Risk of adverse cardiovascular events based on common genetic variants in 8-year follow-up of the LIPIDOGEN2015 population using the polygenic risk score (PRS): study design and me... by Maciej Banach, Martyna Fronczek, Tadeusz Osadnik, Agnieszka Gach, Dominik Strapagiel, Marcin Słomka, Mateusz Lejawa, Anna Goc, Ewa Boniewska-Bernacka, Anna Pańczyszyn, Gregory Y.H. Lip, Dimitri P. Mikhailidis, Peter P. Toth, Peter E. Penson, Jacek Jóźwiak

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Benchmarking Alzheimer’s disease prediction: personalised risk assessment using polygenic risk scores across various methodologies and genome-wide studies by Eftychia Bellou, Woori Kim, Ganna Leonenko, Feifei Tao, Emily Simmonds, Ying Wu, Niklas Mattsson-Carlgren, Oskar Hansson, Michael W. Nagle, Valentina Escott-Price, the Alzheimer’s Disease Neuroimaging Initiative

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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults by Salahuddin Mohammad, Mélissa Gentreau, Manon Dubol, Gull Rukh, Jessica Mwinyi, Helgi B. Schiöth

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Cancer, genetic susceptibility and risk of coronary artery disease: A prospective study by Yidan Wang, Shan Zhong, Na Sun, Yunfei Wu, Jun Lyu, Minghui Piao, Wenbo Qu, Xueyu Wang, Wenjun Ni, Xia Gu, Tianshu Han, Jinwei Tian

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Socioeconomic disadvantage and polygenic risk of overweight in early and mid-life: a longitudinal population cohort study spanning 12 yearsResearch in context by Jessica A. Kerr, Dorothea Dumuid, Marnie Downes, Katherine Lange, Meredith O'Connor, Ty Stanford, Lukar Thornton, Suzanne Mavoa, Kate Lycett, Tim S. Olds, Ben Edwards, Justin O'Sullivan, Markus Juonala, Ha N.D. Le, Richard Saffery, David Burgner, Melissa Wake

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Effects of the Interaction Between Oxidative Balance Score and Polygenic Risk Scores on Incidence of Metabolic Syndrome in Middle-Aged Korean Adults by Minyeong Kim, Dayeon Shin

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Relationships between the Planetary Health Diet Index, its food groups, and polygenic risk of obesity in the CARTaGENE cohort by Guiomar Masip, Daiva E. Nielsen

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Nature or nurture: genetic and environmental predictors of adiposity gain in adultsResearch in context by Laia Peruchet-Noray, Niki Dimou, Reynalda Cordova, Emma Fontvieille, Anna Jansana, Quan Gan, Marie Breeur, Hansjörg Baurecht, Patricia Bohmann, Julian Konzok, Michael J. Stein, Christina C. Dahm, Nuno R. Zilhão, Lene Mellemkjær, Anne Tjønneland, Rudolf Kaaks, Verena Katzke, Elif Inan-Eroglu, Matthias B. Schulze, Giovanna Masala, Sabina Sieri, Vittorio Simeon, Giuseppe Matullo, Esther Molina-Montes, Pilar Amiano, María-Dolores Chirlaque, Alba Gasque, Joshua Atkins, Karl Smith-Byrne, Pietro Ferrari, Vivian Viallon, Antonio Agudo, Marc J. Gunter, Catalina Bonet, Heinz Freisling, Robert Carreras-Torres

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Linking obesity-associated genotype to child language development: the role of early-life neurology-related proteomics and brain myelinationResearch in context by Jian Huang, Jinyi Che, Michelle Z.L. Kee, Ai Peng Tan, Evelyn C. Law, Patricia Pelufo Silveira, Irina Pokhvisneva, Sachin Patel, Keith M. Godfrey, Lourdes Mary Daniel, Kok Hian Tan, Yap Seng Chong, Shiao-Yng Chan, Johan G. Eriksson, Dennis Wang, Jonathan Yinhao Huang

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Alzheimer's polygenic hazard score in SuperAgers: SuperGenes or SuperResilience? by Barbara E. Spencer, Sarah J. Banks, Anders M. Dale, James B. Brewer, Beth Makowski‐Woidan, Sandra Weintraub, M.‐Marsel Mesulam, Changiz Geula, Emily Rogalski

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The role of candidate genetic polymorphisms in covid-19 susceptibility and outcomes by Anthony Yazbeck, Reem Akika, Zainab Awada, Nathalie K. Zgheib

