Engineering a live-attenuated porcine reproductive and respiratory syndrome virus vaccine to prevent RNA recombination by rewiring transcriptional regulatory sequences by Liwei Li, Jinxia Chen, Zhengda Cao, Ziqiang Guo, Jiachen Liu, Yanjun Zhou, Guangzhi Tong, Fei Gao

“…However, owing to the wide variety of live vaccines, non-standard use, and the wild viruses prevalent on pig farms, new strains, generated via RNA recombination, are continuously emerging. …”
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Systematic identification of secondary bile acid production genes in global microbiome by Yuwei Yang, Wenxing Gao, Ruixin Zhu, Liwen Tao, Wanning Chen, Xinyue Zhu, Mengping Shen, Tingjun Xu, Tingting Zhao, Xiaobai Zhang, Lixin Zhu, Na Jiao

“…Additionally, we proposed the pig as a particularly suitable animal model for investigating secondary bile acid production in humans, given its closely aligned secondary bile acid production gene composition. …”
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Longitudinal serological and virological survey of hepatitis E virus in wild boar (Sus scrofa majori, Maremman wild boar) and fallow deer (Dama dama) populations in a protected are... by Luca De Sabato, Mariagiovanna Domanico, Paola De Santis, Daniele Cecca, Giulia Bonella, Giovanni Mastrandrea, Roberta Onorati, Luigi Sorbara, Bianca Maria Varcasia, Barbara Franzetti, Andrea Caprioli, Antonio Battisti, Fabio Ostanello, Ilaria Di Bartolo

“…Hepatitis E virus (HEV) is recognized as an emerging zoonosis. Pigs and wild boars are considered the main reservoirs of zoonotic HEV-3 and HEV-4 genotypes. …”
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Identification and Functional Analysis of miRNAs in Extracellular Vesicles of Semen Plasma from High- and Low-Fertility Boars by Weidong Chen, Yanshe Xie, Zhiqian Xu, Yijun Shang, Wenzheng Yang, Pengyao Wang, Zhenfang Wu, Gengyuan Cai, Linjun Hong

“…AI technology has been widely used in pig production in China, but boar fertility affects the effectiveness of AI, and more and more studies have shown that there are significant differences in the fertility of boars with similar semen quality indicators. …”
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<i>Limosilactobacillus reuteri</i> ZY15 Alleviates Intestinal Inflammation and Barrier Dysfunction via AKT/mTOR/HIF-1α/RORγt/IL-17 Signaling and the Gut Microbiota in ETEC K88-Chal... by Xin Xu, Hongwei Zhang, Kun Meng, Hongying Cai, Weiwei Liu, Liye Song, Zihan Zhang, Qijun Zhu, Xiling Han, Yunsheng Han, Peilong Yang

“…This study investigates the mechanisms by which <i>L. reuteri</i> ZY15, isolated from healthy pig feces, mitigates intestinal barrier damage and inflammation caused by oxidative stress in Enterotoxigenic <i>Escherichia coli</i> (ETEC) K88-challenged mice. …”
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Genomic characteristics of a Streptococcus suis of ST353 resulting in severe endophthalmitis with bilateral deafness by Liang Shen, Yanfei Tong, Shichao Li, Yuda Chen, Ruhan A, Zhen Li, Wenling Wang, Lijuan Yin, Jiuming Zou, Ziyong Sun, Changcheng Wu, Wenjie Tan, Haijuan Wang

“…Streptococcus suis (S. suis) can be transmitted to humans through exposure to pigs or consumption of raw pork and causes serious diseases. …”
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A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets by Chao Li, Jinhao Li, Bangjun Gong, Hu Xu, Zhenyang Guo, Lirun Xiang, Siyu Zhang, Qi Sun, Jing Zhao, Menglin Zhang, Yan-Dong Tang, Chaoliang Leng, Jianan Wu, Qian Wang, Jinmei Peng, Guohui Zhou, Huairan Liu, Tongqing An, Xuehui Cai, Zhi-Jun Tian, Hongliang Zhang

“…Multiple porcine reproductive and respiratory syndrome virus (PRRSV) subtypes coinfect numerous pig farms in China, and commercial PRRSV vaccines offer limited cross-protection against heterologous strains. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…“What Does the First Successful Test of a Pig-to-Human Kidney Transplant Mean?,” ScienceNews, October 22, 2021, https://www.sciencenews.org/article/xenotransplantation-pig-human-kidney-transplant.; Koplon, S. …”
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Preparation and application of porcine broadly neutralizing monoclonal antibodies in an immunoassay for efficiently detecting neutralizing antibodies against foot-and-mouth disease... by Yimei Cao, Fengjuan Li, Xiangchuan Xing, Huiyan Zhang, QiongQiong Zhao, Pu Sun, Yuanfang Fu, Pinghua Li, Xueqing Ma, Jing Zhang, Zhixun Zhao, Hong yuan, Jian Wang, Tao Wang, Huifang Bao, Xingwen Bai, Dong Li, Qiang Zhang, Kun Li, Zengjun Lu

