Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] by Fewzia Shikur Mohammed, Amel Beshir Mohammed, Shimelis Doni Nigusse, Feleke Tilahun Zewdu, Abebaw Yeshambel Alemu, Teklu Cherkose, Kidist Bobosha, Eshetu Molla, Iris Mosweu, Vanessa Yardley, Saba Maria Lambert, Mirgissa Kaba, Endalamaw Gadisa, Yohannes Hailemichael, Catherine Pitt, Elizabeth Allen, Stephen L. Walker, Michael Marks

Get full text

Delineation of the Genetic Architecture and Clinical Polymorphism of 3q29 Duplication Syndrome: A Review of the Literature and a Report of Two Novel Patients With Single‐Gene BDH1... by A. A. Kashevarova, M. E. Lopatkina, O. Yu. Vasilyeva, D. A. Fedotov, A. D. Lobanov, E. A. Fonova, I. Z. Zhalsanova, A. A. Zarubin, O. A. Salyukova, E. O. Belyaeva, V. V. Petrova, E. G. Ravzhaeva, A. A. Agafonova, A. D. Cheremnykh, N. B. Torkhova, S. L. Vovk, I. N. Lebedev

Get full text

Short-Interval Self-Learning to Improve Retention of Resuscitation Skills: A Randomized Controlled Trial

“…Méthodologie: cette étude qui se fera sous forme d’essai comparatif à répartition aléatoire par grappe aura lieu de septembre 2018 à septembre 2020. La population cible sera constituée d’employés de plusieurs organisation suivant une formation diplômante aux premiers secours de trois jours à la Croix Rouge belge. …”
Get full text

School-based mindfulness training in early adolescence: what works, for whom and how in the MYRIAD trial? by Susan Ball, Obioha C Ukoumunne, Tamsin Ford, Sarah Byford, Tim Dalgleish, Willem Kuyken, Jesus Montero-Marin, Kate Tudor, Alice Tickell, Catherine Crane, Ariane Petit, Elise Sellars, Laura Taylor, Maris Vainre, Benjamin Jones, Kirsty Griffiths, Elizabeth Nuthall, J Mark G Williams, Sarah-Jayne Blakemore, Katie Fletcher, Emma Medlicott, Anam Raja, Matthew Allwood, Louise Aukland, Tríona Casey, Nicola Dalrymple, Katherine De Wilde, Eleanor-Rose Farley, Jennifer Harper, Nils Kappelmann, Maria Kempnich, Liz Lord, Lucy Palmer, Alice Philips, Isobel Pryor-Nitsch, Lucy Radley, Anna Sonley, Jem Shackleford, Mark T Greenberg, Verena Hinze, Saz Ahmed, Marc Bennett, Lucy Foulkes, Cait Griffin, Konstantina Komninidou, Rachel Knight, Suzannah Laws, Jovita Leung, Jenna Parker, Blanca Piera Pi-Sunyer, Ashok Sakhardande, Lucy Warriner, Brian Wainman

Get full text

Real-World Evidence of Clinical Outcomes of the Use of the Adalimumab Biosimilar SB5 in Rheumatic and Gastrointestinal Immune-Mediated Inflammatory Diseases: 12-Month Data from the... by Bruno Fautrel, Yoram Bouhnik, Carine Salliot, Franck Carbonnel, Mathurin Fumery, Christophe Bernardeau, Yves Maugars, Mathurin Flamant, Fabienne Coury, Ben Braithwaite, Salima Hateb, Janet Addison, the PERFUSE investigators

“…Persistence was comparable between naïve and switched populations, though the reasons for non-persistence differed. …”
Get full text

Association of depression in multiple sclerosis with fatigue, sleep disturbances, disability, and health-related quality of life: Outcomes of a cross-sectional study by E. Aparicio-Castro, A. Candeliere-Merlicco, C.M. Santa, R. Villaverde-González

“…Introduction: Depression affect individuals with multiple sclerosis (MS) more frequently compared with the general population. It can worsen the symptoms of MS, influence disability progression, and significantly reduce the quality of life (QoL). …”
Get full text

