Identifying key blood markers for bacteremia in elderly patients: insights into bacterial pathogens by Shi-Yan Zhang, Ying Zhuo, Bu-Ren Li, Ying-Ying Jiang, Jie Zhang, Na Cai, Lin Yang

“…The diagnostic efficacy of routine blood parameters, including white blood cell (WBC), neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and red blood cell distribution width (RDW), was evaluated using receive operating characteristic (ROC) curve analysis. …”
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Helicobacter pylori Eradication in Idiopathic Thrombocytopenic Purpura: A Meta-Analysis of Randomized Trials by Bum Jun Kim, Hyeong Su Kim, Hyun Joo Jang, Jung Han Kim

“…Patients in the eradication group showed significantly higher overall platelet response rate than those in the control group (odds ratio = 1.93, 95% confidence interval: 1.01–3.71, P=0.05). …”
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Successful Outpatient Management of Children at a Secondary Care Hospital in Pakistan in a Dengue Fever Epidemic and Their Clinical Outcomes by Ammara Farooq, Brekhna Aurangzeb, Taimur Khalil Sheikh, Huma Bashir, Maryam Ghuncha, Tehmina Mustafa

“…Male gender (p=0.049), lower normal mean platelet (p=0.02), and high mean hematocrit (p=0.001) were associated with disease progression. …”
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Toxicity and antioxidant assessment of ethanol leaf extract of Hibiscus surattensis in Wistar rats: hepatotoxicity evaluation by Israel Kevin Umana, Tobechukwu Anthony Tochukwu, Enoluomen Ehigiator, Chinedu Joseph Ikem, Godswill James Udom, Akinyele Olubiyi Akinsola

“…Results revealed significant rise (p<0.01-0.001) in the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), conjugated bilirubin (C.B) and total bilirubin (T.B), as well as in white blood cell (WBC) and platelet at high doses of the extract-treated rats compared to control. …”
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Eltrombopag for the treatment of refractory connective tissue disease-related thrombocytopenia: a pilot study of 52 cases by Siying Deng, Bei Wang, Ziwei Hu, Shaozhe Cai, Lingli Dong

“…The remission rates were 67.5% at month 1, 87.5% at month 2, 97.5% at month 3, and 95% at month 6. The platelet count of the patients improved significantly, with the median reaching 50 × 109/L within 2 weeks (p = 0.003). …”
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Partnering with Palliative Care: A Case Report of Severe Pain in Critical Limb Ischemia Treated Successfully with a Continuous Popliteal Nerve Catheter by Ryan S. D’Souza, Stephanie Shen, Frederick Ojukwu, Halena M. Gazelka, Bridget P. Pulos

“…In accordance with the patient’s goals of care, a continuous popliteal nerve catheter was placed, despite the high risk nature of an intervention in an immunocompromised patient with thrombocytopenia (platelet count of 30,000 platelets/microliter) and ongoing therapeutic anticoagulation. …”
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Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban by Qianxing Zhou, Florian Bea, Michael Preusch, Hongjie Wang, Berend Isermann, Khurrum Shahzad, Hugo A. Katus, Erwin Blessing

“…Thrombin not only plays a central role in thrombus formation and platelet activation, but also in induction of inflammatory processes. …”
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Analysis of MicroRNA -155-5p Expression in Patients with Primary Myelofibrosis. by Sarah I. Khaleel, Jaffar N. AlAlsaidissa

“…However, no significant correlations were found between MicroRNA-155-5p and age, sex, Janus kinase 2 mutation status, or hematological parameters, including hemoglobin, white blood cell count, and platelet count. Conclusion: MicroRNA-155-5p expression is not influenced by age, sex, Janus kinase 2 mutation status, or hematological parameters. …”
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A Comprehensive 10-Year Nationwide Pharmacovigilance Surveillance on Antibacterial Agents in Korea: Data Mining for Signal Detection of Trends and Seriousness of Adverse Events by Seon Hu Mo, Soo Hyeon Lee, Chang-Young Choi, Yongjun Sunwoo, Sooyoung Shin, Yeo Jin Choi

“…Serious events were more likely to be cardiovascular disorders (ROR 6.77, PRR 6.6, IC 2.37), urinary system disorders (ROR 5.56, PRR 5.22, IC 2.12), and platelet, bleeding, and clotting disorders (ROR 5.41, PRR 5.17, IC 2.06). …”
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Factors associated with thrombocytopenia in patients with dengue fever: a retrospective cohort study by Marcus T Silva, Luciane Cruz Lopes, Izabela Fulone, Bruna M Castilho, André R R Freitas

“…The data were identified from two databases: Notification of Injury Information System (SINAN) and Municipal Laboratory.Main outcome measure The presence of thrombocytopenia (platelet count &lt;1 50×109/L). The associations of factors that predisposed patients to thrombocytopenia and haematological changes were analysed using logistic regression. …”
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Shigella sonnei Bacteremia Presenting with Profound Hepatic Dysfunction by Oluwaseun Shogbesan, Andrew Rettew, Bilal Shaikh, Abdullateef Abdulkareem, Anthony Donato

