Potential of albumin dialysis at terminal liver failure in patients with chronic liver diseases by O. E. Nikiforova, Ye. N. Bessonova, O. M. Lesnyak, O. A. Stroganova

“…It is necessary to point, that in none patients MARS was complicated by bleeding or progression of other manifestations of hemorrhagic syndrome.Conclusions. …”
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LOX-induced tubulointerstitial fibrosis via the TGF-β/LOX/Snail axis in diabetic mice by Yicheng Lu, Heyangzi Li, Mohan Chen, Yicheng Lin, Xiaoming Zhang

“…However, the role of LOX in partial EMT and fibrotic progression in diabetic nephropathy has not been investigated experimentally. …”
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From ex vivo to in vivo chimeric antigen T cells manufacturing: new horizons for CAR T-cell based therapy by E. Pinto, L. Lione, M. Compagnone, M. Paccagnella, E. Salvatori, M. Greco, V. Frezza, E. Marra, L. Aurisicchio, G. Roscilli, A. Conforti

“…In this review, we highlight the challenges associated with the current ex vivo manufacturing protocols and review the latest progresses in the emerging field of in vivo CAR-T therapy, by comparing the various platforms so far investigated. …”
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Long non-coding RNA TINCR suppresses growth and epithelial-mesenchymal transition by inhibiting Wnt/β-catenin signaling pathway in human pancreatic cancer PANC-1 cells: Insights fr... by Wei Yuan, Zhu Ping

“…There is increasing evidence that long non-coding RNAs (lncRNAs) play a crucial role in the development and progression of malignant tumors, particularly pancreatic cancer. …”
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Microtrabeculectomy versus Conventional Trabeculectomy in Primary Open Angle Glaucoma: A Prospective Interventional Study by Rekha Ramesh Mudhol, Ameena Shirin

“…Introduction: Glaucoma is a group of multifactorial, irreversible, progressive optic neuropathies characterised by the loss of retinal ganglion cells. …”
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Relations Between Trunk Muscle Endurance, Stability, Balance Function, and Head Position in Adolescents with Idiopathic Scoliosis by Guoda Budrytė, Romualdas Sinkevičius, Lina Budrienė

“…In the case of idiopathic scoliosis, the interaction of these factors can influence the progression of scoliosis and the effectiveness of rehabilitation. …”
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Efficient Feature Selection and Hyperparameter Tuning for Improved Speech Signal-Based Parkinson’s Disease Diagnosis via Machine Learning Techniques by Deepak Painuli, Suyash Bhardwaj, Utku Kose

“… Parkinson’s disease (PD) is a neurodegenerative disorder that progressively worsens with age, particularly affecting the elderly. …”
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Atypical Hemolytic Uremic Syndrome after Traumatic Rectal Injury: A Case Report by Ji-Hyoun Kang, Donghyun Lee, Yunchul Park

“…Atypical hemolytic uremic syndrome (aHUS) is a rare, progressive, life-threatening condition of thrombotic microangiopathy characterized by thrombocytopenia, microangiopathic hemolytic anemia, and renal impairment. …”
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Prevalence and risk factors of the most common multimorbidity among Canadian adults. by Obed Mortey, Gerald Mugford, Kris Aubrey-Bassler, Hensley H Mariathas, Ugochukwu Odimba, Zhiwei Gao

“…The identification of the most prevalent patterns and associated risk factors in this study provides fresh insights into the etiology, progression, and possible prevention of the MCM among Canadian adults.…”
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KLF5 promotes esophageal squamous cell carcinoma radioresistance by targeting the Keap1-Nrf2 pathway by Yang Wang, Yue-ying Yang, Abulajiang Kamili, Dilimulati Aishanjiang, Yi Liu

“…They then injected ESCC cells into mice and used radiation to monitor tumor progression. Results KLF5 is a core gene in ESCC and is significantly associated with radiosensitivity. …”
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Central Diabetes Insipidus in Children and Adolescents: Twenty-Six Year Experience from a Single Centre by Hüseyin Anil Korkmaz, Ritika R Kapoor, Jennifer Kalitsi, Simon JB Aylwin, Charles R Buchanan, Ved Bhushan Arya

“…We affirm that neuroimaging assessment in idiopathic CDI should be continued beyond 3 years from diagnosis as a significant number of patients exhibited progression of infundibular thickening 3 years post-CDI diagnosis.…”
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Stachydrine targeting tumor-associated macrophages inhibit colorectal cancer liver metastasis by regulating the JAK2/STAT3 pathway by Yang Gui, Gengchen Xue, Yuyi Yuan, Jingbo Wang, Shuangjiao Deng, Fei Gao, Yushi Tian, Zhiqiang Zhao, Heng Fan

