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Compensatory synaptotagmin-11 expression conceals parkinson’s disease-like phenotypes in parkin knockout mice
Published 2025-02-01“…Therefore, this work not only elucidate a compensatory mechanism that accounts for the absence of overt PD phenotypes in parkin KO mice, but also contribute to the comprehensive understanding of the progression of PD, opening new avenues for the therapeutic treatment of PD.…”
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303
Case report: FGF4L1 retrogene insertion is lacking in the tall dachshund phenotype
Published 2025-01-01“…Two retrogene insertions, FGF4L1 (formerly 18-FGF4, colloquially CDPA) and FGF4L2 (formerly 12-FGF4, colloquially CDDY), have recently been discovered as determinants of short leg phenotype in dogs. This case study is comprised of a family of standard wirehaired dachshunds in which the dogs lacking the FGF4L1 gene exhibit a tall phenotype. …”
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Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes
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Prevalence of “weak B” phenotypes and their evaluation and differentiation in healthy blood donor population in Eastern India
Published 2024-12-01Subjects: Get full text
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c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes
Published 2012-01-01“…Previous toxicogenomic studies have demonstrated that cyclosporine- (CsA-) induced epithelial phenotypic changes (EPCs) are reminiscent of an incomplete epithelial to mesenchymal transition (EMT) in a TGF-β-independent manner. …”
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309
Identification of CD8+ T Cell-Related Genes: Correlations with Immune Phenotypes and Outcomes of Liver Cancer
Published 2021-01-01“…Because the factors in the coexpression network often participate in similar biological processes, we found that these factors were most related to antigen processing and presentation of peptide antigen through functional enrichment. In the clinical phenotype analysis, we found that 18 factors can be used as independent prognostic protective factors. …”
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Characterization of indigenous chicken phenotypes in Liban Jawi District, Ethiopia: A qualitative and quantitative analysis.
Published 2025-01-01“…This study aimed to phenotypically characterize indigenous chickens in the Liban Jawi district, focusing on measurements of phenotypic characteristics. …”
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Mutational Profile and Retinal Phenotypes of PCARE-Related Cone-Rod Dystrophies in a Mexican Cohort
Published 2024-01-01“…The aim of the study is to describe the genotype and phenotype of a Mexican cohort with PCARE-related retinal disease. …”
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Epithelial-Mesenchymal Transition Phenotype, Metformin, and Survival for Colorectal Cancer Patients with Diabetes Mellitus II
Published 2017-01-01“…We aimed to explore the association between metformin treatment and epithelial-mesenchymal transition (EMT) phenotype and further appraise the prognostic values of metformin and EMT markers E-cadherin and vimentin for colorectal cancer (CRC) in clinical practice. …”
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Sex differences in cognition, anxiety-phenotype and therapeutic effect of metformin in the aged apoE-TR mice
Published 2025-01-01“…Metformin improves the spatial memory of female, but not male apoE3-TR mice and female apoE4-TR mice while aggravating the cognitive impairment of male apoE4-TR mice. The anxiety-like phenotypes in male apoE4-TR mice are more severe than in male apoE3-TR mice, while metformin ameliorates the anxiety-like behaviors in the male apoE4-TR mice but not in male apoE3-TR mice. …”
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Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer’s disease: a neuropsychological data-driven approach
Published 2025-02-01Subjects: Get full text
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Inhaled corticosteroids in asthma and chronic obstructive pulmonary disease combined phenotype: when to use and what to expect?
Published 2025-01-01Subjects: “…Asthma-COPD combined phenotype…”
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317
Animal as the Solution II: Phenotyping for Low Milk Urea Nitrogen A1PF Dairy Cows
Published 2024-12-01“…Our results suggest that A1PF cows within a commercial herd can be phenotyped and selected for low-MUN, which may be potentially a viable strategy to reduce N losses to the environment and create healthier systems. …”
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TRANSFER OF ARGOS-LIKE AND ATEXPA10 GENES INTO NONTRANSGENIC FORMS OF TOBACCO AND PHENOTYPIC EFFECTS OF THEIR CONSTITUTIVE EXPRESSION
Published 2014-12-01“…The inheritance was stable, but the phenotypic effects varied from insignificant to levels exceeding those in parental transgenic plants.…”
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Clinical, Radiographic, and Molecular Analysis of Patients with X-Linked Hypophosphatemic Rickets: Looking for Phenotype–Genotype Correlation
Published 2025-01-01Subjects: Get full text
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Phenotype and Function of CD25-Expressing B Lymphocytes Isolated from Human Umbilical Cord Blood
Published 2011-01-01“…B cells expressing CD25 display a mature phenotype belonging to the memory B-cell population and have a better proliferative and antigen-presenting capacity. …”
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