Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line by Isabella Massimi, Ambra Ciuffetta, Flavia Temperilli, Francesca Ferrandino, Alessandra Zicari, Fabio M. Pulcinelli, Maria Pia Felli

“…We found that multidrug resistance protein-4 (MRP4) overexpression has a role in reducing aspirin action in patients after bypass surgery and, very recently, we found that aspirin enhances platelet MRP4 levels through peroxisome proliferator activated receptor-α (PPARα). …”
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Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis by Xuefeng Liu, Zhiqiang Chen, Meng Yu, Wei Zhou, Xuting Zhi, Tao Li

“…Simultaneous approaches significantly promoted 1-, 3-, and 5-year disease-free survival (DFS) rates and overall survival (OS) rates, prolonged operation time, aggravated intraoperative blood loss, increased white blood cell (WBC) and platelet (PLT) counts at POD 7, and lowered total bilirubin (T-Bil) contents at POD 1 and 7. …”
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Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans by Ju-Sheng Zheng, Jing Yang, Tao Huang, Xiao-Jie Hu, Ming Luo, Duo Li

“…ADP-induced whole blood platelet aggregation was also significantly decreased after the intervention in both TFL and TCL groups (P<0.05). …”
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Protocol for assessing and visualizing cell microaggregate formation in whole blood by imaging flow cytometry by Johannes Krell, Komal Kumar Javarappa, Angie Wenedy, Andrew L. Frelinger, III, Laurent Renia, Clarissa Prazeres da Costa, Martin Schlegel, Percy Knolle, Gerhard Schneider, Oliver Hayden

“…Sample preparation artifacts, activation, and morphological changes of cells are mitigated by omitting erythrocyte lysis and leukocyte isolation while maintaining high-throughput accurate imaging of leukocytes and platelets. : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Achievement of Therapeutic Goals with Low-Dose Imiglucerase in Gaucher Disease: A Single-Center Experience by Irina Tukan, Irith Hadas-Halpern, Gheona Altarescu, Ayala Abrahamov, Deborah Elstein, Ari Zimran

“…Among 164 patients at baseline, values for spleen and liver volumes, hemoglobin and platelet counts, and Z-scores for lumbar spine and femoral were significantly different from the goal. …”
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Case report: Rituximab combined with plasma exchange treatment for systemic lupus erythematosus complicated with thrombotic microangiopathy and non-cirrhotic portal hypertension by Jinmei Huang, Wei Fan, Xuyan Chen, Shufan Wu, Zhigao Dong, Yi Zhang, Yiwan Lin, Pingping Xiao

“…Hemoglobin levels and platelet counts decreased, lactate dehydrogenase and creatinine levels increased, and the percentage of peripheral schistocytes was approximately 6.5%. …”
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Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia by Youssef Al-Tonbary, Mohammad Al-Haggar, Rasha EL-Ashry, Sahar EL-Dakroory, Hanan Azzam, Ashraf Fouda

“…Results revealed reduced chemotherapy and radiotherapy toxicity as evidenced by decreasing level of MDA, increasing level of Glu.Px and decreased occurrence of toxic hepatitis, haematological complications, and need for blood and platelet transfusions in group I compared to group II. …”
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Atypical Hemolytic Uremic Syndrome after Traumatic Rectal Injury: A Case Report by Ji-Hyoun Kang, Donghyun Lee, Yunchul Park

“…One day postoperatively, his urine output abruptly decreased and serum creatinine level increased. His platelet level decreased, and a spiking fever occurred after 2 days. …”
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Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review by Izabela Ochonska, Karolina Jaglarz, Maciej Kuca, Marcin Cholewa, Maria Jasiewicz

“…Other potential methods include scalp injections of autologous platelet-rich plasma, which contains growth factors and anti-inflammatory cytokines, and microneedling, an invasive procedure with uncertain effectiveness, especially as a standalone treatment, that aims to stimulate angiogenesis. …”
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Association between the systemic immune-inflammation index and sarcopenia in older adults: a cross-sectional study by Esra Cataltepe, Eda Ceker, Ayse Fadiloglu, Fatih Gungor, Nermin Karakurt, Zekeriya Ulger, Hacer Dogan Varan

“…To determine the SII, we used the formula: Platelet count (109/mm3)×Neutrophil count (109/mm3) / Lymphocyte count (109/mm3). …”
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Pre-probiotic effects of different bacterial species in aquaculture: behavioral, hematological and oxidative stress responses by Alak Gonca, Kotan Recep, Uçar Arzu, Parlak Veysel, Atamanalp Muhammed

“…Physiological changes in blood tissue [hematological indices: erythrocyte count (RBC), leukocyte count (WBC), hemoglobin (Hb), hematocrit (Hct), platelet count (PLT), mean cell hemoglobin concentration (MCHC), mean cell hemoglobin (MCH), and mean cell volume (MCV)], oxidative stress responses in liver and gill tissues [malondialdehyde (MDA) level, antioxidant enzyme activities: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GR), glutathione-S-transferase (GST), glucose-6-phosphate dehydrogenase (G6PD)] and acetylcholinesterase (AChE) activity in brain tissue (as neurotoxic biomarker) were investigated. …”
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An Approach to the Investigation of Thrombocytosis: Differentiating between Essential Thrombocythemia and Secondary Thrombocytosis by Ala Almanaseer, Benjamin Chin-Yee, Jenny Ho, Alejandro Lazo-Langner, Laila Schenkel, Pratibha Bhai, Bekim Sadikovic, Ian H. Chin-Yee, Cyrus C. Hsia

