Severe Neurotoxicity due to Atropa belladonna Poisoning: A Case Report and Literature Review by Seyed Javad Boskabadi, Sima Ramezaninejad, Zakaria Zakariaei

“…The toxic effects of A. belladonna are attributable to its alkaloid content, which possesses potent anticholinergic properties. These alkaloids are responsible for the plant’s toxicity and can cause a range of adverse effects in humans and animals upon ingestion or contact. …”
Get full text

Endophytic Bacillus bacteria with RNase activity in the resistance of potato plants to viruses by G. F. Burkhanova, A. V. Sorokan, E. A. Cherepanova, E. R. Sarvarova, R. M. Khairullin, I. V. Maksimov

“…Many strains of Bacillus produce ribonucleases (RNases). Our laboratory possesses a collection of bacteria that produce various metabolites and have RNase activity. …”
Get full text

Functional and genomic analyses of plant growth promoting traits in Priestia aryabhattai and Paenibacillus sp. isolates from tomato rhizosphere by Carolina Almirón, Tomás Denis Petitti, María Agustina Ponso, Ana María Romero, Vanessa Andrea Areco, María Isabel Bianco, Martín Espariz, Pablo Marcelo Yaryura

“…Their genomes were initially assessed in silico through various approaches, and these observations were then compared with results obtained in vitro and in vivo. Both possess genes associated with the production of siderophores, indole acetic acid (IAA) and cytokinins (CKs), all of which have been shown to promote plant growth. …”
Get full text

Synthesis and crystal structure of anti-10-(4-cyanophenyl)-10,11,22,23-tetrahydro-9H,21H-5,8:15,12-bis(metheno)[1,5,11]triazacyclohexadecino[1,16-a:5,6-a′]diindole dichloromethane... by Koji Kubono, Keita Tani, Yukiyasu Kashiwagi

“…The asymmetric unit of the title compound is composed of one host molecule, anti-4-(19H,59H-3-aza-1,5(3,9)-dicarbazolacyclooctaphane-3-yl)benzonitrile and one dichloromethane solvate molecule, C36H28N4·CH2Cl2. The host molecule possesses a planar chirality but crystallizes as a racemate in the space group P21/c. …”
Get full text

Quasi-vertically asymmetric channels of graphene oxide membrane for ultrafast ion sieving by Changdao Han, Jie Jiang, Liuhua Mu, Wenhui Zhao, Junfan Liu, Jian Lan, Shouyuan Hu, Huan Yang, Shan Gao, Feng Zhou, Junlang Chen, Yan Fan, Xiangmei Duan, Pei Li, Liang Chen

“…The vertical channels possess very short pathway for almost direct water transport and a highly effective channel area, meanwhile the asymmetric porous template enhances the packing of the inserted GO nanosheets to avoid the swelling effect of membrane. …”
Get full text

Exploring the prognosis of calponin h1 in carcinogenesis: A novel target in biomedical research by Roshna Sankar, Sharon John, Priya Devi, Sameer Gupta, Shalini Gupta

“…One of its functions is akin to a striated muscle troponin T-like protein. Vertebrate species possess three distinct isoforms of calponin, encoded by the homologous genes CNN1, CNN2, and CNN3, whose structures and genes are elucidated in the subsequent review. …”
Get full text

Mesenchymal Stem Cells for Cartilage Regeneration of TMJ Osteoarthritis by Dixin Cui, Hongyu Li, Xin Xu, Ling Ye, Xuedong Zhou, Liwei Zheng, Yachuan Zhou

“…Mesenchymal stem cells (MSCs), derived from the bone marrow, synovium, and even umbilical cord, play a role as seed cells for the cartilage regeneration of TMJ OA. MSCs possess multilineage differentiation potential, including chondrogenic differentiation as well as osteogenic differentiation. …”
Get full text

Busting the Breast Cancer with AstraZeneca’s Gefitinib by S. Chemmalar, A. R. Intan Shameha, Che Azurahanim Che Abdullah, Nor Asma Ab Razak, Loqman Mohamad Yusof, Mokrish Ajat, Kim Wei Chan, Md Zuki Abu Bakar Zakaria

“…Gefitinib (GEF), a tyrosine kinase inhibitor of EGFR1, possesses a vast potential for treatment against breast cancer and is supported by a multiplicity of experiments. …”
Get full text

Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology by Wei Cai, Kailin Li, Shihan Qin, Pei Xiong, Jie Peng, Silin Shi, Zaiqi Zhang

“…This finding revealed that P. freyniana possessed 43 flavonoids (40 of them were first reported) with 23 core target genes, which are associated with PI3K-Akt, MAPK, TNF signaling pathway, and pathway in cancer. …”
Get full text

