Knowledge, attitudes and behaviour towards ticks and tick-borne diseases—A survey among Lyme borreliosis cases in Bavaria in 2019 by Stefanie Böhm, Volker Fingerle, Andreas Beyerlein, Manfred Wildner, Merle M. Böhmer

“…This study aims to address knowledge, attitudes, and behaviours among LB cases, a population group at increased exposure to ticks, tick bites and repeated infections.We invited Bavarian LB cases reported between weeks 23 and 35 in 2019 to participate in a questionnaire study. …”
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Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway by Jian-Hong Lin, Pei-Ching Ting, Wen-Sen Lee, Hung-Wen Chiu, Chun-An Chien, Chin-Hung Liu, Li-Yi Sun, Kun-Ta Yang

“…Cotreatment with PAME and Na+/H+ exchanger inhibitors together further reduced the intracellular pH but did not affect the PAME-induced decreases of cell proliferation and increases of the cell population at the G2/M phase. Cotreatment with PAME and a calcium chelator together inhibited the PAME-increased intracellular Ca2+ levels but did not affect the PAME-induced cell proliferation inhibition and G2/M cell cycle arrest. …”
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Analysis of drought and extreme precipitation events in Thailand: trends, climate modeling, and implications for climate change adaptation by José Francisco de Oliveira-Júnior, David Mendes, Helder Dutra Porto, Kelvy Rosalvo Alencar Cardoso, José Augusto Ferreira Neto, Emannuel Bezerra Cavalcante da Silva, Marlúcia de Aquino Pereira, Monica Cristina Damião Mendes, Bernardo Bruno Dias Baracho, Punyawi Jamjareegulgarn

“…Projections based on climate indices indicate that Thailand needs to adopt mitigation measures across its regions to neutralize the impacts of extreme drought and rainfall events on socioeconomic sectors, particularly in tourism, industry, agricultural production, and food security for its population.…”
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Predictors of Colorectal Cancer Screening and Screening Modalities among Patients seen at Federally Qualified Health Centers Funded by the United States Health Resources and Servic... by Megan R.M. Aaronson, Nadereh Pourat, Connie Lu, Jayraan Badiee, Helen Yu-Lefler, Benjamin Picillo, Hank Hoang, Folasade P. May

“…Increasing CRC screening in low-income populations requires improving access and promoting opportunities for less invasive screening.…”
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Genotyping of potato samples from the GenAgro ICG SB RAS collection using DNA markers of genes conferring resistance to phytopathogens by I. V. Totsky, I. V. Rozanova, A. D. Safonova, A. S. Batov, Yu. A. Gureeva, E. K. Khlestkina, A. V. Kochetov

“…An important step in this process is the selection of resistant genotypes from the population and the estimation of the resistance of hybrids obtained by crosses during the breeding process. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…MWPC thresholds were proposed for all other domains and summary scores.ConclusionThe study results demonstrate that the QOL-E is generally fit for purpose to assess treatment effects in populations with LR-MDS and the proposed MWPC thresholds can be used to assess within-patient treatment effect on PROs, as assessed by the QOL-E, in future studies.…”
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A multidimensional assessment of adverse events associated with paliperidone palmitate: a real-world pharmacovigilance study using the FAERS and JADER databases by Siyu Lou, Zhiwei Cui, Yingyong Ou, Junyou Chen, Linmei Zhou, Ruizhen Zhao, Chengyu Zhu, Li Wang, Zhu Wu, Fan Zou

“…However, real-world studies assessing its safety in large populations are lacking. As such, this study aimed to comprehensively evaluate real-world adverse drug events (ADEs) linked to paliperidone palmitate by employing data mining techniques on the U.S. …”
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Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial by Jordan M. Cloyd, MD, Rakhsha Khatri, BA, Angela Sarna, BS, Lena Stevens, PhD, Victor Heh, PhD, Mary Dillhoff, MD, Alex Kim, MD, Timothy M. Pawlik, MD, PhD, MPH, Aslam Ejaz, MD, Sharla Wells-Di Gregorio, PhD, Erin Scott, MD, Sachin S. Kale, MD

“…Given the unique and complex care needs of this patient population, additional research is needed to optimize supportive care strategies.…”
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Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa by W M Simmonds, Y Awuku, C Barrett, M Brand, K Davidson, D Epstein, E Fredericks, S Gabriel, S Grobler, C Gounden, L Katsidzira, V J Louw, V Naidoo, C Noel, E Ogutu, N Ramonate, N Seabi, M Setshedi, J Van Zyl, G Watermeyer, C Kassianides

“…Over 30% of the world’s population is anaemic, with a significant proportion of these being iron deficient. …”
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Radiation to all macroscopic sites of tumor permits greater systemic antitumor response to in situ vaccination by Zachary S Morris, Paul M Sondel, Amy K Erbe, Alexander L Rakhmilevich, Amber M Bates, Peter M Carlson, Alexander A Pieper, Ravi B Patel, Jen Birstler, Joseph Grudzinski, Reinier Hernandez, Bryan P Bednarz, Jamey P Weichert, Arika S Feils, Matthew Rodriquez, Claire Sun, Ian Marsh

“…Flow cytometry was used to evaluate immune population changes in both tumors.Results Abscopal effects of local ISV were amplified by delivering as little as 2–6 Gy of EBRT to the secondary tumor. …”
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Shedding light on the existence of Furan fatty acids in latex lipids across a wide diversity of Hevea brasiliensis genotypes by Chaisiri Kitpaosong, Siriluck Liengprayoon, Erwann Durand, Tucksin Lerksamran, Aurélie Daval, Eric Gohet, Lim Khan Tiva, Phean Chetha, Kong Mengchheang, Phen Phearun, Ung Rattana, Kim Chandy, Pol Sokea, Un Kim Eng, Kittipong Rattanaporn, Bruno Barea, Laurent Vaysse

