Effect of Bio-Electro-Magnetic-Energy-Regulation (BEMER) Horse Therapy on Cardiopulmonary Function and Recovery Quality After Isoflurane Anesthesia in 100 Horses Subjected to Pars-... by Olivier Brandenberger, Andrey Kalinovskiy, Jens Körner, Hermann Genn, Ralph Burger, Stephan Leser

“…This randomized, investigator-blinded, placebo-controlled trial evaluates equine cardiopulmonary function and recovery quality after BEMER therapy application for 15 min in 100 horses during general anesthesia using isoflurane for pars-plana vitrectomy surgery as treatment for recurrent uveitis. …”
Get full text

Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial by Liana Trugilho, Lívia Alvarenga, Ludmila Cardozo, Bruna Paiva, Jessyca Brito, Isis Barboza, Jonatas Almeida, Juliana dos Anjos, Pramod Khosla, Marcelo Ribeiro-Alves, Denise Mafra

“…Seventeen HD patients (9 in the placebo group, 8 in the TRF group) and 16 ND CKD patients (8 in the placebo group and 8 in the TRF group) completed the study. …”
Get full text

Metoprolol for prophylaxis of postoperative atrial fibrillation in cardiac surgery patients: systematic review and meta-analysis by Mohd Noor Norhayati, Muhammad Irfan, Ismail Shaiful Bahari, Sulaiman Zaharah, Nik Hussain Nik Hazlina, Zainuddin Mohammad Aimanazrul

“…Subgroup analysis and funnel plot were not performed.Conclusions Metoprolol is effective in preventing POAF compared with placebo and showed no difference with class III antiarrhythmic drugs. …”
Get full text

The Effects of C. lacerata on Insulin Resistance in Type 2 Diabetes Patients by Arim Choi, Jung Hye Kim, Hye-Kyung Chung, Chul Woo Ahn, Hee Joon Choi, Yu-Sik Kim, Ji Sun Nam

“…Subjects were randomly divided into placebo (n=45) or C. lacerata (n=45) groups and then assigned to take placebo or C. lacerata capsules (500 mg/capsule) for a 12-week intervention period. …”
Get full text

Effect of tart cherry juice on risk of gout attacks: protocol for a randomised controlled trial by Kirstie Louise Lamb, Anthony Lynn, Jean Russell, Margo E Barker

“…Participants will be randomly assigned to an intervention group, which will receive Montmorency tart cherry juice daily for a 12-month period, or a corresponding placebo group, which will receive a cherry-flavoured placebo drink. …”
Get full text

Corticosteroids in critically ill patients with community-acquired pneumonia: A systematic review and Bayesian meta-analysis by Wei Yu Chua, Natalie Chew, Shruthi C Iyer, Rachel Goh, Wei Ren Ryanna Koh, Hong Lien Vu, Qai Ven Yap, Miny Samuel, John Soong, Matthew Edward Cove

“…In ICU patients with severe CAP who were treated with corticosteroids, there was no significant reduction in hospital mortality (risk ratio [RR] 0.70, 95% confidence interval [CI] 0.39–1.14, certainty of evidence: ⊕⊕⊝⊝ low) or all-cause mortality (RR 0.68, 95% CI 0.34–1.22, ⊕⊕⊝⊝ low) compared with placebo. The use of corticosteroids showed a significant reduction in mechanical ventilation post-intervention (RR 0.58, 95% CI 0.37–0.86, ⊕⊕⊕⊕ high) compared with placebo. …”
Get full text

The efficacy of platelet rich plasma in the treatment of erectile dysfunction: a systematic review and meta-analysis of randomized controlled trials by Qiancheng Mao, Yingying Yang, Yang Liu, Hongquan Liu, Gonglin Tang, Xiaofeng Wang, Yuanshan Cui, Jitao Wu

“…Additionally, in terms of IIEF, PRP showed significantly better efficacy than placebo at the first, third, and sixth months (p < 0.00001).Conclusions PRP shows more effectiveness in treating ED compared to placebo, offering hope as a potential alternative treatment for ED.…”
Get full text

Effect of Different Kinesiotaping Techniques on Nonspecific Chronic Low Back Pain by Kristina Koch, Vilma Dudonienė, Rima Solianik

“…To determine the effects of star-shaped, “H-shaped”, and placebo kinesiology taping methods on non-specific chronic back pain, trunk mobility, static endurance of trunk muscles, and functional status in women with non-specific low back pain. …”
Get full text

A Systematic Literature Review and Bucher Indirect Comparison: Tildrakizumab versus Guselkumab by Kristian Garn Du Jardin, Pepi Hurtado Lopez, Mette Lange, Rachael McCool, Silvia Maeso Naval, Sandra Quickert

“…Limitations included the limited number of publications, imputation of placebo arm values for Weeks 24 to 28, and limited relevance of the Japanese study. …”
Get full text

A pooled analysis of the efficacy of sertraline in women, with a focus on those of childbearing age by Andrea Fagiolini, Melissa Paulita Mariano, Egbert Biesheuvel, Pradeep Purushottamahanti

