Methodical approaches in experimental modelling of non-alcoholic fatty liver disease by N. V. Bivalkevich, Yu. K. Denisenko, T. P. Novgorodtseva

“…Today‘s methods of NAFLD modelling can be divided into two extensive groups: induction of liver disease by genetic mutation, and phenotypic development of NAFLD due to alimentary factor. …”
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Forecasting Range Shifts in Terrestrial Alpine Insects Under Global Warming by Fabio Leonardo Meza‐Joya, Mary Morgan‐Richards, Steven A. Trewick

“…Alpine insects exhibit some potential to respond to rising temperatures via genetic change or phenotypic plasticity. Thus, future efforts should incorporate biological processes by using flexible hybrid niche modelling approaches to enhance the biological realism of predictions. …”
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Epidemiology of transthyretin (ATTR) amyloidosis: a systematic literature review by Diego Delgado, Firas Dabbous, Nitin Shivappa, Faizan Mazhar, Eric Wittbrodt, Divya Shridharmurthy, Krister Järbrink

“…Studies evaluating populations with genotypes and phenotypes of ATTR amyloidosis (variant and wild-type cardiomyopathy, polyneuropathy, and mixed) were included. …”
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Serum Matrix Metalloproteinases and Risk of Urologic Cancers: A Bidirectional Mendelian Randomization Study by BoWen Yang, XiaoYu Zeng, HanYu Wang, JiuHuan Feng, ShuFang Hou

“…However, the causal relationship between these two phenotypes remains uncertain. This study aims to examine the bidirectional causal relationship between serum MMPs and three urologic cancers: kidney, prostate, and bladder cancer. …”
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Generalized lymphatic anomaly in a pediatric patient manifesting as a rare presentation of hemorrhagic pleural effusion: a case report by Xuehong Zhang, Jiuling Wang, Shouxing Duan, Yongping Yan, Libin Wang

“…Conclusion In patients with generalized lymphatic anomalies (GLAs), involvement of the thoracic cavity may lead to hemorrhagic pleural effusion, thereby broadening the landscape of GLA phenotypic presentations. Furthermore, this case highlights the importance of complete radiological evaluation of susceptible patients with GLA to avoid diagnostic delay in this morbid condition. …”
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Multimodal Imaging Characteristics of ADRP in a Family with p.Thr58Arg Substituted RHO Mutation by Misty Ruppert, John Pyun, K. V. Chalam, David Sierpina

“…Additionally, we compare the patient’s phenotypic findings to those of her offspring, who was also affected by adRP. …”
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Adipose-Derived Stem Cells in Bone Tissue Engineering: Useful Tools with New Applications by Gabriele Storti, Maria Giovanna Scioli, Bong-Sung Kim, Augusto Orlandi, Valerio Cervelli

“…The use of ASCs has offered significative new advancements in the efficacy of each of these elements. Notably, the phenotypic study of ASCs allowed discovering cell subpopulations, which have enhanced osteogenic and vasculogenic capacity. …”
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Localization of the quantitative trait loci related to lodging resistance in spring bread wheat (<i>Triticum aestivum</i> L.) by I. N. Leonova, E. V. Ageeva

“…Here we present the results of localization of the genomic regions associated with resistance to lodging, plant height, and upper internode diameter in Russian bread wheat varieties. Phenotypic screening of 97 spring varieties and breeding lines was carried out in the field conditions of the West Siberian region during 2017–2019. …”
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Online resources on gene networks containing human and animal data by E. V. Ignatieva, D. A. Afonnikov, N. A.  Kolchanov

“…Gene networks are molecular genetic systems that ensure the formation of phenotypic characteristics of organisms (molecular, biochemical, structural, morphological, behavioral, etc.) based on  information encoded in their genomes. …”
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Idiopathic giant cell myocarditis or cardiac sarcoidosis? A retrospective audit of a nationwide case series by Kaj Ekström, Anne Räisänen‐Sokolowski, Jukka Lehtonen, Hanna‐Kaisa Nordenswan, Mikko I. Mäyränpää, Markku Kupari

“…The possibility that they represent different phenotypes of a single disease has been debated. Methods and results We made a retrospective audit of 73 cases of GCM diagnosed in Finland since the late 1980s. …”
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Premonitory urge in tic disorders – a scoping review by John B. Wohlgemuth, Kelly H. Watson, Kayce D. Gill, David A. Isaacs

