Impact of the COVID-19 pandemic on psychotropic prescribing: a systematic review by Nikolaos Mastellos, Marie line El Asmar, Kanika I Dharmayat, Antonio J Vallejo-Vaz, Ryan Irwin, Swettha Mahesarajah

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Elevated plasma trimethyllysine is associated with incident atrial fibrillation by Mads M Svenningsson, Gard FT Svingen, Per M Ueland, Gerhard Sulo, Espen Ø Bjørnestad, Eva R Pedersen, Indu Dhar, Dennis W. Nilsen, Ottar Nygård

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Translation of the UK Pediatric Influenza Vaccination Programme in Primary Schools to 13 European Countries Using a Dynamic Transmission Model by Laetitia Gerlier, Judith Hackett, Richard Lawson, Sofia Dos Santos Mendes, Martin Eichner

“…Symptomatic influenza cases and associated medical resources (primary care consultations [PCC], hospitalization, intensive care unit [ICU] admissions) were calculated. …”
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Regional differences in triage decisions affect hospital mortality among frail COVID-19 patients in the COvid MEdicaTion study by Julia Minnema, Roos Sablerolles, Janneke van Kempen, Hugo van der Kuy, Harmke Polinder-Bos, Bob van de Loo, Jorie Versmissen, Miriam L. Haaksma, Melvin Lafeber, Miriam C. Faes, on behalf of the COMET research team^

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Quality of life in people with syndromic heritable thoracic aortic disease and their relatives: a qualitative interview based study by Gry Velvin, Heidi Johansen, Gunnbjørg Aune, Kerstin Fugl-Meyer, Amy Østertun Geirdal

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Evaluating a multicomponent intervention for managing kidney outcomes among patients with moderate or advanced chronic kidney disease (CKD): protocol for the Strategies for Kidney... by Tazeen Hasan Jafar, Ngiap Chuan Tan, Mihir Gandhi, Sungwon Yoon, Eric Finkelstein, Peter Moey Kirm Seng, Ruiheng Ong, Anandan Gerard Thiagarajah, Bing Long Lee, Ka Chi To, Aminath Shiwaza Moosa

“…The goal of the Strategies for Kidney Outcomes Prevention and Evaluation (SKOPE) study is to establish effective multicomponent intervention (MCI) strategies for evaluating and preventing kidney outcomes in patients with moderate to advanced CKD within primary care settings in Singapore. Methods This study is a 3-year randomized controlled trial among 896 participants aged between 40 and 80 years with moderate or advanced CKD in five government-subsidized polyclinics in Singapore. …”
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Exploring the gender difference in type 2 diabetes incidence in a Swiss cohort using latent class analysis: an intersectional approach by Julien Vaucher, Michael Amiguet, Carole Clair, Joelle Schwarz, Jeanne Marie Barbier, Aurélie M Lasserre

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Prevalence of Anti-JC Virus (JCV) Antibodies in the Multiple Sclerosis (MS) Population in Cyprus: A Retrospective Study by Sakis Lambrianides, Christiana A. Demetriou, Andis Tillyris, Elena Kkolou, Eftychia Gaglia, Eleni Agkastinioti, Eleni Leonidou, Yiolanda-Panayiota Christou, Savvas S. Papacostas, Kleopas A. Kleopa, Theodoros Kyriakides, Marios Pantzaris

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Impact of the abolition of copayments on the GP-centred coordination of care in Bavaria, Germany: analysis of routinely collected claims data by Werner Maier, Antonius Schneider, Lars Schwettmann, Ewan Donnachie, Martin Tauscher, Roman Gerlach, Klaus Linde, Michaela Olm

“…Therefore, time series analyses covering 24 quarters were performed.Setting Primary care in Bavaria, Germany.Participants All statutorily insured patients in Bavaria, aged ≥18 years, with at least one ambulatory specialist contact between 2011 and 2016.Primary and secondary outcome measures Primary outcome was the percentage of patients with GP-coordinated care (every regular specialist consultation within a quarter was preceded by a GP referral). …”
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Virtual online consultations: advantages and limitations (VOCAL) study by Trisha Greenhalgh, Joe Wherton, Sara Shaw, Charles Gutteridge, Emma Byrne, Isabel Hodkinson, Shanti Vijayaraghavan, Desirée Campbell-Richards, Satya Bhattacharya, Philippa Hanson, Seendy Ramoutar, Anna Collard, Joanne Morris

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Resisting epistemic violence in global mental health: Listening to local understandings of mental health and emotional distress among victims and ex-guerrilla members in Southern C... by María Cecilia Dedios Sanguineti, Laura Fonseca, Rochelle A. Burgess, Natalia Concha, Mónica González, Norha Vera San Juan, Mónica Carreño, Kely Johana Palacio, María Fernanda Sotto, Sandra Jovchelovitch