“…In this study, a porcine broadly neutralizing monoclonal antibody (PO18-10) against FMDV was obtained from the heterologous sequentially vaccinated pig using single-B-cell antibody technology. A competitive enzyme-linked immunosorbent assay (C-ELISA) for detecting neutralizing antibodies against FMDV serotype O was developed using biotinylated PO18-10 as a detector antibody. …”
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Classical swine fever: a retrospective analysis of the epizootic situation in the Russian Federation (2007–2021) and forecast for 2022 by A. S. Oganesyan, A. A. Shevtsov, A. V. Shcherbakov, F. I. Korennoy, A. K. Karaulov

“…Expansion of vaccination coverage since 2011 is one of the factors contributing to a decrease in the number of clinical CSF cases registered in domestic pigs of the Russian Federation. The infection spread in domestic pigs is still on a downward trend. …”
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Bovine milk consumption affects the transcriptome of porcine adipose stem cells: Do exosomes play any role? by Katherine Swanson, Jimmy Bell, David Hendrix, Duo Jiang, Michelle Kutzler, Brandon Batty, Melanie Hanlon, Massimo Bionaz

“…C pigs. Bioinformatic analysis of DEG indicated an inhibition of the immune, neuronal, and endocrine systems and insulin-related pathways in ASC of milk-fed pigs compared with maltodextrin-fed pigs. …”
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Beneficial haemodynamic effect of indomethacin during endotoxin shock in anaesthetized pigsputative involvement of nitric oxide? by T. Mózes, E. M. van Gelderen, E. J. Mylecharane, P. R. Saxena

“…Endotoxin shock was induced in 31 anaesthetized pigs by infusion of 5 μg/kg of Escbeicbia coli endotoxin (LPS) over 60 min into the superior mesenteric artery. …”
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Alveolar Overdistension as a Cause of Lung Injury: Differences among Three Animal Species by Manuel García-Delgado, Inés Navarrete-Sánchez, Virginia Chamorro-Marín, Juan Carlos Díaz-Monrové, Javier Esquivias, Enrique Fernández-Mondéjar

“…Although some histological lesions are observed in pigs and rats, the lesions do not appear to be relevant.…”
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Role of endogenous nitric oxide on PAF-induced vascular and respiratory effects by M. Clement, M. Albertini

“…PAF was also administered to three of these pigs after indomethacin infusion (3 mg/kg, i.v.). …”
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Toxin and capsule production by Bacillus cereus biovar anthracis influence pathogenicity in macrophages and animal models. by Treenate Jiranantasak, Andrew P Bluhm, Donald J Chabot, Arthur Friedlander, Richard Bowen, Ian A McMillan, Ted L Hadfield, Airn Hartwig, Jason K Blackburn, Michael H Norris

“…Sterne vaccinated guinea pigs had significantly increased anti-PA titers compared to the unvaccinated control group. …”
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Serological Evidence and Coexposure of Selected Infections among Livestock Slaughtered at Eastern Cape Abattoirs in South Africa by K. D. Mazwi, F. B. Kolo, I. F. Jaja, R. P. Bokaba, Y. B. Ngoshe, A. Hassim, L. Neves, H. van Heerden

“…A total of 565 animals comprising of 280 cattle, 200 sheep, and 85 pigs were screened using RBT, iELISA, CFT, and AMOS-PCR. …”
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DIFFERENCES IN OSTEOBLAST COUNT AND ITS EFFECT ON ORTHODONTIC MOVEMENT OF DIABETIC MODELS’ TEETH AFTER ORAL ADMINISTRATION OF OLIVE OIL by Salwa Az-Zahra, Ryana Budi Purnama, Fani Tuti Handayani, Setiadi W. Logamarta

“…Method: 25 male guinea pigs divided into four groups: diabetic guinea pigs treated with olive oil at a dose of 0.7; 1.05; 1.4 ml/day, distilled water, and healthy guinea pigs were given aquadest. …”
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Response to Novelty Correlates with Learning Rate in a Go/No-Go Task in Göttingen Minipigs by Nanna Marie Lind, Anette Moustgaard

“…In conclusion, in addition to ‘cognitive’ ability, ‘temperamental’ factors are likely to influence learning in individual pigs.…”
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Specific features of African swine fever control activities in China by M. D. Lozovoy, S. V. Shcherbinin, A. K. Karaulov

“…African swine fever is a highly contagious viral disease of pigs; however, no vaccines are available to control it. …”
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Improving long-term postoperative survival in a porcine cardiac valve surgery model utilizing cardiopulmonary bypass via left thoracotomy: a single-center experience sharing insigh... by Qingping Xia, Yong Cao, Jialuan Li, Jie Jiang, Xuan Lu, Li Deng

“…Automatic heart resumption occurred in 63.8% of pigs, while the remainder required electrical defibrillation or cardiac massage. …”
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