Diverse Effects of Lead Nitrate on the Proliferation, Differentiation, and Gene Expression of Stem Cells Isolated from a Dental Origin by Mariam Abdullah, Fazliny Abd. Rahman, Nareshwaran Gnanasegaran, Vijayendran Govindasamy, Noor Hayaty Abu Kasim, Sabri Musa

“…There were no significant changes in terms of cell surface phenotypes. Cells exposed to Pb2+ continued to differentiate into chondrogenesis and adipogenesis, and a severe downregulation was observed in osteogenesis. …”
Get full text

Plastic responses for intercrop functioning by Franca J. Bongers, Jochem B. Evers, Niels P. R. Anten

“…Abstract Intercropping systems have large heterogeneity in canopy and soil conditions, which could induce phenotypic plasticity. We review different kinds of observed plasticity and to what extent these influence crop performance and outline the diversity of signals that could occur in intercrops. …”
Get full text

Molecular Detection of Pap II, OmpA, and LuxR Genes Responsible for Biofilm Formation in Acinetobacter baumannii Isolated from Hospitalized Patients by Estabraq Ali Maklef, Amal A. Kareem, Susan F. K. Al-Sudani

“…Biofilm formation was phenotypically investigated using the microtiter plate method. …”
Get full text

Individual and sex differences in frontloading behavior and approach- avoidance conflict preference predict addiction-like ethanol seeking in rats by Tanner A. McNamara, Hanyi Weng, Hsin Yu Liao, Rutsuko Ito

“…Our data highlight key sex differences, and the relevance of both frontloading patterns and conflict preference in predicting future addiction-like phenotypes.…”
Get full text

Genome-wide association study reveals major loci for resistance to septoria tritici blotch in a Tunisian durum wheat collection. by Maroua Ouaja, Bikash Ghimire, Bochra Amina Bahri, Medini Maher, Sahbi Ferjaoui, Sripada Udupa, Sonia Hamza

“…Using 7638 SNP markers, fifty-one marker-trait associations (MTAs) for STB resistance were identified by genome-wide association study (GWAS) at Bonferroni correction threshold of -log10(P) > 5.184 with phenotypic variance explained (PVE) reaching up to 58%. …”
Get full text

Accurate LAI estimation of soybean plants in the field using deep learning and clustering algorithms by Bing Shi, Luqi Guo, Lejun Yu

“…This indicates that the individual segmentation algorithm, Watershed-based approach combined with PointNet++, can serve as a crucial foundation for extracting high-throughput plant phenotypic data. The experimental results confirm that the proposed method can rapidly calculate the morphological parameters of each soybean plant, making it suitable for high-throughput soybean phenotyping.…”
Get full text

Uncovering the genetic basis of milk production traits in Mexican Holstein cattle based on individual markers and genomic windows. by José G Cortes-Hernández, Adriana García-Ruiz, Francisco Peñagaricano, Hugo H Montaldo, Felipe J Ruiz-López

“…A total of 162 markers were significantly associated (p<0.01) with the phenotypic traits evaluated, and the SNP markers were distributed across chromosomes 1, 3, 5, 6, 10, 12, 14, 16, 18, 20, 22, and 29. …”
Get full text

Evolution under intensive industrial breeding: skull size and shape comparison between historic and modern pig lineages by A. Haruda, A. Evin, F. Steinheimer, R. Schafberg

“…This also suggests that pig morphotypes quickly reflect human agency and impact upon domestic animal phenotypes, revealing a pathway to investigate early human breeding activity in ancient and historical contexts.…”
Get full text

New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications by Eva Sticova, Milan Jirsa, Joanna Pawłowska

“…Therefore, BRIC and PFIC seem to represent two extremes of a continuous spectrum of phenotypes that comprise one disease. Thus far, five representatives of PFIC (named PFIC1-5) caused by pathogenic mutations present in both alleles of ATP8B1, ABCB11, ABCB4, TJP2, and NR1H4 have been described. …”
Get full text

Morphological Characterization and Assessment of Genetic Variability, Character Association, and Divergence in Soybean Mutants by M. A. Malek, Mohd Y. Rafii, Most. Shahida Sharmin Afroz, Ujjal Kumar Nath, M. Monjurul Alam Mondal

“…Narrow differences between phenotypic and genotypic coefficients of variation (PCV and GCV) for most of the characters revealed less environmental influence on their expression. …”
Get full text

Unsupervised machine learning clustering approach for hospitalized COVID-19 pneumonia patients by Nuttinan Nalinthasnai, Ratchainant Thammasudjarit, Tanapat Tassaneyasin, Dararat Eksombatchai, Somnuek Sungkanuparph, Viboon Boonsarngsuk, Yuda Sutherasan, Detajin Junhasavasdikul, Pongdhep Theerawit, Tananchai Petnak

