Impact of dapagliflozin on metabolic phenotype, hormone levels, and fertility in female mice after prolonged high-fat diet by Xiaolin Chen, Zhuoni Xiao, Na Dai, Mingxia Fan

“…Throughout the experiment period, dapagliflozin exhibited favorable effects on reproductive function along with insulin sensitivity and luteinizing hormone (LH) release from the pituitary gland.DiscussionIn conclusion, this study demonstrates that dapagliflozin alleviated HFD-induced reproductive dysfunction independently of obesity, peripheral tissue insulin resistance, and systemic inflammation, suggesting its potential as a promising treatment for diet-related ovulation disorders.…”
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PBVit: A Patch-Based Vision Transformer for Enhanced Brain Tumor Detection by Pratikkumar Chauhan, Munindra Lunagaria, Deepak Kumar Verma, Krunal Vaghela, Ghanshyam G. Tejani, Sunil Kumar Sharma, Ahmad Raza Khan

“…Brain Tumor holds a significant holds in human health, classified into three primary types: glioma, meningioma, and pituitary tumors. Early detection and accurate classification are vital for effective diagnosis and lowering healthcare costs. …”
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Comparing the Rates of Further Resection After Intraoperative MRI Visualisation of Residual Tumour Between Brain Tumour Subtypes: A 17-Year Single-Centre Experience by Daniel Madani, R. Dineth Fonseka, Sihyong Jake Kim, Patrick Tang, Krishna Muralidharan, Nicholas Chang, Johnny Wong

“…RESULTS: A total of 574 cases were identified, including 152 low-grade gliomas (LGG), 108 high-grade gliomas (HGG), 194 pituitary neuroendocrine tumours (PitNETs), 15 metastases, and 6 meningiomas. …”
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Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients by Jingwen Gan, Jie Chen, Rui-lin Ma, Yan Deng, Xue-song Ding, Shi-yang Zhu, Ai-jun Sun

“…The COM group may act on the hypothalamic-pituitary-gonadal axis (HPO) and its bypass, regulate multiple metabolism pathways such as phospholipids, amino acids, fatty acids, carnitine, bile acids, and glucose directly or indirectly in obese PCOS patients.…”
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Inflammatory Pain and Corticosterone Response in Infant Rats: Effect of 5-HT1A Agonist Buspirone Prior to Gestational Stress by Irina P. Butkevich, Viktor A. Mikhailenko, Tat'yana R. Bagaeva, Elena A. Vershinina, Anna Maria Aloisi, Vladimir A. Otellin

“…The serotonergic system and hypothalamo-pituitary-adrenal (HPA) axis are closely interrelated. …”
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A study looking at how missed somatropin injections affect growth in children with growth hormone deficiency: a plain language summary of publication by Jane Loftus, Bradley S. Miller, Craig S. Parzynski, Jose Alvir, Yong Chen, Priti Jhingran, Anu Gupta, Mitch DeKoven, Victoria Divino, Jenny Tse, Jing He, Michael Wajnrajch

“…Growth hormone - a protein made in the pituitary gland that helps the body grow properly. …”
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The neuroendocrine stress-response in insects: the history of the development of the concept by M. A. Eremina, N. E. Gruntenko

“…The lack of a hypothalamic-pituitary-adrenocortical system in insects was considered a proof of their inability to develop a stress reaction of the warm-blooded animals’ type. …”
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A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by Estrogen/Gestagen Therapy by Yoshihide Inayama, Koji Yamanoi, Baku Nakakita, Shimpei Shitanaka, Jumpei Ogura, Tsutomu Ohara, Mie Sakai, Haruka Suzuki, Koji Yasumoto, Ichiro Kishimoto, Yusuke Sagae, Yoshimi Kitawaki, Koh Suginami

“…Two years later, her pituitary hormonal status was evaluated in detail. …”
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Metabolic profile of blood serum in experimental arterial hypertension by A. A. Seryapina, A. A. Malyavko, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, A. L. Markel

“…The etiology of essential hypertension is intricate, since it employs simultaneously various body systems related to the regulation of blood pressure in one way or another: the sympathetic nervous system, renin-angiotensin-aldosterone and hypothalamic-pituitary-adrenal systems, renal and endothelial mechanisms. …”
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The Impact of Physical Activities on Male Fertility: A Systematic Review by Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Julia Białeta, Karolina Siembab, Katarzyna Rowińska, Michalina Jurkiewicz, Wiktor Garbarczyk, Wiktoria Pysiewicz, Agnieszka Napieralska

