Cardiovascular outcomes associated with treatment of type 2 diabetes in patients with ischaemic heart failure by Thomas R. Godec, Daniel I. Bromage, Mar Pujades‐Rodriguez, Antonio Cannatà, Arturo Gonzalez‐Izquierdo, Spiros Denaxas, Harry Hemingway, Ajay M. Shah, Derek M. Yellon, Theresa A. McDonagh

“…Methods and results This study used linked data from primary care, hospital admissions, and death registries for 4.7 million inhabitants in England, as part of the CALIBER resource. …”
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Seroprevalence against SARS-CoV-2 after booster vaccination in a prison in Alicante (Spain) by Ana C. Montagud, Raul Moragues, Nancy Vicente-Alcalde, Nancy Vicente-Alcalde, Emilia Montagud, José Antonio Hurtado-Sánchez, José Antonio Hurtado-Sánchez, José Tuells, José Tuells

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INdependenT prEscribinG in community phaRmAcy; whaT works for whom, why and in what circumstancEs (INTEGRATE): Realist review study protocol [version 1; peer review: 2 approved] by Andrew Sturrock, Tony Kelly, Vivienne Hibberd, Ian Maidment, Ola Amr Abdelfatah, Nia Roberts, Ellen Schafheutle, Andrea Hilton, Keith Holden, Geof Wong, Nick Haddington, Lesley Scott

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Implementing and evaluating the comprehensive integration of physical activity into a major health system: study design and protocol by Alex Ewing, Mark Stoutenberg, Jennifer L Trilk, Christopher Wichman, Paul A Estabrooks, John M Brooks, Meenu Jindal, James Rosemeyer, Leah M Schumacher, Lia K McNulty, Stephanie Eskuri, Frankie Bennett

“…Since inception, variability has emerged in adoption and implementation, impacting patient reach, referral rates and engagement in the community-based PA programmes, highlighting the need for closer evaluation and refinement of strategies to maximise programme impact.Methods and analysis This pragmatic study will examine the adoption, implementation and reach of EIMG. 20 Prisma Health primary care clinics will be invited to adopt EIMG. In Phase I, adopting clinics will receive a standardised EIMG instructional video followed by EIMG activation, allowing providers to refer eligible patients to a 12-week evidence-informed PA programme offered at local community facilities. …”
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Sangre Por Salud (SPS) Biobank: cohort profile by Richard R Sharp, Euijung Ryu, Janet E Olson, Karen Meagher, James R Cerhan, Davinder Singh, Suzette Bielinski, Emmil Zarrugh, Marlene E Girardo, Giovanna Moreno Garzon, Valentina Hernandez, Sharon Levey, Crystal Gonzalez, Daniela B Pompa, Gabriel Q Shaibi, Lawrence Mandarino, Steven Thibodeau, Elena De Filippis

“…Purpose The Sangre Por Salud (SPS) Biobank was established to facilitate biomedical research opportunities for the Latino community by creating an easily accessible prospective cohort for scientists interested in studying health conditions and health disparities in this population.Participants Individuals self-identifying as Latino, aged 18–85 years, were prospectively recruited from the primary care Internal Medicine clinic at Mountain Park Health Center in Phoenix, Arizona. …”
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ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

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Cohort profile: the Western Cape Pregnancy Exposure Registry (WCPER) by Landon Myer, Amy L Slogrove, Ushma Mehta, Mary-Ann Davies, Max Kroon, Greg Petro, Alexa Heekes, Andrew Boulle, Karen Fieggen, Chantal Stewart, Ayesha Osman, Natasha Rhoda, Emma Kalk, Florence Phelanyane, Jonathan Euvrard, Stefan Gebhardt, Kim Anderson

“…Purpose The Western Cape Pregnancy Exposure Registry (PER) was established at two public sector healthcare sentinel sites in the Western Cape province, South Africa, to provide ongoing surveillance of drug exposures in pregnancy and associations with pregnancy outcomes.Participants Established in 2016, all women attending their first antenatal visit at primary care obstetric facilities were enrolled and followed to pregnancy outcome regardless of the site (ie, primary, secondary, tertiary facility). …”
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Effectiveness of multicomponent interventions in primary healthcare settings to promote continuous smoking cessation in adults: a systematic review by Carlos Martín Cantera, Elisa Puigdomènech, Jose Luis Ballvé, Olga Lucía Arias, Lourdes Clemente, Ramon Casas, Lydia Roig, Santiago Pérez-Tortosa, Laura Díaz-Gete, Sílvia Granollers