Medical Jousting: Going for the kill! by Dr.Fuad Ahmed Khan Niazi

“…This may potentiate a surge in an already alarming tendency of violence, among a certain segment of our population, against hospitals and healthcare workers. …”
Get full text

Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

“…The reliability of the difference between the two averages was determined by the student's t‑test for unrelated populations.Results. In clear cell kidney cancer, a low level of proliferative activity was observed in General, but in generalized, compared with local, it was significantly higher (P<0.05) (8±0.5% and 5±0.6%, respectively), and in generalized cancer, there was an overexpression of Cyclin D1–70±3.9%, compared to 14.4±2.3% in local stages, P<0.05. …”
Get full text

Comparison of cardiovascular risk prediction models developed using machine learning based on data from a Sri Lankan cohort with World Health Organization risk charts for predictin... by Anuradhani Kasturiratne, Hithanadura Janaka de Silva, Chamila Mettananda, Anuradha Supun Dassanayake, Norihiro Kato, Rajitha Wickremasinghe, Maheeka Solangaarachchige, Prasanna Haddela

“…Introduction Models derived from non-Sri Lankan cohorts are used for cardiovascular (CV) risk stratification of Sri Lankans.Objective To develop a CV risk prediction model using machine learning (ML) based on data from a Sri Lankan cohort followed up for 10 years, and to compare the predictions with WHO risk charts.Design Cohort study.Setting The Ragama Health Study (RHS), an ongoing, prospective, population-based cohort study of patients randomly selected from the Ragama Medical Office of Heath area, Sri Lanka, focusing on the epidemiology of non-communicable diseases, was used to develop the model. …”
Get full text

Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a... by Chris Metcalfe, Jenny Donovan, Julia Wade, Vincent J Gnanapragasam, Michael Davis, David Neal, Richard Martin, Athene Lane, Edward Rowe, Freddie Hamdy, James Catto, Emma Turner, David Gillatt, Eleanor Walsh, Derek Rosario, Tim Peters, Roger Kockelbergh, Alan Paul, Peter Holding, Howard Kynaston, Owen Hughes, Prasad Bollina, Alan Doherty, Edgar Paez

Get full text

Presenting a Framework of Effective Factors on the Implementation of Policies in the Field of Protection and Exploitation of Forests in the North of the Country by Davoud Hosseinpoor, Seyed Mahdi Alvani, Hossein Aslipour, Aghil Ghorbani Paji

“…The research adopted a sequential or successive method for targeted sampling, ensuring that the sample accurately reflected the population of interest. In the qualitative section, the study engaged 14 experts with substantial experience in the field, achieving theoretical saturation after conducting in-depth interviews with 12 of these participants. …”
Get full text

Résultats préliminaires de l’utilisation de la malle pédagogique sur les Grands Singes et leur habitat à Kinshasa by Pierrot Mbonzo, Blaise Mbuaki, Claudine André

“…Avec l’utilisation à Kinshasa de la malle pédagogique « les Grands singes et leur habitat » créée par l’Association Projet pour la Conservation des Grands Singes et mise à disposition par le RAPAC (Réseau des Aires Protégées d’Afrique Centrale), le programme d’Education au sanctuaire « Lola ya bonobo » s’est fixé les quatre objectifs suivants : (1) Relever les similarités des Grands singes entre eux et avec l’homme, (2) Ressortir l’importance de la forêt pour les Grands singes et la nécessité à la conserver, (3) Susciter l’intérêt des participants à protéger les Grands singes, (4) Contribuer au changement de comportement des populations pour la protection des Grands singes. Ce présent rapport présente les résultats de la sensibilisation des enfants d’environ 11 à 12 ans avec le module « Forêt, habitat des Grands singes ». …”
Get full text

Most prevalent jobs of young master’s degree graduates by detailed field of study by Marc Frenette, Tomasz Handler

