scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria by Collins M. Morang’a, Riley S. Drake, Riley S. Drake, Riley S. Drake, Riley S. Drake, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Vincent N. Miao, Nancy K. Nyakoe, Dominic S. Y. Amuzu, Vincent Appiah, Yaw Aniweh, Yaw Bediako, Saikou Y. Bah, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Gordon A. Awandare, Thomas D. Otto, Lucas Amenga-Etego

“…Malaria causes significant morbidity and mortality worldwide, disproportionately impacting sub-Saharan Africa. Disease phenotypes associated with Plasmodium falciparum infection can vary widely, from asymptomatic to life-threatening. …”
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Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation by Xiaoyu Yu, Weiwei Wu, Jingjun Hao, Yuxin Zhou, Deyang Yu, Wei Ding, Xuejuan Zhang, Gaoli Liu, Jianxun Wang

“…Most neointimal VSMCs are derived from pre-existing VSMCs via a process of VSMC phenotypic transition, also known as dedifferentiation. …”
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Intraspecific Morphometric Variation in a New Species of <i>Ceratomyxa</i> Thélohan 1892 (Cnidaria) from the South Atlantic Ocean: An Ecomorphological Study Using Geometric Morphom... by Delfina M. P. Cantatore, Martina Lisnerová, Paula S. Marcotegui, María A. Rossin, Astrid S. Holzer

“…Using GM analyses, we successfully capture and quantify phenotypic variation at the organismal level. Our results suggest that myxospore shape variation may be driven by both developmental noise and phenotypic plasticity. …”
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Current trends of Carbapenemase Production Amongst Multi-drug Resistant Gram-Negative Bacteria in a Tertiary-Care Hospital in West Bengal by Arunima Chakravarty, Raja Ray, Ananda S. Mondal, Hirak J. Raj

“…Metallo-β-lactamase was the predominant phenotypic expression and the most common gene was NDM (74%). …”
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Raiding nature’s genetic toolbox for UV-C resistance by functional metagenomics by Garrett A. Roberts Kingman, Justin L. Kipness, Lynn J. Rothschild

“…This approach can be dramatically improved through functional metagenomics, large-scale introduction of foreign genetic material to screen for phenotypes in a new host organism. This takes advantage of Earth’s immense biological diversity with high-throughput screening for genetic tools that can facilitate adaptation. …”
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A Successful Treatment of Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization for Hydrocephalus in Walker-Warburg Syndrome by Tomoko Tanaka, Catharine J. Harris, Sarah S. Barnett, N. Scott Litofsky

“…Mutations in these genes result in a broad phenotypic spectrum ranging from the severe WWS to a mild congenital muscular dystrophy with no brain involvement. …”
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Genotype by Environment Interaction on Grain Yield Stability and Iron and Zinc Content in OPV of Pearl Millet in Ghana Using the AMMI Method by Peter Anabire Asungre, Richard Akromah, Alexander Wireko Kena, Prakash Gangashetty

“…Genotypic variance (σ2g) contributed a greater proportion of the phenotypic variance (σ2p) for plant height (530.31) and grain Fe content (34.72). …”
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Case report: Discovery of novel CTNNB1 mutations and comparison of clinical characteristics in two patients with NEDSDV by Eojin Lee, Ja Young Choi, Shin-Seung Yang

“…Both patients shared common NEDSDV features; however, distinct phenotypic variations were observed depending on the type of genomic variant. …”
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Development of New Tools to Detect Colistin-Resistance among Enterobacteriaceae Strains by Lucie Bardet, Jean-Marc Rolain

“…This review aims to summarize the current clinical microbiology diagnosis techniques and their ability to detect all colistin resistance mechanisms and describe new tools specifically developed to assess plasmid-mediated colistin resistance. Phenotyping, susceptibility testing, and genotyping methods are presented, including an update on recent studies related to the development of specific techniques.…”
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Three-dimensional Feature Tracking Cardiac Magnetic Resonance in Hypertrophic Cardiomyopathy: Comparison with Two-Dimensional Algorithm by Tomoaia Raluca, Lwin May, Soo Chin Yit, Anderton Thomas, Kamani Christel, Javed Wasim, Wahab Ali, Plein Sven

“…The aims of this study were to: 1) determine whether 2D and 3D feature tracking cardiac magnetic resonance (FT-CMR) are equivalent in patients with hypertrophic cardiomyopathy (HCM), 2) compare 3D FT-CMR values in HCM and healthy volunteers and 3) compare FT-CMR in most frequent HCM phenotypes.…”
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Characterization of Shigella flexneri serotype 6 strains from geographically diverse low- and middle-income countries by Caitlin E. Gabor, Charlotte E. Chong, Jose M. Lemme-Dumit, Tracy H. Hazen, Kate S. Baker, Karen L. Kotloff, Irene N. Kasumba, Sharon M. Tennant, Henry Badji, M. Jahangir Hossain, Richard Omore, Benjamin Ochieng, Alex O. Awuor, Billy Ogwel, Jane Juma, Eileen M. Barry, David A. Rasko