“…Sertraline was compared with placebo for changes in total HAM-D17 and CGI scores measured over time through MMRM analysis. …”
Get full text

Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies by Falastin Salami, Lampros Spiliopoulos, Marlena Maziarz, Markus Lundgren, Charlotte Brundin, Rasmus Bennet, Magnus Hillman, Carina Törn, Helena Elding Larsson

“…Cross-sectional analyses were performed comparing lymphocyte and T-cell subpopulations between GAD-alum and placebo-treated subjects. Results. GAD-alum-treated children had lower levels of lymphocytes (109 cells/L) (p=0.006), T-cells (103 cells/μL) (p=0.008), T-helper cells (103 cells/μL) (p=0.014), and cytotoxic T-cells (103 cells/μL) (p=0.023) compared to the placebo-treated children 18 months from first GAD-alum injection. …”
Get full text

The effects of short-term creatine monohydrate supplementation on a single resistance exercise induced-indirect indicators some of cellular damage in male wrestler by رامین امیر ساسان, علی ضرغامی, مقصود نبیل پور

“…Moreover, the totalserum CK and LDH in both groups (supplement & placebo) were significantly increased 24 hour after theresistance exercise (P<0.05). …”
Get full text

The Effects of Neuroinflammation Induced by Typhoid Vaccine on Resting and Task‐Based Electroencephalography by Julia R Plank, Joseph CC Chen, Frederick Sundram, Nicholas Hoeh, Suresh Muthukumaraswamy, Joanne C Lin

“…EEG was recorded before and after placebo/vaccine administration during resting‐state and during performance of the Attention Network Test (ANT). …”
Get full text

Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings by Rushika Conroy, Gerardo Febres, Donald J. McMahon, Michael O. Thorner, Bruce D. Gaylinn, Irene Conwell, Louis Aronne, Judith Korner

“…Weight stable women after RYGB were randomized to receive placebo or recombinant human metreleptin (0.05 mg/kg twice daily). …”
Get full text

Efficacy and Safety of Antiepileptic Drugs in the Management of Behavioral Issues in Autism Spectrum Disorders: A Systematic Review and Meta-analysis by Sowmyashree Mayur Kaku, Ananya Varshney, Dhwani Ravi, Ann Maria Moncy

“…Meta-analysis of the remaining five RCTs showed no significant difference in the reduction of aggression and irritability between AEDs and placebo, with high heterogeneity (I2 = 93%). Sensitivity analysis confirmed the nonsignificance and high heterogeneity (I2 = 87%). …”
Get full text

Sipuleucel-T and Androgen Receptor-Directed Therapy for Castration-Resistant Prostate Cancer: A Meta-Analysis by Renliang Yi, Baoxin Chen, Peng Duan, Chanjiao Zheng, Huanyu Shen, Qun Liu, Chen Yuan, Weilin Ou, Zhiheng Zhou

“…Seven studies were included in the meta-analysis, with three studies in sipuleucel-T (totally 737 patients, 488 patients in treatment group, and 249 patients in placebo group) and four in AR-directed therapies (totally 5,199 patients, 3,015 patients in treatment group, and 2,184 patients in placebo group). …”
Get full text

Effect of nutrient support on structural and functional parameters of facial skin by Eugenia V. Shikch, Olga V. Zhukova, Maria S. Konstantinova, Anastasiia S. Koliadko

“…The dietary supplement and placebo were taken according to the following scheme: during the first 4 weeks of the study patients received placebo, then the subjects took VITABEAUTY® Hyaluronic Acid + Resveratrol for the next 6 weeks. …”
Get full text

A Randomized Controlled Clinical Trial of Lifestyle Intervention and Pioglitazone for Normalization of Glucose Status in Chinese with Prediabetes by Yingying Luo, Hongyuan Wang, Xianghai Zhou, Cuiqing Chang, Wei Chen, Xiaohui Guo, Jinkui Yang, Linong Ji, Sanjoy K. Paul

“…In this three-year follow-up study, overall, 60.0%, 50.3%, 56.6% and 65.1% reverted back to normoglycemic state over 3 years of follow-up in the conventional lifestyle intervention plus placebo, intensive lifestyle intervention plus placebo, conventional lifestyle intervention plus pioglitazone, and intensive lifestyle intervention plus pioglitazone groups, respectively. …”
Get full text

Feasibility and Safety of Perilla Seed Oil as an Additional Antioxidative Therapy in Patients with Mild to Moderate Dementia by Chuntida Kamalashiran, Junya Pattaraarchachai, Sombat Muengtaweepongsa

“…Three patients in the placebo group prematurely discontinued the medication, while only one patient in the treatment group quit the medication early. …”
Get full text

Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Transcranial Infrared Laser Stimulation by Douglas W. Barrett, Christopher G. Beevers, F. Gonzalez-Lima

“…Conclusions: While Deprexis alone significantly reduced depression scores in the placebo control group, this beneficial effect was augmented with the addition of TILS as an adjunct therapy. …”
Get full text