Improving the diagnostic accuracy of referrals for papilloedema (DIPP) study: protocol for a mixed-methods study by Luke Bennetto, Beth Stuart, Jonathan Benger, Matthew J Ridd, Helen Bolton, William Hollingworth, Michael Bowen, Amar Shah, Samuel William David Merriel, Alyson Huntley, Victoria Wilson, Maria Theresa Redaniel, Paul Roy, Denize Atan, Frank Moore, Olivia Skrobot, Mary-Ann Sherratt, Marcia Lucraft, Christina Stokes

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Remote Lifestyle Intervention to Reduce Postpartum Weight Retention: Protocol for a Community-Engaged Hybrid Type I Effectiveness-Implementation Randomized Controlled Trial by Lindsay M Martin, Christine D McKinney, Lia Escobar Acosta, Janelle W Coughlin, Noelene K Jeffers, Alexandra Solano-Umaña, Kathryn A Carson, Nae-Yuh Wang, Wendy L Bennett, Kelly M Bower

“…In this paper, we highlight the community-engaged approach and trial design features that enable the implementation of the intervention within home visiting and demonstrate its applicability to the target population. Participants will be 360 pregnant individuals with overweight or obesity enrolled between 20 and 33 weeks of gestation and randomized 1:1 to Healthy for Two–Home Visiting or usual home visiting services. …”
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High tumor mutational burden predicts favorable response to anti-PD-(L)1 therapy in patients with solid tumor: a real-world pan-tumor analysis by Sehhoon Park, Jaeyun Jung, You Jeong Heo

“…In contrast, exhausted T-cell and M2 macrophage counts were increased in the non-responder group.Conclusions The overall incidence of TMB status was analyzed by the TSO500 assay, and TMB-H was observed in 14.7% of the pan-cancer population. In a real-world setting, TMB-H identified by a target sequencing panel seemed to predict response to anti-PD-(L)1 therapy, especially in patients with a higher proportion of immune cells enriched in the tumor region.…”
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Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort by Kristin Ottarsdottir, Åsa Tivesten, Claes Ohlsson, Ying Li, Margareta Hellgren, Ulf Lindblad, Bledar Daka

“…Methods This is an observational cross-sectional study on the Vara-Skövde cohort, a Swedish population-based study for longitudinal surveillance of the development and progress of type 2 diabetes and hypertension. …”
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Conditional cash transfer program and child mortality: A cross-sectional analysis nested within the 100 Million Brazilian Cohort. by Dandara Ramos, Nívea B da Silva, Maria Yury Ichihara, Rosemeire L Fiaccone, Daniela Almeida, Samila Sena, Poliana Rebouças, Elzo Pereira Pinto Júnior, Enny S Paixão, Sanni Ali, Laura C Rodrigues, Maurício L Barreto

“…<h4>Methods and findings</h4>This is a cross-sectional analysis nested within the 100 Million Brazilian Cohort, a population-based cohort primarily built from Brazil's Unified Registry for Social Programs (Cadastro Único). …”
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Provincial distribution and predictors of desire for more children among married and cohabiting women in Sierra Leone by Augustus Osborne

“…This high fertility rate impacts population growth, straining resources like healthcare and education. …”
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Active biomonitoring in streams by using multimarker approaches of mussels by T. Ukasha, N.U.H. Faisal, B.K. Adji, A.P. Nugroho

“…BACKGROUND AND OBJECTIVES: Streams that pass through densely populated areas and business and industrial centers are continuously threatened by various pollutants, including metals and microplastics, originating from dispersed sources. …”
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Plasma fibronectin is a prognostic biomarker of disability in Parkinson’s disease: a prospective, multicenter cohort study by Shuzhen Zhu, Hualin Li, Zifeng Huang, Yiheng Zeng, Jianmin Huang, Guixia Li, Shujuan Yang, Hang Zhou, Zihan Chang, Zhenchao Xie, Rongfang Que, Xiaobo Wei, Minzi Li, Yanran Liang, Wenbiao Xian, Mengyan Li, Ying Pan, Fanheng Huang, Lin Shi, Chengwu Yang, Chao Deng, Lucia Batzu, Karolina Poplawska-Domaszewicz, Shuhan Chen, Ling-Ling Chan, K Ray Chaudhuri, Eng-King Tan, Qing Wang

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Hubungan antara Indeks Massa Tubuh dengan Kadar Nitrit Oksid pada Masyarakat Etnik Minangkabau di Kota Padang by Nidia Purwadianti, Fadil Oenzil, Delmi Sulastri

“…The research design was cross sectional study, the population was Minangkabau ethnic group in the age group of 30-65 years old from 4 selected districts in Padang. …”
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Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medica... by Zakhour R, Khafaja S, Korman R, Boutros CF, El Zein Z, Chmaisse A, Haj M, Haddara A, El-Houry Z, Jbahi M, Chamseddine S, Bou Karroum S, Al Oweini D, Youssef YS, Youssef N, Nasser M, Fayad D, Abi Farraj F, El Nakib C, Isaac I, Lteif M, Araj GF, Dbaibo GS

