Pembrolizumab as first-line treatment for recurrent and metastatic head and neck cancer – real-world single-centre data by Bogdana Patachi, Kristian H. Jensen, Anita Gothelf, Mogens Bernsdorf, Jeppe Friborg, Claus A. Kristensen

“…Patients/material and methods: Seventy-six patients initiated treatment with pembrolizumab ± platinum/5-FU between July 2020 and May 2022. Baseline characteristics were collected, response rates and survival times were calculated and compared to those published from KEYNOTE-048. …”
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Redefining Onyx HD 500 in the Flow Diversion Era by Richard Tyler Dalyai, Ciro Randazzo, George Ghobrial, L. Fernando Gonzalez, Stavropoula I. Tjoumakaris, Aaron S. Dumont, Robert H. Rosenwasser, Pascal Jabbour

“…We report the largest US case series results using Onyx HD-500 (EV3), a new liquid embolic agent, in the successful treatment of 21 patients with wide-neck intracranial aneurysms (mean size 4.5 mm), which are at increased risk of incomplete occlusion or recanalization with standard endovascular intervention utilizing detachable platinum coils. All aneurysms were located in the anterior circulation, and three aneurysms presented as acute subarachnoid hemorrhages. …”
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Optimization of R245fa Flow Boiling Heat Transfer Prediction inside Horizontal Smooth Tubes Based on the GRNN Neural Network by Meiling Liang, Xiaohui Zhang, Rong Zhao, Xulin Wen, Shan Qing, Aimin Zhang

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Sarcopenia as a Prognostic Factor of Hepatotoxicity and Lower Survival Rate in Chemotherapy of Pancreatic Cancer by A. A. Klunichenko, A. P. Seryakov, A. A. Seryakova, S. M. Demidov

“…A retro-prospective study included 66 patients (30 men and 36 women) with locally advanced and metastatic PC receiving chemotherapy treatment in the form of gemcitabine monotherapy and in combination with platinum, taxanes, fluoropyrimidines in standard chemotherapy protocols. …”
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Treatment Options for Advanced Non-Small Cell Lung Cancer After Failure of Previous Immune Checkpoint Inhibitors and Chemotherapy: Meta-Analysis of Five Randomized Controlled Trial... by Andrea Messori, Andrea Ossato, Lorenzo Gasperoni, Luna Del Bono, Alessandro Inno, Vera Damuzzo

“…Background: Immune checkpoint inhibitors (ICIs), either alone or in combination with platinum-based chemotherapy, are effective in the first-line treatment of metastatic, non-oncogene-addicted, non-small cell lung cancer (NSCLC). …”
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Novel therapy modalities combining photodynamic therapy and liposomal cisplatin for pancreatic cancer treatments by Jia-Haur Chen, John Vincent Lim, Yih-Chih Hsu

“…Our novel study is the first original study to investigate PDT with novel lipid-platinum chloride (LPC) nanoparticles to prove the results of greater efficacy and minimal side effects. …”
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Aortic intimal sarcoma with abdominal metastasis: case report and management approach by Gongji Yao, Gongji Yao, Jianwei Xu, Jianwei Xu

“…Palliative tumor removal was performed, and the patient received chemotherapy with platinum drugs and epirubicin. Post-treatment PET-CT indicated no significant tumor staining or progression.DiscussionAortic intimal sarcoma is a rare neoplasm with limited treatment options. …”
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Bioinformation study of immune microenvironment characteristics of disulfidptosis-related subtypes in ovarian cancer and prognostic model construction by Ying Zhou, Yuhong Zhang, Yang Zhou, Yanzheng Gu, Youguo Chen, Juan Wang

“…Clinical validation showed its accuracy in predicting progression-free survival and resistance to platinum-based chemotherapy. Conclusion Our findings highlight the significant impact of disulfidptosis-related genes on the ovarian cancer tumor microenvironment, providing insights that could support the development of clinical evaluations and personalized treatment strategies.…”
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Carbon Nanofiber-Reinforced Carbon Black Support for Enhancing the Durability of Catalysts Used in Proton Exchange Membrane Fuel Cells Against Carbon Corrosion by Minki Sung, Hyeonseok Yi, Jimin Han, Jong Beom Lee, Seong-Ho Yoon, Joo-Il Park

“…The improved performance of the MEAs with the hybrid carbon support is attributed to the ability of the CNF to act as a structural backbone, facilitate water removal, and provide abundant edge plane sites for anchoring the platinum catalyst, which promoted the oxygen reduction reaction and improved catalyst utilization. …”
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Electro-Oxidation of Glycerol on Core–Shell M@Pt/C (M = Co, Ni, Sn) Catalysts in Alkaline Medium by Rudyere Nascimento Silva, Leandro Aparecido Pocrifka, Ermete Antolini, Raimundo Ribeiro Passos