“…Our study provides actionable insights relevant for community-based mental health and primary care services, as well as those services across sectors that can contribute to the mental health of this population.…”
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SPAGRM: effectively controlling for sample relatedness in large-scale genome-wide association studies of longitudinal traits by He Xu, Yuzhuo Ma, Lin-lin Xu, Yin Li, Yufei Liu, Ying Li, Xu-jie Zhou, Wei Zhou, Seunggeun Lee, Peipei Zhang, Weihua Yue, Wenjian Bi

“…Applying SPAGRM to 79 longitudinal traits extracted from UK Biobank primary care data, we identified 7,463 genetic loci, making a pioneering attempt to conduct GWAS for these traits as longitudinal traits.…”
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General practitioner use of D-dimer in suspected venous thromboembolism: historical cohort study in one geographical region in the Netherlands by Angel M R Schols, Eline Meijs, Geert-Jan Dinant, Henri E J H Stoffers, Mariëlle M E Krekels, Jochen W L Cals

“…Objectives To investigate how many general practitioner (GP)-referred venous thromboembolic events (VTEs) are diagnosed during 1 year in one geographical region and to investigate the (urgent) referral pathway of VTE diagnoses, including the role of laboratory D-dimer testing.Design Historical cohort study.Setting GP patients of 47 general practices in a demarcated geographical region of 161 503 inhabitants in the Netherlands.Participants We analysed all 895 primary care patients in whom either the GP determined a D-dimer value or who had a diagnostic work-up for suspected VTE in a non-academic hospital during 2015.Primary and secondary outcome measures The primary outcomes of this study were the total number of VTEs per year and the diagnostic pathways—including the role of GP determined D-dimer testing—of patients urgently referred to secondary care for suspected VTE. …”
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Attitudes and knowledge for CBT-based psychotherapy among medical students and residents in China: a survey study by Yinan Ding, Tao Pei, Pu Peng, Jiashu Yao, Jinsong Tang, Yanhui Liao

“…Methods One hundred and forty-nine participants, including medical students, residents, and other health providers (HCPs), self-reported their understanding of 18 types of psychotherapy, negative attitude towards cognitive behavioral therapy (CBT), and their attitude towards psychological interventions and counseling in primary care (APIC-PC) through an online survey. Results Participants’ understanding of psychotherapy was generally low (M = 26.25, SD = 22.99). …”
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Characterizing Telehealth Barriers and Preferences to Promote Acceptable Implementation Strategies in Central Uganda: Multilevel Formative Evaluation by Michael Kizito, Erina Nabunjo Mugabi, Sabrina Ford, Bree Holtz, Kelly Hirko

“…MethodsWe collected surveys characterizing telehealth perceptions, barriers, and preferences from health care providers and patients seeking primary care in the Central Region of Uganda from January 2022 to July 2022. …”
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Oral glucose tolerance testing as a complement to fasting plasma glucose in screening for type 2 diabetes: population-based cross-sectional analyses of 146 000 health examinations... by Patrik Wennberg, Mattias Brunström, Anna Rosén, Julia Otten, Andreas Stomby, Simon Vallin

“…Objective To assess the effect of adding an oral glucose tolerance test (OGTT) to fasting plasma glucose (FPG) in terms of detection of type 2 diabetes (T2D) and impaired glucose tolerance (IGT).Design Retrospective analysis of serial cross-sectional screening study.Setting Population-based health examinations within primary care in Västerbotten County, Sweden.Participants Individuals aged 40- 50 and 60 years with participation from 1985 to 2017. …”
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Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models by Kathleen Bennett, Frank Moriarty, Tom Fahey, Caitriona Cahir

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Medical complexity in emergency and urgent care settings: a scoping review protocol by Diane Lorenzetti, Tanvir C Turin, Sumedh Bele, Eddy Lang, Doreen Rabi, Naomi Popeski, Marie-Claire Uwamahoro, Conne Lategan, Kate Yakubets, Cassandra Chisholm

“…Introduction Considering the impact of non-medical factors (personal and social) on patients with multiple chronic conditions, the term ‘medical complexity’ is gaining traction as it encompasses both medical and non-medical aspects of patients’ medical needs. When primary care is not able to provide timely care for chronic challenges or acute concerns, complex patients require care in emergency or urgent care settings. …”
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Temporal Trends in the Utilization and Survival Outcomes of Lobar, Segmental, and Wedge Resection for Early-Stage NSCLC, 2004 to 2020 by Eden Z. Deng, BS, Xiaofei Wang, PhD, Jianrong Zhang, MD, MPH, Thomas E. Stinchcombe, MD, Chi-Fu (Jeffrey) Yang, MD, Nasser Altorki, MD

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Understanding the use of the National Early Warning Score 2 in acute care settings: a realist review protocol by Nia Roberts, Geoff Wong, Michelle Treacy, Mandy Odell

“…Documents set in the paediatric, maternity and primary care settings will be excluded. (3) Selecting documents and quality appraisal. (4) Extracting and organising the data. (5) Synthesising the data. (6) Disseminating the findings. …”
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