L-glutaminase synthesis by Klebsiella pneumoniae (AS KP 23) isolated from clinical strain, and its efficacy against human hepatocellular and breast cancer cell lines by Lina J. Abdel-Hafez, Eman Y. T. Elariny, Asmaa E. Ibrahim, Mahmoud E. F. Abdel-Haliem

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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

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Acid-Unlocked Two-Layer Ca-Loaded Nanoplatform to Interfere With Mitochondria for Synergistic Tumor Therapy by Zheng Y, Williams GR, Hu R, Tong S, Xu J, Wang T, Zhang Y, Wu J, Li F, Cai Y, Zhu LM

“…Yilu Zheng,1 Gareth R Williams,2 Ran Hu,1 Sen Tong,3 Jianxiang Xu,1 Tong Wang,1 Yanyan Zhang,1 Junzi Wu,3 Fan Li,4 Yingyu Cai,4 Li-Min Zhu1 1College of Biological Science and Medical Engineering, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, People’s Republic of China; 2UCL School of Pharmacy, University College London, London, WC1N 1AX, UK; 3The Key Laboratory of Microcosmic Syndrome Differentiation, Education Department of Yunnan, Yunnan University of Chinese Medicine, Kunming, 650500, People’s Republic of China; 4Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of ChinaCorrespondence: Yingyu Cai, Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, People’s Republic of China, Email yingyu.cai@shgh.cn Li-Min Zhu, College of Biological Science and Medical Engineering, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, People’s Republic of China, Email lzhu@dhu.edu.cnBackground: The development of selective formulations able to target and kill tumor cells without the application of external energy has shown great promise for anti-tumor therapy.Methods: Here, we report a “nanobomb” that explosively increases Ca content within cells. …”
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Multi-omics unveils strain-specific neuroactive metabolite production linked to inflammation modulation by Bacteroides and their extracellular vesicles by Basit Yousuf, Walid Mottawea, Galal Ali Esmail, Nazila Nazemof, Nour Elhouda Bouhlel, Emmanuel Njoku, Yingxi Li, Xu Zhang, Zoran Minic, Riadh Hammami

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Characteristics and prognostic factors of chronic kidney disease patients with Pneumocystis jirovecii pneumonia by Liu Xiao-hua, Wu Jing-jing, Zeng Ming, Ge Yi-fei, Zhang Bo, Wu Bu-yun, Mao Hui-juan

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CpG-ODN Induces a Dose-Dependent Enrichment of Immunological Niches in the Spleen and Lungs of Neonatal Chicks That Correlates with the Protective Immunity against Escherichia coli by Thushari Gunawardana, Khawaja Ashfaque Ahmed, Kalhari Goonewardene, Shelly Popowich, Shanika Kurukulasuriya, Ruwani Karunarathana, Lisanework E. Ayalew, Ashish Gupta, Betty Lockerbie, Marianna Foldvari, Suresh K. Tikoo, Philip Willson, Susantha Gomis

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Speciation and historical invasions of the Asian black-spined toad (Duttaphrynus melanostictus) by Christophe Dufresnes, Daniel Jablonski, Johanna Ambu, Vishal Kumar Prasad, Kumudani Bala Gautam, Rachunliu G. Kamei, Stephen Mahony, Sylvia Hofmann, Rafaqat Masroor, Bérénice Alard, Angelica Crottini, Devin Edmonds, Annemarie Ohler, Jianping Jiang, Janak R. Khatiwada, Sandeep Kumar Gupta, Amaël Borzée, Leo J. Borkin, Dmitriy V. Skorinov, Daniel A. Melnikov, Konstantin D. Milto, Evgeny L. Konstantinov, Sven Künzel, Tomasz Suchan, Dmitriy V. Arkhipov, Alexei V. Trofimets, Tan Van Nguyen, Chatmongkon Suwannapoom, Spartak N. Litvinchuk, Nikolay A. Poyarkov

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Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan... by Justine BN, Mushi MF, Silago V, Igembe Z, Muyombe J, Kishengena PP, Michael Jnr NS, Maganga MG, Massenga A, Tegete F, Massaga FA, Seni J

