Genome-Wide Association Study of Metabolic Syndrome in Koreans by Seok Won Jeong, Myungguen Chung, Soo-Jung Park, Seong Beom Cho, Kyung-Won Hong

“…To reconsider the discarded true-positive loci, we attempted to include the functional variants (nonsynonymous SNPs [nsSNPs] and expression quantitative trait loci [eQTL]) among the top 5,000 SNPs based on the proportion of phenotypic variance explained by genotypic variance. …”
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Physical activities and breast cancer: a Mendelian randomization study by Lishan Ding, Qingliang Chen, Hao Liang, Meng Shen, Ming Zheng, Zhaojun Li

“…Material and methods Genome-wide association studies utilizing data from the UK Biobank baseline were employed to analyze PA phenotypes, encompassing 460,376 participants. Summary data for BC, comprising 122,977 cases and 105,974 controls, were obtained from the BC Association Consortium. …”
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Biodegradation of rice husks for glucose production using Streptomyces coelicolor STRP-19 by Waleed M. Abdulkhair, Younes M. Rashad, Mohamed Hafez, Ahmed M. Abd-ElGawad, Mohamed Bourouah

“…Although several Streptomyces isolates showed rice husks-degrading activity, STRP-19 isolate was the most potent and was identified as S. coelicolor using phenotypic and genetic methods based on 16S rRNA gene sequencing. …”
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Genome-wide discovery of InDels and validation of PCR-Based InDel markers for earliness in a RIL population and genotypes of lentil (Lens culinaris Medik.). by K M Shivaprasad, Muraleedhar Aski, Gyan Prakash Mishra, Subodh Kumar Sinha, Soma Gupta, Dwijesh C Mishra, Amit Kumar Singh, Akanksha Singh, Kuldeep Tripathi, Ranjeet Ranjan Kumar, Atul Kumar, Shiv Kumar, Harsh K Dikshit

“…An InDel marker I-SP-356.6 (chr. 3; position 356,687,623; positioned 174.5 Kb from the LcFRI gene) was identified as having a phenotypic variance explained (PVE) value of 47.7% for earliness when validated in a RIL population. …”
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Clinical features, pathological characteristics, and prognosis of patients with IgA nephropathy complicated with nephrotic syndrome by Li Tan, Lu-Hua Jin, Yi-Qin Wang, Wei Chen, Qiong Wen

“…In conclusions, significant differences in clinicopathological features and long-term prognosis were observed among NS-IgAN patients with varying pathological phenotypes.…”
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A population genomics approach to unlock the genetic potential of lablab (Lablab purpureus (L.) Sweet), an underutilized tropical forage crop by A. Teshome, E. Habte, J. Cheema, A. Mekasha, H. Lire, M. S. Muktar, J. Quiroz-Chavez, C. Domoney, C. S. Jones

“…Here, we resequenced one hundred and forty-two lablab accessions, utilised whole genome genotyping approaches, and conducted multi-locational phenotyping over two years. Results The selected lablab accessions displayed significant agro-morphological variation in eight analysed traits, including plant height, total fresh weight, and total dry weight. …”
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Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys by Ayaka Domon, Kentaro Katayama, Yuki Tochigi, Hiroetsu Suzuki

“…There was a marked difference in the etiology of DEK by gender: DM phenotypes including polyuria, polydipsia, and hyperglycemia (nonfasting blood glucose over 300 mg/dl) were found in male rats aged over 10 weeks but not in female rats. …”
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A genome-wide association study identified SNP markers and candidate genes associated with morphometric fruit quality traits in mangoes by Shamseldeen Eltaher, Jin Li, Barbie Freeman, Sukhwinder Singh, Gul Shad Ali

“…Conclusions To choose the most promising mango accessions for future breeding and for closing genetic gaps among the accessions and increasing genetic diversity, a new selection method is suggested based on phenotypic traits such as high-yielding mango fruit cultivars, number of reference alleles, and genetic distance among the selected genotypes. …”
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Alendronate partially rescues the periodontal defects in OIM mouse model of osteogenesis imperfecta by Po-Jung Chen, Ke Wang, Meng-Hsuan Lin, Radhika Sharma, Zana Kalajzic, Mara O’Brien, Sumit Yadav

“…With alendronate treatment, however, we could partially rescue these phenotypes. This study, for the first time, characterized periodontal defects in oim mice, detailed craniofacial defects and demonstrated the effectiveness of alendronate in partially restoring these defects.…”
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Case report of neurobrucellosis: a rare complication and neuroimaging findings of a common disease by Yu Zhang, Yu Zhang, Xiao-Yi Zou, Xiao-Yi Zou, Ling Liu

“…Data on demographics, clinical phenotypes and symptoms, cerebrospinal fluid investigations, radiological investigations, and therapies were collected and reviewed. …”
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Effect of epigallocatechin-3-gallate (EGCG) on cognitive functioning and the expression of APP and BDNF in the hippocampus of rats with streptozotocin -induced Alzheimer-like disea... by Farnaz Ghayour Babaei, Ehsan Saburi, Fatemeh Forouzanfar, Mohadese Asgari, Zakieh Keshavarzi, Vahid Hajali

