Low-Intensity Light-Responsive Anticancer Activity of Platinum(II) Complex Nanocolloids on 2D and 3D In Vitro Cancer Cell Model by Viviana Vergaro, Francesca Baldassarre, Federica De Castro, Danilo Migoni, Maria Michela Dell’Anna, Piero Mastrorilli, Francesco Paolo Fanizzi, Giuseppe Ciccarella

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Recovery and Then Individual Separation of Platinum, Palladium, and Rhodium from Spent Car Catalytic Converters Using Hydrometallurgical Technique followed by Successive Precipitation Methods by Ahmed M. Yousif

“…Recovery of PGMs (especially rhodium, platinum, and palladium) from different spent manufactured products (like catalytic converters) is considered as an important task as they are rarely found in nature, and they possess high economic value. …”
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Constructing SiO2‑Supported Atomically Dispersed Platinum Catalysts with Single-Atom and Atomic Cluster Dual Sites to Tame Hydrogenation Performance by Hao Xu, Dong Lin, Jie Shi, Zhengxing Lv, Xinshuo Zhao, Linge Ning, Jiao Xiao, Lin Cui, Jian Zhang, Juncong Yuan, Xiang Feng, Yong Qin, Jiankang Zhang

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New Boric Acid Derivative with Some of Its Complexes and Study the Biological and Anticancer Activity by Alaa Abdullah Majeed, Asmaa Mohammed Noori

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Effect of Al2O3, MgO, and CuOx on the dissolution behavior of rhodium in the Na2O-SiO2 slags by Wiraseranee C., Yoshikawa T., Okabe T.H., Morita K.

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Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small Cell Lung Cancer: A Real-Life Study at a Portuguese Centre by Maria João Santos, Filipa Ferro, Andrea Machado, Ana Sofia Vilariça, Direndra Hasmucrai, Paula Alves

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Green synthesis of CuO nanoparticles from Cucurbita maxima leaf extract; a platinum free counter electrode for dye sensitized solar cells by Emma Panzi Mukhokosi, Stephen Tenywa, Nandipha L. Bothab, Shohreh Azizi, Mathapelo Pearl Seopela, Malik Maaza

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The CHK1 inhibitor prexasertib in BRCA wild-type platinum-resistant recurrent high-grade serous ovarian carcinoma: a phase 2 trial by Elena Giudice, Tzu-Ting Huang, Jayakumar R. Nair, Grant Zurcher, Ann McCoy, Darryl Nousome, Marc R. Radke, Elizabeth M. Swisher, Stanley Lipkowitz, Kristen Ibanez, Duncan Donohue, Tyler Malys, Min-Jung Lee, Bernadette Redd, Elliot Levy, Shraddha Rastogi, Nahoko Sato, Jane B. Trepel, Jung-Min Lee

“…Here we report the activity of CHK1i in platinum-resistant high-grade serous ovarian carcinoma (HGSOC) with measurable and biopsiable disease (cohort 5), or without biopsiable disease (cohort 6). …”
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Platinum drugs upregulate CXCR4 and PD‐L1 expression via ROS‐dependent pathways, with implications for novel combined treatment in gastric cancer by Xiaoyu Kang, Lin Zhang, Shushang Liu, Fei Wang, Haiming Liu, Fenli Zhou, Fei Wu, Haohao Zhang, Daiming Fan, Yongzhan Nie, Zhangqian Chen

“…However, the impact of platinum drugs, such as cisplatin, on CXCR4 or PD‐L1 expression and the underlying mechanisms in gastric cancer (GC) remain unknown. …”
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Enhanced antitumor efficacy of STING agonist MSA-2 by lipid nanoparticles delivering circular IL-23 mRNA and platinum-modified MSA-2 combination by Tian He, Yating Li, Weiqi Li, Muqing Zhang, Guishuan Wang, Peng Zhou, Guoqi Song, Wenqing Li

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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis by Shang‐Gin Wu, Chao‐Chi Ho, James Chih‐Hsin Yang, Shu‐Han Yu, Yen‐Feng Lin, Shu‐Chin Lin, Bin‐Chi Liao, Ching‐Yao Yang, Yen‐Ting Lin, Chong‐Jen Yu, Ya‐Ting Chuang, Wei‐Yu Liao, Kah Yi Yap, Weng Si Kou, Jin‐Yuan Shih

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Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation by Xuan Deng, Lu Chang, Lingyu Tang, Haoqin Jiang, Xiao Xu, Xinju Zhang, Jian Chen, Liu Dong, Qianqian Xu, Ruoshui Cao, Jianbin Xiang, Ming Guan

