Readiness of adults with type 1 diabetes and diabetes caregivers for diabetes distress monitoring using a voice-based digital health solution: insights from the PsyVoice mixed meth... by Carine de Beaufort, Guy Fagherazzi, Aurélie Fischer, Till Seuring, Franchesca Aguirre Vergara, Gloria A Aguayo, India Pinker, Maria A Tichomirowa, Siri-Maria Kamp

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The Differentiation Potential of Apical Papilla Cells in Relation to Tenascin-C and Syndecan-1 Expression and Their Potential Role in Regeneration by K. Kodonas, A. Fardi, S. Papadimitriou, C. Gogos

“…Conclusions: Cell differentiation potential in the developing swine apex is progressively restricted to the newly formed dental pulp, whereas phenotypic expression of apical papilla cells remains undetermined unless the new microenvironment triggers cell differentiation towards the odontoblastic lineage.…”
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Mosaic Turner Variant Adult Female Presenting with XO/XY Karyotype by Sigin George, Vikas Karamchand Dagar, N. Nagaraja, Barun Kumar Chakrabarty

“…Patients with 45,X/46,XY mosaicism may have a phenotypic variation of the external genitalia and exhibit features ranging from normal male to ambiguous to female genitalia with features of TS. …”
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Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging by Chen Zhu, Youfa Wang, Xiaosong Yang, Qiran Zhao, Wenyan Xu, Xiaolu Wang, Yanjun Liang, Qihui Chen, Shenggen Fan

“…Plant-based food consumption correlates with increased telomere length and reduced phenotypic age, while animal-based food intake is linked to adverse aging effects. …”
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Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. by Chenxing Liu, Myoung Keun Lee, Sahin Naqvi, Hanne Hoskens, Dongjing Liu, Julie D White, Karlijne Indencleef, Harold Matthews, Ryan J Eller, Jiarui Li, Jaaved Mohammed, Tomek Swigut, Stephen Richmond, Mange Manyama, Benedikt Hallgrímsson, Richard A Spritz, Eleanor Feingold, Mary L Marazita, Joanna Wysocka, Susan Walsh, Mark D Shriver, Peter Claes, Seth M Weinberg, John R Shaffer

“…We applied an open-ended data-driven phenotyping approach to a sample of 2,595 3D facial images collected on Tanzanian children. …”
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Unveiling alfalfa root rot resistance genes through an integrative GWAS and transcriptome study by Fei He, Ming Xu, Hao Liu, Yanchao Xu, Ruicai Long, Junmei Kang, Qingchuan Yang, Lin Chen

“…Results Under conditions of inoculation with Fusarium oxysporum, we conducted a statistical analysis of six phenotypic traits in alfalfa. Significant phenotypic variation was observed among different alfalfa varieties. …”
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Detection of bla NDM-1 Encoding Imepenemase among the Imipenem-Resistant Gram-Negative Bacilli Isolated from Various Clinical Samples at a Tertiary Care Hospital of Eastern Nepal:... by S. Gautam, N. R. Bhattarai, K. Rai, A. Poudyal, B. Khanal

“…These were screened for metallo-β-lactamase (MBL) production by phenotypic assays such as double-disc synergy test (DDST) and combined disc diffusion test (CDDT). …”
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Penfluridol targets septin7 to suppress endometrial cancer by septin7-Orai/IP3R-Ca2+-PIK3CA pathway by Lingyi Song, Huiwen Wu, Xiao Sun, Xiaohu Liu, Xianwu Ling, Wei Ni, Lijuan Li, Beibei Liu, Jinlian Wei, Xiaokang Li, Jian Li, Yudong Wang, Fei Mao

“…Summary: Phenotypic screening of existing drugs is a good strategy to discover new drugs. …”
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Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma by Girolamo Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Cecilia Calabrese, Rosa Terracciano, Rosario Maselli

“…Asthma is a phenotypically heterogeneous chronic disease of the airways, characterized by either predominant eosinophilic or neutrophilic, or even mixed eosinophilic/neutrophilic inflammatory patterns. …”
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Chemogenomics for steroid hormone receptors (NR3) by Espen Schallmayer, Laura Isigkeit, Lewis Elson, Susanne Müller, Stefan Knapp, Julian A. Marschner, Daniel Merk

