Glanzmann’s Thrombasthenia Diagnosed following Knee Arthroscopy by John E. Zvijac, Sharhabil S. Ammus, Fernando Aran, Gary M. Kiebzak

“…A hematologist was consulted and comprehensive platelet aggregation testing revealed previously undiagnosed Glanzmann’s thrombasthenia. …”
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Perbandingan Jumlah Trombosit pada Pasien COVID-19 dengan Kadar Glukosa yang Berbeda by Imanta Alifia Octavira, Agrijanti Agrijanti, Lalu Srigede, Siti Zaetun

“…Thrombocytopenia in COVID-19 patients occurs through a variety of mechanisms, such as uncontrolled production of cytokines destroying bone marrow progenitor cells, direct inhibition of hematopoiesis viral infection of the bone marrow, increase in autoantibodies and immune complexes that cause platelet destruction, and lung injury that causes platelet aggregation and consumption of platelets so that platelets in the circulation are reduced. …”
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The effect of coenzyme Q10 on the state hemostasis in the blood of old animals in high-altitude conditions by Gulbarchyn Alisherovna Asrankulova, Zhyldyz Akmatovna Makhmudova, Mahira Rysbaevna Mirzaeva, Meerim Taalaibekovna Taalaibekova, Zyinat Samidinovna Boronova, Mairambu Bektemirovna Zhorobekova

“…It was found that oral administration of coenzyme Q10 at a dose of 30 mg/kg body weight significantly reduced blood clotting time and improved platelet aggregation parameters in old rats under low- and high-altitude conditions. …”
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Subcutaneous Dorsal Penile Vein Thrombosis or Penile Mondor’s Disease: A Case Report and Literature Review by Adama Ouattara, Abdoul Karim Paré, Aristide F. Kaboré, Clotaire Yaméogo, Gnimdou Botcho, Désiré Ky, Abdoul Aziz Ouédraogo, Amidou Bako, Rigobert Kiba, Zakari Nikiéma, Timothée Kambou

“…The patient receives nonsteroidal anti-inflammatory drugs and coagulation and platelet aggregation inhibitors drugs. Healing and total recovery occur after eight weeks without any complications.…”
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Atypical Thrombotic Thrombocytopenic Purpura Presenting as Stroke by Pradeepthi Badugu, Modupe Idowu

“…In the early stages of the disease, platelet aggregation and thrombus formation may not be widespread, and thrombocytopenia and microangiopathic hemolytic anemia may not be clinically evident. …”
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Comparison of effectiveness of aspirin, clopidogrel and cilostazol monotherapy treatment in ischaemic stroke by Endarwati Tuti, Kurniasih Khamdiyah Indah, Fauziah Fauziah, Sunarti Sunarti, Agus Salim Muh.

“…Because antiplatelet medication does not improve platelet aggregation, ischemic stroke patients have significant death and disability rates. …”
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Selective Serotonin Reuptake Inhibitors and Associated Bleeding Risks: A Narrative and Clinical Review by Amber N. Edinoff, Keerthiga Raveendran, Marc A. Colon, Bennett H. Thomas, Katie A. Trettin, Grace W. Hunt, Adam M. Kaye, Elyse M. Cornett, Alan D. Kaye

“…The inhibition of serotonin reuptake can affect platelet aggregation since platelets also express the serotonin transporter. …”
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Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology by Hiroshi Ueki, I-Hsuan Wang, Maki Kiso, Kenta Horie, Shun Iida, Sohtaro Mine, Michiko Ujie, Hung-Wei Hsu, Chen-Hui Henry Wu, Masaki Imai, Tadaki Suzuki, Wataru Kamitani, Eiryo Kawakami, Yoshihiro Kawaoka

“…In the lungs of SARS-CoV-2-infected mice, increased expression of adhesion molecules in intravascular neutrophils prolonged adhesion time to the vessel wall, resulting in platelet aggregation and impaired lung perfusion. Re-analysis of scRNA-seq data from peripheral blood mononuclear cells from COVID-19 cases revealed increased expression levels of CD44 and SELL in neutrophils in severe COVID-19 cases compared to a healthy group, consistent with our observations in the mouse model. …”
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Pattern of Thrombocytopenia In Pregnancy At Teaching Hospital Of Rahim Yar Khan, Pakistan by Muhammad Bilal Ghafoor, Faiza Sarwar, Tahira Afzal Durrani, Zainab Quratulain Azher, Saleha Jabeen, Muhammad Haris Ali Khan

“…The physiological thrombocytopenia is multifactorial, related to hemodilution, increased platelet consumption and increased platelet aggregation. Objective: To determine the pattern of thrombocytopenia during third trimester of pregnancy in Rahim Yar Khan. …”
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Investigation of Interactions between Thrombin and Ten Phenolic Compounds by Affinity Capillary Electrophoresis and Molecular Docking by Qiao-Qiao Li, Yu-Xiu Yang, Jing-Wen Qv, Guang Hu, Yuan-Jia Hu, Zhi-Ning Xia, Feng-Qing Yang

“…Thrombin plays a vital role in blood coagulation, which is a key process involved in thrombosis by promoting platelet aggregation and converting fibrinogen to form the fibrin clot. …”
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Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy by Jingjing Liu, Chunyu Jiang, Xu Ma, Lishuai Feng, Jianbo Wang

