Hematological profile of pulmonary tuberculosis patients before and after 1 month of taking anti-TB drugs by Ririh Jatmi Wikandari, Surati, Siti Nuryani, Sistoyono

“…The study also found significant changes in white blood cell (p = 0.004) and platelet (p = 0.005) counts in tuberculosis patients before and after treatment. …”
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Autoimmune Factor V Deficiency That Took 16 Years to Diagnose due to Pseudodeficiency of Multiple Coagulation Factors by Takaaki Kato, Takaya Hanawa, Mea Asou, Tomohiko Asakawa, Hisashi Sakamaki, Makoto Araki

“…A coagulation abnormality with prothrombin time-international normalized ratio (PT-INR) of 4.5 and activated partial thromboplastin time (aPTT) of 99.6 seconds was observed, but the platelet count, fibrinogen, and PIVKAII were within normal limits. …”
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The associations between diet-induced inflammation and the improvement or worsening of hepatic steatosis and fibrosis: a longitudinal analysis of RaNCD cohort study by Mohammad Sedighi, Amir Saber, Amir Bagheri, Saba Hazratian, Yahya Pasdar, Farid Najafi, Mehdi Moradinazar, Davood Soleimani

“…Dietary intake was assessed using the 118-item food frequency questionnaire (FFQ), and diet-induced inflammation was determined using the dietary inflammatory index (DII). The AST to platelet ratio index (APRI) and Fibrosis-4 (FIB-4) were used as confirmed predictive indicators for hepatic fibrosis and the hepatic steatosis index (HSI) was used for hepatic steatosis. …”
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CLINICAL PROFILES OF FROSTBITE IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL: A CASE SERIES by Thomas Eduardus Sudrajat Wahyu Nugroho, Beta Subakti Nata’atmadja

“…The study found changes in platelet counts during the acute frostbite phase but no significant changes during the subacute phase following cold exposure. …”
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HEAL-Dengue: Hospital- based Exploration, Analysis and Learning about Dengue Outcomes (HEAL-D-ALDO) by Aijaz Zeeshan Khan, Omer Sabir, Adnan Hussain Shahid, Muhammad Bilal Basit, Syeda Arzinda Fatima Shah, Qamar Sajad

“…A significant association between female gender and the necessity for packed cell volume and fresh frozen plasma transfusion was observed (OR (95% CI: 10.26 (2.23 – 96.24), p =0.0005).The significant risk factors for mortality were: presence of ascites, pleural effusion, organ dysfunction, need for PCV, FFP and platelet megaunit transfusion. Higher hemoglobin on day 1 and 5 (P=0.05), higher WBCs on day 3 and 5 (p =0.0), platelets on day 5 (p =0.009), O2 saturations (p=0.0) and mean BP on presentation (p =0.008) (day 1) were significant predictors of death. …”
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Nonalcoholic Fatty Liver Disease as a Potential Risk Factor for Cardiovascular Disease in Patients with Type 2 Diabetes: A Prospective Cohort Study by Mohammad Dehghani Firouzabadi, Amirhossein Poopak, Ali Sheikhy, Fatemeh Dehghani Firouzabadi, Fatemeh Moosaie, Soghra Rabizadeh, Sara Momtazmanesh, Manouchehr Nakhjavani, Alireza Esteghamati

“…Cox regression analysis was used to assess the association between NAFLD, liver enzyme level, aspartate aminotransferase to platelet ratio index (APRI), and the incidence risk of CVD and its subgroups (i.e., myocardial infarction, chronic heart disease, coronary artery bypass grafting, and percutaneous coronary intervention). …”
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The value of common blood parameters for the differential diagnosis of respiratory tract infections in children by Jun’e Ma, Ting Tian, Nianyi Zeng, Yue Gu, Xuewei Ren, Zhengjiang Jin

