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521
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability
Published 2024-12-01“…Side-by-side developability assessment of both h1340.CC and h1340.SA.LV indicate that they possess similar, favorable properties. Next, and prompted by recent developments in machine learning (ML)-guided protein engineering, we used an unbiased ML- and structure-guided approach to rapidly and efficiently generate a different variant with recovered affinity. …”
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522
Phylogenetic analysis, metabolic profiling, and environmental adaptation of strain LCG007: a novel Rhodobacteraceae isolated from the East China Sea intertidal zone
Published 2025-01-01“…Strain LCG007, isolated from Lu Chao Harbor's intertidal water, phylogenetically represents a novel genus within the family Rhodobacteraceae. Metabolically, it possesses a wide array of amino acid metabolic genes that enable it to thrive on both amino acids or peptides. …”
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523
L’enseignant dans la pensée de Castoriadis : évaluation et clôture symbolique dans l’éducation
Published 2014-09-01“…It is necessary to examine this paradox between the situation of the teacher in Castoriadis must remove the student from the possession of knowledge and evaluative practice in examination classes. …”
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524
Projectile Balloting Attributable to Gun Tube Curvature
Published 2010-01-01“…This paper starts with the presentation of a deterministic barrel model that possesses both vertical and lateral deviations from centerline in accordance with measurement data, followed by a novel approach to simulating comprehensive barrel centerline variations for the investigation of projectile balloting^1 motions. …”
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525
Black humour processing in the light of the conceptual integration theory and the benign violation theory
Published 2019-10-01“…The paper shows that theories, though different, possess certain common elements and represent useful tools in humour processing. …”
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526
The Bacterial Microflora of Fish, Revised
Published 2006-01-01“…The results of numerous studies indicate that fish possess bacterial populations on or in their skin, gills, digestive tract, and light-emitting organs. …”
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527
McEliece public key cryptosystem attack algorithm based on enumeration error vector
Published 2014-05-01“…The Hamming weight of error vector is less than the code length, and M public key cryptosystem based on Goppa code possesses low weight public code words. Considering the above analysis, an attack algorithm based on enumeration error vector was proposed. …”
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528
Heterogeneous redundancies scheduling algorithm for mimic security defense
Published 2018-07-01“…The scheduling of heterogeneous redundancies is one of the key lines of mimic security defense,but the existing scheduling strategies are lack of consideration about the similarity among redundancies and the scheduling algorithms are incomprehensive.A new scheduling algorithm called random seed & minimum similarity (RSMS) algorithm was proposed,which combined dynamics and reliability by determining a scheduling scheme with minimum global-similarity after choosing a seed-redundancy randomly.Theoretical analysis and simulation results show that RSMS algorithm possessed a far longer scheduling cycle than maximum dissimilarity algorithm,as well as a far lower failure rate than random scheduling algorithm,which represents an effective balance between dynamics and reliability.…”
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529
New Results on Stability of Delayed Cohen–Grossberg Neural Networks of Neutral Type
Published 2020-01-01“…This research work conducts an investigation of the stability issues of neutral-type Cohen–Grossberg neural network models possessing discrete time delays in states and discrete neutral delays in time derivatives of neuron states. …”
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530
Thermal Spin Transport Properties in Diarylethene-Based Molecule Devices
Published 2022-01-01“…Moreover, the mentioned currents possess approximately the same magnitudes, indicating a nearly nondissipative spin Seebeck effect. …”
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531
PROFESSOR WORK AT UNIVERSITY: DAILY PROBLEMS AND SOLUTIONS
Published 2016-12-01“…Distance courses have additional options for teaching students, and possess a shared location for all necessary learning materials in every discipline. …”
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532
Fronteiras terrestres da Espanha: os enclaves e as disputas geopolíticas
Published 2020-09-01“…It is a set of enclaves, the possession of which, in some cases, is claimed simultaneously by Madrid and neighboring countries. …”
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533
Duality by reproducing kernels
Published 2003-01-01“…The duality itself takes place only for those domains 𝒟 which possess certain convexity properties with respect to A.…”
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534
On the Minimum General Sum-Connectivity of Trees of Fixed Order and Pendent Vertices
Published 2022-01-01“…This paper addresses the problem of finding graphs possessing the minimum χα value over the class of all trees with a fixed order n and fixed number of pendent vertices n1 for α>1. …”
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535
Entre passé et présent, entre migration et exil : les Espagnols et leurs descendants au Venezuela
Published 2017-04-01“…Therefore, the aim of this article is to study the Spanish and their descendants as a whole, which may possess its own internal logic - despite its heterogeneity. …”
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536
Some Real-Life Applications of a Newly Designed Algorithm for Nonlinear Equations and Its Dynamics via Computer Tools
Published 2021-01-01“…The convergence analysis shows that the newly designed algorithm possesses fourth-order convergence. To demonstrate the applicability of the designed algorithm, we consider five real-life engineering problems in the form of nonlinear scalar functions and then solve them via computer tools. …”
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537
Tropical Spiderwort (Commelina benghalensis L.), Identification and Control
Published 2004-07-01“…Tropical spiderwort also possesses the ability to root at the nodes and can be propagated from cut stems. …”
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538
Casuarina equisetifolia, Australian Pine
Published 2012-10-01“…Today it is considered a category I invasive species in Florida, and the Division of Plant Industry strictly prohibits possessing, transporting, and cultivating this species. …”
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539
Some critical issues of content sharing network
Published 2016-10-01“…As a sharing platform for files,information and resources,CSN (content sharing network) possessed a very wide distribution in Internet.It did provide a great convenience for people to share various contents through Internet with the rapid development and wide application of network techniques,especially the emergence and prevalence of P2P (peer-to-peer).However,numerous malicious files,cheating information and spywares swarmed into Internet,which pose a serious threat to the security of CSN.A survey was made of some critical issues of CSN combining with the current development and research status from the perspective of network security.The critical issues include the definition and important properties,different taxonomies of types,key techniques,developing and researching trends of CSN.…”
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540
O ensino de Ciências Sociais na Faculdade Catarinense de Filosofia
Published 2018-01-01“…It is important to note the character of the formation of a cultural elite that the institution possessed, and the affinity of the discussions developed in this space with the intellectual debate of that time.…”
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