Identifying depression subtypes and investigating their consistency and transitions in a 1-year cohort analysis. by Carolin Oetzmann, Nicholas Cummins, Femke Lamers, Faith Matcham, Sara Siddi, Katie M White, Josep Maria Haro, Srinivasan Vairavan, Brenda W J H Penninx, Vaibhav A Narayan, Matthew Hotopf, Ewan Carr

“…Subtyping offers a way to unpick this phenotypic diversity for improved disorder characterisation. …”
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Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis. by Laura Garcia-Toscano, Heather N Currey, Joshua C Hincks, Jade G Stair, Nicolas J Lehrbach, Nicole F Liachko

“…Aggregated, phosphorylated TDP-43 may contribute to disease phenotypes; alternatively, TDP-43 aggregation may be a protective cellular response sequestering toxic protein away from the rest of the cell. …”
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Dual RNA-seq reveals transcriptome changes during Fusarium virguliforme-Trichoderma afroharzianum interactions. by Mirian F Pimentel, Leonardo F Rocha, Arjun Subedi, Jason P Bond, Ahmad M Fakhoury

“…This study focuses on elucidating the mechanisms underlying observed phenotypic differences among the T. afroharzianum isolates Th19A and Th4 during confrontation with Fusarium virguliforme by investigating differences in their transcriptome at different stages of interaction. …”
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Exploring the genetic profiles linked to senescence in thyroid tumors: insights on predicting disease progression and immune responses by Baoliang Zhang, Yanping Pang

“…Kaplan-Meier survival curves were plotted, and Receiver Operating Characteristic (ROC) curves rigorously confirmed the accuracy of model predictions.ResultsTo evaluate the predictive power of prognostic models across different phenotypic traits, we performed survival analysis, Gene Set Enrichment Analysis (GSEA), and immune-related differential analysis. …”
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Breeding for disease resilience: opportunities to manage polymicrobial challenge and improve commercial performance in the pig industry by Xuechun Bai, Graham S. Plastow

“…The next steps for managing polymicrobial challenges faced by the pig industry will include the development of large-scale multi-omics data, new phenotyping technologies, and mathematical and statistical methods adapted to these data. …”
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Morphometric analysis revealed two different Mediterranean horse mackerel (Trachurus mediterraneus) stocks in the Adriatic Sea by Claudio Vasapollo

“…Phenotypical differentiation among individuals of Mediterranean horse mackerel Trachurus mediterraneus in the Adriatic Sea was investigated through the analysis of several morphometric characters. …”
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Antimicrobial resistance profile among bacteria isolated from patients presenting with wounds at Kabale Regional Referral Hospital, South western Uganda by Andrew, Baguma, Benson, Musinguzi, Kagirita, Atek Atwiine, Joel, Bazira

“…In this study we emphasized on phenotypic characterization of bacteria that cause wound infections at Kabale Regional Hospital (KRRH) and determining the respective antimicrobial susceptibility profiles. …”
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A Multiplex High-Resolution Melting (HRM) assay to differentiate Fusarium graminearum chemotypes by Lovepreet Singh, Milton T. Drott, Hye-Seon Kim, Robert H. Proctor, Susan P. McCormick, J. Mitch Elmore

“…Isolates of F. graminearum can differ in trichothecene production phenotypes (chemotypes), with individuals producing predominantly one of four toxins: 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, nivalenol, or NX-2. …”
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Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination? by Jonah Clegg, Jonah Clegg, Malgorzata E. Mnich, Malgorzata E. Mnich, Alberto Carignano, Giovanni Cova, Simona Tavarini, Chiara Sammicheli, Bruna Clemente, Megan Smith, Megan Smith, Emilio Siena, Monia Bardelli, Michela Brazzoli, Fabio Bagnoli, Rachel M. McLoughlin, Elisabetta Soldaini

“…Due to colonizing interactions, pre-existing S. aureus-specific CD4+ T cells are often found in the human population and yet a detailed characterization of their phenotypes and how they might in turn impact vaccine efficacy are thus far unknown. …”
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Combined Klippel-Feil syndrome, Sprengel deformity, and diffuse large B-cell lymphoma: A rare case report by Golnaz Lotfian, MD, Amirmasoud Negarestani, MD, Sarah Gondek, BS, Aleksandr Raskind, DO, William Chen, MD, Emad Allam, MD

“…Klippel-Feil syndrome (KFS) is a rare congenital disorder characterized by the fusion of cervical vertebrae, with a clinical presentation that can vary widely due to genetic and phenotypic diversity. While KFS can occur as an isolated anomaly, it is often associated with other congenital conditions, such as Sprengel deformity, which may present with or without an omovertebral bone, complicating diagnosis and management. …”
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Redundant Vasodilator Pathways Underlying Radial Artery Flow-Mediated Dilation Are Preserved in Healthy Aging by Kevin D. Ballard, Michael E. Tschakovsky, Amanda L. Zaleski, Donna M. Polk, Paul D. Thompson, Francis J. Kiernan, Beth A. Parker