“…Abstract Acquired resistance poses a significant obstacle to the effectiveness of platinum-based treatment for cancers. As the most abundant antioxidant, glutathione (GSH) enables cancer cell survival and chemoresistance, by scavenging excessive reactive oxygen species (ROS) induced by platinum. …”
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Studies of the Selective Removal of Microquantities of Platinum(IV) Ions from Model Chloride Solutions onto Ion Exchangers Containing Functional Tertiary Amine and Polyamine Groups by Z. Hubicki, G. Wójcik

“…Since platinum is applied widely in industry, the recovery of noble metals from industrial wastes becomes an economic issue. …”
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Creep rupture properties of bare and coated polycrystalline nickel-based superalloy Rene®80 by Barjesteh M.M., Abbasi S.M., Zangeneh-Madar K., Shirvani K.

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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Phase II Clinical Trial by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

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Predictive value of ENLIGHT-DP in patients with metastatic lung adenocarcinoma treated with immune checkpoint inhibitors and platinum chemotherapy directly from histopathology slides using inferred transcriptomics by Eli Pikarsky, Anna Elia, Gal Dinstag, Omer Tirosh, Tuvik Beker, Ranit Aharonov, Hovav Nechushtan, Leon Gugel, Yaron Kinar, Michael Tabi, Tzivia Gottlieb, Aron Popovtzer, Johnathan Arnon, Yakir Rottenberg, Philip Blumenfeld

“…We present an analysis of ENLIGHT-DP, a novel transcriptome-based biomarker directly from histopathology slides, in patients with lung adenocarcinoma (LUAD) treated with ICI and platinum-based chemotherapy.Methods We retrospectively scanned high-resolution H&E slides from pretreatment tumor-tissue samples of 50 patients with metastatic LUAD treated with first-line ICI with (46) or without (4) platinum-based chemotherapy and applied our ENLIGHT-DP pipeline to generate, in a blinded manner, an individual prediction score. …”
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Novel platinum nanoclusters (Pt NCs) induce mitochondrial apoptosis and damaging autophagy for the treatment of osteosarcoma—from the perspective of P53 mutation status in different cell lines by Jialin Wang, Haodi Yue, Xin Huang, Hongjian Liu, Mengjun Zhang

“…Abstract This study aimed to investigate the anticancer efficacy and underlying mechanism of novel platinum nanoclusters (Pt NCs) in osteosarcoma cell lines exhibiting distinct P53 expression profiles, namely MG-63 (P53−) and U2-OS (P53+). …”
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Investigation of the optimal platinum-based regimen in the postoperative adjuvant chemotherapy setting for early-stage resected non-small lung cancer: a Bayesian network meta-analysis by Li Zhang, Wen-Feng Fang, Yi Lv, Lan-Lan Pang, Jia-Di Gan, Yi-Hua Huang, Jun Liao, Wael Abdullah-Sultan Ali

“…Objective This study aimed to compare the efficacy and safety of different platinum adjuvant chemotherapy regimens for early-stage resected non-small-cell lung cancer (NSCLC).Design Systematic review with network meta-analysis of randomised trials.Data sources PubMed, EMBASE, The Cochrane Library, Web of Science and Scopus Google Scholar were searched through 12 March 2021.Eligibility criteria Eligible randomised controlled trials (RCTs) comparing the postoperative platinum chemotherapy regimen with the observation-controlled group or comparing two platinum chemotherapy regimens head-to-head were included.Data extraction and synthesis The primary outcome was the efficacy of adjuvant chemotherapy regimens including relapse-free survival (RFS), overall survival (OS), 2-year, 3-year, 5-year RFS rate and OS rate. …”
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First-in-human phase I trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein, SL-172154 in patients with platinum-resistant ovarian cancer by Lini Pandite, Simon Metenou, Debra L Richardson, Erika Hamilton, Linda Van Le, Bo Ma, Fatima Rangwala, Nehal J Lakhani, Justin Call, Daphne Stewart, Lauren E Dockery, Guanfang Wang, Jade Huguet, Elliot Offman

“…A first-in-human phase I trial of SL-172154 was conducted in patients with platinum-resistant ovarian cancer.Methods SL-172154 was administered intravenously at 0.1, 0.3, 1.0, 3.0, and 10.0 mg/kg. …”
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New directions processing of technogenic waste of the copper industry by B. R. Vokhidov, A. S. Khasanov, B. M. Nemenenok, G. F. Mamaraimov

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