhou, Ning Yin, Wenpeng Song, Donghui Zhao, Jinghua Liu, Qian Fan

“…Abstract Objective miRNA, circRNA, and lncRNA play crucial roles in the pathogenesis and progression of myocardial ischemia-reperfusion injury (MI/RI). …”
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Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

“…CD36 overexpression favors progression of different pathologies, such as atherosclerosis and cancer. …”
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Effects of Resveratrol on the Kidney in Rats with Streptozotocin Induced Diabetic Nephropathy by Duygu Tozcu, Çiğdem Özer, Aydan Babül, Sevim Ercan, Ergin Dileköz, Gülnur Take Kaplanoğlu, Güleser Göktaş

“…Conclusion: RSV may protect against diabetic nephropathy by modulating key pathways involved in renal degeneration and vascular function and may have potential as a therapeutic agent for slowing disease progression.…”
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SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1 by Zheng Bin, Wang Gang, Gao Wenbo, Wu Qiquan, Zhu Weizhi, Weng Guobin

“…MTT assay was used to investigate the cytotoxic effects of PD. Cell cycle progression was analyzed using propidium iodide (PI) staining, and protein levels were assayed by Western blot analysis. …”
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Long-term results of antiviral therapy in patients with chronic hepatitis C with sustained virologic response by T. M. Ignatova, T. N. Lopatkina, V. P. Chulanov, Ye. V. Gaydasheva, S. N. Batskikh, G. V. Mikhaylovskaya, D. T. Abdurakhmanov, S. Yu. Karpov, Ye. N. Nikulkina, O. A. Chernova

“…At patients who have achieved SVO as a result of AVT, late relapses of HCV-infection are rare and in the majority no disease progression was found. Relapses of cryoglobulinemia syndrome were observed, but data on presence of latent HCV-infection were not received. …”
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Selective engagement of long-latency reflexes in postural control through wobble board training by Theodore Deligiannis, Mahsa Barfi, Brian Schlattmann, Ken Kiyono, Damian G. Kelty-Stephen, Madhur Mangalam

“…Wobble board increased engagement of LLRs and decreased engagement of compensatory postural adjustments (CPAs), indicated by the peak in non-Gaussianity of CoP planar displacements over LLR-specific timescales (50–100 ms) and non-Gaussianity of CoP planar displacements progressively diminishing over CPA-specific timescales ( $$>100$$ ms). …”
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Percutaneous closure of a traumatic ventricular septal defect: a case report and literature review by Camilo Andres Calderon-Miranda, Maria Juliana Reyes-Cardona, Gabriel Roberto Lopez-Mora, Fernando Andrés Guerrero-Pinedo, Jairo Sanchez-Blanco, Carlos Enrique Vesga-Reyes, Jorge Alexander Zambrano-Franco, Pastor Olaya

“…Symptomatic septal defects, those 10 mm or larger, with Qp: Qs greater than 1.5, or causing complications such as pulmonary hypertension or valvular involvement, are usually closed to prevent progression of heart failure. Management of traumatic VSD has traditionally been surgical. …”
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