Two novel species of Aspergillus section Nigri from indoor air by Željko Jurjević, Stephen W. Peterson, Gaetano Stea, Michele Solfrizzo, János Varga, Vit Hubka, Giancarlo Perrone

“…To describe the species we used phenotypes from 7-d Czapek yeast extract agar culture (CYA), creatine agar culture (CREA) and malt extract agar culture (MEA), with support by molecular analysis of the β-tubulin, calmodulin, RNA polymerase II (RPB2), and translation elongation factor-alpha (TEF) gene amplified and sequenced from 56 air isolates and one isolate from almonds belonging to Aspergillus section Nigri. …”
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mTOR Inhibition: From Aging to Autism and Beyond by Matt Kaeberlein

“…Although overly simplistic, this framework can be useful when considering the myriad functions ascribed to mTOR and the pleiotropic phenotypes associated with genetic or pharmacological modulation of mTOR signaling. …”
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Network-assisted target identification for haploinsufficiency and homozygous profiling screens. by Sheng Wang, Jian Peng

“…With the drug-induced phenotypic fitness defect of the deletion of a gene, GIT also incorporates the fitness defects of the gene's neighbors in the genetic interaction network. …”
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Palmoplantar plaque psoriasis responsive to upadacitinib: A report of two cases by Bohmyi Choi, Heidi Oi-Yee Li, Steven J Glassman

“…Palmoplantar plaque psoriasis is more resistant to therapy compared to other phenotypes of psoriasis. To our knowledge, there are no reports of the efficacy of Janus kinase (JAK) inhibitors for palmoplantar plaque psoriasis. …”
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Alternative Splicing Programs in Prostate Cancer by Claudio Sette

“…Although the initial antiandrogenic therapies are efficacious, PCa often evolves into a hormone-resistant, incurable disease. The genetic and phenotypic heterogeneity of this type of cancer renders its diagnosis and cure particularly challenging. …”
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Diagnosing Growth Hormone Deficiency in Adults by Nigel Glynn, Amar Agha

“…Adult growth hormone (GH) deficiency is a recognised syndrome associated with adverse phenotypic, metabolic, and quality-of-life features which improve in many patients when GH is substituted. …”
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Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii) by Alfonso Baldi, Andrea Lanza, Francesco Menicagli, Pietro G. Signorile, Enrico P. Spugnini

“…We suggest considering endometriosis among the other pathological phenotypes in animals displaying ovarian and uterine alterations and having a history of difficulties in conceiving.…”
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Genetic Diversity of Upland Rice Germplasm in Malaysia Based on Quantitative Traits by M. Sohrabi, M. Y. Rafii, M. M. Hanafi, A. Siti Nor Akmar, M. A. Latif

“…The higher magnitudes of genotypic and phenotypic coefficients of variation were recorded for flag leaf length-to-width ratio, spikelet fertility, and days to flowering. …”
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Small variant benchmark from a complete assembly of X and Y chromosomes by Justin Wagner, Nathan D. Olson, Jennifer McDaniel, Lindsay Harris, Brendan J. Pinto, David Jáspez, Adrián Muñoz-Barrera, Luis A. Rubio-Rodríguez, José M. Lorenzo-Salazar, Carlos Flores, Sayed Mohammad Ebrahim Sahraeian, Giuseppe Narzisi, Marta Byrska-Bishop, Uday S. Evani, Chunlin Xiao, Juniper A. Lake, Peter Fontana, Craig Greenberg, Donald Freed, Mohammed Faizal Eeman Mootor, Paul C. Boutros, Lisa Murray, Kishwar Shafin, Andrew Carroll, Fritz J. Sedlazeck, Melissa Wilson, Justin M. Zook

“…Abstract The sex chromosomes contain complex, important genes impacting medical phenotypes, but differ from the autosomes in their ploidy and large repetitive regions. …”
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Dendritic Cells and Their Multiple Roles during Malaria Infection by Kelly N. S. Amorim, Daniele C. G. Chagas, Fernando B. Sulczewski, Silvia B. Boscardin

“…Different groups have shown that DCs act during Plasmodium infection, and data suggest that the phenotypically distinct DCs subsets are key factors in the regulation of immunity during infection. …”
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EFFECT OF REARRANGEMENTS OF HOMOEOLOGOUS GROUP 2 CHROMOSOMES OF BREAD WHEAT ON SPIKE MORPHOLOGY by O. B. Dobrovol’skaya, P. Martinek, I. G. Adonina, E. D. Badaeva, Yu. L. Orlov, E. A. Salina, L. I. Laikova

