Phenogenetics of cortical granule dynamics during zebrafish oocyte-to-embryo transition by Priscila García-Castro, Isabella Giambó-Falian, Ingrid Carvacho, Ricardo Fuentes

“…The study of how genetic variations lead to observable phenotypes (phenogenetics) during the oocyte-to-embryo transition, have identified several maternal-effect genes in zebrafish involved in CG behavior. …”
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Double trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years by Almorò Scarpa, Riccardo Pianezza, Hannah R. Gellert, Anna Haider, Bernard Y. Kim, Eric C. Lai, Robert Kofler, Sarah Signor

“…Our work reveals that cascades of TE invasions, likely initiated by human-mediated range expansions, could have an impact on the genomic and phenotypic evolution of geographically dispersed species. …”
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Different Breeding Values Under Uniform Environmental Condition for Milk Production Yield Traits in Holstein-Friesian Cows by László Bognár, Zsolt Jenő Kőrösi, István Anton, Szabolcs Bene, Ferenc Szabó

“…Correlation and regression analysis were used to study the association between the phenotypic performance and the results of three different estimation models. …”
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Gene metabolite relationships revealed metabolic adaptations of rice salt tolerance by Mojdeh Akbarzadeh Lelekami, Mohammad Hadi Pahlevani, Khalil Zaynali Nezhad, Keyvan Mahdavi Mashaki

“…This study examined the effects of high salinity on the roots and shoots of rice genotypes with contrasting tolerances: CSR28 (tolerant) and IR28 (sensitive) at the seedling stage. Our phenotypic and physiological assessments indicated significant differences in response to prolonged salinity exposure between the two genotypes. …”
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Involvement of Toll -like receptor 9 signaling in neutrophil extracellular traps-induced epithelial-to-mesenchymal transition in myositis-associated interstitial lung disease by Feng Yingyue, Zhuo Cui, Su Qiyan, Cui Xi, Guo Jin, Zhu Jiarui, Zhang Sigong

“…Methods An experimental autoimmune myositis (EAM) mouse model was used, using histological and serological methods to clearly define the presence of NETs infiltration, EMT phenotypes, and TLR9 activation in IIM-ILD. In vitro, A549 cells were treated with NETs, and methods such as transcriptome sequencing, immunofluorescence, and Western blotting were used to investigate the mechanisms underlying NETs-induced EMT. …”
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Isolation and Characterization of Paracoccus sp. GSM2 Capable of Degrading Textile Azo Dye Reactive Violet 5 by Mallikarjun C. Bheemaraddi, Santosh Patil, Channappa T. Shivannavar, Subhashchandra M. Gaddad

“…The 16S rDNA sequence and phenotypic characteristics indicated an isolated organism as Paracoccus sp. …”
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MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication by Jonathan Cahn, Michael Regulski, Jason Lynn, Evan Ernst, Cristiane de Santis Alves, Srividya Ramakrishnan, Kapeel Chougule, Sharon Wei, Zhenyuan Lu, Xiaosa Xu, Umamaheswari Ramu, Jorg Drenkow, Melissa Kramer, Arun Seetharam, Matthew B. Hufford, W. Richard McCombie, Doreen Ware, David Jackson, Michael C. Schatz, Thomas R. Gingeras, Robert A. Martienssen

“…MaizeCODE deploys ENCODE strategies to catalog regulatory regions in the maize genome, generating histone modification and transcription factor ChIP-seq in parallel with transcriptomics datasets in 5 tissues of 3 inbred lines which span the phenotypic diversity of maize, as well as the teosinte inbred TIL11. …”
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Glomus Tumor of the Stomach: A Rare Cause of Upper Gastrointestinal Bleeding by Enzo Fabrício Ribeiro Nascimento, Fábio Piovezan Fonte, Roberta Laís Mendonça, Ronaldo Nonose, Carlos Alberto Fonte de Souza, Carlos Augusto Real Martinez

“…The majority of intraperitoneal glomus tumors occur in the stomach, and it is phenotypically similar to those localized in peripheral sites. …”
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MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2 by Kang Wei, Chuankun Zhou, Zixing Shu, Xingru Shang, Yi Zou, Wei Zhou, Huanhuan Xu, Yulin Liang, Tian Ma, Xuying Sun, Jun Xiao

“…Conversely, downstream RIPK2 significantly increased OA-like phenotypes and activated the NF-κB and MAPK pathways. …”
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Frequency and antibiotic resistance pattern of Salmonella spp. isolated from traditional dairies and raw milks collected in Yazd province, Iran by Raziyeh Barzegar-Bafrouei, Bahador Hajimohammadi, Hengameh Zandi, Gilda Eslami, Hossein Fallahzadeh