“…Endoplasmic reticulum stress resolving effects of N3 CG subsets in proof-of-concept application validate suitability of the set to connect phenotypic outcomes with targets and to explore NR3 receptors from a translational perspective.…”
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Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors by Brianne Dentel, Lidiette Angeles-Perez, Abigail Y. Flores, Katherine Lei, Chongyu Ren, Andrea Pineda Sanchez, Peter T. Tsai

“…Given the clinical phenotypes observed in patients with Nprl2 mutations, in this study, we sought to investigate the neuronal cell type contributions of Nprl2 to NDD behaviors. …”
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Physiological and behavioural resistance of malaria vectors in rural West-Africa: a data mining study to address their fine-scale spatiotemporal heterogeneity, drivers, and predict... by Taconet, Paul, Soma, Dieudonné Diloma, Zogo, Barnabas, Mouline, Karine, Simard, Frédéric, Koffi, Alphonsine Amanan, Dabiré, Roch Kounbobr, Pennetier, Cédric, Moiroux, Nicolas

“…The explanatory variables covered a wide range of potential environmental determinants of vector resistance to insecticide or behavioural resistance phenotypes: vector control, human availability and nocturnal behaviour, macro and micro-climatic conditions, landscape, etc. …”
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Strains, Mechanism, and Perspective: Salmonella-Based Cancer Therapy by Cheng-Zhi Wang, Robert A. Kazmierczak, Abraham Eisenstark

“…We compare the means by which these therapeutic candidate strain models were selected for study, their tumor targeting and tumor destruction phenotypes in vitro and in vivo, and what is currently known about the mechanisms by which they target and destroy tumors.…”
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In Vivo Resistance to Ceftolozane/Tazobactam in Pseudomonas aeruginosa Arising by AmpC- and Non-AmpC-Mediated Pathways by Erik Skoglund, Henrietta Abodakpi, Rafael Rios, Lorena Diaz, Elsa De La Cadena, An Q. Dinh, Javier Ardila, William R. Miller, Jose M. Munita, Cesar A. Arias, Vincent H. Tam, Truc T. Tran

“…Phenotypic assays showed that ceftolozane/tazobactam resistance in the strain with AmpCV213A variant was associated with increased β-lactamase hydrolysis activity. …”
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How does the mode of evolutionary divergence affect reproductive isolation? by De Sanctis, Bianca, Schneemann, Hilde, Welch, John J.

“…When divergent populations interbreed, the outcome will be affected by the genomic and phenotypic differences that they have accumulated. In this way, the mode of evolutionary divergence between populations may have predictable consequences for the fitness of their hybrids, and so for the progress of speciation. …”
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Physical health and ecological momentary assessments during COVID-19: Data from the ‘Corona Health’ app usersZenodo by Johannes Allgaier, Felizitas Eichner, Stefan Störk, Peter Heuschmann, Rüdiger Pryss

“…The dataset incorporates Ecological Momentary Assessments (EMA), Patient-reported Outcome Measures (PROMs), GPS data, and digital phenotyping from app users who consented. The data includes responses from 1805 mostly German users who completed baseline and follow-up questionnaires, capturing their physical health status over time. …”
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Characterising SRD5A2 Gene Variants in 37 Indonesian Patients with 5-Alpha-Reductase Type 2 Deficiency by Nanis S. Marzuki, Firman P. Idris, Hannie D. Kartapradja, Alida R. Harahap, Jose R. L. Batubara

“…Although we were unable to identify clear correlations between genotypic and phenotypic characteristics in this study, we clearly showed that individuals who were homozygous or compound heterozygous for any of the harmful mutations were more likely to exhibit classic 5ARD2 phenotypes, lower EMS, female assignment at birth, and virilisation during puberty. …”
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THE ROLE OF DISPOSITION OF CONNECTING TISSUE IN THE RISE OF NONTRAUMATIC SUBARACHNOIDAL HEMORRHAGE IN YOUNG AGE by E. V. Petrova, T. F. Popova, I. A. Gribacheva, G. K. Taitubayeva

“…The constitutional-anatomical and functional features, characteristic for external and internal phenotypic signs of connective tissue dysplasia in different age groups, are revealed, and the role of additional vascular risk factors in the course of SAH are found. …”
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Role of Monoclonal Antibodies in the Treatment of Asthma by Paul M O’Byrne

“…New treatment approaches developed to manage some of the phenotypes of severe refractory asthma have included humanized monoclonal antibodies (hMabs).…”
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Missed rifampicin and isoniazid resistance by commercial molecular assays by L Richards, F Ismail, J Nel, S V Omar

“…We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing. …”
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