Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course by Elisabetta Zucchi, Elisabetta Zucchi, Federico Banchelli, Cecilia Simonini, Sara De Biasi, Ilaria Martinelli, Giulia Gianferrari, Giulia Gianferrari, Domenico Lo Tartaro, Andrea Cossarizza, Andrea Cossarizza, Roberto D’Amico, Roberto D’Amico, Jessica Mandrioli, Jessica Mandrioli

“…However the observed changes in Treg phenotypes, such as the decrease in PD1+Tregs, indicate that phenotypic variations may warrant further investigation for their potential role in ALS progression and therapeutic targeting.…”
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DEL phenotype in RhD-negative North Indian blood donors by Paramjit Kaur, Ravneet K. Bedi, Tanvi Sood, Kshitija Mittal, Gagandeep Kaur

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Genomic and phenotypic stability of fusion-driven pediatric sarcoma cell lines by Merve Kasan, Florian H. Geyer, Jana Siebenlist, Martin Sill, Rupert Öllinger, Tobias Faehling, Enrique de Álava, Didier Surdez, Uta Dirksen, Ina Oehme, Katia Scotlandi, Olivier Delattre, Martina Müller-Nurasyid, Roland Rad, Konstantin Strauch, Thomas G. P. Grünewald, Florencia Cidre-Aranaz

“…Recent reports showed that highly mutated adult carcinoma cell lines (mainly HeLa and MCF-7) present striking diversity across laboratories and that long-term continuous culturing results in genomic/transcriptomic heterogeneity with strong phenotypical implications. Here, we hypothesize that oligomutated pediatric sarcoma cell lines mainly driven by a fusion transcription factor, such as Ewing sarcoma (EwS), are genetically and phenotypically more stable than the previously investigated adult carcinoma cell lines. …”
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Differences of active substances in different fruit phenotypes of Lycium ruthenicum Murr. by SHI Cui, KONG Dongsheng, WU Yao, BAO Jingwei

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Obesity Phenotypes, Lifestyle Medicine, and Population Health: Precision Needed Everywhere! by Jean-Pierre Després, Dominic J. Chartrand, Adrien Murphy-Després, Isabelle Lemieux, Natalie Alméras

“…The heterogeneity of obesity phenotypes represents a clinical challenge to the evaluation of cardiometabolic risk associated with a given body mass index (BMI). …”
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MAP: Mutation Arranger for Defining Phenotype-Related Single-Nucleotide Variant by In-Pyo Baek, Yong-Bok Jeong, Seung-Hyun Jung, Yeun-Jun Chung

“…In this study, in order to support defining the recurrent mutations or phenotype-specific mutations from NGS data of a group of cancers with diverse phenotypes, we aimed to develop a user-friendly tool, named mutation arranger for defining phenotype-related SNV (MAP). …”
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Correction of the TNF-LTα-Deficient Phenotype by Bone Marrow Transplantation by Bernhard Ryffel, Michel Le Hir, Mathias Müller, Hans-Pietro Eugster

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Phenotypic and genetic variability of a tetraploid wheat collection grown in Kazakhstan by A. Zatybekov, S. Anuarbek, S. Abugalieva, Y. Turuspekov

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Clinical phenotypes and associated factors in knee osteoarthritis in an African black population by Charles Sougué, Malick Diallo, Yannick Laurent Tchenadoyo Bayala, Ismaël Ayouba Tinni, Fulgence Kaboré, Wendlassida Joelle Stéphanie Zabsonré Tiendrebeogo, Patrick Wendpouiré Hamed Dakouré, Dieu-Donné Ouedraogo

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Phenotypic Detection of Metallo-β-Lactamase in Imipenem-Resistant Pseudomonas aeruginosa by Yalda Khosravi, Mun Fai Loke, Eng Guan Chua, Sun Tee Tay, Jamuna Vadivelu

“…Therefore, the IP/IPI E-test is a viable alternative phenotypic assay to detect MBL production in IRPA in our population in circumstances where PCR detection is not a feasible option.…”
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Role of Epigenetics in Modulating Phenotypic Plasticity against Abiotic Stresses in Plants by Fayaz Ahmad Dar, Naveed Ul Mushtaq, Seerat Saleem, Reiaz Ul Rehman, Tanvir Ul Hassan Dar, Khalid Rehman Hakeem

“…Besides, it has been observed that environmental stresses cause specific changes in the epigenome that are closely associated with phenotypic modifications. However, the relationship between epigenetic modifications and phenotypic plasticity is still debatable. …”
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Cochleovestibular Phenotype in a Rare Genetic MED13L Mutation by Mariam Shahid, Mohamed Ahmed, Shivaram Avula, Soumit Dasgupta

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A patient with probable rare blood Group B(A) phenotype by Avineesh Chandra, P. M. Bala Bhasker, Romesh Jain, Rakesh Kumar, Subodh Srivastava

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Phenotypic Resistance of (MRSA) Clinical Isolates to Some Macrolide Antibiotic Groups by Ali Yaseen, Jaleel Samanje, Qahtan Adnan Rasheed, Rafah Sabah Barrak, Afraa Brahim

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High-Throughput Phenotyping for Agronomic Traits in Cassava Using Aerial Imaging by José Henrique Bernardino Nascimento, Diego Fernando Marmolejo Cortes, Luciano Rogerio Braatz de Andrade, Rodrigo Bezerra de Araújo Gallis, Ricardo Luis Barbosa, Eder Jorge de Oliveira

“…Large-scale phenotyping using unmanned aerial vehicles (UAVs) has been considered an important tool for plant selection. …”
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Phenotypic effects of different doses of physical and chemical mutagens in cotton plants by H.M Winkler, A.E. Cereijo, G.J. Scarpin, P.N. Dileo, R.J. Muchut, R.A. Roeschlin, F.G. Lorenzini, M.J. Paytas, Alejandra M. Landau

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Applications and Challenges of High-Throughput Phenotyping of Crops at Ground and Aviation Scales by Longyue CHEN, Dandan DUAN, Weibing XU, Zuolin LI, Chong ZHAO, Yi JIANG, Yonggang GAO, Wenqing ZUO

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Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases by Zhiping Wei, Jintao Yuan, Gaoying Wang, Dickson Kofi Wiredu Ocansey, Zhiwei Xu, Fei Mao

“…This review summarizes the role of MSCs in relieving autoimmune diseases via the regulation of T cell phenotypes.…”
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Novel Phenotype in Unbalanced 7;9 Translocation with Critical Incidental Finding by Julie Fischer, Luis Rohena

“…This case expands on the phenotype of this patient’s unbalanced 7;9 translocation as well as highlights the importance of secondary findings in genetic testing.…”
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Bisphosphonate Treatment in a Patient Affected by MPS IVA with Osteoporotic Phenotype by Albina Tummolo, Orazio Gabrielli, Alberto Gaeta, Maristella Masciopinto, Lucia Zampini, Luigi Michele Pavone, Paola Di Natale, Francesco Papadia

“…We suggest that the use of bisphosphonates may be an interesting supportive therapeutic option for Morquio A patients with osteoporotic phenotype, but further studies involving more patients are necessary to confirm our findings.…”
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