“…Objective The objective of the present review is to evaluate multicomponent/complex primary care (PC) interventions for their effectiveness in continuous smoking abstinence by adult smokers.Design A systematic review of randomised and non-randomised controlled trials was undertaken.Eligibility criteria for included studies Selected studies met the following criteria: evaluated effects of a multicomponent/complex intervention (with 2 or more intervention components) in achieving at least 6-month abstinence in adult smokers who visited a PC, biochemical confirmation of abstinence, intention-to-treat analysis and results published in English/Spanish.Methods We followed PRISMA statement to report the review. …”
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Factors associated with early childhood development: results from the Brazilian National Survey on Child Nutrition (ENANI-2019) by Gilberto Kac, Nadya Helena Alves-Santos, Dayana Rodrigues Farias, Nathalia Cristina Freitas-Costa, Raquel Scincaglia, Paula Normando, Inês Rugani, Elisa Maria de Aquino Lacerda, Sandra Crispim, Alexandra Valeria Maria Brentani, Claudia Regina Lindgren Alves

“…For children aged 36–59 months, attendance to private daycare/school (β=0.08; p<0.01) was positively associated with DQ, and small for gestational age at birth (β=−0.05; p=0.01) and access to public health services (no-primary care) (β=−0.07; p<0.01) were inversely associated with DQ.Conclusions Adverse health, nutrition and learning factors predicted the ECD, demonstrating an inequitable environment for Brazilian children. …”
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Evaluation of parent reminder-recall letters to promote human papillomavirus vaccination by Joan M. Griffin, Xuan Zhu, Wei Yi Kong, Robert M. Jacobson, Kathy L. MacLaughlin, Jennifer L. St. Sauver, Jeph Herrin, Gregory D. Jenkins, Nicole L. Larson, Lila J. Finney Rutten

“…Methods: This cross-sectional evaluation included data from parents (n = 1165) of adolescents ages 11–12 from six primary care practices who received letters about their child's HPV vaccination status. …”
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MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of... by Andrew Clegg, James Wason, Miles Witham, Nina Wilson, Claire J Steves, Helen C Hancock, Avan A P Sayer, Leanne Marsay, Claire McDonald, Thomas von Zglinicki, Katherine J Rennie, Penny Bradley, Stephen Connolly, Shaun Hiu, Laura Robertson, Laura Simms, Alison J Steel, Bryony Storey

“…The recruitment target is 80 participants from two secondary care hospitals in Newcastle and Gateshead, UK. Local primary care practices will act as participant identification centres. …”
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Health-Related Quality of Life in Long COVID: Mapping the Condition-Specific C19-YRSm Measure Onto the EQ-5D-5L by Smith AB, Greenwood DC, Williams P, Kwon J, Petrou S, Horton M, Osborne T, Milne R, Sivan M

“…Adam B Smith,1 Darren C Greenwood,1,2 Paul Williams,3 Joseph Kwon,4 Stavros Petrou,4 Mike Horton,5 Thomas Osborne,5 Ruairidh Milne,6 Manoj Sivan5,7,8 On behalf of LOCOMOTION Consortium1Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom; 2Leeds Institute for Data Analytics, University of Leeds, Leeds, UK; 3COVID Assessment and Rehabilitation Service, Hertfordshire Community NHS Trust, Welwyn Garden City, UK; 4Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK; 5Academic Department of Rehabilitation Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; 6Person with Long COVID; Public Health, University of Southampton, Southampton, UK; 7COVID Rehabilitation Service, Leeds Community Healthcare NHS Trust, Leeds, UK; 8National Demonstration Centre of Rehabilitation Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UKCorrespondence: Adam B Smith, Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom, Email a.b.smith@leeds.ac.ukBackground: Long COVID (LC) is a clinical syndrome with persistent, fluctuating symptoms subsequent to COVID-19 infection. …”
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Kidney failure-related excess mortality during the first three years of the COVID-19 pandemic in the United States: a nation-wide, population-based analysis by Zhenhu Chen, Pingping Jia, Di Xie, Jingyu Xie, Juan Liu, Wangnan Cao, Lefei Han, Jinjun Ran, Shengzhi Sun, Shi Zhao, Yang Ge, Leonardo Martinez, Xin Chen, Peihua Cao