“…Following culturing the samples, isolates went through biochemical tests for phenotypic identification. Results were confirmed through PCR technique by targeting invA gene. …”
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Modern approaches to production of safe and effective genetically modified rabies vaccines for animals by M. I. Doronin, A. Mazloum, D. V. Mikhalishin, M. N. Mitrofanova, A. Yu. Sukharkov, V. V. Kiseleva, A. V. Sprygin

“…It provides new approaches to study functions of a specific gene by analyzing phenotypic effects after direct manipulations with nucleotide sequences. …”
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Replication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population by Nam Hee Kim, Young Jin Kim, Ji Hee Oh, Yoon Shin Cho

“…Pulse rate is known to be related to diverse phenotypes, such as cardiovascular diseases, lifespan, arrhythmia, hypertension, lipids, diabetes, and menopause. …”
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Genome-wide association study (GWAS) uncovers candidate genes linked to the germination performance of bread wheat (Triticum aestivum L.) under salt stress by Saeideh Javid, Mohammad Reza Bihamta, Mansour Omidi, Ali Reza Abbasi, Hadi Alipour, Pär K. Ingvarsson, Peter Poczai

“…Conclusion These findings, including the candidate genes, respective pathways, marker-trait associations (MTAs), and in-depth phenotyping of wheat accessions, improve knowledge of the mechanisms responsible for better germination performance of wheat seedlings under salinity conditions.…”
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Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies by J. Kimble Frazer, Lance A. Batchelor, Diana F. Bradley, Kim H. Brown, Kimberly P. Dobrinski, Charles Lee, Nikolaus S. Trede

“…In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Using array comparative genomic hybridization (aCGH), a technique to detect numeric variations between different DNA samples, we examined genomes from zebrafish (Danio rerio) T-cell leukemias of three cancer-prone lines. …”
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Time to Exhale: Additional Value of Expiratory Chest CT in Chronic Obstructive Pulmonary Disease by Joshua Gawlitza, Frederik Trinkmann, Hans Scheffel, Andreas Fischer, John W. Nance, Claudia Henzler, Nils Vogler, Joachim Saur, Ibrahim Akin, Martin Borggrefe, Stefan O. Schoenberg, Thomas Henzler

“…Thus, an additional expiratory CT may improve image-based phenotyping of patients with COPD.…”
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Spinal cord injury induces transient activation of hepatic stellate cells in rat liver by Inmaculada Fernandez-Canadas, Alejandro Badajoz, Jesús Jimenez-Gonzalez, Martin Wirenfeldt, Beatriz Paniagua-Torija, Clara Bravo-Jimenez, Mar Del Cerro, Angel Arevalo-Martin, Daniel Garcia-Ovejero

“…This is followed by a morphological and phenotypical transformation into alpha-smooth muscle actin (ACTA2/SMA) immunoreactive myofibroblast-like cells, peaking at 14 days post-injury and returning to control-like levels at later timepoints (45 days post-injury). …”
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A deep learning method for differentiating safflower germplasm using optimal leaf structure features by Hoang Thien Van, Phuong Thuy Khuat, Trang Van, Thai Thanh Tuan, Yong Suk Chung

“…These findings demonstrate that leaf image analysis is an effective and affordable tool for investigating the phenotypic diversity among safflower cultivars. This study highlights the potential of OLSF-ViT in automatic plant classification, and the results can be used in plant science, herbal medicine, and biodiversity conservation.…”
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Label-free proteomic analysis of Duchenne and Becker muscular dystrophy showed decreased sarcomere proteins and increased ubiquitination-related proteins by Juliana Cristina Tobar da Silva, Mariângela Rangel Alves Nogueira, Yara Martins da Silva, Fábio César Sousa Nogueira, Nathalie Henriques Silva Canedo, Katia Carneiro, Denise de Abreu Pereira

“…Enrichment of functions associated with cell structure and RNA binding was also observed, including cytoskeletal protein binding and RNA binding. The human phenotypes most related to the proteomic signature were abnormal circulating metabolites, muscle physiology, and weakness. …”
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The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1 by Payal Khandelwal, Mythili K. Padala, John Cox, Ramareddy V. Guntaka

“…Additional deletion analysis indicated that as few as 26 amino acids of the N-terminus of YB-1 can cause these phenotypic changes. We further demonstrated that this N-terminal 77 amino acid domain of YB-1 sequesters cyclin D1 in the cytoplasm of cells at G2/M phase of cell cycle. …”
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A Cocktail Method for Promoting Cardiomyocyte Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells by Qing Gao, Maojuan Guo, Xijuan Jiang, Xiantong Hu, Yijing Wang, Yingchang Fan

“…A cocktail method was designed: we investigated the role of 5-azacytidine (5-aza), salvianolic acid B (SalB), and cardiomyocyte lysis medium (CLM) in inducing MSCs to acquire the phenotypical characteristics of cardiomyocytes. The fourth-passage MSCs were treated with 5-aza, SalB, CLM, 5-aza+salB, 5-aza+CLM, SalB+CLM, and 5-aza+SalB+CLM for 2 weeks. …”
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