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Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction by Kristia Yiangou, Nasim Mavaddat, Joe Dennis, Maria Zanti, Qin Wang, Manjeet K. Bolla, Mustapha Abubakar, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Adinda Baten, Sabine Behrens, Marina Bermisheva, Amy Berrington de Gonzalez, Katarzyna Białkowska, Nicholas Boddicker, Clara Bodelon, Natalia V. Bogdanova, Stig E. Bojesen, Kristen D. Brantley, Hiltrud Brauch, Hermann Brenner, Nicola J. Camp, Federico Canzian, Jose E. Castelao, Melissa H. Cessna, Jenny Chang-Claude, Georgia Chenevix-Trench, Wendy K. Chung, NBCS Collaborators, Sarah V. Colonna, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Peter Devilee, Thilo Dörk, Alison M. Dunning, Diana M. Eccles, A. Heather Eliassen, Christoph Engel, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Olivia Fletcher, Henrik Flyger, Lin Fritschi, Manuela Gago-Dominguez, Aleksandra Gentry-Maharaj, Anna González-Neira, Pascal Guénel, Eric Hahnen, Christopher A. Haiman, Ute Hamann, Jaana M. Hartikainen, Vikki Ho, James Hodge, Antoinette Hollestelle, Ellen Honisch, Maartje J. Hooning, Reiner Hoppe, John L. Hopper, Sacha Howell, Anthony Howell, ABCTB Investigators, kConFab Investigators, Simona Jakovchevska, Anna Jakubowska, Helena Jernström, Nichola Johnson, Rudolf Kaaks, Elza K. Khusnutdinova, Cari M. Kitahara, Stella Koutros, Vessela N. Kristensen, James V. Lacey, Diether Lambrechts, Flavio Lejbkowicz, Annika Lindblom, Michael Lush, Arto Mannermaa, Dimitrios Mavroudis, Usha Menon, Rachel A. Murphy, Heli Nevanlinna, Nadia Obi, Kenneth Offit, Tjoung-Won Park-Simon, Alpa V. Patel, Cheng Peng, Paolo Peterlongo, Guillermo Pita, Dijana Plaseska-Karanfilska, Katri Pylkäs, Paolo Radice, Muhammad U. Rashid, Gad Rennert, Eleanor Roberts, Juan Rodriguez, Atocha Romero, Efraim H. Rosenberg, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Rita K. Schmutzler, Christopher G. Scott, Xiao-Ou Shu, Melissa C. Southey, Jennifer Stone, Jack A. Taylor, Lauren R. Teras, Irma van de Beek, Walter Willett, Robert Winqvist, Wei Zheng, Celine M. Vachon, Marjanka K. Schmidt, Per Hall, Robert J. MacInnis, Roger L. Milne, Paul D. P. Pharoah, Jacques Simard, Antonis C. Antoniou, Douglas F. Easton, Kyriaki Michailidou

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Genetic Determinants of Left Atrial Function Are Associated With Stroke by Oliver B. Vad, Christian Paludan‐Müller, Søren Z. Diederichsen, Emily A. McKaige, Laia M. Monfort, Pia R. Lundegaard, Litten Bertelsen, Laura Andreasen, Jesper H. Svendsen, Morten S. Olesen

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Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer by Vincent Carbonnier, Julie Le Naour, Thomas Bachelot, Erika Vacchelli, Fabrice André, Suzette Delaloge, Guido Kroemer

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Interplay between lifestyle factors and polygenic risk for incident coronary heart disease in a large multiethnic cohort by Carlos Iribarren, Meng Lu, Martha Gulati, Nathan D. Wong, Roberto Elosua, Jamal S. Rana

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Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening by Georgina L Hollitt, Mark M Hassall, Owen M Siggs, Jamie E Craig, Emmanuelle Souzeau

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Commentary: Relationships between screen time and childhood attention deficit hyperactivity disorder: a Mendelian randomization study by Nagahide Takahashi, Nagahide Takahashi, Nagahide Takahashi, Kenji J. Tsuchiya, Kenji J. Tsuchiya

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Shared genetic architecture and bidirectional clinical risks within the psycho-metabolic nexusResearch in context by Xiaonan Guo, Yu Feng, Xiaolong Ji, Ningning Jia, Aierpati Maimaiti, Jianbo Lai, Zheng Wang, Sheng Yang, Shaohua Hu

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Investigating the effect of polygenic background on epilepsy phenotype in ‘monogenic’ familiesResearch in context by Karen L. Oliver, Ingrid E. Scheffer, Colin A. Ellis, Bronwyn E. Grinton, Samuel F. Berkovic, Melanie Bahlo, Zaid Afawi, Dina Amrom, Eva Andermann, Jocelyn F. Bautista, Susannah T. Bellows, Judith Bluvstein, Gregory D. Cascino, Seo-Kyung Chung, Patrick Cossette, Sarah W. Curtis, Norman Delanty, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Catharine Freyer, Micheline Gravel, Rebekah V. Harris, Erin L. Heinzen, Olivia J. Henry, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rebecca Loeb, Daniel H. Lowenstein, Anthony G. Marson, Heather C. Mefford, Paul V. Motika, Terence J. O'Brien, Ruth Ottman, Juliann M. Paolicchi, Slave Petrovski, William O. Pickrell, Mark I. Rees, Lynette G. Sadleir, Jerry J. Shih, Rani K. Singh, Michael C. Smith, Philip E.M. Smith, Rhys H. Thomas, Judith Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer

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Patient Perspectives on Personalized Risk Communication Using Polygenic Risk Scores to Inform Colorectal Cancer Screening Decisions by Shauna R. Goldberg, MPH, Linda K. Ko, PhD, Li Hsu, PhD, Hang Yin, MS, Charles Kooperberg, PhD, Ulrike Peters, PhD, MPH, Andrea N. Burnett-Hartman, PhD, MPH

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