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Point-of-care tests in the emergency medical services: a scoping review by T. H. M. Moore, S. Dawson, K. Kirby, R. Body, A. Thompson, Y. O. Adepoju, R. Perry, H. Nicholson, J. Dinnes, K. Mitchell, J. Savović, S. Voss, J. R. Benger

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Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

“…Incident all-cause dementia cases were obtained from national hospital admission, primary care and mortality data followed up to 30 November 2022. …”
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Holistic health and social care outreach for people experiencing homelessness with recent non-fatal overdose in Glasgow, Scotland: the Pharmacist and third sector Homeless charity... by Vibhu Paudyal, Nicola Greenlaw, Frances S Mair, Kate Stock, Andrew McPherson, Andrea E Williamson, Richard Lowrie, Donogh Maguire, Steven Ross, James Roy Robertson, Alison Boyle, Clare Duncan, Rebecca Blair, Cian Lombard, Fiona Hughes, Jane Moir, Ailsa Scott, Frank Reilly, Laura Sills, Jennifer Hislop, Stephen Wishart, David Brannan, Rebekah Ramage

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Patient-centred care and quality of life and hope among Japanese patients receiving home medical care: a multicentre, cross-sectional study by Nobuhiro Ikeda, Michiko Hinata, Noriaki Kurita, Tomoka Nakamura, Takashi Fujii, Chihiro Tsuchiya, Yukio Tsugihashi, Hidekazu Iida, Shinu Hayashi, Masakazu Yasunaka, Misaki Hirose, Yutaka Shirahige, Shinsuke Muto, Tatsunobu Natsubori, Wataru Nakagawa, Akihiko Yonenaga, Lina Inagaki, Shioto Itakura, Naoya Miyashita, Takuya Furugen, Takafumi Abo, Sadayuki Okudaira, Kazuhiko Takuma, Masahiro Deguchi, Yoshitaka Harada, Seiji Matsuo, Motomichi Nakagawa, Ken Tanigawa, Yoshio Ochi, Sadanobu Ogasawara, Kazuhiko Hoshino, Momoko Aruga, Yoshinori Nakamura, Nobuhiro Sawa, Yosuke Akashi, Nobuyuki Miyagi, Toyohiro Terasaki, Kunihiro Kinoshita, Masaji Kikukawa, Hisakazu Kato, Masayuki Amano, Kentaro Asakura, Naoto Fukui

“…This study examined the association between the quality of patient-centred care and both QOL and hope.Design Multicentre, cross-sectional study.Setting Twenty-nine home care clinics in the Tokyo Metropolitan Area, Nara Prefecture and Nagasaki Prefecture in Japan.Participants 200 patients receiving home medical care.Exposure Patient-centredness was measured using the Japanese version of the Primary Care Assessment Tool-Short Form (JPCAT-SF).Outcome measures The primary outcome measures were QOL, assessed using the QOL-Home Care (QOL-HC) scale, and hope, measured using the Health-Related Hope (HR-Hope) scale. …”
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The contextual adaptation and educational impacts of the mhGAP-IG to address child mental and behavioral disorder treatment gap in China: A mixed-method study by Meng Zheng, Yi Zhang, Feng Chen, Ang Chen, Di Kong, Kun Xie, Jie Li, Brian James Hall, Andre M.N. Renzaho, Jian-hui Gao, Dao-meng Cheng, Qing Zou, Xin-yuan Zhong, Qi-mei Yu, Wen Chen

“…Qualitative data were collected via key informant interviews with six mental health experts and two focus group discussions involving seven kindergarten teachers or doctors and six general practitioners (GPs) from primary care centers. A qualitative analysis utilizing deductive and inductive thematic coding was applied. …”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

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Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care... by Richard D Neal, Kevin Franks, David Torgerson, Rachael L Murray, David R Baldwin, Michael Darby, Henrik Moller, Richard Booton, Una MacLeod, Sam M Janes, Samantha L Quaife, Sebastian Hinde, Matthew EJ Callister, Suzanne Rogerson, Rhian Gabe, Mark Sculpher, Philip AJ Crosbie, Irene Simmonds, Martyn Kennedy, Nazia Ahmed, Ann Cochrane, Mike Messenger, Puvanendran Tharmanathan

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