“…However, common blood tests is simple and efficient, Therefore, the purpose of this study is to preliminarily distinguish Mycoplasma pneumoniae and influenza A virus infection in children by analyzing the results of common blood tests, thereby guiding clinical diagnosis and treatment.The results showed that, compared with children in the influenza A virus-positive group, children in the Mycoplasma pneumoniae-positive group had higher white blood cell (WBC), red blood cell (RBC), haemoglobin (HGB), platelet (PLT) counts, lymphocyte (LYM) and eosinophil (EOS) counts and ratios, as well as higher concentrations of C-reactive protein (CRP) and serum amyloid A (SAA), while neutrophil (NEU) and monocyte (MONO) counts and ratios, Neutrophil to Lymphocyte ratio( NLR) were lower, in addition, LYM, EOS counts and ratios, and NLR were all more effective in differentiating between the two pathogen infections, A combined analysis of these indicators further improved the differentiation efficacy. …”
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Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury by Georgios Michalettos, Fredrik Clausen, Elham Rostami, Niklas Marklund

“…Post-injury proliferation of Platelet-derived Growth Factor Receptor (PDGFRα)-positive oligodendodrocyte progenitor cells was not altered by 7,8-DHF. …”
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Clinical Outcomes and Patient Experience of Biosimilar to Biosimilar Infliximab Switching in Patients with Inflammatory Bowel Disease: A Prospective, Single-Centre, Phase IV Interv... by Clare Harris, Richard James Harris, David Young, Martin McDonnell, Bridget Clancy, Justin Harvey, Carlos Araujo, Ines Iria, Joao Goncalves, Susan Latter, J. R. Fraser Cummings

“…There was no difference in mean haemoglobin, platelet count, albumin, and C-reactive protein before and after switching. …”
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Caffeine supplement, inflammation, and hepatic function in cirrhotic patients: A randomized, placebo- controlled, clinical trial by Seyed Ali Abbas-Hashemi, Zahra Yari, Behzad Hatami, Amir Anushiravani, Shadi Kolahdoozan, Ali Zamanian, Nadia Akbarzadeh, Azita Hekmatdoost

“…Results: The results indicated a significant decrease in AST, platelets (P = 0.002), and PTT (P < 0.001), in the caffeine group compared to the placebo group. …”
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Evaluation of Tissue Homogenization to Support the Generation of GMP-Compliant Mesenchymal Stromal Cells from the Umbilical Cord by Ryan J. Emnett, Aparna Kaul, Aleksandar Babic, Vicki Geiler, Donna Regan, Gilad Gross, Salem Akel

“…To support the development of a cGMP-compliant method, we have examined an enzyme-free isolation method utilizing tissue homogenization (t-H) followed by culture in human platelet lysate (PL) supplemented media. The yield and viability of cells after t-H were comparable to those obtained after collagenase digestion (Col-D). …”
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Effect of Cell Growth and Proliferation Factors (EGF/PDGF Signaling Pathway) on the Etiopathogenesis of Intrauterine Growth Restriction by Serhan Can İşcan, Erhan Demirdağ, Melek Yaman, Emin Ümit Bağrıacık, Merih Bayram

“…Objective: It is likely that the subgroups of the epidermal growth factor/platelet-derived growth factor (EGF/PDGF) signaling pathway play a role in the etiopathogenesis of intrauterine growth restriction (IUGR). …”
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Gallic acid: a dietary metabolite’s therapeutic potential in the management of atherosclerotic cardiovascular disease by Xiao-Lan Zhao, Zhang-Jing Cao, Ke-Di Li, Fei Tang, Li-Yue Xu, Jing-Nan Zhang, Dong Liu, Cheng Peng, Hui Ao, Hui Ao

“…It alleviates the entire process of atherosclerosis (AS) by reducing oxidative stress, improving endothelial dysfunction, and inhibiting platelet activation and aggregation. Additionally, GA can treat ASCVD-related diseases, such as coronary heart disease (CHD) and cerebral ischemia. …”
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Similarities and Differences between Coronavirus Disease 2019-related Multisystem Inflammatory Syndrome in Children and Kawasaki Disease in Indian Patients by Utkarsh Singh, Suhas Prabhu, Deepak Phalgune

