The Clinical Pharmacokinetics and Pharmacodynamics of Glimepiride—A Systematic Review and Meta-Analysis by Mubara Azhar, Mohammed S. Alasmari, Ammara Zamir, Hamid Saeed, Faleh Alqahtani, Tanveer Ahmad, Muhammad Fawad Rasool

Get full text

Knowledge, Attitude, and Food Safety Practices among Street Food Vendors at a Metropolitan District in Ghana: A Cross-sectional Study by Abraham Norman Nortey, Hubert Amu, Ebenezer Senu, Alfred Effah

“…Street food is a vital component of cities and towns in developing countries. However, food poisoning has been associated with inadequate knowledge of food safety practices and inappropriate food handling. …”
Get full text

AcfA Regulates the Virulence and Cell Envelope Stress Response of <i>Vibrio parahaemolyticus</i> by Huan Liu, Huayu Lei, Juanjuan Cao, Zhaobang Xie, Yile Shi, Yanni Zhao

“…<i>Vibrio parahaemolyticus</i> is a ubiquitous inhabitant of estuarine and marine environments that causes vibriosis in aquatic animals and food poisoning in humans. Accessory colonizing factor (ACF) is employed by <i>Vibrio</i> to assist in the colonization and invasion of host cells leading to subsequent illnesses. …”
Get full text

Hubungan Lama Penggunaan Obat Anti Nyamuk Bakar dengan Kadar Kolinesterase Darah pada Masyarakat Kelurahan Jati Rumah Gadang Padang by Amelia ., Yustini Alioes, Sofina Rusdan

“…The conclusion of this research is the society whom used anti mosquito fuel it risked getting poisoned.<br />Keywords: anti mosquito fuel, cholinesterase, insecticide</p>…”
Get full text

The investigation of toxicokinetics parameters of cyanide and thiocyanate in mice by Sadettin Tanyıldızı, İbrahim Pirinçci, Sezai Kaya, Bünyamin Traş, Ender Yersan

“…The purpose of this study was to determine the some toxicokinetic parameters of cyanide and thiocyanate in mice experimentally poisoned with sodium cyanide. In the study, 200 mice, 40-50 g weights, were used. …”
Get full text

Blood Lead Levels among Blood Donors and High-Risk Occupational Groups in a Mining Area in Ghana: Implications for Blood Transfusion among Vulnerable Populations by Veronica Agyemang, Joseph K. Acquaye, Samuel B. E. Harrison, Felix B. Oppong, Stephany Gyaase, Kwaku P. Asante, Edeghonghon Olayemi

“…Lead poisoning has been a major global health problem for decades, and blood transfusion has been suspected as a neglected potential source of lead exposure. …”
Get full text

The investigation of sodium nitrite effects on the toxicokinetics of cyanide and thiocyanate by Sadettin Tanyıldızı, İbrahim Pirinçci, Sezai Kaya, Emine Baydan

“…This study was carried out to determine the effects of sodium nitrites on some toxicoklnetic parameters of cyanide and thiocyanate in sheep experimentally poisoned with amygdalin In this study, 18 sheep 50 &#8212; 60 kg weights were used. …”
Get full text

Imprint of ancestral and modern threats in human mind – experience of fear, disgust, and anger by Eva Landová, Eva Landová, Jakub Polák, Jakub Polák, Markéta Janovcová, Iveta Štolhoferová, Šárka Peterková, Aleksandra Chomik, Daniel Frynta

“…Here we ask whether the BIS has adapted to protect us from pandemic risks or poisoning by modern toxic substances.MethodsWe have developed a survey comprised of 60 vignettes describing threats evoking fear and disgust belonging to one of the three main categories of threats: (1) ancestral, (2) modern, and (3) pandemic of airborne disease. …”
Get full text

Strategic management of nano-fertilizers for sustainable rice yield, grain quality, and soil health by Bignyan Ranjan Sahoo, Ashish Kumar Dash, Kiran Kumar Mohapatra, Shraddha Mohanty, Suman G. Sahu, Bidwan Ranjan Sahoo, Meenakhi Prusty, Elora Priyadarshini

“…Conventional fertilizers, although widely available, are relatively low in nutrient use efficiency and cause serious environmental concerns like eutrophication, greenhouse gas (GHG) emissions, nitrate poisoning, and soil pollution. With this in mind, a randomized block design (RBD) experiment was conducted in an experimental field taking 10 treatments and 3 replications to investigate the effects of integrated approaches of nano-formulated DAP fertilizer applications on rice growth, yield, and nutrient use efficiency over conventional approaches. …”
Get full text

Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Therefore, it is possible to conclude that CLO protects rats from inflammation, apoptosis, and hepatorenal oxidative damage caused by Cd poisoning. Comprehensive translational research is required to validate CLO’s efficacy and safety of use in humans. …”
Get full text

Pancreatic cancer cell-intrinsic transglutaminase-2 promotes T cell suppression through microtubule-dependent secretion of immunosuppressive cytokines by Anton Wellstein, Thomas Seufferlein, Alexander Kleger, Tim Eiseler, Anton Lahusen, Nora Minhöfer, Kim-André Lohse, Christine Blechner, Jessica Lindenmayer, Sabine Windhorst, Yuan-Na Lin