Salvage of Failed Local and Regional Flaps with Porcine Urinary Bladder Extracellular Matrix Aided Tissue Regeneration by Gregory J. Kruper, Zachary P. VandeGriend, Ho-Sheng Lin, Giancarlo F. Zuliani

“…Because the face and neck possess a complex three-dimensional topography, wound dressings are inherently complex to design and change. …”
Get full text

Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases by Juan Shi, Shuhong Chi, Jing Xue, Jiali Yang, Feng Li, Xiaoming Liu

“…Increasing lines of evidence have suggested a crucial role of Wnt signaling during the pathogenesis of many autoimmune diseases; in addition, some of microRNAs (miRNAs), a class of small, noncoding RNA molecules capable of transcriptionally regulating gene expression, have also recently been demonstrated to possess both physiological and pathological roles in autoimmune diseases by regulating the Wnt signaling pathway. …”
Get full text

On geometry of fixed figures via φ−interpolative contractions and application of activation functions in neural networks and machine learning models by Khairul Habib Alam, Yumnam Rohen, Anita Tomar, Mohammad Sajid

“…We also partially address an open problem demonstrating that a JS−contraction possesses a fixed elliptic disc. This property extends to smaller discs and ellipses within a complete mvb−metric space. …”
Get full text

Occupational Hazards Knowledge among a Sample of Medical and Paramedical Staff in Baghdad City by Sajjad M. hasan, Suhair M. Hassoun, Luma H. Ali

“… Occupational hazards include any behaviors which possess the potential to cause or raise risks at the workplace, as well as the compounding effects of accidents and occupational diseases within workers in the health and medical field. …”
Get full text

Analgesic effect of ethylacetate fraction of the methanol leaves extract of Hannoa klaineana in rats by Ibrahim Abubakar, Mu'azu Abubakar Gusau, Jabir Aliyu Danyaya, Shehu Ibrahim, Zayyanu Abdullahi, Abdulhakim Zubairu, Abdulsalam Umar Sahabi

“…Findings from this study show that ethylacetate fraction of the methanol leaves extract of Hannoa klaineana possessed analgesic activity which provided justification for the local use of the plant in the treatment of pain.…”
Get full text

Competencies required for the performance of primary health care managers: a systematic review by Katherine Soto-Schulz, Raúl Herrera-Echenique, Rodrigo Brito-Díaz, Nuria Pérez-Romero

“…Primary health care managers must possess specific competencies to effectively perform their roles, given the relevance of primary care in each country’s health system. …”
Get full text

Predicting Flash Point of Organosilicon Compounds Using Quantitative Structure Activity Relationship Approach by Chen-Peng Chen, Chan-Cheng Chen, Hsu-Fang Chen

“…The flash point (FP) of a compound is the primary property used in the assessment of fire hazards for flammable liquids and is amongst the crucial information that people handling flammable liquids must possess as far as industrial safety is concerned. …”
Get full text

Mitochondrial diseases: from molecular mechanisms to therapeutic advances by Haipeng Wen, Hui Deng, Bingyan Li, Junyu Chen, Junye Zhu, Xian Zhang, Shigeo Yoshida, Yedi Zhou

“…Abstract Mitochondria are essential for cellular function and viability, serving as central hubs of metabolism and signaling. They possess various metabolic and quality control mechanisms crucial for maintaining normal cellular activities. …”
Get full text

Hydrogen-Rich Saline Inhibits NLRP3 Inflammasome Activation and Attenuates Experimental Acute Pancreatitis in Mice by Jian-Dong Ren, Jie Ma, Jun Hou, Wen-Jin Xiao, Wei-Hua Jin, Juan Wu, Kai-Hua Fan

“…Hydrogen-rich saline (HRS), a well-known ROS scavenger, has been shown to possess therapeutic benefit on AP in many animal experiments. …”
Get full text

The Effectiveness of Emotion-oriented Therapy on Oppositional Defiant Disorder Symptoms and Anxiety in ODD Children by Zahra Nasiri Nasab, Tayebeh Jamali, Sepideh Hassanzadeh Hajiabadi, Seyedamirhossein Hojabri, Marzieh Shahabinejad, Seddigheh Iranmanesh

“…The findings indicated that emotion-oriented therapy possesses the ability to influence both the symptoms of defiant disorder and anxiety symptoms in children suffering from oppositional defiant disorder. …”
Get full text

Leptospira and Inflammation by C. F. Gonçalves-de-Albuquerque, P. Burth, A. R. Silva, M. Younes-Ibrahim, H. C. Castro-Faria-Neto, M. V. Castro-Faria

“…This paper will discuss both the role of immunogenic and pathogenic molecules during leptospirosis infection and possible new targets for immunotherapy against leptospira components. Leptospira, possess a wide variety of mechanisms that allow them to evade the host immune system and cause infection. …”
Get full text