The effect of SARS-CoV-2 Omicron BA. 5.2 infection on perioperative physiological indicators in orthopedic patients by Hao Wu, JunZhe Yang, YuQin Yan, Xiao Hu, BiXi Li, PengFei Cheng, XiaoYang Song

“…Changes in the following factors were compared within and between the two groups: heart rate, mean arterial pressure, oxygenation index at the time of entry into the operating room, incision of the skin and exit from the operating room and the neutrophil‒lymphocyte ratio (NLR), platelet‒lymphocyte ratio (PLR), systemic immune inflammation index (SII), D-dimer level, and fibrinogen degradation product (FDP) level. …”
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Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna... by Yuhui Guo, Chengsi Li, Haichuan Guo, Peiyuan Wang, Xuebin Zhang

“…Multivariable analysis identified traditional prognostic factors older age (OR = 1.08, 95% CI 1.04–1.12), ASA class III-IV (OR = 2.46, 95% CI 1.32–4.56), surgical delay ≥ 6 days (OR = 3.59, 95% CI 1.36–9.47), surgical duration > 180 min (OR = 2.72, 95% CI 1.17–6.35), and systemic inflammation biomarkers Platelet-to-lymphocyte ratio (PAR) ≥ 6.6 (OR = 2.25, 95% CI 1.17–4.33) and Systemic Immune-Inflammation Index (SII) ≥ 541.1 (OR = 2.24, 95% CI 1.14–4.40) as independent predictors of SSI. …”
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Advancements in Regenerative Medicine for Articular Cartilage Repair in the Management of Osteoarthritis: A Review of Modern Treatment Methods by Jakub Dziewic, Maria Przygoda, Joanna Śnieżna, Gabriela Trestka, Kamila Stępień, Sabina Adamczyk, Urszula Zelik, Wojciech Florczak, Wiktoria Domino, Jagienka Włodyka, Karol Dzwonnik

“…It focuses on the most updated treatment modalities, discussing, among other methods, microfracture, osteochondral grafts, autologous chondrocyte implantation (ACI), novel approaches of matrix-assisted autologous chondrocyte transplantation (MACT) and mesenchymal stem cell (MSC) treatments, with especial regard toward the use of platelet-rich plasma (PRP) in relation to other intra-articular injections, namely hyaluronic acid and ozone therapy. …”
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Decreased S100A9 Expression Promoted Rat Airway Smooth Muscle Cell Proliferation by Stimulating ROS Generation and Inhibiting p38 MAPK by Lei-Miao Yin, Xiao-Jie Han, Ting-Ting Duan, Yu-Dong Xu, Yu Wang, Luis Ulloa, Yong-Qing Yang

“…Decreased intracellular S100A9 expression significantly promoted platelet-derived growth factor-induced rat ASMCs proliferation and increased ROS production. …”
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The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury by Xiao Zhao, Han Han, Yinting Song, Mei Du, Mengyu Liao, Xue Dong, Xiaohong Wang, Ferenc Kuhn, Annette Hoskin, Heping Xu, Hua Yan

“…Vitreous levels of vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and plasminogen activator inhibitor-1 (PAI-1) were significantly increased in rabbit eyes after OGI. …”
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Co-administration of Hibiscus sabdariffa linn and Daflon-500® mitigates weight loss, hyperglycemia, hematological and oxidative changes in male rats with type-2 diabetes by Aishat Omobolanle Olatunji, Root Oluwapelumi Alegbe, Suleiman Folorunsho Ambali, Muftau Shittu, Ganiu Jimoh Akorede, Abdulfatai Aremu, Afisu Basiru, Jamila Abdulhamid Atata, Kolawole Yusuf Suleiman, Charles Amoto Shuaibu

“…Significantly higher packed cell volume, hemoglobin levels, red blood cell counts, lymphocytes, and mean corpuscular hemoglobin were observed in groups 5–7. Platelet counts were higher in Groups 2 and 5. Untreated group 2 exhibited considerably reduced catalase activity, glutathione, and malondialdehyde concentrations compared to the treated groups. …”
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Responsiveness and clinical utility of PROMIS instruments in pediatric Crohn's disease: insights from a longitudinal study by Sara Azevedo, Sara Azevedo, Maria Miguel Oliveira, Maria Miguel Oliveira, Paulo Nogueira, Paulo Nogueira, Paulo Nogueira, Ana Isabel Lopes, Ana Isabel Lopes

