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221
Nanocellulose Targets Regenerative Medicine
Published 2025-02-01“…Of particular interest is the in vitro culture of pluripotent stem cells, which has led to a growing demand for animal-free media and scaffolds in stem cell culture. …”
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222
Renal immature teratoma in infant: A rare case report
Published 2025-03-01“…Renal teratoma is a rare malignant tumour originating from pluripotent cells. A five-month-old female presented with a painless abdominal mass initially suspected to be a Wilms tumor. …”
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223
Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure
Published 2025-02-01“…Abstract Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across developmental lineages. …”
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224
Oncogenic PIK3CA corrupts growth factor signaling specificity
Published 2024-12-01“…Dose-dependent expression of PIK3CA H1047R in human cervical cancer and induced pluripotent stem cells corrupted the fidelity of growth factor-induced information transfer, with preferential amplification of epidermal growth factor receptor (EGFR) signaling responses compared to insulin-like growth factor 1 (IGF1) and insulin receptor signaling. …”
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225
The Urodele Limb Regeneration Blastema: The Cell Potential
Published 2010-01-01“…The developmental potential of the limb regeneration blastema, a mass of mesenchymal cells of mixed origins, was once considered as being pluripotent, capable of forming all cell types. Now evidence asserts that the blastema is a heterogeneous mixture of progenitor cells derived from tissues of the amputation site, with limited developmental potential, plus various stem cells with multipotent abilities. …”
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226
Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols
Published 2017-01-01“…Here, we reviewed the current reprogramming of somatic cells using specific factors to induced pluripotent stem (iPS) cells capable of repairing islet β cell damage in diabetes patients to treat patients with type 1 diabetes mellitus. …”
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227
Generation of an isogenic series of genome-edited hiPSC lines with the BAG3P209L-mutation for modeling myofibrillar myopathy 6
Published 2025-02-01“…For quality control, we tested the pluripotency of these hiPSC lines and their ability to differentiate into the three germ layers. …”
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228
Florid Proliferation of Hyalinized Vessels in a Spermatic Cord STAT6 Positive Solitary Fibrous Tumor and Its Potential Clinical Implications
Published 2018-01-01“…We also summarize our current understanding of the structural and molecular features that make up SFTs and discuss how these features may help us better understand the pathophysiology of pluripotent mesenchymal stem cell differentiation.…”
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229
Emerging Stem Cell Therapies: Treatment, Safety, and Biology
Published 2012-01-01“…The discovery of induced pluripotent stem cells has led to an improved understanding of the underlying epigenetic keys of pluripotency and carcinogenesis. …”
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230
Laryngeal Synovial Sarcoma: A Rare Clinical Entity
Published 2013-01-01“…Synovial sarcomas (SS) are aggressive malignant soft tissue tumours that are thought to arise from pluripotent mesenchymal cells. Clinical Report. A 20-year-old male presented with an acute onset of respiratory stridor. …”
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231
Current Development of Mesenchymal Stem Cell-Derived Extracellular Vesicles
Published 2025-01-01“…Mesenchymal stem cells (MSCs) are pluripotent stem cells with self-renewal. They play a critical role in cell therapy due to their powerful immunomodulatory and regenerative effects. …”
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232
Role of the TGF-β cytokine and its gene polymorphisms in asthma etiopathogenesis
Published 2025-01-01“…Transforming growth factor beta (TGF-β) is a pluripotent cytokine expressed by all cells of the human body which plays important roles in maintaining homeostasis and allowing for proper individual development. …”
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233
Cell Therapy for Retinal Dystrophies: From Cell Suspension Formulation to Complex Retinal Tissue Bioengineering
Published 2019-01-01“…The different cell sources proposed for cell therapy including human pluripotent stem cells are presented with their advantages and limits. …”
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234
Organoid Models for Salivary Gland Biology and Regenerative Medicine
Published 2021-01-01“…Organoid cultures provide an alternative system to recapitulate salivary gland tissue in vitro, and salivary gland organoids have been generated from pluripotent stem cells and adult stem/progenitor cells. …”
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235
Mesenchymal Stem and Progenitor Cells in Regeneration: Tissue Specificity and Regenerative Potential
Published 2017-01-01“…The potential use of embryonic stem cells and invention of induced pluripotent stem cells raised hope for clinical regenerative purposes; however, the use of these interventions for regenerative therapy showed its dark side, as many health concerns and ethical issues arose in terms of using these cells in clinical applications. …”
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236
Insights into the signal transduction pathways of mouse lung type II cells revealed by transcription factor profiling in the transcriptome
Published 2019-03-01“…A transcriptional factor signature consisting of Cebpa, Srebf1, Stat3, Klf5, and Elf3 was identified in lung type II cells, Sox9+ pluripotent lung stem cells as well as in mouse lung development. …”
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237
iPSCs: A Minireview from Bench to Bed, including Organoids and the CRISPR System
Published 2016-01-01“…Ten years later, the reprogramming process became a defined method of producing induced pluripotent stem cells (iPSCs) through the overexpression of four transcription factors. iPSCs are capable of originating virtually all types of cells and tissues, including a whole new animal. …”
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238
How Does Interleukin-22 Mediate Liver Regeneration and Prevent Injury and Fibrosis?
Published 2016-01-01“…Interleukin-22 (IL-22) is a pluripotent T cell-derived cytokine which is a member of IL-10 cytokine family. …”
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239
KÖK HÜCRELER VE DİŞ HEKİMLİĞİ: LİTERATÜR DERLEMESİ
Published 2019-04-01“…Diş hekimliği alanında yetişkin mezenkimal kök hücreler çeşitli oral ve maksillofasiyal dokularda tanımlanmıştır; bu da oral dokuların kök hücrelerden zengin olduğunu ve mukozal hücrelerin indükte pluripotent kök hücreler gibi genetik olarak yeniden programlanmış hücreler için ideal kaynak olabileceğini göstermiştir. …”
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240
Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease
Published 2018-01-01“…Although the pathogenesis remains unclear, this association probably reflects an incidental and fortuitous finding rather than the alteration of a common pluripotent stem cell precursor. Herein, we report on one case of MCD coexisting with CMML and elucidate the underlying mechanism of pathology in some aspects.…”
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