“…Another issue discussed is the negative impact of exercise on fertility, as well as injuries in the perineal region—some of which directly affect organs, surrounding tissues (such as nerves), and regulatory mechanisms like hypothalamic-pituitary-gonadal axis. Materials and Methods This study was conducted as a comprehensive literature review based on scientific articles and research papers accessed through two primary databases: PubMed and Google Scholar. …”
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Conceptualising Centres of Clinical Excellence: A Scoping Review by Elizabeth A Lynch, Jeroen M Hendriks, Natalie Ann Fini, Thoshenthri Kandasamy, Rachel C Stockley, Lemma N Bulto

“…All but one initiative focused on one clinical condition/population, most commonly cardiovascular disease (n=8, 17%), spinal surgeries (n=4, 9%) and pituitary tumours (n=4, 9%). Most initiatives (n=30, 67%) described a structured process to establish CoCE. …”
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Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes by Ye Zhang, Yanpeng Xing, Haibo Yuan, Xiaokun Gang, Weiying Guo, Zhuo Li, Guixia Wang

“…The impairment of hypothalamic-pituitary-adrenal axis activity may be one of the underlying mechanisms of the glycometabolic dysfunctions in OSA with T2DM patients.…”
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Severe reversible cardiomyopathy associated with adrenal crisis caused by isolated adrenocorticotropin deficiency: a case report by Li Wang, Fangfang Bu, Lanjie He, Guihua Yao, Guihua Yao

“…Isolated adrenocorticotropin deficiency (IAD) is a rare condition of pituitary adrenal insufficiency. In this case report, we describe a 74-year-old male patient who was in good physical health and was admitted to our hospital with a sudden onset of fever and confusion that was complicated by hyponatremia and hypotension. …”
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Epigenetics of suicidal behavior by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, S. B. Malykh, V. V. Viktorov, E. K. Khusnutdinova

“…Published data identified multiple genes including those involved in the functioning of serotonergic (SLC6A4, TPH, 5-HT1A), hypothalamic-pituitary-adrenal systems (FKBP5) and polyamines (SAT and OATL1) associated with suicidal behavior. …”
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Spawning biology, breeding, and larval rearing techniques for Xenentodon cancila (Hamilton) for aquaculture and recreational use in Bangladesh: The first approach by Paul Shyamal Kumar, Sarker Bhakta Supratim, Sultana Nahid, Pall Jewel Chandra, Perven Tania, Saha Debasish, Majumdar Priyanka Rani

“…Nine doses of common carp pituitary gland (CPG), human chorionic gonadotropin (HCG), and Ovaprim for breeding were administered, except in the control treatment that was without hormones. …”
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<i>Lin28b-let-7</i> Modulates mRNA Expression of <i>GnRH1</i> Through Multiple Signaling Pathways Related to Glycolysis in GT1-7 Cells by Yujing Xie, Xin Li, Meng Wang, Mingxing Chu, Guiling Cao

“…In this study, the mRNA expression levels of <i>Lin28b</i> and <i>let-7</i> in the pubertal and juvenile goat hypothalamus and pituitary gland were detected, and <i>Lin28b</i> expression in the pubertal hypothalamus decreased significantly compared with that in juvenile tissues. …”
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GH, IGF-1, and Age Are Important Contributors to Thyroid Abnormalities in Patients with Acromegaly by Xia Wu, Lu Gao, Xiaopeng Guo, Qiang Wang, Zihao Wang, Wei Lian, Wei Liu, Jian Sun, Bing Xing

“…The demographic and clinical information were recorded. Specimens of pituitary adenomas and thyroid cancer were collected for BRAF mutation assessments. …”
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Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome by Na Li, Chenghao Yang, Huiyu Xie, Yinghong Liu, Yuanpeng Liao

“…Aerobic exercise can alleviate the internal inflammation by relieving leptin resistance and may mitigate the sex hormone disorder and hyperandrogenism in rats with PCOS by affecting the hypothalamic-pituitary-ovarian axis.…”
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Transcriptome and DNA methylation analysis of the goat pineal gland during puberty by Bochao Zhang, Genbao Zhu, Jianling Wu, Huihui Xie, Jiankun Cui, Wei Qian, Qing Yi, Fuqiang Pan, Fugui Fang, Yinghui Ling, Yunhai Zhang, Yunsheng Li, Ya Liu

“…Abstract Previous studies have confirmed that methylation regulates gene transcription in the hypothalamus-pituitary-gonadal axis during puberty initiation, but little is known about the regulation of DNA methylation on gene expression in the pineal gland. …”
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Gaps in the management of adrenal insufficiency in melanoma survivors: a retrospective cohort studyResearch in context by Wei Lin, Wei Wang, F. Stephen Hodi, Le Min

“…Methods: This retrospective cohort study analyzed melanoma patients treated with immune checkpoint inhibitors (ICIs) with SAI (Mel_SAI, n = 161), without SAI (Mel_CON, n = 168), and patients with pituitary adenoma-related SAI (Pit_SAI, n = 106) at our institution from January 2013 to November 2023. …”
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