“…PCDAI scores, hemoglobin, and platelet count significantly changed and correlated with PROMIS measures. …”
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Effects of Minimally Invasive Versus Open Pancreatoduodenectomy on Short-Term Surgical Outcomes and Postoperative Nutritional and Immunological Statuses: A Single-Institution Prope... by Shinsei Yumoto, MD, Hiromitsu Hayashi, MD, PhD, Kosuke Mima, MD, PhD, Daisuke Ogawa, MD, Rumi Itoyama, MD, PhD, Yuki Kitano, MD, PhD, Shigeki Nakagawa, MD, PhD, Hirohisa Okabe, MD, PhD, Hideo Baba, MD, PhD

“…Surgical outcomes and postoperative nutritional and immunological indices (albumin, prognostic nutritional index [PNI], neutrophil-to-lymphocyte ratio [NLR], and platelet-to-lymphocyte ratio [PLR]) were examined by 1:1 propensity score matching (PSM) with well-matched background characteristics. …”
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Does hydrogen-rich water mitigate MP toxicity in rainbow trout (Oncorhyncus mykiss)? Monitoring with hematology, DNA damage, and apoptosis via ROS/GSH/MDA pathway by Atamanalp Muhammed, Kırıcı Muammer, Köktürk Mine, Kırıcı Mahinur, Alwazeer Duried, Kocaman Esat Mahmut, Ucar Arzu, Parlak Veysel, Özcan Sinan, Alak Gonca

“…In this direction, the following were determined: PP+PE chronic toxicity in aquatic organisms, the toxicity mechanism and the effect of HRW as a possible treatment method in blood tissue; with hematological indices ([RBC count [RBC], leukocyte count [WBC], hemoglobin value [Hb], hematocrit ratio [Hct], platelet count [PLT], hemoglobin count per erythrocyte [MCHC], mean hemoglobin amount per erythrocyte [MCH] and mean erythrocyte volume [MCV]) in other tissues (liver, gill and brain tissue) oxidative stress response (catalase [CAT]), glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), glutathione (GSH), reactive oxygen products (ROS), malondialdehyde ([MDA] levels), DNA damage (8-OHdG: 8-Hydroxy-2-Deoxyguanosine), and the apoptosis (caspase 3) levels were investigated. …”
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Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway by Gang Liu, Gang Liu, Bin-Bin Dong, Bin-Bin Dong, Zi-Heng Ding, Zi-Heng Ding, Chao Lan, Chang-Ju Zhu, Qi Liu, Qi Liu

“…IntroductionIn patients with acute respiratory distress syndrome, mechanical ventilation often leads to ventilation-induced lung injury (VILI), which is attributed to unphysiological lung strain (UPLS) in respiratory dynamics. Platelet endothelial cell adhesion molecule-1 (PECAM-1), a transmembrane receptor, senses mechanical signals. …”
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Risk factors and machine learning prediction models for intrahepatic cholestasis of pregnancy by Yingchun Ren, Xiaoying Shan, Gengchao Ding, Ling Ai, Weiying Zhu, Ying Ding, Fuzhou Yu, Yun Chen, Beijiao Wu

“…Through univariable and lasso regression analysis, total bile acid, gamma-glutamyl transferase, multiple pregnancy, lymphocyte percentage, hematocrit, neutrophil percentage, prothrombin time, Aspartate aminotransferase, red blood cell count, lymphocyte count and platelet count were identified as risk factors of ICP. …”
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A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine by Deepa J. Arachchillage, Golzar Mobayen, Mike Laffan, Anna M. Randi, Josefin Ahnström, Charis Pericleous

“…Methods: Cytokine-induced (tumor necrosis factor [TNF]-α, interleukin [IL]-1β, and interferon-γ) effects on ECs isolated from umbilical veins or human aortic tissue were assessed using calibrated automated thrombography in platelet-poor plasma. The expression of key coagulant and inflammatory regulators was measured at the mRNA level. …”
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Can the Risk Factors Predicting Surgical Treatment be Determined in Patients with Tubo-Ovarian Abscess? by Tayfun Vural, Burak Bayraktar, Suna Yildirim Karaca, Emir Gurbuz, Mehmet Ozeren, Cuneyt Eftal Taner