“…Notoginsenoside Fc (Fc), a novel saponin isolated from Panax notoginseng, effectively counteracts platelet aggregation. Nevertheless, the potential effects and molecular mechanisms of Fc on reendothelialization have yet to be explored. …”
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Androgenic Anabolic Steroids Cause Thiol Imbalance in the Vascular Endothelial Cells by Halszka Ponamarczuk, Maria Światkowska, Marcin Popielarski

“…Conclusions: These changes may be related to a thiol-disulfide imbalance and vascular endothelium dysfunction, that are often correlated with abnormal platelet aggregation, inflammation, increased vascular permeability, and vascular smooth muscle cell proliferation—all of which are observed in athletes who abuse AASs.…”
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Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans by Ju-Sheng Zheng, Jing Yang, Tao Huang, Xiao-Jie Hu, Ming Luo, Duo Li

“…ADP-induced whole blood platelet aggregation was also significantly decreased after the intervention in both TFL and TCL groups (P<0.05). …”
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Ginkgo biloba L.: An Updated Review on the Pharmacological Activities, Pharmacokinetics and Drug Interactions by Zahra Moeinipour, Maryam Akaberi, Zahra Sobhani

“…According to the included studies, bioactive compounds found in G. biloba extract have antagonistic activity against platelet aggregation and could inhibit human thrombin, thereby increasing the risk of severe bleeding. …”
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The Influence of Inflammation on Fibrinogen Turnover and Redistribution of the Hemostatic Balance to a Prothrombotic State in High On-Treatment Platelet Reactivity-Dual Poor Respon... by Grzegorz Biolik, Dariusz Gajniak, Maciej Kubicz, Damian Ziaja, Krzysztof Ziaja, Wacław Kuczmik

“…We did not found any differences in platelet aggregation between both investigated groups, but patients who suffer from chronic inflammation presented stronger relocation of the hemostatic balance to the hypercoagulability. …”
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Effect of Antrodia camphorata on Inflammatory Arterial Thrombosis-Mediated Platelet Activation: The Pivotal Role of Protein Kinase C by Wan-Jung Lu, Shih-Chang Lin, Chang-Chou Lan, Tzu-Yin Lee, Chih-Hsuan Hsia, Yung-Kai Huang, Hsiu-Chuan Lee, Joen-Rong Sheu

“…In the present study, Antrodia camphorata treatment (56–224 μg/mL) inhibited platelet aggregation induced by collagen, but not U46619, an analogue of thromboxane A2, thrombin, and arachidonic acid. …”
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Jararaca GPIb-binding protein causes thrombocytopenia during Bothrops jararaca envenomation by Marcelo Larami Santoro, Ana Teresa Azevedo Sachetto, Jaqueline Gomes Rosa, Ricardo José Soares Torquato, Débora Andrade-Silva, Dilza Trevisan-Silva, Cynthia Zaccanini de Albuquerque, Solange M. T. Serrano, Vânia Gomes de Moura Mattaraia, Aparecida Sadae Tanaka, Maria Elisa Peichoto

“…However, neither fraction D nor fraction E induced platelet aggregation in platelet-rich plasma or whole blood from humans or mice. …”
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Preliminary Study by Differential Scanning Calorimetric Analysis of Red Blood Cells in Peripheral Artery Disease Patients Treated with Cilostazol: Correlation with Improvements in... by Dénes Lőrinczy, Dorottya Szabó, László Benkő

“…Cilostazol, a phosphodiesterase III inhibitor, has been demonstrated to enhance walking distance in patients with peripheral artery disease through the dilation of blood vessels and the inhibition of platelet aggregation. With this preliminary study, we aimed to elucidate other possible effects of cilostazol, specifically its influence on the structural properties of red blood cells. …”
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Synthesis and pharmacological properties of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione by Alexander A. Ozerov, Daria V. Merezhkina, Natalia A. Gurova, Lyudmila V. Naumenko, Denis A. Babkov, Victor S. Sirotenko, Roman A. Litvinov, Alena S. Taran, Nadezhda V. Stepanova, Umida M. Ibragimova, Alexander A. Spasov, Vadim A. Kosolapov

“…Materials and Methods: Pharmacological properties were assessed using pH-dependent platelets deformation assay, anti-inflammatory activity assay on LPS-stimulated peritoneal macrophages, antiglycation assay, analysis of platelet aggregation in vitro and measurement of intraocular pressure in vivo. …”
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The endocannabinoid system’s genetic polymorphisms in sickle cell anemia patients by Amanda Cristina Meneguetti Berti, Vanessa da Silveira Ramos de Castro, Gabriela Silva Arcanjo, Aderson da Silva Araujo, Antonio Roberto Lucena-Araujo, Marcos André Cavalcanti Bezerra, Lucas Gazarini, Danilo Grünig Humberto da Silva, Edis Belini-Júnior

“…The endocannabinoid system (ECS) could be a candidate for modulating SCA complications, such as priapism, as it has demonstrated an essential role in hematopoiesis, platelet aggregation, and immune responses. We evaluated the association of ECS-related single nucleotide polymorphisms (SNP) (FAAH rs324420, MAGL rs604300, CNR1 rs7766029, and CNR2 rs35761398) with priapism in a Brazilian SCA cohort. …”
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