“…Evaluations of spike phenotypes of the line with the supernumerary spikelet trait and Chinese Spring deletion lines carrying deletions of chromosomes 2A, 2B, and 2D demonstrated that deletion of a group 2 chromosome might alter spike morphology, resulting in development of supernumerary spikelets at rachis nodes and changes in spike length and density.…”
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Signaling pathway mechanisms of circadian clock gene Bmal1 regulating bone and cartilage metabolism: a review by Yiting Ze, Yongyao Wu, Zhen Tan, Rui Li, Rong Li, Wenzhen Gao, Qing Zhao

“…Deletion of the core clock gene Bmal1 leads to pathological bone alterations, while the phenotypes are not consistent. Studies have shown that multiple signaling pathways are involved in the process of Bmal1 regulating bone and cartilage metabolism, but the exact regulatory mechanisms remain unclear. …”
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Desmin‐related myopathy characterized by non‐compaction cardiomyopathy, cardiac conduction defect, and coronary artery dissection by Ran Tamiya, Yuki Saito, Daisuke Fukamachi, Koichi Nagashima, Yoshihiro Aizawa, Kimie Ohkubo, Takumi Hatta, Akira Sezai, Masashi Tanaka, Taisuke Ishikawa, Naomasa Makita, Naokata Sumitomo, Yasuo Okumura

“…However, the clinical cardiac phenotypes of DRM are not yet fully understood. Herein, we report the first case of DRM with the de novo missense DES mutation, R454W, that is characterized by left ventricular non‐compaction cardiomyopathy, progressive cardiac conduction defect, spontaneous coronary artery dissection, and no skeletal muscle weakness. …”
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Research progress of artificial intelligence in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer by Wei Wei, Menghang Ma, Zhenyu Liu

“…The evolution of artificial intelligence (AI) technologies has precipitated the delineation and quantification of imaging-based phenotypic features, thereby translating these structural modifications into quantifiable data alterations. …”
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Complete Morris Syndrome. Case Presentation by Manyeles Brito Vázquez, Ángela Belkis Brito García, Delvis Batista García

“…Androgen insensitivity syndrome, Morris syndrome or testicular feminization is a disorder in sexual differentiation, in which the individual is phenotypically feminine, but with a man's genetic characteristics. …”
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Association Analysis of ULK1 with Crohn’s Disease in a New Zealand Population by Angharad R. Morgan, Wen-Jiun Lam, Dug-Yeo Han, Alan G. Fraser, Lynnette R. Ferguson

“…In this sample, we were able to demonstrate an association between CD and several different ULK1 SNPs and haplotypes. Phenotypic analysis showed an association with age of diagnosis 17–40 years and inflammatory behaviour. …”
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Mitochondrial disease and epilepsy in children by Xuan Zhang, Xuan Zhang, Xuan Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Zhiming Tao, Zhiming Tao, Zhiming Tao, Jianmin Liang, Jianmin Liang, Jianmin Liang

“…This dysfunction can lead to a variety of clinical phenotypes, particularly affecting organs with high energy demands, such as the brain and muscles. …”
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The role of HEPCAM in Jacobsen syndrome: A pediatric case report highlighting white matter abnormalities by Ghazaleh Ghorbannezhad, Reza Nejad Shahrokh Abadi, Farrokh Seilanian Toosi, Shima Shekari, Saeedeh Sadat Mirtooni, Narges Hashemi

“…Jacobsen syndrome (JS) is a rare contiguous gene deletion disorder characterized by a deletion at the terminal end of the long arm of chromosome 11. JS has various phenotypic features, such as neurodevelopmental delays and congenital heart defects. …”
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Cytokine and Growth Factor Activation In Vivo and In Vitro after Spinal Cord Injury by Elisa Garcia, Jorge Aguilar-Cevallos, Raul Silva-Garcia, Antonio Ibarra

“…The excessive inflammatory Th1 and Th17 phenotypes observed after SCI tilt the scale towards a proinflammatory environment, which exacerbates the deleterious mechanisms present after the injury. …”
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Which Are the Cells of Origin in Merkel Cell Carcinoma? by Thomas Tilling, Ingrid Moll

“…Merkel cells (MCs), the neuroendocrine cells of the skin, were believed to be at the origin of MCC due to their phenotypic similarities. However, for several reasons, for example, heterogeneous differentiation of MCCs and postmitotic character of MCs, it is not very likely that MCC develops from differentiated MCs. …”
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