Assessing routine childhood vaccination acceptance, hesitancy and refusal in Cape Town, Western Cape, South Africa: a mixed-method study protocol by Charles Shey Wiysonge, Lindi Mathebula, Moleen Zunza, Sara Cooper

“…Since the introduction of the Expanded Programme on Immunisation worldwide by WHO in 1974, vaccines have saved more than 150 million lives and prevented countless illnesses and disabilities. …”
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Enhanced Recovery after Intensive Care (ERIC): study protocol for a German stepped wedge cluster randomised controlled trial to evaluate the effectiveness of a critical care telehe... by Ulrich Mansmann, Claudia Spies, Ursula Marschall, Reinhard Busse, Christine Adrion, Bjoern Weiss, Nicolas Paul, Elke Berger, Jörg Caumanns, Simone Rosseau

“…After a multifactorial training programme on QIs and clinical outcomes for site personnel, ICUs will receive an adapted, interprofessional protocol for a complex telehealth intervention comprising of daily telemedical rounds at ICU. …”
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Physical Activity, Fatigue, and Sleep in People with Parkinson’s Disease: A Secondary per Protocol Analysis from an Intervention Trial by S. Coe, M. Franssen, J. Collett, D. Boyle, A. Meaney, R. Chantry, P. Esser, H. Izadi, H. Dawes

“…PwP randomised into either an exercise group (29; 16 males, 13 females; mean age 67 years (7.12)) or a control handwriting group (36; 19 males; 17 females; mean age 67 years (5.88)) as part of a larger trial were included in this substudy if they had completed a 6-month weekly exercise programme (intervention group) and had complete objective physical activity data (intervention and control group). …”
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The Global RAdical Cystectomy Evaluation and Management (GRACEM) pathway: single‐centre prospective observational cohort study protocol by Bruno Bernardini, Federico Piccioni, Manuele Pastore, Paolo Casale, NicolòMaria Buffi, Giovanni Lughezzani, Massimo Lazzeri, Alberto Saita, Maria Vittoria Fantacci, Stefano Mancon, Filipo Dagnino, Roberto Contieri, Pietro Brin, Stefano Mancin, Andrea Gobbo, Maria Rosaria Martucci, Giovanna Cerina, Sara Ghirmai, Ezio Lanza, Giulia Goretti, Giorgio Ferruccio Guazzoni, Rodolfoi Hurle

“…The purpose of the study is to determine whether a multifaceted prevention programme that tailors interventions to the syndromic components of frailty can improve postoperative morbidity and recovery time for patients. …”
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Effects of cardiovascular health, musculoskeletal health and physical fitness on occupational performance of firefighters: protocol for a systematic review and meta-analysis by Andre Pascal Kengne, Denise Smith, Jaron Ras, Elpidoforos Soterakis Soteriades, Lloyd Leach

“…The The appraisal tool for cross-sectional studies (AXIS) checklist and the Critical Appraisal Skills Programme toolkit will be used to conduct the methodological assessment of each study. …”
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Gastric cancer incidence, mortality and burden in adolescents and young adults: a time-trend analysis and comparison among China, South Korea, Japan and the USA by Jian Li, Yao Zhang, Si Lin Wu, Yi Fu, Ji Sheng Wang

“…The MIRs declined constantly in South Korea and China, and the MIR in the USA became the highest in 2019.Conclusions Although not covered by prevention and screening programmes, variations in disease burden and time trends may reflect variations in risk factors, cancer control strategies and treatment accessibility of GC among the four countries. …”
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Interpretation of indoor air surveillance for respiratory infections: a prospective longitudinal observational study in a childcare settingResearch in context by Caspar Geenen, Steven Traets, Sarah Gorissen, Michiel Happaerts, Kurt Beuselinck, Lies Laenen, Jens Swinnen, Sien Ombelet, Joren Raymenants, Els Keyaerts, Emmanuel André