“…We aimed to investigate the potential therapeutic effects of the active substance of green tea, epigallocatechin-3-gallate (EGCG), on behavioral phenotypes and markers of neurogenesis in an Alzheimer disease (AD) rat model. …”
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Drosophila melanogaster inhabiting northern regions of European Russia are infected with Wolbachia which adversely affects their life span by N. V. Roshina, A. V. Symonenko, A. V. Krementsova, Е. A. Tsybul’ko, V. E. Alatortsev, E. G. Pasyukova, D. V. Mukha

“…In D. melanogaster, Wolbachia affects various life history traits, behaviour, sensitivity to stress and viral infection. The phenotypic effects of Wolbachia might evolve to promote its further spreading, increasing the interest in exploring the spread of Wolbachia, in particular, at the boundar­ies of the D. melanogaster habitat, in association with the effects on vital traits of host species. …”
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Response of the gut microbiome and metabolome to dietary fiber in healthy dogs by Amrisha Bhosle, Matthew I. Jackson, Aaron M. Walsh, Eric A. Franzosa, Dayakar V. Badri, Curtis Huttenhower

“…Thus, our study corroborates findings in human cohorts and reinforces the role of personalized microbiomes even in seemingly phenotypically homogeneous subjects.IMPORTANCEConsumption of dietary fiber changes the composition of the gut microbiome and, to a larger extent, the associated metabolites. …”
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Candidate genes for domestication and resistance to cold climate according to whole genome sequencing data of Russian cattle and sheep breeds by N. S. Yudin, D. M. Larkin

“…It is known that different species of animals, when living in the same environmental conditions, can form similar phenotypes. The study of the convergent evolution of several species under the influence of the same environmental factor makes it possible to identify common mechanisms of genetic adaptation. …”
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Changes of Cell Adhesion Molecules and T Cell Subset Populations in Acute Myeloid Leukemia Patients Undergoing Intravenous Administration of Cytarabine Supplemented with Idarubicin by Jinhua Piao, Didi Wang, Siying Pei, Tangdong Ge, Jing Li, Pengxia Zhang

“…Soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), IL-10, and IL-35 were measured by ELISA methods. Phenotypic characteristics of T cell subsets including CD4+, CD8+, CD4+IL-10 Tregs, and CD4+CD25+CD127−Foxp3+ Tregs were analyzed by flow cytometry. …”
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Hotspots and research trends of gut microbiome in polycystic ovary syndrome: a bibliometric analysis (2012–2023) by Ruishan Wu, Zhensheng Mai, Xiaoyan Song, Wenzhong Zhao

“…Additionally, “gut dysbiosis,” “phenotypes,” “adolescents,” “metabolomics,” “metabolites,” “fecal microbiota transplantation,” and “IL-22” have emerged as the primary keywords reflecting recent research trends.ConclusionThis bibliometric analysis explores how the gut microbiome influences endocrine and metabolic disorders related to PCOS, emphasizing its role in the development of PCOS and treatments targeting the gut microbiome. …”
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Phenetic analysis of natural apricot populations in the Mountainous Dagestan for endocarp (stone) features by D. M. Anatov

“…Studying the intraspecies diversity of fruit crop wild relatives is one of the leading trends in botanical and genetic resource research associated with identification and utilization of the phenotypic potential of the population and species, the initial stage in plant breeding and introduction processes, and a prerequisite to solving a number of problems posed by the theory of microevolution, biosystematics and population biology. …”
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Construction and characterization of an infectious cDNA clone of turtle grass virus X from a naturally infected Thalassia testudinum plant by Luis Alvarado-Marchena, Bradley T. Furman, Mya Breitbart

“…Agroinfection assays of potexvirus-free T. testudinum plants resulted in systemic infections by TGVX, as confirmed by multiplex RT-PCR experiments and phenotypic changes reflecting virus-induced symptoms. …”
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Molecular Epidemiology and Antimicrobial Resistance of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae in Retail Cattle Meat by Nasrin Akter Liza, Hemayet Hossain, Md. Shahidur Rahman Chowdhury, Jarin Al Naser, Rayhan Mahmud Lasker, Asikur Rahman, Md. Ariful Haque, Md. Al Mamun, Md. Mukter Hossain, Md. Mahfujur Rahman

“…Antimicrobial resistance was observed against 12 antibiotics. According to the phenotypic resistance pattern determined through the disk diffusion method, all isolates (100%) were resistant to ampicillin, amoxicillin, cefuroxime, cefotaxime, and colistin. …”
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Faecalibacterium prausnitzii regulates carbohydrate metabolic functions of the gut microbiome in C57BL/6 mice by Peiling Geng, Ni Zhao, Yufan Zhou, Reuben S. Harris, Yong Ge

“…Collectively, our results reveal a crucial role of UT1 in facilitating the carbohydrate metabolism of the gut microbiome and expand our understanding of the genetic and phenotypic diversity of F. prausnitzii.…”
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