“…Patients who failed antibiotic therapy had higher infection parameters such as C-reactive protein (205±109 mg/dL vs. 115 ± 90 mg/dL, p=0.002), platelet count (349 ± 108 x 103/mm3 vs. 298 ± 95 x 103/mm3, p=0.042), and neutrophil-to-lymphocyte ratio (18.8 ± 35.7 vs. 8.2 ± 6.9, p=0.022). …”
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Microstructure, mechanical properties, thermal decomposition and oxidation sequences of crystalline AlB2 thin films by Chun Hu, Stanislav Mráz, Peter J. Pöllmann, T. Wojcik, M. Podsednik, B. Hajas, A. Limbeck, Nikola Koutná, Jochen M. Schneider, Paul H. Mayrhofer

“…Detailed transmission electron microscopy shows that the highly (0001)-oriented AlB2.27 thin film exhibits small platelet-like amorphous B regions next to the large columnar α-structured AlB2 crystals. …”
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The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Cont... by S. Abramov, S. Sokolovskyi, A. Gozhenko, I. Sobko, G. Titov, V. Gladyshev, M. Khmil, Ugis Kletnieks

“…These components can act through various mechanisms, such as inducing platelet aggregation, activating the coagulation cascade, or promoting the formation of blood clots. …”
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The Prognostic Value of CRP/Alb Ratio in Predicting Overall Survival for Hepatocellular Carcinoma Treated with Transcatheter Intra-Arterial Therapy Combined with Molecular-Targeted... by Huang X, Peng G, Kong Y, Cao X, Zhou X

“…The discriminatory capability of inflammation-based prognostic scores—including the CRP/Alb ratio, C-reactive protein and alpha-fetoprotein in immunotherapy (CRAFITY) score, modified Glasgow prognostic score (mGPS), platelet-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII)—was assessed using the area under the curve (AUC).Results: A total of 133 patients met the inclusion criteria. …”
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The value of thrombus markers applied in patients with respiratory failure by Yingqun Chen, Zihan Yin, Junshi Wang, Cunliang Yan, Xuwei Lin, Lei Huang

“…In addition, high-sensitivity C-reactive protein (hs-CRP) in the death group was higher to that in the survival group (P<0.05). Platelet count (PLT) and procalcitonin (PCT) were sharply lower in the survival group (P<0.05). …”
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MANAGING MAXILLARY BONE LOSS USING GROWTH FACTORS IN PRE-IMPLANT THERAPY by Cardas Adelina, Stratan Ion, Moraru Daliana, Tibeica Andreea, Agop-Forna Doriana, Norina Forna

“…PRGF, derived through a specific centrifugation process, concentrates essential growth factors such as Vascular Endothelial Growth Factor (VEGF), Platelet-Derived Growth Factor (PDGF), and Insulin-Like Growth Factor (IGF). …”
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Preoperative prediction of lymph node metastasis in intrahepatic cholangiocarcinoma: an integrative approach combining ultrasound-based radiomics and inflammation-related markers by Yu-ting Peng, Jin-shu Pang, Peng Lin, Jia-min Chen, Rong Wen, Chang-wen Liu, Zhi-yuan Wen, Yu-quan Wu, Jin-bo Peng, Lu Zhang, Hong Yang, Dong-yue Wen, Yun He

“…The combined model, which incorporates the optimal radiomics score, clinical N stage, and platelet-to-lymphocyte ratio (PLR), achieved an AUC of 0.882 in the validation cohort, significantly outperforming the clinical model with an AUC of 0.687 (P = 0.009). …”
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The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer by Jie Zhu, Jiale Cheng, Yuyuan Ma, Ying Wang, Zhonghua Zou, Wenjie Wang, Haihua Shi, You Meng

“…Levels of interleukin-6 (IL-6) were detected by enzyme-linked immunosorbent assays (ELISAs). Platelet-to-lymphocyte ratio (PLR) and immune inflammatory index (SII) were obtained from blood routine. …”
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