“…Funding: KU Leuven; DURABLE project, under the EU4Health Programme of the European Commission; Thermo Fisher Scientific.…”
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Insights from a codesigned dynamic modelling study of child and adolescent obesity in Australia by Alison Hayes, Rebecca Wyse, Anna Lene Seidler, Kylie E Hunter, Rebecca K Golley, Louise A Baur, Anthony D Okely, Kenny Lawson, Jo-An Occhipinti, Louise Freebairn, Simon Keith Chiu, Joseph Carrello, L Kurt Kreuger

“…Insights from the model emphasise the value of public health programmes over the life course. Implementing initiatives with broad reach that support healthy choices may reduce obesity, resulting in a healthier Australian population.…”
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Cost of introducing and delivering malaria vaccine (RTS,S/AS01E) in areas of seasonal malaria transmission, Mali and Burkina Faso by Jean Bosco Ouédraogo, Alassane Dicko, Ranju Baral, Clint Pecenka, Halimatou Diawara, Fadima Yaya Bocoum, Ann Levin, Cynthia Lee, Fatoumata Koita, Rosemonde Guissou, Seydou Yabré, Seydou Traoré, Winthrop Morgan

“…This study prospectively estimates cost of seasonal malaria vaccine delivery in Mali and Burkina Faso.Methods Three scenarios for seasonal vaccine delivery are costed (1) mass campaign only, (2) routine Expanded Programme on Immunisation (EPI) and (3) mixed delivery (mass campaign and routine EPI)), from the government’s perspective. …”
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Ten years preceding a diagnosis of neurodegenerative disease in Europe and Australia: medication use, health conditions, and biomarkers associated with Alzheimer's disease, Parkins... by Dang Wei, Anna Freydenzon, Octave Guinebretiere, Karim Zaidi, Fen Yang, Weimin Ye, Niklas Hammar, Karin Modig, Naomi R. Wray, Maria Feychting, Nadine Hamieh, Bruno Ventelou, Beranger Lekens, Laurene Gantzer, Stanley Durrleman, Allan McRae, Baptiste Couvy-Duchesne, Fang Fang, Thomas Nedelec, Stanley Durrleman, Bruno Ventelou, Thomas Nedelec, Octave Guinebretiere, Karim Zaidi, Fang Fang, Dang Wei, Fen Yang, Allan McRae, Naomi Wray, Baptiste Couvy-Duchesne, Anna Freydenzon, Lydie Tran, Evans Cheruiyot

“…Conversely, the increased prevalence of constipation is specific to AD and PD, while the decreased prevalence of diabetes and use of antidiabetics is specific to ALS. Funding: EU Joint Programme—Neurodegenerative Disease Research.…”
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Does a complex intervention targeting communities, health facilities and district health managers increase the utilisation of community-based child health services? A before and af... by Joanna Schellenberg, Della Berhanu, Lars Åke Persson, Muluemebet Abera Wordofa, Araya Abrha Medhanyie, Fisseha Ashebir Gebregizabher, Habtamu Beyene, Ephrem Tekle Lemango, Abebe Bekele, Theodros Getachew, Mezgebu Yitayal, Yemisrach Behailu Okwaraji, Atkure Defar, Fitsum W/Gebriel, Alem Desta, Dawit Wolde Daka, Alemayehu Hunduma, Tigist Getahun, Amare Tariku Woldemariam, Desta Wolassa

“…Optimising the Health Extension Programme was a 2-year intervention in 26 districts, focusing on community engagement, capacity strengthening of primary care workers and reinforcement of district accountability of child health services. …”
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Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…The aim was therefore to investigate the feasibility of delivering exercise-based cardiac rehabilitation for patients with AF receiving catheter ablation within usual care in the UK.Methods and analysis A two-armed feasibility RCT with embedded process evaluation will be undertaken as a phased programme of work. Patients on a waiting list for catheter ablation will be offered a referral to cardiac rehabilitation. …”
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Effectiveness of a Positive Youth Development Program for Secondary 1 Students in Macau: A Pilot Study by Andrew L. Luk, Annah M. L. Au, K. M. Leong, Michelle M. X. Zhu, G. B. Lau, Tammy C. P. Wong, Nancy W. I. Lei

