Mechanisms of Inflammation in Proliferative Vitreoretinopathy: From Bench to Bedside by Stavros N. Moysidis, Aristomenis Thanos, Demetrios G. Vavvas

“…One such target is the indirect pathway of activation of platelet-derived growth factor receptor alpha (PDGRα), which plays an important role in PVR. …”
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Pyruvate Kinase Deficiency Causing Priapism by Vinay Hanyalu Shankar, Bharadwaj Adithya-Sateesh, Nicole Gousy, Girma Ayele, Freyr Petursson, Rediet Atalay, Miriam Michael

“…While it is still unclear how splenectomies can result in thrombotic events in PKD, there does appear to be a correlation between splenectomies with resultant thrombocytosis with increased platelet adhesion.…”
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Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats by Deniz Uluışık, Ercan Keskin, Durmuş Hatipoğlu

“…At the end of the study, erythrocyte count, leukocyte count, platelet count, hemoglobin amount, hematocrit value, percentage ratios of leukocyte types, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) were determined in blood samples taken from all animals. …”
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Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence by Sashini D. Perera, Uthpala A. Jayawardena, Chanika D. Jayasinghe

“…The available evidence conclusively demonstrates the potential of E. hirta against dengue as it holds significant antiviral and platelet increasing activities. However, the number of studies conducted to validate its antidengue activity was found to be inadequate. …”
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High-dose intravenous immunoglobulin may be an efficient treatment option for patients with late-onset high-grade immune effector cell-associated hematotoxicity refractory to stand... by Yousef Laham, Shimrit Ringelstein-Harlev, Daniel Kurnik, Riva Fineman, Dana Yehudai-Ofir, Lilach Bonstein, Noga Setter-Marco, Eyal Braun, Itai Ghersin, Tsila Zuckerman, Ofrat Beyar-Katz

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Human parathyroid hormone fragment stimulates the de novo synthesis of prostaglandin endoperoxide synthase in chick calvaria by Chin-Yuh Yang, Ching-Liang Meng, Patrick Y- K. Wong

“…However, epidermal growth factor (EGF), platelet-derived activating factor (PDGF), and ionophore A23187 did not show the same stimulating effect as hPTH-(1–34) on PG synthase in calvaria. …”
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HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR PAEDIATRIC PATIENTS WITH X-LINKED LYMPHOPROLIFERATIVE SYNDROME by Yuan Sun

“…The conditioning regimens were tolerated in all seven patients, and the median time of neutrophil engraftment was 10 days (8-13 days), that of platelet engraftment was 21 days (14-24 days). STR-PCR analysis on the peripheral blood cells showed complete donor origins. …”
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A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris by Mustafa Bolatkale, Ahmet Cagdas Acara

“…The aim of this study was to investigate the predictive value of platelet-lymphocyte ratio (PLR) levels and compare with the modified heart score (m-HS) and stress testing to predict the severity of high-risk patients with unstable angina pectoris (UAP) in the ED. …”
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Blood Reference Intervals for Antillean Manatees (Trichechus manatus manatus) from Puerto Rico by Antonio A. Mignucci-Giannoni, Mayela M. Alsina-Guerrero

“…We obtained values for white blood cell count and red blood cell count, hemoglobin, hematocrit, platelet, mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration, and red cell distribution width. …”
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Sequential release of cytokines, lipid mediators and nitric oxide in experimental colitis by A. P. M. van Dijk, Z. J. Keuskamp, J. H. P. Wilson, F. J. Zijlstra

“…Then a 25% inflammation score was reached which coincided with an increased production of platelet-activating factor (PAF). No significant changes were observed in leukotriene B4 and C4 formation. …”
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Fedratinib for the treatment of myelofibrosis: a critical appraisal of clinical trial and “real-world” data by Adrian Duek, Ilona Leviatan, Osnat Jarchowsky Dolberg, Martin H. Ellis

“…Based on randomized clinical trial data, it is approved for use in patients with International Prognostic Scoring System (IPSS) or Dynamic International Prognostic Scoring System (DIPSS) intermediate-2 or high-risk disease and is distinguished from ruxolitinib in that it can be administered without dose reduction in patients with thrombocytopenia, to a platelet count above 50,000/µL. In these trials, fedratinib achieved significant spleen volume reduction in ~30–45% of patients and improvement in total symptom scores in 35–40% with good tolerability. …”
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Processing of Polypropylene-Organic Montmorillonite Nanocomposite by Equal Channel Multiangular Extrusion by V. A. Beloshenko, A. V. Voznyak, Yu. V. Voznyak, L. A. Novokshonova, V. G. Grinyov, V. G. Krasheninnikov