“…Baraka N Justine,1 Martha F Mushi,1 Vitus Silago,1 Zechariah Igembe,2 John Muyombe,2 Peter Peter Kishengena,2 Nyanda Shango Michael Jnr,2 Mathew Gabriel Maganga,3 Alicia Massenga,4,5 Francis Tegete,6 Fabian A Massaga,5,7 Jeremiah Seni1,2 1Department of Microbiology and Immunology, Weill-Bugando School of Medicine, Catholic University of Health and Allied Sciences, Bugando, Mwanza, Tanzania; 2Clinical Microbiology Unit, Central Pathology Laboratory, Bugando Medical Center, Mwanza, Tanzania; 3Department of Pharmacy and Quality Assurance Unit, Bugando Medical Center, Mwanza, Tanzania; 4Department of Pediatric Surgery, Bugando Medical Center, Mwanza, Tanzania; 5Department of General Surgery, Catholic University of Health and Allied Sciences, Bugando, Mwanza, Tanzania; 6Department of Plastic and Reconstructive Surgery, Bugando Medical Center, Mwanza, Tanzania; 7Department of General Surgery, Bugando Medical Center, Mwanza, TanzaniaCorrespondence: Jeremiah Seni, Department of Microbiology and Immunology, Weill-Bugando School of Medicine, Catholic University of Health and Allied Sciences, P.O. …”
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Efficacy of Bacillus clausii UBBC-07 in the prevention of antibiotic-associated diarrhea in children by H.V. Beketova, O.O. Koiro, S.S. Bohdanova, M.S. Bulhakova, K.M. Heorhitsa, O.B. Il’kiv, О.R. Kavka, О.Z. Kmit’, О.V. Kukhar, V.І. Liubetska, V.V. Maleiko, І.А. Matiukhina, К.О. Medvedska, N.B. Pavchak, К.А. Percheklii, V.V. Semenchuk, Y.О. Sotnichenko, U.М. Tomashiuk, N.І. Tsvynda, М.Y. Shalimanova

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Dynamic distribution and accumulation of polycyclic aromatic hydrocarbons in Pueraria lobata during growth based on field experiment by Qing-xiang Jiang, Zhi-xin Wang, Xiang Zhou, Qiu-Fang Cao, Si-qi Hu, Jiang-nan Luo, Wen-wen Deng, Hui Li

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Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli over time in Thailand under a One Health approach: A systematic review and meta-analysis by Doan Hoang Phu, Tuempong Wongtawan, Truong Thanh Nam, Dinh Bao Truong, Naparat Suttidate, Juan Carrique-Mas, Niwat Chansiripornchai, Conny Turni, Patrick J. Blackall, Thotsapol Thomrongsuwannakij

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Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

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Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine by Farhang H. Awlqadr, Kithar Rasheed Majeed, Ammar B. Altemimi, Arkan Mohammed Hassan, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Alaa Jabbar Abd Al‐Manhel, Mazin A.A. Najm, Efstathia Tsakali, Jan F.M. Van Impe, Ahmed A. Abd El-Maksoud, Tarek Gamal Abedelmaksoud

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Pharmacological modulation of Sigma-1 receptor ameliorates pathological neuroinflammation in rats with diabetic neuropathic pain via the AKT/GSK-3β/NF-κB pathway by Yuyu An, Shanshan Cao, Leilei Shi, Yuhan Zhang, Xin Wang, Shiyu Yuan, Yongheng Shi, Bin Wang, Jiping Liu, Chao-jun Han

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Probiotics in the Management of Chronic Bacterial Prostatitis Patients: A Randomized, Double-Blind Trial to Evaluate a Possible Link Between Gut Microbiota Restoring and Symptom Re... by Cristina Vocca, Diana Marisol Abrego-Guandique, Erika Cione, Vincenzo Rania, Gianmarco Marcianò, Caterina Palleria, Luca Catarisano, Manuela Colosimo, Gregorio La Cava, Italo Michele Palumbo, Giovambattista De Sarro, Tommaso Ceccato, Simone Botti, Tommaso Cai, Alessandro Palmieri, Luca Gallelli

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Segmentasi Pelanggan Ritel Produk Farmasi Obat Menggunakan Metode Data Mining Klasterisasi Dengan Analisis Recency Frequency Monetary (RFM) Termodifikasi by Arief Wibowo, Andy Rio Handoko

“…This research has successfully modeled the pharmacy retail customer segmentation with clustering data mining techniques. …”
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Biomimetic bioreactor for potentiated uricase replacement therapy in hyperuricemia and gout by Bin Yang, Bin Yang, Guihu Luo, Tailei Nie, Zhenglan Ban, Quanxin Ning, Jialin Zhang, Xiangru Liu, Yanhua Lin, Xiaochun Xie, Qianyun Chen, Han Zhong, Ying Huang, Pan Liao, Yan Liu, Chenyang Guo, Chuanxu Cheng, Erwei Sun, Erwei Sun

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Cochlear Implant Programming: A Global Survey on the State of the Art by Bart Vaerenberg, Cas Smits, Geert De Ceulaer, Elie Zir, Sally Harman, N. Jaspers, Y. Tam, Margaret Dillon, Thomas Wesarg, D. Martin-Bonniot, L. Gärtner, Sebastian Cozma, Julie Kosaner, Sandra Prentiss, P. Sasidharan, Jeroen J. Briaire, Jane Bradley, J. Debruyne, R. Hollow, Rajesh Patadia, Lucas Mens, K. Veekmans, R. Greisiger, E. Harboun-Cohen, Stéphanie Borel, Dayse Tavora-Vieira, Patrizia Mancini, Helen Cullington, Amy Han-Chi Ng, Adam Walkowiak, William H. Shapiro, Paul J. Govaerts

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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

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