Mycobacteria Exploit Host GPR84 to Dampen Pro-Inflammatory Responses and Promote Infection in Macrophages by Reziya Wumaier, Ke Zhang, Jing Zhou, Zilu Wen, Zihan Chen, Geyang Luo, Hao Wang, Juliang Qin, Bing Du, Hua Ren, Yanzheng Song, Qian Gao, Bo Yan

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Exosomal Hsp70 induces a pro-inflammatory response to foreign particles including mycobacteria. by Paras K Anand, Ellis Anand, Christopher K E Bleck, Elsa Anes, Gareth Griffiths

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Systemic pro-inflammatory response following bronchoscopic lung volume reduction using endobronchial valves by Jorine E. Hartman, Marieke C. van der Molen, Marnix R. Jonker, Rein Posthuma, Lowie E.G.W. Vanfleteren, Dirk-Jan Slebos, Simon D. Pouwels

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N-acetylaspartate mitigates pro-inflammatory responses in microglial cells by intersecting lipid metabolism and acetylation processes by Federica Felice, Pamela De Falco, Martina Milani, Serena Castelli, Antonella Ragnini-Wilson, Giacomo Lazzarino, Nadia D’Ambrosi, Fabio Ciccarone, Maria Rosa Ciriolo

“…The effects on the pro-inflammatory response were evaluated by analysis of protein/mRNA expression and ChIP assay of typical inflammatory markers. …”
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Top-down generated micro- and nanoplastics reduce macrophage viability without eliciting a pro-inflammatory response by Annemijne E. T. van den Berg, Kas J. Adriaans, Luke A. Parker, Elena M. Höppener, Hanna M. Dusza, Juliette Legler, Raymond H.H. Pieters

“…Our findings suggest a lack of a direct pro-inflammatory response by macrophages to fragmented MNPs of various polymer types. …”
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Bacterial and host enzymes modulate the pro-inflammatory response elicited by the peptidoglycan of Lyme disease agent Borrelia burgdorferi. by Joshua W McCausland, Zachary A Kloos, Irnov Irnov, Nicole D Sonnert, Junhui Zhou, Rachel Putnik, Elizabeth A Mueller, Allen C Steere, Noah W Palm, Catherine L Grimes, Christine Jacobs-Wagner

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Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma by Juanfen Mo, YuXuan Zhang, Chenxi Cao, WeiLi Zheng, Li Zheng, Xiaoguang Wang, Shiyue Wang, Jiayuan Wu, Yi Bao

“…Furthermore, Piezo1 channel activation by its agonist mediated pro-inflammatory responses mainly through its downstream molecule CXCL8 via ERK1/2 and AKT signaling pathways by up-regulating CXCL8 expression in transcriptional levels of HCC cells. …”
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CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses. by Sallieu Jalloh, Judith Olejnik, Jacob Berrigan, Annuurun Nisa, Ellen L Suder, Hisashi Akiyama, Maohua Lei, Sita Ramaswamy, Sanjay Tyagi, Yuri Bushkin, Elke Mühlberger, Suryaram Gummuluru

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MicroRNA exporter HuR clears the internalized pathogens by promoting pro‐inflammatory response in infected macrophages by Avijit Goswami, Kamalika Mukherjee, Anup Mazumder, Satarupa Ganguly, Ishita Mukherjee, Saikat Chakrabarti, Syamal Roy, Shyam Sundar, Krishnananda Chattopadhyay, Suvendra N Bhattacharyya

“…Here we have identified how HuR, by inducing extracellular vesicles‐mediated export of miRNAs, ensures robust derepression of miRNA‐repressed cytokines essential for strong pro‐inflammatory response in activated mammalian macrophages. …”
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Cadmium decreases human gingival fibroblast viability and induces pro-inflammatory response associated with Akt and MAPK pathway activation by Tipparat Parakaw, Sirada Srihirun, Nathawut Sibmooh, Nisarat Ruangsawasdi, Phisit Khemawoot, Pornpun Vivithanaporn

“…Smoking and particulate matter 2.5 (PM2.5) expose millions to cadmium (Cd), a toxic heavy metal linked to pro-inflammatory responses, oxidative stress, and disease pathogenesis. …”
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Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-γ-treated macrophages to Pseudomonas aeruginosa infection. by Sonali Singh, Helen Barr, Yi-Chia Liu, Adrian Robins, Stephan Heeb, Paul Williams, Andrew Fogarty, Miguel Cámara, Luisa Martínez-Pomares

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IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes by Lei Bao, Christian F. Guerrero-Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu, Adrian P. Mansini, Yulu F. Wang, Aadil Ahmed, Norito Ishii, Takashi Hashimoto, Bethany E. Perez White, Stefan Green, Kevin Kunstman, Nicole C. Nowak, Connor Cole, Mrinal K. Sarkar, Johann E. Gudjonsson, Macias Virgilia, Maria Sverdlov, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Enno Schmidt, Kyle T. Amber

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SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

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MicroRNA-22 Regulates the Pro-inflammatory Responses and M1 Polarization of Macrophages by Targeting GLUT1 and 4-1BBL by Young Jun Kang

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The short peptide encoded by long non-coding RNA RNF217-AS1 inhibits stomach cancer tumorigenesis, macrophage recruitment, and pro-inflammatory responses by Qi Ma, Fei Ma, Bin Zhang, Yonglei Zhang, Liangqun Peng, Xiangnan Li

“…As a conclusion, the RNF217-AS1 ORF-encoded peptide hindered SC progression in vitro and in vivo and suppressed macrophage recruitment and pro-inflammatory responses in SC.…”
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TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans. by Mufadhal Al-Kuhlani, James Rothschild, Sukumar Pal, Luis M de la Maza, Sander Ouburg, Servaas A Morré, Deborah Dean, David M Ojcius

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A humanized anti-Toll like receptor 4 antibody Fab fragment inhibits pro-inflammatory responses induced by lipopolysaccharide through TLR4 in vitro and in vivo by Wenkai Zheng, Fang Xie, Shuping Si, Xi Xiong, Jing Xu, Chuanxia Yao, Cong Li, Jin Zhu, Ping Li, Binggang Cai, Maorong Wang

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Complement and Coagulation Cascade Activation Regulates the Early Inflammatory Mechanism of Resistance of Suckling Lambs Against <i>Haemonchus contortus</i> by José Gabriel G. Lins, Alessandro F. T. Amarante

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Toxicity enhancement of microplastics released from food containers through thermal aging: Absorbing more serum proteins thus activating the innate immune response via actin polyme... by Fang Du, Meiqian Hou, Song Lu, Xiaotian Ding, Ling Zhang, Yajie Du, Zhen An, Wenwen Cai, Leicheng Zhao, Weidong Wu, Zhiguo Cao

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Phytochemicals Targeting Inflammatory Pathways in Alcohol-Induced Liver Disease: A Mechanistic Review by Swati Tirunal Achary, Prerna Gupta, Apoorva Rajput, Wanphidabet Sohkhia, Srinivasa Reddy Bonam, Bidya Dhar Sahu

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