Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients by Liu K, Yang L, Liu Y, Zhang Y, Zhu J, Zhang H, He Z

“…This study aimed to verify the predictive value of the clinical parameters such as systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) for the severity in Large Artery Atherosclerosis (LAA) stroke patients.Methods: The SII is defined as platelet × (neutrophil count/lymphocyte count), the NLR is defined as neutrophil count/lymphocyte count. …”
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Intramural pregnancy after intrauterine insemination in a nulligravid patient without previous uterine trauma, complicated by idiopathic thrombocytopenic purpura: A case report by Koyo Yamamoto, Tsuyoshi Takiuchi, Kengo Kiso, Saki Ishii, Satoshi Nakagawa, Yasuto Kinose, Michiko Kodama, Yutaka Ueda, Kenjiro Sawada, Takahiro Tsuboyama, Tadashi Kimura

“…Upon further investigation, the patient was diagnosed with idiopathic thrombocytopenic purpura, presenting with a platelet count of 30,000/μL. Due to the associated risk of hemorrhage, we proceeded with emergency exploratory laparoscopy after platelet transfusion. …”
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Impact of Granulocyte Colony-Stimulating Factor (G-CSF) on Clinical Outcomes in Allogeneic Hematopoietic Cell Transplantation: Does Speeding Up Neutrophil Engraftment Make a Differ... by Ahmed Alnughmush, MD, Ayman Sayyed, MD, Mats Remberger, PhD, Eshrak AL-Shaibani, MD, Carol Chen, BSc, Caden Chiarello, Ivan Pasic, MD, Igor Novitzky-Basso, MD, Arjun Datt Law, MD, Wilson Lam, MD, Dennis (Dong Hwan) Kim, MD, Armin Gerbitz, MD, Auro Viswabandya, MD, Rajat Kumar, MD, Fotios V. Michelis, MD, Jonas Mattsson, MD, PhD

“…This study aimed to assess the impact of granulocyte colony-stimulating factor (G-CSF) administration posttransplantation on neutrophil and platelet engraftment, incidence of bloodstream infections (BSIs), graft-versus-host disease, engraftment syndrome (ES), and survival metrics including overall survival, nonrelapse mortality, and graft-versus-host disease–free/relapse-free survival. …”
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Presumed Glenoid SLAP Tear in an Adolescent Football Player Belied the Presence of a Coracoid Growth Plate Fracture: A Diagnostic Conundrum by John G. Skedros, J. Hunter Marshall, John T. Cronin

“…Hoping to expedite his healing with platelet or stem cell injections, the parents sought an opinion from another physician who obtained a right shoulder MRI with intra-articular contrast. …”
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Eicosanoid and cytokine levels in plasma of patients during mesenteric infarction by N. Nathan, Y. Denizot, P. Feiss

“…High plasma levels of 6- keto-prostaglandin (PG) F1α (the stable metabolite of PGI2), interleukin (IL)-6 and IL-8 are observed whereas plasma tumour necrosis factor alpha (TNFα), TxB2 (the stable metabolite of TxA2), PGE2, leukotrienes (LT)B4 and LTC4, and whole blood platelet-activating factor levels are not different from values obtained in similarly severe atherosclerotic patients. …”
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Autologous Minimally Invasive Cell-Based Therapy for Meniscal and Anterior Cruciate Ligament Regeneration by Pradeep V. Mahajan, Swetha Subramanian, Siddhesh C. Parab, Sanskruti Mahajan

“…We injected autologous mesenchymal stem cells obtained from the bone marrow and adipose tissue and platelet-rich plasma into the joint of the patient at the area of injury, as well as intravenously. …”
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ABO Blood Groups and Cardiovascular Diseases by Hanrui Zhang, Ciarán J. Mooney, Muredach P. Reilly

“…Advances in our understanding of the physiologic importance of various endothelial and platelet-derived circulating glycoproteins are elucidating the mechanisms through which the ABO blood group may determine overall cardiovascular disease risk. …”
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Reenvisioning Traditional to Regenerative Therapeutic Advances in Managing Nonalcoholic Fatty Liver Disease in Diabetes Mellitus by Lung-Wen Tsai, Yi-Hsiang Lu, Rajni Dubey, Jeng-Fong Chiou

“…These cellular therapies could be further complemented by platelet-derived biomaterials, TCM formulations, or any specific drug. …”
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Turnour necrosis factor stimulates endothelin-1 gene expression in cultured bovine endothelial cells by Silvia Orisio, Marina Morigi, Carla Zoja, Norberto Perico, Giuseppe Remuzzi

“…These findings suggest that the enhanced synthesis and release of endothelin-1 occurring in conditions of increased generation of TNF, may act as a modulatory factor that counteracts the hypotensive effect and the excessive platelet aggregation and adhesion induced by TNF.…”
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Fat Graft Myringoplasty versus Chemical Cauterization in Small Tympanic Membrane Perforation:A Comparative Study by Vertika Tewari, Mohamed Tabrez Bahauddin Gafoor, Harendra Kumar Gautam, Azme Zehra, Priyali Singh