“…(Positive Adolescent Training through Holistic Social Programmes), which was adopted and modified for Macau. …”
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Evaluation of the Sterile Insect Technique for the Control of the Melon Fly (<i>Bactrocera cucurbitae</i>) Under Laboratory and Semi-Field Conditions in Sri Lanka by Muditha Nawarathne, Lahiru Udayanga, Hasini Ekanayake, Bader Alhafi Alotaib, Ananda Pathirage, Nayana Siriwardena, Athula Jayarathne, Hassan Ammouneh, Mohamed M. M. Najim, Abou Traore, Tharaka Ranathunge

“…The 70 Gy dose could be recommended as the optimal radiation dose for the production of sterile <i>B. cucurbitae</i> males with an acceptable level of fitness and sterility to be used in SIT-based melon fly control programmes in Sri Lanka.…”
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Spatial and temporal epidemiology of SARS-CoV-2 virus lineages in Teesside, UK, in 2020: effects of socio-economic deprivation, weather, and lockdown on lineage dynamics by Moss, E.D., Rushton, S.P., Baker, P., Bashton, M., Crown, M.R., dos Santos, R.N., Nelson, A., O’Brien, S.J., Richards, Z., Sanderson, R.A., Yew, W.C., Young, G.R., McCann, C.M., Smith, D.L.

“…As the outbreak continued, new variants were detected through two national monitoring programmes that conducted genomic sequencing. This study aimed to determine the effects of weather, demographic features, and national and local COVID-19 restrictions on positive PCR tests at a sub-regional scale. …”
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A novel pulse-current waveform circuit for low-energy consumption and low-noise transcranial magnetic stimulation by Xinhua Tan, Ao Guo, Jiasheng Tian, Yingwei Li, Yingwei Li, Jian Shi

“…Next, the pulse-current waveform was modeled based on the principles of programmable transcranial magnetic stimulation circuits. …”
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Best practice portals in health promotion and disease prevention: approaches, definitions, and intervention evaluation criteria by Maria Piotrowicz, Małgorzata Gajewska, Katarzyna Lewtak, Katarzyna Lewtak, Ewa Urban, Anna Rutyna, Aneta Nitsch-Osuch

“…Best practice portals (BPPs) are promising tools for facilitating access to recommended programmes, monitoring and improving the quality of interventions. …”
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Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey by Christi Deaton, Robin Fox, Ian Wellwood, Carolyn Chew-Graham, Katherine Brown, Sharon Dixon, Thomas Blakeman, Alistair Brown, Julie Smith, Nick Thomas, Adam Jones, Basilio Hernandez-Diaz, Christopher Keast, Heather Rutter, Kyle Knox, Matthew Gaw, Nick Wooding, Christine A'Court, Hannah Swayze, Helen Ashdown, Victoria Glover, Rosalynn Austin, Eva Khair, Muhammad Zakir Hossain, Emma Sowden, Faye Forsyth, Mollika Chakravorty, Sophie Maclachlan, Edward Kane, Jessica Odone, Natasha Thorley, Susana Borja-Boluda, Muhammed Hossain, John Sharpley, Brain Gordon, Joanna Taffe, Aaron Long, Affan Aziz, Chris Schramm, Sine MacDonald, Helena Papworth, Craig Needs, David Cronk, Chris Newark, Duncan Blake, Amman Basuita, Emma Gayton, Jonathan Crawshaw, Rachael Ayerst, Shamila Wanninayake, Elisabetta Angeleri-Rand

“…The survey aim was to examine consensus between primary and secondary care providers regarding HFpEF diagnosis and management.Methods As part of a larger programme of work, survey questions were developed in an online format and piloted with healthcare providers (HCPs). …”
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Intensive home visiting for adolescent mothers in the Family Nurse Partnership in England 2010–2019: a population-based data linkage cohort study using propensity score matching by Ruth Gilbert, Jan van der Meulen, Katie Harron, Eilis Kennedy, Sally Kendall, Francesca Cavallaro