“….), normal alkaline phosphatase, elevated total and direct bilirubin of 8.2 mg/dL and 4.4 mg/dL, albumin of 3.2 g/dL, INR of 2.9, prothrombin time of 31.7, and platelet of 96,000/μL. Workup for infectious, autoimmune and medication-induced hepatitis, Wilson’s disease, and hemochromatosis was negative. …”
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Pan-Cancer Analysis of the Prognostic and Immunotherapeutic Value of PDGFB by Bai Y, Wang X, Wang B

“…Identifying novel cancer targets is crucial to developing more effective cancer treatments. Platelet-derived growth factor-B (PDGFB) plays a critical role in various tumor processes, including angiogenesis and lymphatic metastasis. …”
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Single-center experience of venetoclax combined with azacitidine in young patients with newly diagnosed acute myeloid leukemia by Xuezhu Xu, Rui Liu, Hongli Chen, Ruoyu Yang, Gongzhizi Gao, Aili He, Fangxia Wang

“…The dependency of transfusion of red blood cell (RBC) and platelets during induction treatment was significantly lower in the VEN + AZA group (RBC: p = 0.0269; platelet: p = 0.0054). …”
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Intra-articular corticosteroids for treatment of temporomandibular joint internal disorders: protocol for systematic review and network meta-analysis by Aurelio Tobias, Daniela Torres, Carlos Zaror, Verónica Iturriaga

“…Among the minimally invasive therapies, we find the intra-articular infiltration of substances, such as corticosteroids, hyaluronic acid or platelet-rich plasma accompanied or not by an arthrocentesis. …”
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Inherited Thrombocytopenia Related Genes: GPS2 Mediates the Interplay Between ANKRD26 and ETV6 by Valeria Capaci, Melania Eva Zanchetta, Giorgia Fontana, Daniele Ammeti, Roberta Bottega, Michela Faleschini, Anna Savoia

“…Mutations in 5′UTR of ANKRD26, leading to ANKRD26-RT, disrupt this regulation, resulting in the persistent expression of ANKRD26, which leads to impaired platelet biogenesis and an increased risk of leukemia. …”
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Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association by Nupur Parakh, Kusha Sharma, Sunita Sharma, Priti Chatterjee, Varinder Singh

“…Complete blood count revealed Hb---6.7 g/dL, TLC---8.9 × 103/μL, platelet count---180 × 103/μL. Peripheral smear showed predominantly microcytic hypochromic anemia with moderate degree of anisocytosis, many nucleated red blood cells, few schistocytes, polychromatophils and corrected reticulocyte count 7.89%. …”
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Performance analysis of a wavy fin-and-tube automobile radiator operating on ethylene glycol and water based ternary nanofluids by Ferdinard Dika, Mustafa Dagbasi, Michael Adedeji, Humphrey Adun

“…TNF 1 (ZnO-Al2O3-SiO2) is made up of all spherical-shaped nanoparticles; TNF 2 (Al2O3-TiO2-MWCNT) is made up of both spherical and cylindrical nanoparticles; TNF 3 (Fe-TiO2-Graphene) comprises spherical and platelet nanoparticles; and TNF 4 (Al2O3-MWCNT-Graphene) has dissimilar-shaped nanoparticles. …”
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Thromboelastography to Monitor Clotting/Bleeding Complications in Patients Treated with the Molecular Adsorbent Recirculating System by Esther B. Bachli, Jörg Bösiger, Markus Béchir, John F. Stover, Reto Stocker, Marco Maggiorini, Eberhard L. Renner, Beat Müllhaupt, Reto A. Schuepbach

“…During MARS therapy median INR increased significantly from 1.7 to 1.9 platelet count and fibrinogen content decreased significantly from 57 fL−1 to 42 fL−1 and 2.1 g/L to 1.5 g/L. …”
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Diagnostic accuracy of systemic immune-inflammation index for acute appendicitis in the geriatric population by Ömerul Faruk Aydın, Ali Cankut Tatlıparmak

“…The SII was calculated based on neutrophil, platelet, and lymphocyte counts, and the patients were classified according to histopathological outcomes. …”
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Sequential Therapy of Linezolid and Contezolid to Treat Hematogenous Lung Abscess Caused by Staphylococcus aureus in a Congenital Cerebral Hypoplasia Patient: A Case Report by Zhou S, Xin C, Liu W

“…The patient was treated with linezolid but developed significant thrombocytopenia, so switching to sequential therapy with contezolid, the patient’s platelet counts returned to normal and his condition improved significantly.Keywords: hematogenous lung abscess, Staphylococcus aureus, linezolid, contezolid, next-generation sequencing, congenital cerebral hypoplasia…”
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