“…This poses a significant threat to the pediatric population and underscores the importance of implementing antimicrobial stewardship programs and infection control policies, which are crucial to cope with the burden of these infections, especially in the presence of other ongoing challenges such as the current economic collapse and ongoing war leading to severe antimicrobial shortages.Keywords: adolescents, antimicrobial resistance, children, gram-negative bacteria, multidrug resistance…”
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Factors and Reasons Associated with Hesitating to Seek Care for Migraine: Results of the OVERCOME (US) Study by Robert E. Shapiro, Eva Jolanda Muenzel, Robert A. Nicholson, Anthony J. Zagar, Michael L. Reed, Dawn C. Buse, Susan Hutchinson, Sait Ashina, Eric M. Pearlman, Richard B. Lipton

“…The aim of this study, in a large adult population sample in the United States (US), was to identify factors associated with and reasons for hesitating to seek healthcare for migraine. …”
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Scoping review of costs of implementation strategies in community, public health and healthcare settings by Hongmei Wang, Jungyoon Kim, Tzeyu L Michaud, Emiliane Pereira, Gwenndolyn Porter, Caitlin Golden, Jennie Hill, Cindy Schmidt, Paul A Estabrooks

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Prevalence of Site-Specific Mycoplasma genitalium Infection and Macrolide and Fluoroquinolone-Associated Mutations in Men Who Have Sex with Men in Shenzhen, China by Leng X, Zhu R, Ao X, Zhou Y, Zhang K, Hu T, Wu J, Chen Z, Huang L, Huang N, Li X, Ahmed Alnour R, Xue Z, Zhang X, Liu H, Axirejiang T, Ke W, Zou H

“…Mutations in the parC and gyrA genes were detected in 33.3% (1/3) and 33.3% (2/6) of specimens, respectively.Conclusion: We observed a high prevalence of MG infections at different anatomic sites among the MSM population in Shenzhen, China. The high prevalence of macrolide and fluoroquinolone-resistant MG underscores the importance of implementing resistance-guided therapy, establishing surveillance networks, and exploring new antibiotics against MG.Keywords: antimicrobial resistance, Mycoplasma genitalium, MSM, macrolide, fluoroquinolone…”
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Target Groups for a Short Dexamethasone Course among Critically Ill COVID-19 Patients by Armen Oganesyan, Ruslan Menzulin, Yury Surovoy, Andrei Nikiforchin, Kirill Zykov

“…Despite emerging data, assessed populations and regimens vary, and there are patient subgroups whose response to steroids remains unclear. …”
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Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset by Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Sung Hyun Lee, Chul Park

“…SMA/BMI best reflected the loss of muscle mass in healthy populations by age, showing a more remarkable decrease in muscle mass in men than in women. …”
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Dietary intakes, food behaviours, and health indicators among Métis youth in Manitoba, Canada by Chantal Perchotte, Olena Kloss, Joyce Slater, Alan Katz, Bhanu Pilli, Aynslie Hinds, Marcelo L Urquia, Julianne Sanguins, Chris Green, Jaime Cidro, Dan Chateau, Nathan Nickel, Thomas Falkenberg

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Bifurcation analysis of multistability and hysteresis in a model of HIV infection by I. V. Mironov, M. Yu. Khristichenk, Yu. M. Nechepurenko, D. S. Grebennikov, G. A. Bocharov

“…In particular, the results of the study of the HIV-1 infection model for parameter sets corresponding to different phenotypes of disease dynamics (typical, long-term non-progressing and rapidly progressing courses) indicate that an effective functional treatment (cure) of HIV-1-infected patients requires the development of a personalized approach that takes into account both the properties of the HIV-1 quasispecies population and the patient’s immune status.…”
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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

“…This study aimed to investigate the prevalence of JCPyV and BKPyV in UTUC and their correlation with cancer progression among the southwest Taiwanese population from 2020 to 2022. Methods A total of 72 paraffin-embedded UTUC tissue samples and 41 adjacent tissue samples were collected from 72 patients. …”
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95-95-95 HIV indicators among children younger than 15 years in South Africa: results from the 2017 national HIV prevalence, incidence, behaviour, and communication survey by Rindidzani E. Magobo, Musawenkosi Mabaso, Sean Jooste, Lesiba Molopa, Inbarani Naidoo, Leickness Simbayi, Khangelani Zuma, Nompumelelo Zungu, Olive Shisana, Sizulu Moyo

“…Methods The data was collected as part of the 2017 cross-sectional, multistage cluster randomized population-based household National HIV survey. Age-appropriate structured questionnaires were utilized to gather sociodemographic data, HIV-related knowledge, risk behaviours, and health-related information. …”
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Global burden, trends, and disparities in kidney cancer attributable to smoking from 1990 to 2021 by Siyu Han, Shiyu Zhao, Ran Zhong, Peizhe Li, Yuewen Pang, Shuang He, Junyao Duan, Huijie Gong, Jing Shi, Li Liu, Yongji Yan

“…However, significant demographic and geographic disparities persist, with the disease burden remaining higher in older populations and regions with elevated SDI levels. Moreover, while the overall burden is projected to decline annually over the next 15 years, it is expected to remain significantly higher in men. …”
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