“…With using X-ray structure analysis, TEM, DSC, and dilatometry, it has been demonstrated that this kind of processing provides an additional intercalation of the polymer into OMMT tactoids with the succeeding exfoliation and facilitates an increase in the aspect ratio, the degree of platelet orientation, the crystalline lamellar thickness, and a decrease in the dispersion of the crystallite thickness, as well as the formation of biaxial orientation of the OMMT and PP crystals. …”
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Severe Vitamin B12 Deficiency in Pregnancy Mimicking HELLP Syndrome by Shravya Govindappagari, Michelle Nguyen, Megha Gupta, Ramy M. Hanna, Richard M. Burwick

“…Severe vitamin B12 deficiency may present with hematologic abnormalities that mimic thrombotic microangiopathy disorders such as hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. We report a patient diagnosed with severe vitamin B12 deficiency, following termination of pregnancy for suspected preeclampsia and HELLP syndrome at 21 weeks’ gestation. …”
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Tirosin Kinase Inhibitors in Chronic Graft versus Host Disease: From Bench to Bedside by Jacopo Olivieri, Sabrina Coluzzi, Imma Attolico, Attilio Olivieri

“…In many inflammatory fibrotic diseases, such as Systemic Scleroderma (SSc) and cGVHD with fibrotic features, an abnormal activation of transforming growth factor (TGFβ) and platelet-derived growth factor receptor (PDGF-R) pathways have been observed. …”
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A Case of Leptospirosis-Associated Severe Pulmonary Hemorrhagic Syndrome Successfully Treated with Venovenous Extracorporeal Membrane Oxygenation by Nao Umei, Shingo Ichiba

“…His condition continued to deteriorate, with decreasing platelet count, worsening renal function, hyperbilirubinemia, hypotension, and respiratory distress. …”
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Acute Lymphoblastic Leukemia Presenting as Pituitary Apoplexy: A Case Report and Review of the Literature by Rahul Gupta, Urmimala Bhattacharjee, K. S. Lekshmon, Shakun Chaudhary, Prashant Sharma, Aditya Jandial, Pinaki Dutta

“…The underlying pituitary adenoma was either nonfunctioning or a prolactinoma, and in majority, the apoplexy event occurred after the diagnosis of haematological malignancy. The platelet counts at the time of PA were less than 30 × 109/L in all, and the malignancy subtypes were acute or chronic myeloid leukemia and chronic lymphoid leukemia. …”
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Noninvasive Tests to Assess Liver Stiffness in Patients with Chronic Hepatitis B: APRI, FIB-4, and FIB-5 Scores by Aysun Yakut, Murat Aladag

“…“Aspartate aminotransferase (AST)-platelet ratio index” (APRI), “4 factor-based fibrosis index” (FIB-4) score, and “5 factor-based fibrosis index” (FIB-5) score were calculated and compared with liver histopathological features. …”
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Magnesium and Vascular Changes in Hypertension by Ana Rosa Cunha, Bianca Umbelino, Margarida L. Correia, Mario Fritsch Neves

“…In addition, lower concentrations of magnesium are associated with oxidative stress, proinflammatory state, endothelial dysfunction, platelet aggregation, insulin resistance, and hyperglycemia. …”
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Immune Thrombocytopenic Purpura following Administration of mRNA-Based SARS-CoV-2 and MMR Vaccinations: A Cautionary Tale by Whitney Thomas, Adam Albano, Dean Kirkel, Nason Rouhizad, Folasade Arinze

“…The patient was hospitalized briefly and treated for ITP with glucocorticoids, IVIG, and platelet transfusion. Although our patient’s clinical presentation and subsequent course are similar to those of other cases of ITP in association with SARS-CoV-2 vaccination, to our knowledge, this is the first reported case of ITP following MMR and mRNA SARS-CoV-2 vaccine coadministration. …”
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The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth by Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen

“…Proteins such as transforming growth factor (TGF), endothelin-1 (ET-1), angiotensin II (Ang II), connective tissue growth factor (CCN2/CTGF), insulin-like growth factor (IGF), and platelet-derived growth factor (PDGF) appear to act in a network that contributes to the development of gingival fibrosis. …”
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