“…Carbon-supported M@Pt/C (M = Co, Ni, Sn) catalysts with a 1:1 atomic ratio of metal (M) to platinum (Pt) were synthesized using a facile sodium borohydride reduction method. …”
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Exhaust gas after treatment using air preheating and selective catalytic reduction by urea to reduce NOx in diesel engine by Mohammad Shahed H.K. Tushar, Musa Ibne Mannan, Afra Azmain

“…The experimental setup involved a mechanical urea injection system, a platinum-rhodium catalyst, and an air-preheating mechanism utilizing exhaust gas heat. …”
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Experimental assessment and analysis of mass transport limiting current density in water vapor-fed polymer electrolyte membrane electrolyzers by Mary Anna Ebbert, Shawn Litster

“…To make hydrogen cost-effective, the overpotentials across the cell need to be decreased and platinum-group metal loading reduced. One overpotential that needs to be better understood is due to mass transport limitations from bubble formation within the porous transport layer (PTL) and anode catalyst layer (ACL), which can lead to a reduction in performance at typical operating current densities. …”
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Galectin-1-Dependent Mitochondria Apoptosis Plays an Essential Role in the Potential Protein Targets of DBDCT-Induced Hepatotoxicity as Revealed by Quantitative Proteomic Analyses by Jiayu Song, Yuan Ren, Lihua Liu, Yixin Wang, Chuandao Shi, Xiaoqing Ji, Yunlan Li, Qingshan Li

“…In some cases, its activity was close to or even higher than cisplatin, a first-line clinical metallic agent. Similar to platinum compounds, it also showed toxicity. However, the effective targets and mechanisms for specific toxicity and biological activity are still unclear. …”
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CD73/adenosine dynamics in treatment-induced pneumonitis: balancing efficacy with risks of adverse events in combined radio-immunotherapies by Lena Gockeln, Florian Wirsdörfer, Verena Jendrossek

“…Consolidation with PD-1/PD-L1-based immune checkpoint blockade after concurrent platinum-based chemo-radiotherapy has become the new standard of care for advanced stage III unresectable non-small cell lung cancer (NSCLC) patients. …”
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All-round enhancement induced by oxophilic single Ru and W atoms for alkaline hydrogen oxidation of tiny Pt nanoparticles by Wensheng Jiao, Zhanghao Ren, Zhibo Cui, Chao Ma, Ziang Shang, Guanzhen Chen, Ruihu Lu, Tao Gan, Ziyun Wang, Yu Xiong, Yunhu Han

“…Abstract Anion exchange membrane fuel cells (AEMFCs) are one of the ideal energy conversion devices. However, platinum (Pt), as the benchmark catalyst for the hydrogen oxidation reaction (HOR) of AEMFCs anodes, still faces issues of insufficient performance and susceptibility to CO poisoning. …”
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The role of cisplatin in modulating the tumor immune microenvironment and its combination therapy strategies: a new approach to enhance anti-tumor efficacy by Guandu Li, Xiangyu Che, Shijin Wang, Dequan Liu, Deqian Xie, Bowen Jiang, Zunwen Zheng, Xu Zheng, Guangzhen Wu

“…Cisplatin is a platinum-based drug that is frequently used to treat multiple tumors. …”
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Enhanced methanol electro-oxidation activity of CuO nanoparticles derived from the thermal decomposition of a CuII salophen type coordination compound by Zohreh Shaghaghi, Rahman Bikas, Mehri Aligholivand, Sahar Jafari, Vasyl Kinzhybalo

“…Abstract Electrocatalysts based on Cu compounds have been considered as a suitable alternative to platinum compounds due to their low cost, high abundance, excellent redox properties, and performing the methanol oxidation reaction (MOR) at low potentials. …”
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Electrochemical Detection of Iron in a Lixiviant Solution of Polluted Soil Using a Modified Glassy Carbon Electrode by D. I. Anguiano, M. G. García, C. Ruíz, J. Torres, I. Alonso-Lemus, L. Alvarez-Contreras, Y. Verde-Gómez, E. Bustos

“…The results not only revealed the modified electrode with nanotubes, polyaniline and platinum nanoparticles were the most selective and sensitive, but also provided an electroanalytic tool to analyze iron in lixiviated samples of polluted soil. …”
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Molecular Understanding of the Role of Catalyst Particle Arrangement in Local Mass Transport Resistance for Fuel Cells by Aoxin Ran, Linhao Fan, Chasen Tongsh, Jiaqi Wang, Zhengguo Qin, Qing Du, Meng Ni, Kui Jiao

“…Abstract Platinum (Pt) catalyst performance loss caused by a high local oxygen transport resistance is an urgent problem to be solved for proton exchange membrane fuel cells (PEMFCs). …”
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Dual-Source CT Angiography of Peripheral Arterial Stents: In Vitro Evaluation of 22 Different Stent Types by Michael Köhler, Matthias C. Burg, Alexander C. Bunck, Walter Heindel, Harald Seifarth, David Maintz

“…Methods and Materials. 22 stents (nitinol, steel, cobalt-alloy, tantalum, platinum alloy) were examined in a vessel phantom. …”
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