“…Also, pretreatment of TGM2high PDOs with sublethal doses of the spindle poisons paclitaxel or vincristine increased CD8+T cell activation and sensitized PDOs toward T cell-mediated cytotoxicity.Conclusions These findings indicate that targeting microtubular function therapeutically may enhance antitumor T cell responses by impacting activity of immunosuppressive cytokines in the PDAC microenvironment.…”
Get full text

Comparison of clinical and virological features in pediatric and adult dengue cases at Insein General Hospital during Myanmar’s 2022 dengue season by Htin Lin, Mya Myat Ngwe Tun, Yin Mon Wint Zin, Khin Theingi Myint, Win Kay Khine, Khine Mya Nwe, Aye Aye Thant, Thin Thin Shwe, Win Mar, Khin Sandar Aye, Khaing Moe Aung, Yuki Takamatsu, Wah Wah Aung, Yi Yi Kyaw, Takeshi Urano, Kouichi Morita, Hlaing Myat Thu

“…Seven adult dengue cases (25%) also had other diseases including advanced HIV infection, severe pneumonia, tonsillitis, thyroid disease, cholecystitis, drug poisoning, and thalassemia. Conclusion The serotype distribution and clinical presentations of pediatric and adult dengue cases were not significantly different, but adults were more likely to have dengue together with other diseases than children. …”
Get full text

Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database by Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo

“…For signals of ivosidenib, the most frequently reported were “gastrointestinal disorders,” “general disorders and administration site conditions,” and “injury, poisoning and procedural complications.” Ivosidenib was the only IDH inhibitor with signals in “cardiac disorders.” …”
Get full text

Inpatient autopsy rate and associated factors in a Chinese megacity: a population-based retrospective cohort study by Yu Wang, Jiming Zhu, Zihan Wang, Dachun Zhao, Hange Li, Yanrong He, Xidong Guo, Hanbo Zhang, Huatang Zeng

“…The autopsy decision was significantly and positively associated with being married (OR= 1.60, 95% CI: 1.16 to 2.21), self-paying (OR=1.56, 95% CI: 1.07 to 2.26), death due to external causes of injury and poisoning (OR=1.69, 95% CI: 1.02 to 2.81) and pregnancy (OR=13.58, 95% CI: 4.94 to 37.36), but negatively associated with age (OR=0.97, 95% CI: 0.96 to 0.98), emergency admission (OR=0.66, 95% CI: 0.49 to 0.88), referral (OR=0.47, 95% CI: 0.25 to 0.88), neoplasms (OR=0.35, 95% CI: 0.22 to 0.56), respiratory diseases (OR=0.49, 95% CI: 0.26 to 0.95) and for-profit hospitals (OR=0.45, 95% CI: 0.23 to 0.91). …”
Get full text

Cadmium and lead uptake by wild swamp eel in the populous river by N. Nurhasanah, L. Sulistyowati, E. Riani, M. Cordova

“…However, cadmium and lead are poisonous and classified as cancer-causing non-essential elements. …”
Get full text

Preparation of Mo2C/MWCNT catalysts and its performance in electrocatalytic oxidation of methanol by Leixin MAO, Lin FU, Lei LIU, Zhihua GAO, Wei HUANG, Zhijun ZUO

“…The current commercial catalysts are mainly made of precious metals, and their commercialization is severely restricted by the high price, complicated preparation process, and susceptibility to intermediate poisoning. Carbides of Mo exhibit catalytic activities similar to those of noble metals due to their unique d-band electronic structures. …”
Get full text

A modified screening protocol for ARDS in patients with respiratory support based on SpO2 and FiO2: A single-center prospective, observational study by Yan Xia, Qiancheng Xu, Zhiyuan Guo, Huijuan Zhang, Yingya Cao, Yupeng Qi, Qun Chen, Weihua Lu

“…Patients with contraindications to arterial puncture, methemoglobinemia, carbon monoxide poisoning, and other factors that could affect data collection were excluded. …”
Get full text

Molecular mechanisms of aflatoxin neurotoxicity and potential neuroprotective agents by Chongshan Dai, Erjie Tian, Hui Li, Subhajit Das Gupta, Zhihui Hao, Zhanhui Wang, Tony Velkov, Jianzhong Shen

Get full text

Pengaruh Pemberian Ekstrak Rosella (Hibiscus sabdariffa Linn) Terhadap Kadar Malondialdehid dan Aktivitas Katalase Tikus yang Terpapar Karbon Tetraklorida by Zuraida , Eti Yerizel, Eliza Anas

“…<br />Kata kunci: karbon tetraklorida, MDA, katalase, rosella</p><p> </p><p>Abstract <br />Administering roselle (Hibiscus sabdariffa Linn) is expected to protect rat liver from damage caused by oxidative stress in CCl4 poisoning. Rosella contains vitamin C, flavonoids, polyphenol and beta carotene. …”
Get full text

Association Between Adolescent Violence Exposure and the Risk of Suicide: A 15-Year Study in Taiwan by Chieh Sung, Chi-Hsiang Chung, Chien-An Sun, Chang-Huei Tsao, Daphne Yih Ng, Tsu-Hsuan Weng, Li-Yun Fann, Fu-Huang Lin, Wu-Chien Chien

“…Among adolescents who had experienced violence, the methods of suicide included poisoning (solid and liquid) (53.6% vs. 43.2%), hanging (1.2% vs. 0.6%), firearms (2.4% vs. 0%), and cutting instruments (27.4% vs. 22.8%), all of which were significantly higher than in the control group. …”
Get full text