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2561
Evaluation of Panicle Exsertion and Identification of QTL for Long Panicle Neck in Single-segment Substitution Lines of Wild Rice
Published 2024-11-01“…Their average additive effect values were in the range of 1.74-4.08 cm, respectively, and the phenotypic contribution rates of the additive effects were 107.82%~481.80%. …”
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2562
Human leukocyte Antigen-B*27 allele subtype prevalence and disease association of ankylosing spondylitis among south indian population
Published 2018-01-01“…Early-onset of AS manifestations is seen in HLA B27 phenotypes than non-HLA B27 phenotypes. HLA B27 associated AS patients presented more severe axial manifestations such as bilateral sacroiliitis, erosions, and extra-articular features such as uveitis than non-HLA types. …”
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2563
Metabolic Activity in Human Intermuscular Adipose Tissue Directs the Response of Resident PPARγ<sup>+</sup> Macrophages to Fatty Acids
Published 2024-12-01“…Immunofluorescence analysis was used to detect macrophage phenotypes and mitochondrial activity. Preconfigured arrays were used to detect the expression of 34 different adipokines and chemokines. …”
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2564
Clinical and biochemical features of atherogenic hyperlipidemias with different genetic basis: A comprehensive comparative study.
Published 2024-01-01“…Patients with genetically-based hyperlipidemias exhibit a wide phenotypic variability. Investigation of clinical and biochemical features is important for identifying genetically-based hyperlipidemias, determining disease prognosis, and initiating timely treatment. …”
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2565
Novel candidate genes and genetic basis analysis of kernel starch content in tropical maize
Published 2025-01-01“…Results The integration of QTL mapping and genome-wide association analysis (GWAS) identified two SNPs, 8_166371888 and 8_178656036, which overlapped the QTL interval of qSC8-1, identified in the tropical maize line YML46. The phenotypic variance explained (PVE) by the QTL qSC8-1 was12.17%, while the SNPs 8_166371888 and 8_178656036 explained 10.19% and 5.72% of the phenotypic variance. …”
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2566
Airborne Escherichia coli bacteria biosynthesize lipids in response to aerosolization stress
Published 2025-01-01“…The biosynthesis of lipids, particularly lipopolysaccharides, or lipooligosaccharides (LPS/LOS) is essential for OM repair. Here we show the phenotypic and genotypic changes of Escherichia coli MG1655 (E. coli) before and after exposure to short-term aerosolization, 5 min, and long-term indoor aerosolization, 30 min. …”
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2567
Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia
Published 2023-08-01“…The taxonomy status of strain MUM 203JT was determined via a polyphasic approach comprising phenotypic observations, genomic and phylogenetic analyses, and chemotaxonomic analyses. …”
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2568
Detection of plasmids in Salmonella from poultry and investigating the potential horizontal transfer of antimicrobial resistance and virulence genes
Published 2025-01-01“…The ARGs and VGs on plasmids were identified by both VRprofile2 and oriTfinder. The phenotypes of ARGs were predicted by ResFinder 4.1 and oriTfinder, while the phenotypes of virulence were predicted by oriTfinder and VRprofile2. …”
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2569
Predominance of OXA-48 Carbapenemase-Producing Enterobacterales in a Moroccan Hospital
Published 2023-01-01“…Our study aimed at investigating the resistance of CPE isolates in a Moroccan teaching hospital using phenotypic and genotypic methods. Methods. Enterobacterales strains from March to June 2018 were collected from different clinical samples. …”
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2570
The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis
Published 2025-01-01“…The purpose of this study was to use Mendelian randomization (MR) analysis to investigate the causal relationship between smoking phenotypes and OA risk from a genetically informed standpoint.MethodsAs instrumental variables (IVs) based on single nucleotide polymorphisms (SNPs), this study used the summary-level data of corresponding genome-wide association study (GWAS) for five smoking phenotypes involving 1,694,781 samples. …”
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2571
Arising amitraz and pyrethroids resistance mutations in the ectoparasitic Varroa destructor mite in Canada
Published 2025-01-01“…The phenotypic resistance showed a significant correlation with the presence of this mutation across apiaries. …”
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2572
Current views on etiology, diagnosis, epidemiology and gene therapy of maturity onset diabetes in the young
Published 2025-01-01“…Furthermore, there is a lack of clear gene-phenotypic correlations, and there is quite satisfactory curability in the majority of patients. …”
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2573
An unbiased cell morphology-based screen for new, biologically active small molecules.
Published 2005-05-01“…This assay format provides unbiased analysis of morphological effects induced by small molecules by capturing phenotypic readouts of most known classes of pharmacological agents and has the potential to read out pathways for which little is known. …”
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2574
A clinical study exploring the prediction of microvascular invasion in hepatocellular carcinoma through the use of combined enhanced CT and MRI radiomics.
Published 2025-01-01“…After extracting 2153 imaging phenotyping features from the CT and MRI images of the 93 patients using Python, ten standardized coefficient non-zero imaging phenotyping features were finally determined by Lasso regression analysis in the CT and MRI images. …”
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2575
A conserved fungal Knr4/Smi1 protein is crucial for maintaining cell wall stress tolerance and host plant pathogenesis.
Published 2025-01-01“…Further studies confirmed the observed phenotypes are partially due to the involvement of FgKnr4 in regulating the fungal cell wall integrity pathway by modulating the phosphorylation of the MAP-kinase MGV1. …”
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2576
Clinical and Genetic Characteristics of ABCC8 Nonneonatal Diabetes Mellitus: A Systematic Review
Published 2021-01-01“…The variants in ABCC8 gene encoding the SUR1 subunit of KATP could cause a variety of phenotypes, including neonatal diabetes mellitus (ABCC8-NDM) and ABCC8-induced nonneonatal diabetes mellitus (ABCC8-NNDM). …”
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2577
Cerebrospinal fluid metabolites as potential biomarkers for epilepsy: Insights from genome‐wide association studies
Published 2025-02-01“…A total of 338 CSF metabolites were investigated as exposures, and 11 epilepsy phenotypes were examined as the outcomes. A two sample Mendelian randomization (MR) approach was utilized to explore the causal influence of these metabolites on epilepsy. …”
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2578
Single-cell transcriptomic profiling of heart reveals ANGPTL4 linking fibroblasts and angiogenesis in heart failure with preserved ejection fraction
Published 2025-02-01“…Furthermore, an increased number of fibroblasts differentiated into high-metabolism and high-fibrosis phenotypes. The expression levels of genes encoding certain pro-angiogenic secreted proteins were decreased in the HFpEF group, as confirmed by bulk RNA sequencing. …”
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2579
Why have tobacco control policies stalled? Using genetic moderation to examine policy impacts.
Published 2012-01-01“…Tobacco use phenotypes included current use, number of cigarettes smoked per day, and blood serum cotinine measurements.…”
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2580
The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization
Published 2023-01-01“…They can polarize into M1 or M2 functional phenotypes. These two phenotypes exhibit a dynamic balance during polarization-related diseases and play opposing roles. …”
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