“…Mean white blood cell (WBC) count, percentage of lymphocytes, absolute lymphocyte count (ALC), and platelet count were notably higher in the KDG compared to the MIS-C group. …”
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A nomogram for predicting neonatal acute respiratory distress syndrome in patients with neonatal pneumonia after 34 weeks of gestation by Aosong Yu, Huanhuan Hou, Huanhuan Hou, Lingyi Ran, Xiaojia Sun, Wanchun Xin, Tong Feng

“…Gestational age, triple concave sign, blood glucose measurement after birth (Glu), Apgar score at the 5th minute (Apgar5), neutrophil count (ANC) and platelet count (PLT) are independent predictors of NARDS in late preterm and term newborns who present with progressive respiratory distress and require varying degrees of respiratory support within the first 24 h of life to minimize work of breathing and restore organismal oxygenation. …”
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Infection with Toxoplasma gondii triggers coagulation at the blood-brain barrier and a reduction in cerebral blood flow by Evelyn M. Hoover, Christine A. Schneider, Christian Crouzet, Tatiane S. Lima, Dario X. Figueroa Velez, Cuong J. Tran, Dritan Agalliu, Sunil P. Gandhi, Bernard Choi, Melissa B. Lodoen

“…Longitudinal two-photon imaging of cerebral blood vessels during infection in mice revealed vascular occlusion in the brain, prompting an analysis of the coagulation cascade. We detected platelet-fibrin clots within the cerebral vasculature during acute infection. …”
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The neutrophil percentage-to-albumin ratio is an independent risk factor for poor prognosis in peritoneal dialysis patients by Mingfan Xu, Jingjia Huan, Lujie Zhu, Jiachun Xu, Kai Song

“…Receiver Operating Characteristic (ROC) analysis indicated that the Area Under the Curve (AUC) of NPAR (0.714) was significantly superior to those of C-reactive protein (CRP) (0.597), neutrophil to lymphocyte ratio (NLR) (0.589), C-reactive protein to albumin ratio (CAR) (0.698) and platelet to lymphocyte ratio (PLR) (0.533).Conclusion NPAR served as an independent predictive marker for all-cause mortality and cardio-cerebrovascular mortality in PD patients. …”
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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…Compared with patients with PAP/SAPIPO≤0.40 (n=22), those above this level (n=18) had increased pre- and postoperative serum levels of granulocyte colony-stimulating factor (p=0.040), interleukin-1 receptor antagonist (p=0.020), interleukin-6 (p=0.003), and interleukin-21 (p=0.047) (panel for 36 human cytokines) and increased mean platelet volume (p=0.018). Using logistic regression analysis, a PAP/SAPIPO>0.40 and a heightened immediate postoperative serum level of macrophage migration inhibitory factor (quartile analysis) were shown to be predictive of significant postoperative cardiopulmonary events (respective hazard ratios with 95% CIs, 5.07 (1.10–23.45), and 3.29 (1.38–7.88)). …”
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Heparin rebound in patients undergoing off-pump coronary artery bypass grafting surgery: a single-center retrospective study by Fei Jiang, Yang Xu, Shan-shan Hu, Jin-quan Wang, Yun-tai Yao, the Evidence in Cardiovascular Anesthesia (EICA) Group

“…Results Significant differences were observed in preoperative platelet counts (P < 0.001) and the ACT measured 2 h post-heparin neutralization (P = 0.012). …”
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Iron supplementation post-blood donation in Vietnam: Impact on hemoglobin, red cell indices, and iron reserves by Viet Pham Tuan, Son Dao Anh, Phong Hoang Van, Tuan Anh Bui Sy

“…Our findings revealed moderate, statistically significant positive correlations between elemental iron administration and changes in platelet count (PLT), hematocrit (HCT), and mean corpuscular hemoglobin (MCH) (r = 0.753, p <0.001; r = 0.887, p <0.001; and r = 0.703, p <0.001, respectively). …”
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