Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways by Xiao Chen, Luping Lin, Qiaoling Wu, Sang Li, Huihui Wang, Yang Sun

“…In addition, to further investigate the effect of TNF-α on the progression of cervical cancer, a C33A subcutaneous xenograft model was established in vivo. …”
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Human Neutrophil Defensins Disrupt Liver Interendothelial Junctions and Aggravate Sepsis by QiXing Chen, Yang Yang, YiHang Pan, LiHua Shen, Yan Zhang, Fei Zheng, Qiang Shu, XiangMing Fang

“…However, direct evidence for the pathogenic role of HNP1-3 proteins during sepsis progression is lacking. In current study, sepsis was induced by means of cecal puncture and ligation. …”
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Uremic Leontiasis Ossea due to Resistant Secondary Hyperparathyroidism by Kubra Tuna, MD, Olesya Ilkun, MD, PhD, Peter T. Dziegielewski, MD, Anu Sharma, MD

“…Background/Objective: Severe progressive overgrowth of the facial bones known as uremic leontiasis ossea (ULO) is a rare complication of resistant hyperparathyroidism in end-stage renal disease (ESRD). …”
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New diagnostic approach to central hypothyroidism after traumatic brain injury in children and adolescents by Geraldo Miranda Graca, Luiz Roberto Aguiar, Luiz De Lacerda

“…Patients with CH received levothyroxine and progressed with clinical resolution and increased median fT4 (from 0.92 to 1.47 ng/dL) and IGF-1 (from −2.08 to −0.22 standard deviation scores (SDS)) levels. …”
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Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A by Mujahed I. Mustafa, Naseem S. Murshed, Abdelrahman H. Abdelmoneim, Miyssa I. Abdelmageed, Nafisa M. Elfadol, Abdelrafie M. Makhawi

“…It is the second most frequent type of HSP which is characterized by progressive bilateral and mostly symmetric spasticity and weakness of the legs. …”
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IL-6 variant is associated with metastasis in breast cancer patients. by Chike O Abana, Brian S Bingham, Ju Hwan Cho, Amy J Graves, Tatsuki Koyama, Robert T Pilarski, A Bapsi Chakravarthy, Fen Xia

“…Interleukin 6 (IL-6) has emerged as an important factor in breast cancer progression with IL-6 single nucleotide polymorphism (SNP) variants shown to affect survival. …”
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Exosome-Associated Gene Signature for Predicting the Prognosis of Ovarian Cancer Patients by Zihan Zhu, Rui Geng, Yixin Zhang, Jinhui Liu, Jianling Bai

“…The exosome is of vital importance throughout the entire progression of cancer. Because of the lack of effective biomarkers in ovarian cancer (OV), we intend to investigate the connection between exosomes and tumor immune microenvironment to verify that exosome-related genes (ERGs) can precisely forecast the prognosis of OV patients. …”
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Rib Spalling 3D Model for Soft Coal Seam Faces with Large Mining Height in Protective Seam Mining: Theoretical and Numerical Analyses by Shuai Liu, Ke Yang, Tong Zhang, Chunan Tang

“…Besides, a self-developed three-dimensional numerical calculation software RFPA3D (Realistic Fracture Process 3D Analysis), which considered the rock heterogeneity, was used to reproduce a weak triangular prism’s progressive failure process. The numerical simulation results agreed with the fracture pattern predicted by the theoretical model, which accurately described the rib spalling mechanisms in a soft coal face with a large cutting height and a protective layer.…”
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Characteristics of Patients with Newly Diagnosed Multiple Sclerosis – A 5-year Study at Benghazi Medical Center, Benghazi, Libya by Magda Elshukri, Kathloum Elkaseh, Anwaar Mukhtar Bennour, Heba Abdelrazek El-Zawawi

“…Research on regional MS should be improved and facilitated through the establishment of a Libyan MS registry, which will explore data about disease severity and/or progression and the response to treatment.…”
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Using the fuzzy cognitive map in designing a decision support system in diabetes insipidus by fatemeh haghani, alireza shahraki, Mohebali Rahdar

“…But with a faster and timely diagnosis, it can be prevented from progressing and the damage of lack of treatment, which can be irreparable. …”
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The boosting effect of minoxidil 0.1% when combined with dutasteride 0.01% and microneedling in the treatment of female pattern hair loss by Reham Essam, Heba Selim, Rana Ehab