“…Moreover, the combination of STA with anti-PD-1 therapy has been observed to restore immune infiltration within the tumor microenvironment and inhibit tumor progression.ConclusionThe findings of this study demonstrate that STA exerts an inhibitory effect on colorectal cancer liver metastasis by targeting macrophages and impeding their M2 polarization via the JAK2/STAT3 pathway. …”
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Body mass index in relation to dental maturation of 10 to 14 years old school children in Erbil city. A cross-sectional prospective study by Omar Fawzi Chawshli, Yara Ismael Ameen

“… Background and Objectives: Estimation of dental age is based upon the rate of development and calcification of tooth buds and their progressive sequence of eruption in the oral cavity. …”
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Characterizing the Crosstalk of NCAPG with Tumor Microenvironment and Tumor Stemness in Stomach Adenocarcinoma by Zheng Xiang, Genlan Cha, Yihao Wang, Jikai Gao, Jianguang Jia

“…Nonstructural maintenance of non-SMC condensin I complex subunit G (NCAPG) exerts critical effects on cancer progression. However, its biological roles in tumorigenesis and metastasis remain unclear. …”
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Associations between the Global Diet Quality Score and risk of type 2 diabetes: Tehran lipid and glucose study. by Shahrzad Daei, Firoozeh Hosseini-Esfahani, Azam Ildarabadi, Parvin Mirmiran, Fereidoun Azizi

“…Multivariable Cox proportional hazards regression models were used to estimate the progression of T2D in association with the GDQS.<h4>Results</h4>This study was implemented on 2,688 men and 3,260 women, respectively with the mean (SD) age of 41.5(14.1) and 39.3(13.02) years. …”
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The imbalance of circulating PD-L1-expressing non-classical/ classical monocytes is involved in immunocompromised host related pulmonary opportunistic infection by Danhong Zhou, Yujia Jin, Yifan Jin, Yu Shen, Qiuxia Qu, Cheng Chen

“…Clinically, the lower ratio of PD-L1  +  cluster among CL subset ( P  < 0.05) and the less differentiated CL in PD-L1  +  monocytes ( P  < 0.05) was more likely to leaded to disease progression. The imbalance of circulating NC/CL subset was remarkable in immunocompromised host with pulmonary opportunistic infection, especially involvement of PD-L1 + cluster, which served as a potential biomarker in clinical practice.…”
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Thermo-mechanical response of aluminum alloy in the additive friction-stir deposition process by Chowdhury Sadid Alam, Vahid Karami, Shengmin Guo, M Shafiqur Rahman

“…Ultimately, this advancement contributes to the progression of solid-state AM techniques and development of digital twins by streamlining the process with scalability, multifunctionality, and a variety of material selections.…”
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The combined therapy of chronic hepatitis with pegilated interferon <i>a</i>-2а and ribavirin in patients with HIV-infection and patients with HCV monoinfection by N. D. Yuschuk, S. L. Maximov, L. M. Ivanova, Ye. K. Klimova, O. O. Znoyko, A. V. Kravchenko

“…During treatment significant decrease of CD4+ lymphocyte number took place, however no clinical signs of HIV-infection progression has been found.Conclusions. Antiviral therapy at combined HIV/CHC infection should be prescribed to all patients from the moment of establishment of diagnosis of chronic hepatitis while patients require no HAART. …”
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Clinicopathological and prognostic significance of the microcystic elongated and fragmented pattern in endometrial cancer: a systematic review and meta-analysis by Yan Zhang, Peng Jia, Baofeng Duan

“…Furthermore, aggregated data revealed a linkage between the MELF pattern and significant MI, nodal metastasis, involvement of the lymphovascular space, penetration of the cervical stroma and progression to advanced stages of endometrial carcinoma.Conclusion The MELF pattern serves as a significant adverse prognostic factor in endometrial cancer, warranting increased attention.…”
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Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption. by Lauren A Hirao, Irina Grishina, Olivier Bourry, William K Hu, Monsicha Somrit, Sumathi Sankaran-Walters, Chris A Gaulke, Anne N Fenton, Jay A Li, Robert W Crawford, Frank Chuang, Ross Tarara, Maria L Marco, Andreas J Bäumler, Holland Cheng, Satya Dandekar

“…Breakdown in gut barrier integrity is linked to chronic inflammation and disease progression. However, the early effects of HIV on the gut epithelium, prior to the CD4+ T cell depletion, are not known. …”
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