Photosymbiosis shaped animal genome architecture and gene evolution as revealed in giant clams by Ruiqi Li, Carlos Leiva, Sarah Lemer, Lisa Kirkendale, Jingchun Li

“…Abstract Symbioses are major drivers of organismal diversification and phenotypic innovation. However, how long-term symbioses shape whole genome evolution in metazoans is still underexplored. …”
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Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity. by Quanhui Dai, Kristina Preusse, Danni Yu, Rhett A Kovall, Konrad Thorner, Xinhua Lin, Raphael Kopan

“…To ask if HDAC2 activity contributes to Notch loss-of-function phenotypes, we used the HDAC2 inhibitor Valproic acid (VPA) and discovered it could prevent the intestinal consequences of NDD and gamma secretase inhibitors (DBZ or DAPT) treatment in mice and spheroids, suggesting synergy between HDAC activity and pro-differentiation program in intestinal stem cells.…”
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Characterization of Staphylococcus aureus Strains Isolated from Veterinary Hospital by Ariel E. Stella, Thaís F. Lima, Cecília N. Moreira, Eric M. N. De Paula

“…Four strains harbor the mecA gene; however, only two expressed the phenotypic resistance to cefoxitin and were characterized as MRSA. …”
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Productive capacity and genetic variation behavior in progenies from irrigated açai according to plant age by João Tomé de Farias Neto, Gilberto Ken Iti Yokomizo, Marcos Deon Vilela de Resende

“…Therefore, the objective of this work was to infer the best age for selection by estimating genetic and phenotypic parameters in the different stages of evaluating progenies of half-sibs of acai. …”
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Evaluation of the genome in bird breeding by A. F. Yakovlev, N. V. Dement’eva

“…The improvement of the separate stages of genome selection will be helped by perfection of registration and mathematical treatment of the phenotypical and molecular database, imputation and estimations of linkage disequilibrium.…”
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Unique Aspects of Cryptochrome in Chronobiology and Metabolism, Pancreatic β-Cell Dysfunction, and Regeneration: Research into Cysteine414-Alanine Mutant CRY1 by Satoshi Okano

“…Transgenic mice (Tg mice), ubiquitously expressing mouse CRY1 having a mutation in which cysteine414 (the zinc-binding site of CRY1) being replaced with alanine, display unique phenotypes in their circadian rhythms. Moreover, male Tg mice exhibit symptoms of diabetes characterized by beta-cell dysfunction, resembling human maturity onset diabetes of the young (MODY). …”
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RNA-Binding Proteins in Amyotrophic Lateral Sclerosis and Neurodegeneration by Scott E. Ugras, James Shorter

“…In a recent study, Couthouis et al. screened for protein candidates that were also involved in RNA processing, contained a predicted prion domain, shared other phenotypic similarities with TDP-43 and FUS, and identified TAF15 as a putative ALS gene. …”
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Evidence of the Complexity of Gene Expression Analysis in Fish Wild Populations by Mbaye Tine

“…Although significant, the correlations between gene expression and salinity were slightly ambiguous and did not show any link with phenotypic differences in life history traits previously reported between the same populations. …”
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Mistakes in the diagnosis and treatment of atopic dermatitis by Monika Marko, Rafał Pawliczak

“…It is easy to make mistakes during the diagnosis and treatment of AD due to the complex clinical picture of the disease and the diversity of phenotypes. Obstacles can also be encountered during differential diagnosis. …”
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Precision medicine using molecular-target drugs in psoriatic arthritis by Ippei Miyagawa, Yoshiya Tanaka

“…Recently, the strategic use of molecular-targeted drugs based on the stratification of patients with PsA by peripheral blood lymphocyte phenotyping and serum cytokine concentrations has been reported to possibly lead to a higher therapeutic response. …”
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Growth and Decay of a Planktonic Microbial Culture by Alberto Schiraldi

“…Deviations of such a trend concern microbes able to form spores, modify their metabolism, or express phenotypic heterogeneity, to counterbalance adverse medium conditions.…”
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State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research by Anna-Sophia Wahl

“…However, only minor attempts have been made to connect distinct plastic remodeling processes as causative features for specific behavioral phenotypes. Here, we review current state-of the art techniques for the examination of cortical reorganization and for the manipulation of neuronal circuits as well as techniques which combine anatomical changes with molecular profiling. …”
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African swine fever: one hundred years later by V. V. Makarov

“…In addition to the gaps mentioned in these conclusions and recommendations there are serious gaps in African swine fever immunology, namely in protective immunity mechanisms, virus-macrophage interaction, in vitro virus phenotypic  signs correlating with its virulence, etc. …”
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Molecular detection of pore-forming leuko toxin in methicillin resistant Staphylococcus aureus isolated from skin infection by Sara A. Al-Ghazal, Huda H. Al-Hassnawi

“…Results: All isolates were determined to be resistant to cefoxitin discs and oxacillin by using phenotypic analysis, and a genotypic investigation revealed that 79.16% of them carried the mecA gene. …”
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Mentiras humanas y mentiras animales. Sobre los límites de la comunicación by Enrique del Teso Martín

“…Lorenzo en Computational Phenotypes. …”
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The Distribution of Activation Markers and Selectins on Peripheral T Lymphocytes in Preeclampsia by Anna Bajnok, Maria Ivanova, János Rigó, Gergely Toldi

“…Impaired maternal immune tolerance resulting in systemic inflammation plays a pivotal role in the pathogenesis of preeclampsia. Phenotypical changes of monocytes and neutrophil granulocytes have already been studied in preeclampsia, and some studies also included T lymphocyte activation markers; however, the results are controversial and a comprehensive analysis of activation markers is lacking. …”
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Role of Helicobacter pylori in the Pathogenesis of Gastric Carcinoma and Progression of Lymphoid Nodules to Lymphoma by M Guindi

“…Investigation of early gastric carcinomas concluded that two main pathways operated in gastric carcinogenesis, both starting from H pylori gastritis and leading to phenotypically variable gastric or intestinal tumour growth. …”
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Effector, Memory, and Dysfunctional CD8+ T Cell Fates in the Antitumor Immune Response by John Reiser, Arnob Banerjee

“…These interactions and signals can lead to transcriptional, functional, and phenotypic changes in TILs that diminish the host’s ability to eradicate the tumor. …”
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Emerging Paradigms in Genomics-Based Crop Improvement by Abhishek Bohra

“…Furthermore, rapid generation of genome-wide marker data coupled with easy access to precise and accurate phenotypic screens enable large-scale exploitation of LD not only to discover novel QTLs via whole genome association scans but also to practise genomic estimated breeding value (GEBV)-based selection of genotypes. …”
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Differentiation of mesenchymal stem cells towards lens epithelial stem cells based on three-dimensional bio-printed matrix by Yufan Liu, Zuowei Wang, Tianju Ma, Yi Gao, Wenqian Chen, Zi Ye, Zhaohui Li

“…Loaded MSCs in the matrix were consistently upregulated in the expression of proteins and genes involved in phenotypes and development signaling pathways of LESCs, as detected by polymerase chain reaction (PCR) with the support of biochemical cues. …”
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