“…Abstract Background Identification of distinct clinical phenotypes of diseases can guide personalized treatment. …”
Get full text

Deficiency of ATF3 facilitates both angiotensin II‐induced and spontaneously formed aortic aneurysm and dissection development by activating cGAS–STING pathway by Yifan Du, Poyi Hu, Xiangchao Ding, Dashuai Wang, Jingjing Luo, Sheng Le, Lingyun Ren, Manhua Chen, Ping Ye, Jiahong Xia

“…However, the molecular mechanisms responsible for the phenotypic switch and loss of VSMCs in AAD are not fully understood. …”
Get full text

Association of Sociodemographic Factors With Overtriage, Undertriage, and Value of Care After Major Surgery by Tyler J. Loftus, MD, Matthew M. Ruppert, MS, Benjamin Shickel, PhD, Tezcan Ozrazgat-Baslanti, PhD, Jeremy A. Balch, MD, Kenneth L. Abbott, MD, Die Hu, MS, Adnan Javed, MD, Firas Madbak, MD, Faheem Guirgis, MD, David Skarupa, MD, Philip A. Efron, MD, Patrick J. Tighe, MD, William R. Hogan, MD, Parisa Rashidi, PhD, Gilbert R. Upchurch, Jr, MD, Azra Bihorac, MD

“…K-means clustering identified sociodemographic phenotypes within overtriage and undertriage cohorts. …”
Get full text

Assessing the Causal Relationship Between Various Immune Cells and Attention Deficit Hyperactivity Disorder: Mendelian Randomization Study by Qian Ge, Zhongyan Li, Weijing Meng, Chen Cai, Mengdi Qiu, Yafei Liu, Haibo Zhu

“…Immune cell phenotypes that may both increase and worsen the likelihood of having ADHD were identified by IVW results. …”
Get full text

Escherichia Coli: From Genome Sequences to Consequence by Mark Pallen

“…Professor Pallen's lecture, entitled 'Escherichia coli: From genome sequences to consequences', provides a summary of the important discoveries of his team of research scientists in the area of genetic sequencing and variations in phenotypic expression.…”
Get full text

Predicting Postoperative Re-Tear of Arthroscopic Rotator Cuff Repair Using Artificial Intelligence on Imbalanced Data by Zhibin Zhang, Zhewei Zhang, Zhaoxiang Peng, Yihong Dong

“…This paper employs a pairwise associative encoder (PAE) to construct edges, calculating similarity scores between different nodes to effectively handle the complementary relationship between phenotypic and non-phenotypic data. The other part is the weight network, which calculates the weights of different nodes of different classes to assign weights to the objective function through the GCN model. …”
Get full text

Small pieces make the big picture: the etiology of the relationship between executive functions and personality traits by Željka Nikolašević, Snežana Smederevac, Dušanka Mitrović, Petar Čolović, Bojana Dinić, Jasmina Kodžopeljić, Mechthild Prinz, Zoran Budimlija, Vojislava Bugarski Ignjatović

“…Abstract Background This study primarily aimed to explore the etiology of the phenotypic relationships between personality traits and executive functions. …”
Get full text

Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…This study utilized integrative bioinformatics’ tools together with phenotypic assays to understand the whole-genome features of a carbapenem-resistant international clone II Acinetobacter baumannii AB073. …”
Get full text

Genome-wide association scan and candidate gene analysis for seed coat color in sesame (Sesamum indicum L.) by Mohammed Elsafy, Wafa Badawi, Ahmed Ibrahim, Elamin Hafiz Baillo, Prabin Bajgain, Tilal Sayed Abdelhalim, Mahbubjon Rahmatov

“…IntroductionSeed coat color in sesame is a crucial trait for breeding programs as it is closely associated with important characteristics such as oil content, protein levels, and disease resistance, which directly influence seed quality and market value.MethodsThis study investigates the genetic basis of seed coat color in 200 Sudanese sesame genotypes grown for two consecutive years through comprehensive phenotyping, genomic diversity analysis, genome-wide association studies (GWAS), and candidate gene discovery.Results and discussionPhenotypic analysis across two growing seasons revealed high heritability and significant correlations among color parameters (L*, a*, and b*), indicating strong genetic control over seed coat color. …”
Get full text

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes by Miguel Vasconcelos Almeida, Moritz Blumer, Chengwei Ulrika Yuan, Pío Sierra, Jonathan L. Price, Fu Xiang Quah, Aleksandr Friman, Alexandra Dallaire, Grégoire Vernaz, Audrey L. K. Putman, Alan M. Smith, Domino A. Joyce, Falk Butter, Astrid D. Haase, Richard Durbin, M. Emília Santos, Eric A. Miska

“…Abstract Background East African cichlid fishes have diversified in an explosive fashion, but the (epi)genetic basis of the phenotypic diversity of these fishes remains largely unknown. …”
Get full text