“…Background We evaluated the effectiveness of the Family Nurse Partnership (FNP), an intensive home visiting programme aiming to improve birth outcomes, child health and development, and to promote economic self-sufficiency among teenage mothers.Methods We created a linked cohort of &gt;130 000 mothers aged 13–19 years with live births between April 2010 and March 2019, using administrative data from health (Hospital Episode Statistics), education and children’s social care (National Pupil Database). …”
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Hybrid versus vaccine immunity of mRNA-1273 among people living with HIV in East and Southern Africa: a prospective cohort analysis from the multicentre CoVPN 3008 (Ubuntu) studyRe... by Nigel Garrett, Asa Tapley, Aaron Hudson, Sufia Dadabhai, Bo Zhang, Nyaradzo M. Mgodi, Jessica Andriesen, Azwidihwi Takalani, Leigh H. Fisher, Jia Jin Kee, Craig A. Magaret, Manuel Villaran, John Hural, Erica Andersen-Nissen, Guido Ferarri, Maurine D. Miner, Bert Le Roux, Eduan Wilkinson, Richard Lessells, Tulio de Oliveira, Jackline Odhiambo, Parth Shah, Laura Polakowski, Margaret Yacovone, Taraz Samandari, Zvavahera Chirenje, Peter James Elyanu, Joseph Makhema, Ethel Kamuti, Harriet Nuwagaba-Biribonwoha, Sharlaa Badal-Faesen, William Brumskine, Soritha Coetzer, Rodney Dawson, Sinead Delany-Moretlwe, Andreas Henri Diacon, Samantha Fry, Katherine Margaret Gill, Zaheer Ahmed Ebrahim Hoosain, Mina C. Hosseinipour, Mubiana Inambao, Craig Innes, Steve Innes, Dishiki Kalonji, Margaret Kasaro, Priya Kassim, Noel Kayange, William Kilembe, Fatima Laher, Moelo Malahleha, Vongane Louisa Maluleke, Grace Mboya, Kirsten McHarry, Essack Mitha, Kathryn Mngadi, Pamela Mda, Tumelo Moloantoa, Cissy Kityo Mutuluuza, Nivashnee Naicker, Vimla Naicker, Anusha Nana, Annet Nanvubya, Maphoshane Nchabeleng, Walter Otieno, Elsje Louise Potgieter, Disebo Potloane, Zelda Punt, Jamil Said, Yashna Singh, Mohammed Siddique Tayob, Yacoob Vahed, Deo Ogema Wabwire, M. Juliana McElrath, James G. Kublin, Linda-Gail Bekker, Peter B. Gilbert, Lawrence Corey, Glenda E. Gray, Yunda Huang, Philip Kotze, Sharlaa Badal-Faesen, Kagisho Baepanye, Veronique Bailey, Katekani Baloyi-Oseh, Mumtaz Booley, Johannes Louis Botha, Yolande Brown, Valerie Brown, Lisa Bunts, Soritha Coetzer, Myron Cohen, Shirley Collie, Rodney Dawson, Pallabi Deb, Hana El Sahly, Jill El-Khorazaty, Andries Engelbrecht, Marianne Gildea, Dhevium Govender, Jen Hanke, Jayla Harris, Simone Hendricks, Nick Hopkinson, Haley Howell, Nzeera Ketter, Kentse Khuto, Faatima Laher Omar, Leolin Katsidzira, Kim Linton, James Ludwig, Bongile Mabilane, Matshidiso Malefo, Ndiitwani Mamushiana, Daciana Margineantu, Jeanine May, Fatima Mayat, Cindy Molitor, Yeshnee Naidoo, Michelle Nebergall, Alan Nguyen, Sarah Nikles, Bianca Noronha, Melissa Peda, Tamara Phiri, Shanthie Pillay, Sureshnee Pillay, Lori Proulx-Burns, Laurie Rinn, Lisa Sanders, Carrie Sopher, Smitha Sripathy, Michael Stirewalt, Houriiyah Tegally, Sara Thiebaud, Alicia Toledano, Stephanie Van Wyk, Shamaya Whitby, Stephany Wilcox, Eduan Wilkinson, Haven Wilvich, Charles Wiysonge, Nelisiwe Xaba, Ntokozo Xulu

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