“…A variety of autografts have been used for closure of tympanic membrane perforation such as perichondrium. temporalis fascia, cartilage fat, platelet rich plasma, and chemical cauterization. …”
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Emergency Splenectomy in a patient with primary immune thrombocytopenia and hemoperitoneum by Liermis Michael Dita Salabert, José Eduardo Consuegra Díaz, Carlos Jaime Geroy

“…Primary immune thrombocytopenia is an acquired autoimmune disease, with a very variable clinical course, which causes an accelerated destruction by antibodies and an impaired platelet production. A case of a 40 year-old female patient of rural origin with a history of mitral stenosis and atrial fibrillation, diagnosed two months prior to her admission to the Dr. …”
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Ibrutinib-Associated Cardiac Tamponade with Concurrent Antiplatelet Therapy by Jennifer L. Miatech, John H. Hughes, Dillon K. McCarty, M. Patrick Stagg

“…The increased bleeding tendency associated with ibrutinib is thought to be related to its effect on several platelet signaling pathways, which can be exacerbated in the setting of concurrent antiplatelet or anticoagulant therapy. …”
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Living, Caring, Learning – Setting boundaries for the wellbeing of everyone in bleeding disorders care by Harrison Cathy

“…Cathy, a haemophilia nurse specialist in the UK, reflects on a challenging patient with a rare inherited platelet disorder. The patient did not attend regular clinic appointments, and when presenting at clinic due to severe bleeding or feeling unwell was often aggressive and abusive towards staff. …”
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Triglyceride-Glucose Index and its Relationship to Erectile Dysfunction in Subjects without Heart Disease by Sudeep Jayaram, S Santhosh, Nikhil Vaidya, Arifa Bakerywala, Harsh Anadkat, Heena Shaikh

“…Results: The examination indicated that there were no notable disparities between the two groups regarding smoking rates, alcohol intake, or measurements of high-density lipoprotein cholesterol, haemoglobin, creatinine levels, and leukocyte and platelet counts. Individuals experiencing erectile dysfunction were found to be older and exhibited significantly higher levels of total cholesterol, low-density lipoprotein cholesterol, glucose, triglycerides, and the TyG index compared to the control group. …”
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Surface Modification of Biomaterials: A Quest for Blood Compatibility by Achala de Mel, Brian G. Cousins, Alexander M. Seifalian

“…These modifications aim to modulate platelet responses directly through modulation of thrombogenic proteins or by inducing antithrombogenic biomolecules that can be biofunctionalised onto surfaces or through inducing an active endothelium. …”
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Oral liken planus hastalarında i-PRF, depo-medrol uygulamaları: Olgu serisi by Elifhan Alagöz, Tuğba Ünver, Mustafa Tunalı, Zeliha Betül Özsağır, Ebru Sağlam, Suzan Bayer Alınca

“…Bu olgu serisinde amacımız oral liken planus tedavisinde kortikosteroidlere alternatif tedavi olan i-PRF in etkinliği hakkında edindiğimiz sonuçları paylaşmaktır.Olgu Tanımlaması: Kliniğimize çift taraflı yanma ve ağrı şikayetiyle başvuran eroziv, retiküler OLP hastaların bir tarafına OLP nin altın standardı olan depo kortikosteroid, diğer tarafına injectable-platelet-rich-fibrin (i-PRF) uygulanmıştır.Bulgular: İşlem öncesi VAS değeri ile işlemlerden 2 ay sonrası VAS değeri arasında anlamlı farklılık gözlenmiştir.…”
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A Case of Essential Thrombocythemia and IgA Nephropathy with Literature Review of the Concurrence by Shoja Rahimian, Timothy Johnson, Ronald Herb

“…Improved management of such cases depends on the recognition of the combined occurrence of ET and glomerular diseases and uncovering the shared pathogenesis between platelets and glomeruli.…”
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Rapid Onset Severe Immune Thrombocytopenia following mRNA COVID-19 Vaccine in a Young Patient by Jorge Avila, Huseyin Berk Degirmenci, Pamela Contreras Chavez, Elisabeth M. Battinelli, Jorge Fleisher

“…He responded to the first-line ITP treatment with corticosteroids and intravenous immunoglobulin (IVIG) as evidenced by the fast recovery of platelet count and lack of recurrence of thrombocytopenia.…”
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An Atypical Presentation of Brucellosis in a Patient with Isolated Thrombocytopenia Complicated with Upper Gastrointestinal Tract Bleeding by Suleyman Baldane, Serdar Sivgin, Tahsin Sezgin Alkan, Fatih Kurnaz, Cigdem Pala, Muzaffer Keklik, Ahmet Karaman, Leylagul Kaynar

“…In laboratory tests, the platelet count was found to be /L. Intravenous or oral corticosteroid treatment was thought to be given for ITP but disclaimed due to upper GIS bleeding. …”
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Effects of esculentoside A on turnour necrosis factor production by mice peritoneal macrophages by Fang Jun, Zheng Qin Yue, Wang Hong Bin, Ju Dian Wen, Yi Yang Hua

“…Previous studies have showed that EsA reduced the releasing of platelet activating factor (PAF) from rat macrophages. …”
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