“…They are highly prevalent, frequently bothersome, and increasingly recognized as a central phenotypic feature in tic disorder populations. This scoping review aimed to systematically consolidate published knowledge and identify knowledge gaps regarding premonitory urges in primary tic disorders.MethodsSearch strategies were deployed in five databases and five topic-relevant journals. …”
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Genetic parameters of production and reproduction traits of Mediterranean buffaloes under tropical conditions by Iván A. Cárdenas, Miguel A. Chacón

“…For this reason, the zootechnical performance of a herd of Mediterranean buffaloes in Puerto Concha, Zulia state, Ven-ezuela, was evaluated. The phenotypic behavior and genetic parameters of the characteristics of milk yield (MY), lactation length (LL), calving interval (CI), age at first calving (AFC), and peak lactation (PLAC) were analyzed. …”
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Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome by Kathryn Jespersen, Chenxin Li, Rishi Batra, Christopher A. Stephenson, Paul Harding, Kylie Sestak, Ryan T. Foley, Harrison Greene, Trevor Meisinger, Jason R. Cook, B. Timothy Baxter, Wanfen Xiong

“…This might be mediated by inducing a contractile phenotypic change of SMC. Our results suggest that inhibiting Notch3 activation may provide a strategy to prevent and treat aortic aneurysms in MFS.…”
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Maintien du potentiel adaptatif chez les plantes domestiquées à propagation clonale by Doyle McKey, Marianne Elias, Benoît Pujol, Anne Duputié, Marc Delêtre, Delphine Renard

“…Cloning is the only efficient way to “capture” and multiply initially rare favourable phenotypes in habitually outcrossed plants such as manioc. …”
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An Extremely Rare SRD5A2 Gene c.485A>C Mutation in a Compound Heterozygous Newborn with Disorders of Sex Development First Identified in Vietnam by Phan Tuong Quynh Le, Thanh Nha Uyen Le, Thi Thanh Binh Nguyen, Minh Thao Nguyen, Thi Minh Thi Ha

“…Our finding has enriched the understanding of the spectrum of SRD5A2 variants and phenotypic correlation in Asian patients with 46,XY DSD.…”
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Morphological and agronomic characteristics of winter rye cultivars in connection with their resistance to lodging by N. A. Nabatova, E. S. Parfenova, E. I. Utkina, M. G. Shamova, E. A. Psareva, M. N. Zhukova

“…Searching for source material to breed non-lodging high-yielding cultivars requires studying the varietal phenotypic diversity according to morphological characters of the stem that affect the resistance to lodging and the productivity of the ear.Materials and methods. …”
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A review of hyperspectral image analysis techniques for plant disease detection and identif ication by A. F. Cheshkova

“…Further, the main areas of application of hyperspectral sensors in the diagnosis of plant diseases are considered, such as detection, differentiation and identif ication of diseases, estimation of disease severity, phenotyping of disease resistance of genotypes. A comprehensive review of scientif ic publications on the diagnosis of plant diseases highlights the benef its of hyperspectral technologies in investigating interactions between plants and pathogens at various measurement scales. …”
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Scientific provision of an effective development of soybean breeding and seed production in the Russian Far East by V. T. Sinegovskaya

“…Chaika” and biotechnologists carry out the selection of pairs for crossing using biotechnological methods to assess their polymorphism, instead of long-term selection for phenotypic features in the field. Evaluation of domestic and foreign varieties for disease resistance revealed a high degree of damage to foreign varieties by dangerous viral and fungal diseases. …”
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Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study by Feng S, Wang Y, Liu S, Zhang Y, He L

“…This study aims to explore these relationships using Mendelian Randomization (MR) analysis.Methods: Data from 191 resting-state functional MRI (rsfMRI) phenotypes and endometriosis genetic datasets were analyzed using both forward and reverse MR approaches. …”
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Distribution and frequency of genetic mutations in three insecticide targets in field populations of Culex tritaeniorhynchus in Mianyang City, Sichuan Province, China by Hongwei Xie, Meilin Tang, Hongying Sun, Zhengzheng Huang, Mengmeng Dong, Xianying Wen

“…Overall, the prevalent co-existence of resistance-conferring mutations in multiple insecticide target proteins in Cx. tritaeniorhynchus populations in Mianyang City indicates a worrying status of insecticide resistance, and suggests that it is highly required to monitor the phenotypic resistance of Cx. tritaeniorhynchus on a regular basis.…”
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