“…Background Female pattern hair loss (FPHL) is a disease characterized by progressive hair thinning. Topical minoxidil is an FDA-approved drug for the treatment of androgenetic alopecia. …”
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Managing Post COVID-19 Patient with Breathlessness by Yen Shen Wong, Muhammad Amin Ibrahim, Mohd Arif Mohd Zim, Mohd Fauzi Abdul Rani

“…Multidisciplinary team discussion concluded it as interstitial pneumonia with COVID-19 OP and fibrosis progression. Prednisolone was stopped and he responded well with antibiotics. …”
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A Retrospective Claims-Based Study Evaluating Clinical and Economic Burden Among Patients With Moderate to Severe Osteoarthritis Pain in the United States by Patricia B. Schepman, Sheena Thakkar, Rebecca L. Robinson, Craig G. Beck, Deepa Malhotra, Birol Emir, Ryan N. Hansen

“…Assessing such longitudinal changes may be useful to patients and healthcare providers for tracking disease progression, informing treatment options, and employing strategies to optimize patient outcomes. …”
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Open Medial Meniscus Centralization With Arthroscopic Root Repair by Nicholas Newcomb MD, Jared Sanderford MD, Tyag Patel MD, Price Sessums MD, Ryan Price MD, William Curtis MD, Gehron Treme MD, Christopher Shultz MD

“…Results: Recent data have shown meniscal root repair with centralization is associated with significant improvements in pain, function, and quality of life and no significant progression of osteoarthritis. Discussion/Conclusion: Medial meniscal centralization can be safely performed with an open approach. …”
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Overcoming educational inequity for the urban poor through community-based schools: a case study of gajahwong school in Yogyakarta by Rahma Widyana, Bidta A. Hriday

“…Highlighting the urgency of inclusive and contextual education for children from poor urban communities, the school’s dynamic, contextual, and progressive curriculum is prepared for and based on the context of urban poor communities and children's rights, and is designed to meet children's needs and developmental characteristics. …”
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Experimental Study on Tunnel Failure Mechanism and the Effect of Combined Anti-Dislocation Measures Under Fault Dislocation by Jiaxuan Du, Songhong Yan, Weiyu Sun, Mingxing Cao, Yuxiang Li

“…The research focused on the cracking characteristics of the surrounding rock surface under the action of strike-slip faults, the progressive failure process of the tunnel model, and the mechanical response of the tunnel lining. …”
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Comparison of Amino Acid PET to Advanced and Emerging MRI Techniques for Neurooncology Imaging: A Systematic Review of the Recent Studies by Brittany M. Stopa, Csaba Juhász, Sandeep Mittal

“…Recent studies of aaPET with DWI showed a superiority of MET, FET, FDOPA, and AMT PET for detecting tumor, predicting recurrence, diagnosing progression, and predicting survival. Combining modalities further improved performance. …”
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Effects of the Layered Distribution Pattern on the Gas Flow Resistance through the Bed with the Multisize Irregular Particle for the Waste Heat Recovery by Sizong Zhang

“…Also, the effect of the layered distribution pattern on the gas flow resistance progressively weakens with increasing the equivalent particle diameter. …”
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Influences of AC/A ratio and accommodation facility on near vision in presbyopic individuals: A prospective study done on North Indian population by comparing the presbyopic glass... by Amit Kumar Jain, Suman Rajpoot, Vandana Batham, Praveen Kumar Singh, Neeraj Singh Rajput, Nirmala Rajput

“…Background: “Presbyopia” is the most common age-related condition of progressive loss of accommodative ability, typically occurs around the fourth decade of life. …”
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Electroacupuncture Regulates Macrophage Polarization to Alleviate the Neuropathic Pain Induced by Spared Nerve Injury by Shi G, Hao X, Tu JF, Chen W, Fu Y, Ma X, Liu C, Li H

“…The activation of macrophages and pro-inflammatory responses following peripheral nerve injury can effectively prevent the progression of neuropathic pain. Macrophage polarization to the M2 or M1 (respectively anti- and pro- inflammatory) phenotypes frequently occurs during neuroinflammation. …”
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