“…NO or PN blockade did not consistently reduce FMD in healthy older adults, suggesting the existence of redundant vasodilator phenotypes as observed previously in young adults.…”
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An Egyptian child with Wolman disease presenting with hemophagocytic lymphohistiocytosis by Rabab El Hawary, Safa Meshaal, Alia S. Eldash, Sohilla Lotfy, Dalia Abd Elaziz, Radwa Alkady, Rania Darwish, Aya Erfan, Mai Saad, Engy Chohayeb, Nermeen Galal, Aisha M. Elmarsafy

“…Wolman disease (WD) and cholesteryl ester storage disease (CESD) are two phenotypes of the same disorder with low or absent LAL activity. …”
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Measles Virus: Identification in the M Protein Primary Sequence of a Potential Molecular Marker for Subacute Sclerosing Panencephalitis by Hasan Kweder, Michelle Ainouze, Joanna Brunel, Denis Gerlier, Evelyne Manet, Robin Buckland

“…Hypothesizing that this phenotypic difference could potentially be represented by a molecular marker, we compared glycoprotein and matrix (M) genes from SSPE cases with those from the Moraten vaccine strain, searching for differential structural motifs. …”
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples by HyoYoung Kim, Won Gi Yoo, Junhyung Park, Heebal Kim, Byeong-Chul Kang

“…A semantic network is needed for in-depth understanding of the impacts of SNPs, because phenotypes are modulated by complex networks, including biochemical and physiological pathways. …”
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Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models by Anna MP. Stanger, Marlon Arnone, Pauline Hanns, Lucca M. Kimmich, Jessica Kübler, Sarah Gekeler, Elsa S. Görsch, Lea Kramer, Marcelle Baer, Jan C. Schroeder, Taylor S. Mills, Martina Konantz, Saskia S. Rudat, Claudia Lengerke

“…Adverse risk AML furthermore showed higher percentages of phenotypic leukemic stem cells (LSCs), suggesting impaired differentiation capacity in these AML subtypes. …”
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Heritability and Genetic Advance among Chili Pepper Genotypes for Heat Tolerance and Morphophysiological Characteristics by Magaji G. Usman, M. Y. Rafii, M. R. Ismail, M. A. Malek, Mohammad Abdul Latif

“…Yield per plant showed strong to moderately positive correlations (r=0.23–0.56) at phenotypic level while at genotypic level correlation coefficient ranged from 0.16 to 0.72 for CMT, plant height, fruit length, and number of fruits. …”
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Long-Term Cultured Human Term Placenta-Derived Mesenchymal Stem Cells of Maternal Origin Displays Plasticity by Vikram Sabapathy, Saranya Ravi, Vivi Srivastava, Alok Srivastava, Sanjay Kumar

“…Flow analysis established bonafied MSCs phenotypic characteristics, staining positively for CD29, CD73, CD90, CD105 and negatively for CD14, CD34, CD45 markers. …”
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IFN-γ reprograms cardiac microvascular endothelial cells to mediate doxorubicin transport and influences the sensitivity of mice to doxorubicin-induced cardiotoxicity by Haoyu Ji, Wenya Ma, Xu Liu, Hongyang Chen, Yining Liu, Zhongyu Ren, Daohong Yin, Ao Cai, Zizhen Zhang, Xin Wang, Wei Huang, Leping Shi, Yanan Tian, Yang Yu, Xiuxiu Wang, Yang Li, Yu Liu, Benzhi Cai

“…Through surface-enhanced Raman spectroscopy and single-cell RNA sequencing, we explored the mechanisms underlying DIC phenotypic variations. In vitro and in vivo studies with small-molecule drugs were conducted. …”
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Sleep Breathing Disorders’ Screening Among Children Approaching Orthodontic Evaluation: A Preliminary Study by Marco Storari, Francesca Stramandinoli, Maurizio Ledda, Alberto Verlato, Alessio Verdecchia, Enrico Spinas

“…Risk factors included oral breathing, nasal obstruction, tonsillar hypertrophy, malocclusion, high Friedman scores, narrow palates, and positive Brouillette phenotypes, all showing significant correlations (<i>p</i> < 0.05). …”
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Deletion of bZIP Transcription Factor <i>PratfA</i> Reveals Specialized Metabolites Potentially Regulating Stress Response in <i>Penicillium raistrickii</i> by Anxin Zhang, Shu Zhang, Xinran Xu, Wen-Bing Yin

“…At present, the <i>OE⸬PratfA</i> strain showed no phenotypic or oxidative stress sensitivity differences compared to the wild-type strain. …”
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