“…A diagnosis of ET was associated with higher hemoglobin, mean corpuscular volume (MCV), red cell distribution width (RDW), and mean platelet volume (MPV), while secondary thrombocytosis was associated with higher body mass index, white blood cells, and neutrophils (p<0.01). …”
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The Feasibility of Percutaneous Dilatational Tracheostomy in Immunosuppressed ICU Patients with or without Thrombocytopenia by Marianne Angelberger, Michaela Barnikel, Alessia Fraccaroli, Johanna Tischer, Sofía Antón, Alexandra Pawlikowski, Mark op den Winkel, Hans Joachim Stemmler, Stephanie-Susanne Stecher

“…There were no significant differences in leucocyte or platelet count on the tracheostomy day. Patients with coagulation disorders and patients under immunosuppression were distributed equally among both groups. …”
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Prediction of pulmonary embolism by an explainable machine learning approach in the real world by Qiao Zhou, Ruichen Huang, Xingyu Xiong, Zongan Liang, Wei Zhang

“…The SHAP summary plot delineated the positive and negative effects of features attributed to the RF prediction model, including D-dimer, activated partial thromboplastin time (APTT), fibrin and fibrinogen degradation products (FFDP), platelet count, albumin, cholesterol, and sodium. Furthermore, the SHAP dependence plot illustrated the impact of individual features on the RF prediction model. …”
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Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study by Ramakrishna Pai Jakribettu, Rekha Boloor, Andrew Thaliath, Sharanya Yesudasan George, Thomas George, Manoj Ponadka Rai, Umran Rafique Sheikh, Kadke Shreedhara Avabratha, Manjeshwar Shrinath Baliga

“…With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. …”
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Exploring the Dynamics of Sleep Deprivation: Insights into Complete Blood Count and Coagulation Parameters in a Case-Control Study by Abd Elhadi Agena, Leena Mirghani, Abdirasak Ali Mude

“…The difference in hemoglobin and hematocrit on day 3 was statistically significant (p=0.023). Platelet counts were stable. Both groups’ prothrombin times were unaffected. …”
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Dengue severity by serotype and immune status in 19 years of pediatric clinical studies in Nicaragua. by Federico Narvaez, Carlos Montenegro, Jose G Juarez, José Victor Zambrana, Karla Gonzalez, Elsa Videa, Sonia Arguello, Fanny Barrios, Sergio Ojeda, Miguel Plazaola, Nery Sanchez, Daniel Camprubí-Ferrer, Guillermina Kuan, Gabriela Paz Bailey, Eva Harris, Angel Balmaseda

“…DENV2 was associated with increased odds of pleural effusion and low platelet count, while DENV3 was associated with both hypotensive and compensated shock.…”
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Clinical Diagnostic Value of Quantitative Hepatitis B Virus Core Antibody Test in Chronic Viral Hepatitis B by Xi Su, Huangping Chen, Zifei Zhu, Wanying Xie, Jianqiao Peng, Xinping Ma, Wenwen Jin, Wei Shi, Zhonghua Deng, Cunyan Li

“…The quantitative detection of HBcAb, hepatitis B surface antigen (HBsAg), HBV DNA, alanine aminotransferase (ALT), aspartate aminotransferase (AST), and platelet count (PLT) were determined in the serum of 73 cases of low-replicative phase (LR), 46 cases of immune-tolerant phase (IT), 44 cases of immune clearance phase (IC), and 57 cases of HBeAg-negative hepatitis (ENH). …”
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Factors Associated with Anemia among People Living with HIV/AIDS Taking ART in Ethiopia by Ketema Bizuwork Gebremedhin, Tadesse Bedada Haye

“…Factors that were found to affect anemia among these patients include gender (OR = 2.26 [95% CI: 1.22, 4.16]), occupation (OR: 0.57 [95%CI: 0.35, 0.92]), WBC count (OR = 2.30 [95% CI: 1.29, 4.09]), platelet count (OR = 2.89 [95% CI: 0.99, 8.41]), nutritional status (OR = 2.05 [95% CI: 0.69, 6.02]), and WHO clinical stage of HIV/AIDS (OR = 3.69 [95% CI: 1.86, 7.31]). …”
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The Serum Biomarkers in Ulcerative Colitis by Semih SEZER, Selim DEMIRCI, Melisa Irem KARA, Murat KORKMAZ

“…Objective: In this study, the aim was to evaluate the diagnostic effectiveness of more easily applicable and cost-effective serum biomarkers, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein (CRP) to albumin ratio (CAR), and CRP-to-lymphocyte ratio (CLR), instead of the endoscopic activity index (EAI) used to determine disease activation in ulcerative colitis (UC) patients. …”
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