“…Based on knowledge of the parentage of the studied clones, a trait heritability study was conducted and genotype PB5/51 was identified as a very worthwhile genitor for improving furan fatty acid contents in a breeding population.…”
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Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

“…Discussion The study population of patients with ED-SCLC has a poor prognosis. …”
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Improving NGOs’ participation in implementing HIV preventive interventions: a case of adolescents with high-risk behaviors in Iran by Haniye Sadat Sajadi, Laleh Ghadirian, Azadeh Sayarifard, Fatemeh Rajabi, Maryam Nazari, Narges Rostamigooran, Nina Loori, Haniyeh Haji Abolhasan Memar, Mojgan Farshadi, Parvin Afsar Kazerooni, Maryam Sargolzaeemoghaddam, Reza Majdzadeh

“…Conclusions NGOs’ participation in HIV prevention can facilitate the alignment of interventions with the specific needs of at-risk populations. However, there are obstacles to full NGOs’ participation from both NGO and government perspectives, necessitating several measures to address these challenges. …”
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Prevalence, Incidence and Predictors of Anal HPV Infection and HPV-Related Squamous Intraepithelial Lesions in a Cohort of People Living with HIV by Margherita Sambo, Alessandra Bailoni, Federico Mariani, Massimo Granai, Natale Calomino, Virginia Mancini, Anna D’Antiga, Francesca Montagnani, Mario Tumbarello, Stefano Lazzi, Franco Roviello, Massimiliano Fabbiani

“…The early detection of HPV infections and improvement of effective screening programmes are, therefore, essential to prevent progression from pre-cancerous lesions to SCC, especially in people living with HIV (PLWH), who represent a population at higher risk of HPV infection and associated lesions. …”
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Serological Profile of Anti-<i>Toxoplasma gondii</i> Antibodies in Liver Transplant Recipients by Gabriella Beltrame Pintos, Francielly Camilla Bazílio Laurindo Pires, Nathália Zini, Rita Cássia Martins Alves da Silva, Francisco Inaldo Mendes Silva Junior, Renato Ferreira da Silva, Tainara Souza Pinho, Luiz Carlos de Mattos, Cinara Cássia Brandão

“…<i>Toxoplasma gondii (T. gondii)</i>, a globally distributed obligatory intracellular opportunistic parasite that has infected one third of the world population, has different transmission routes including via organ transplantation. …”
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Revealing the biological features of the axolotl pancreas as a new research model by Hui Ma, Hui Ma, Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei, Jifeng Fei, Jifeng Fei

“…To assess pancreatic gene function, Pdx1 mutants were generated using CRISPR/Cas9-mediated gene editing, and their effects on pancreatic morphology, endocrine cell populations, and glucose homeostasis were analyzed.ResultsThe axolotl pancreas contains all known pancreatic cell types and develops from dorsal and ventral buds. …”
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Validity, reliability and clinical utility of ASSIST-Y in assessing risk of substance-related harm and dependence in Spanish male adolescents by Núria Ibáñez-Martínez, Matthew William Richard Stevens, Núria Civit-Bel, Noemí Moreno-Ferrer, Sandra Lopez-Ferré, Ana Olivares-Casado, Juame Claramunt-Mendoza, Chris Holmwood, Robert Ali

“…While the instrument was found to be valid and reliable in identifying risky use across a variety of substances, further research is needed to validate the instrument in other population groups, and for other substances. Future research should investigate the effect of the linked brief intervention to reduce risk of harm, especially for non-specialist clinicians.…”
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Classification and diagnosis of cervical lesions based on colposcopy images using deep fully convolutional networks: A man-machine comparison cohort study by Binhua Dong, Huifeng Xue, Ye Li, Ping Li, Jiancui Chen, Tao Zhang, Lihua Chen, Diling Pan, Peizhong Liu, Pengming Sun

“…Moreover, image-based and population-based diagnostic performances of the AI algorithm and physicians with different levels of specialist experience were compared. …”
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Culturally appropriate terminologies in health research: a participatory study with pregnant and breastfeeding mothers in Uganda by Ritah Nakijoba, Adelline Twimukye, Josephine Bayigga, Aida N. Kawuma, Simon Peter Asiimwe, Fredrick Byenume, Jacqueline Kyeyune, Sylvia Nabukenya, Francis Williams Ojara, Francis Williams Ojara, Catriona Waitt, Catriona Waitt

“…The use of alienating language may present a barrier for research participants hence the need to identify accurate, respectful, relevant, and acceptable terms for respective study populations. The study explored commonly used terminologies during research involving pregnant and lactating mothers using public engagement and participatory approaches in Uganda.MethodsA cross-sectional qualitative study was conducted in August 2023 among 5 ethnically diverse communities with different languages and from different regions across Uganda. …”
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Impact of using time-averaged exposure metrics on binary endpoints in exposure-response analyses by Yu-Wei Lin, Yu-Wei Lin, Yu-Wei Lin, Yu-Wei Lin, Yu-Wei Lin, Anna Largajolli, Anna Largajolli, A. Yin Edwards, A. Yin Edwards, S. Y. Amy Cheung, S. Y. Amy Cheung, Kashyap Patel, Stefanie Hennig, Stefanie Hennig

“…Here we used a modified model based on a real data example for simulating exposures and events (safety) in different virtual population sizes (n = 50, 100, or 200) and drug effect magnitudes (0.5, 0.75, or 1). …”
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