CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor by Francisco Aguirre, Franco Tacchi, Mayalen Valero-Breton, Josué Orozco-Aguilar, Sabrina Conejeros-Lillo, Josefa Bonicioli, Renata Iturriaga-Jofré, Daniel Cabrera, Jorge A. Soto, Mauricio Castro-Sepúlveda, Marianny Portal-Rodríguez, Álvaro A. Elorza, Andrea Matamoros, Felipe Simon, Claudio Cabello-Verrugio

“…The same sarcopenic phenotype was observed in myotubes and FDB fibers. …”
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Changes in T-Cell and Monocyte Phenotypes In Vitro by Schistosoma mansoni Antigens in Cutaneous Leishmaniasis Patients by Aline Michelle Barbosa Bafica, Luciana Santos Cardoso, Sérgio Costa Oliveira, Alex Loukas, Alfredo Góes, Ricardo Riccio Oliveira, Edgar M. Carvalho, Maria Ilma Araujo

“…In the current study we evaluated whether S. mansoni antigens alter monocyte and T-lymphocyte phenotypes in leishmaniasis. Peripheral blood mononuclear cells of CL patients were cultured with L. braziliensis antigen in the presence or absence of the S. mansoni antigens rSm29, rSmTSP-2- and PIII. …”
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Automatic morphology phenotyping of tetra- and hexaploid wheat spike using computer vision methods by A. Yu. Pronozin, A. A. Paulish, E. A. Zavarzin, A. Yu. Prikhodko, N. M. Prokhoshin, Yu. V. Kruchinina, N. P. Goncharov, E. G. Komyshev, M. A. Genaev

“…The aim of this study is to investigate the morphological characteristics of spikes for hexa- and tetraploid wheat species based on the method of high-performance phenotyping. Phenotyping of the quantitative characteristics of the spike of 17 wheat species (595 plants, 3348 images), including eight tetraploids (Triticum aethiopicum, T. dicoccoides, T. dicoccum, T. durum, T. militinae, T. polonicum, T. timopheevii, and T. turgidum) and nine hexaploids (T. compactum, T. aestivum, i:ANK-23 (near-isogenic line of T. aestivum cv. …”
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Adaptation of shell morphology to different tidal zones—insights into phenotypic plasticity of Littorina brevicula by Siqi Lai, Ling Shi, Ling Shi, Yida Han, Ying Tian, Ying Tian, Zhenlin Hao

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Phenotypic divergence across populations does not affect habitat selection in an Amazonian poison frog by Martin Mayer, Lia Schlippe Justicia, Bibiana Rojas

“…Here, we investigated differences in habitat selection across six populations of the dyeing poison frog (Dendrobates tinctorius), an aposematic species characterized by great phenotypic variation. In each population, we recorded the locations and associated habitat of frogs and systematically scored available habitat. …”
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Impact of Novel Resistance Profiles in HIV-1 Reverse Transcriptase on Phenotypic Resistance to NVP by Liyan Jiao, Hanping Li, Lin Li, Daomin Zhuang, Yongjian Liu, Zuoyi Bao, Siyang Liu, Jingyun Li

“…H221Y and (or) Y181C mutations were reverted to wild type amino acids by site-directed mutagenesis, then strains containing various mutation patterns were packaged. Phenotypic drug resistance was analyzed on TZM-bl cells. …”
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Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis by Suhail Al-Shammri, Suhail Al-Shammri, Arpita Chattopadhyay, Abu Salim Mustafa

“…The frequencies of GC3 genotype (control: 5.51%; patient: 28.48%) and Gc3-containing phenotypic groups (Gc1S/Gc3 + Gc2/Gc3 + Gc3/Gc3) were significantly higher in patients. …”
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THE INFLUENCE OF ORGANIC FERTILIZER (POTASSIUM HUMATE) ON THE GENETICS, PHENOTYPIC VARIATIONS, AND HERITABILITY OF WHEAT VARIETIES by O. H. Al-Rawi, M. A. Hamed, A. A. Bedn, N. H. Khalaf

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Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma by Christina Draijer, Patricia Robbe, Carian E. Boorsma, Machteld N. Hylkema, Barbro N. Melgert

“…Depending on the signals they receive, macrophages can at least have an M1, M2, or M2-like phenotype. It is unknown how these macrophage phenotypes behave with regard to (the severity of) asthma. …”
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Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype by Kelly Nash, Erin Sheard, Joanne Rovet, Gideon Koren

“…The primary goal of this review paper is to examine current issues pertaining to the identification of a behavioral phenotype in FASDs, as well as to address related screening and diagnostic concerns. …”
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The widely used Ucp1-Cre transgene elicits complex developmental and metabolic phenotypes by Manasi Suchit Halurkar, Oto Inoue, Archana Singh, Rajib Mukherjee, Meghana Ginugu, Christopher Ahn, Christian Louis Bonatto Paese, Molly Duszynski, Samantha A. Brugmann, Hee-Woong Lim, Joan Sanchez-Gurmaches

“…Our multi-faceted analysis highlights a complex phenotype arising from the presence of the Ucp1-Cre Evdr transgene independently of intended genetic manipulations. …”
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Structuring ampelographic collections by phenotypic characteristics and comparing the reaction of grape varieties to climate change by L. Yu. Novikova, L. G. Naumova

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Patient stratification by genetic risk in Alzheimer's disease is only effective in the presence of phenotypic heterogeneity. by Jack Euesden, Muhammad Ali, Chloe Robins, Praveen Surendran, Padhraig Gormley, Alzheimer’s Disease Neuroimaging Initiative (ADNI), David Pulford, Carlos Cruchaga

“…Few of the identified drug targets for AD have been clinically tractable, and phenotypic heterogeneity is an obstacle to both clinical research and basic science. …”
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Case Report: Two years of compassionate use with Olipudase-alfa in a child with neurovisceral acid sphingomyelinase deficiency by Federica Deodato, Sara Boenzi, Benedetta Greco, Alessia Graziosi, Carlo Dionisi-Vici

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Identification and bioinformatics analysis of the DUS gene in Eimeria media by Yijin Zou, Yiyan Wang, Diyi Duan, Xun Suo, Yuanyuan Zhang

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A Retrospective Study to Investigate the Relationship Between Body Mass Index and Hemodynamic Characteristics in Hypertensive Patients by Wenqi Xiao, Ping Han, Liping Song, Jingwen Yang, Lin Zhou, Xiangning Deng, Zheng J. Ma, Yukun Lang, Hai Zhao, Yuzhuo Zhao, Hui Chen, Wenjing Zhang, Huixian Huang, Ningling Sun

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Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium by Arman Shamshitov, Egidija Satkevičiūtė, Francesca Decorosi, Carlo Viti, Skaidrė Supronienė

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Examining HPO by organ and system to facilitate practical use by clinicians by Eisuke Dohi, Terue Takatsuki, Yuka Tateisi, Toyofumi Fujiwara, Yasunori Yamamoto

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Molecular genetic basis of epidermolysis bullosa by Yu. Yu. Kotalevskaya, V. A. Stepanov

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The relation of MEFV gene variants to clinical phenotype and selected laboratory markers in Egyptian patients with familial Mediterranean fever by Hala T. El-Bassyouni, Ghada Nour Eldeen, Mona F. Sokkar, Mohamed B. Taher, Mohammed M. Sayed-Ahmed, Iman I. Salama, Hala M. Raslan

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