“…In this work, we have performed both serotype-specific genomic and phenotypic comparisons of Sf6 isolates to one another and non-S. flexneri serotypes. …”
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Resensitizing β‐Lactams by Reprogramming Purine Metabolism in Small Colony Variant for Osteomyelitis Treatment by Tingwang Shi, Qiong Wu, Zesong Ruan, Zhiyuan Luo, Wenbo Wang, Zhao Guo, Yihong Ma, Xin Wang, Guangyu Chu, Han Lin, Min Ge, Yunfeng Chen

“…However, the intrinsic phenotypic instability of SCV has hindered a thorough investigation of its pathogenic mechanisms. …”
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Identifcation and fine mapping of qHSW1, a major QTL for hundred-seed weight in mungbean by Xuesong Han, Xuesong Han, Long Zhao, Juan Yu, Xingmin Wang, Shilong Zhang, Li Li, Li Li, Changyan Liu, Changyan Liu

“…We identified 5 QTLs for HSW, each explaining 2.46–26.15% of the phenotypic variance. Among these, qHSW1 was mapped on chromosome 1 in all four environments, explaining 16.65-26.15% of the phenotypic variation. …”
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Assisted Stacking of Fungal Disease Resistance Genes in Central American Coffee Cultivars by Eduardo Granados Brenes, Laércio Zambolim, Dênia Pires de Almeida, Poliane Marcele Ribeiro, Bruna Lopes Mariz, Eveline Teixeira Caixeta

“…This work aimed to profile the phenotypic and genetic resistance of 160 genotypes belonging to 36 commercial coffee cultivars from five Central American countries regarding resistance to races II and XXXIII of <i>H. vastatrix</i> through phenotypic evaluation and evaluations associated with the genetic loci of resistance to CLR and CBD by molecular markers. …”
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Advancing Obsessive–Compulsive Disorder Research: Insights from Transgenic Animal Models and Innovative Therapies by Xinyuejia Huang, Linglong Xiao, Mengqi Wang, Yang Wu, Hao Deng, Wei Wang

“…This review summarizes the phenotypes of several commonly used models and mechanistic insights from transgenic models of OCD, such as knockout mouse models. …”
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Clinical Isolates of Mycobacterium tuberculosis Differ in Their Ability to Induce Respiratory Burst and Apoptosis in Neutrophils as a Possible Mechanism of Immune Escape by María M. Romero, Luciana Balboa, Juan I. Basile, Beatriz López, Viviana Ritacco, Silvia S. de la Barrera, María C. Sasiain, Lucía Barrera, Mercedes Alemán

“…Although with less skill, M is able to enter the PMN so that phenotypic differences could lead PMN to be a reservoir allowing some pathogens to prevail and persist over other strains in the community.…”
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Characterization of Ex Vivo Expanded Oral Mucosal Epithelium Cells on Acellular Porcine Corneal Stroma for Ocular Surface Reconstruction by Jia-Song Wang, Hua-Tao Xie, Ming-Chang Zhang

“…Characterization showed that these sheets retain the morphologic and phenotypic characteristics of OMECs within differentiated cells and stem cells. …”
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Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain by Han-Chung Lee, Kai-Leng Tan, Pike-See Cheah, King-Hwa Ling

“…Trisomy of human chromosome 21 in Down syndrome (DS) leads to several phenotypes, such as mild-to-severe intellectual disability, hypotonia, and craniofacial dysmorphisms. …”
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FOX DOMESTICATION: MOLECULAR MECHANISMS INVOLVED IN SELECTION FOR BEHAVIOR by L. N. Trut, Yu. E. Herbeck, A. V. Kharlamova, R. G. Gulevich, A. V. Kukekova

“…Additional resources were developed to analyze the molecular nature of differences in the behavior of these unique foxes: the meiotic map of the fox genome was constructed, crosses of tame and aggressive animals obtained informative segregating subpopulations, and the formerly applied method of quantification of behavioral phenotypes was improved. Integrated behavioral phenotypes (principal components PC1 and PC2) used in the study were obtained by analysis of ethological parameters recorded by a camcorder. …”
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Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms by Lamiae Azouggagh, Noelia Ibáñez-Escriche, Marina Martínez-Álvaro, Luis Varona, Joaquim Casellas, Sara Negro, Cristina Casto-Rebollo

“…The Iberian pig breed, known for its high-quality meat products, includes various strains with recognized genetic and phenotypic variability. However, despite the microbiome’s known impact on pigs’ productive phenotypes such as meat quality traits, comparative analyses of gut microbial composition across Iberian pig strains are lacking. …”
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