“…The purpose of this short article is to present results for master’s degree graduates aged 25 to 34 collected on the 2021 Census of Population. Only individuals who worked during the census reference week (May 2 to 8, 2021) and who completed a Canadian master’s degree program are included. …”
Get full text

Le Proyecto Mono Tocon : recherche, éducation et conservation, au Pérou by Audrey Gaultier, Rosario Huashuayo‑Llamocca, Antonio Boveda‑Penalba, Jan Vermeer

“…L’accent est alors mis sur la gestion durable des ressources naturelles, le renforcement des capacités et la sensibilisation des populations locales. Dans le but de sauvegarder Callicebus oenanthe, l’une des stratégies du PMT est la création de corridors écologiques dans toute la région de San Martin. …”
Get full text

Definition of sinonasal and otological exacerbation in patients with primary ciliary dyskinesia: an expert consensus by Myrofora Goutaki, Yin Ting Lam, Andreas Anagiotos, Miguel Armengot, Andrea Burgess, Raewyn Campbell, Mathilde Carlier, Nathalie Caversaccio, Neil K. Chadha, Berat Demir, Sinan Ahmed D. Dheyauldeen, Onder Gunaydin, Amanda Harris, Isolde Hayn, Deniz Inal-Ince, Eric Levi, Trini Lopez Fernandez, Jane S. Lucas, Bernard Maitre, Anne-Lise M.L. Poirrier, Lynne Schofield, Kazuhiko Takeuchi, Christine van Gogh, Nikolaus E. Wolter, Jean-François Papon

Get full text

A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province by Jie ZHOU, Ling LI, Ji ZHANG, Lisha YU, Yujin REN, Wei JI, Yingjiao MU, Tao LIU

“…ObjectiveTo investigate the impact of healthy lifestyles on all-cause and cardiovascular disease (CVD) mortality among adult residents in Guizhou province, and to provide a reference for reducing mortality risk in the local population. MethodsA prospective cohort study was conducted using a multi-stage cluster random sampling method to recruit 9 280 permanent residents aged ≥ 18 years in Guizhou province from November 2010 to December 2012 for a baseline survey. …”
Get full text

Number of children and dementia risk: a causal mediation analysis using data from the HUNT study linked with national registries in Norway by Teferi Mekonnen, Vegard Skirbekk, Ekaterina Zotcheva, Bo Engdahl, Bernt Bratsberg, Astanand Jugessur, Catherine Bowen, Geir Selbæk, Hans-Peter Kohler, Jennifer R. Harris, Sarah E. Tom, Steinar Krokstad, Trine Holt Edwin, Yehani Wedatilake, Katrin Wolfova, Dana Kristjansson, Yaakov Stern, Asta Kristine Håberg, Bjørn Heine Strand

Get full text

Identifying joint association between body fat distribution with high blood pressure among 7 ∼ 17 years using the BKMR model: findings from a cross-sectional study in China by Manman Chen, Xijie Wang, Yanhui Li, Di Gao, Ying Ma, Tao Ma, Yi Zhang, Li Chen, Jieyu Liu, Qi Ma, Mengjie Cui, Xinxin Wang, Tongjun Guo, Wen Yuan, Yanhui Dong, Jun Ma

Get full text

Descriptions anatomiques et hypothèses étiologiques des déformations des mains et des pieds observées chez les chimpanzés de Sebitoli (Parc national de Kibale, Ouganda) by Pauline Couchoud, Marie Cibot, Emmanuelle Pouydebat, Sabrina Krief

“…En effet, bien que l’accès au parc soit interdit à la population locale, des cultures vivrières, des plantations d’eucalyptus et de thé, ainsi que de nombreux villages (262-335 habitants/km2) circonscrivent la forêt. …”
Get full text

Providing digital human resource management model by Seyed Reza Akramian, amin nikpour, Hamid Reza Mollaei, Mohammad Jalal Kamali, Hojjat Talebi

“…The current research is applicable-developmental in terms of purpose, descriptive in terms of information gathering, and qualitative in terms of the nature of the data. The statistical population of the research includes specialists and experts familiar with digital human resource management topics. …”
Get full text