Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice by Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser

“…Modulation of the immune system has recently been shown to be involved in the pharmacological effects of old antiepileptic drugs and in the pathogenesis of epilepsy. …”
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Expert Panel consensus statements on the optimal usage of rituximab for the management of rheumatoid arthritis in India by Keerthi Talari, Vinod Ravindran, Pradip Kumar, Pravin Patil, Sarath Chandra Mouli, Syamasis Bandyopadhyay, Balebail G Dharmanand, Abhrajit Ray, Shankaralingam Rajeshwari, Sanjiv N Amin, Jyotsna Oak, Ved Chaturvedi, Anand N Malaviya, Sukumar Mukherjee

“…Pharmacological management of rheumatoid arthritis (RA) includes synthetic and biological disease-modifying antirheumatic drugs (DMARDs). …”
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HEPATOPROTECTIVE EFFECT OF LECITHIN-BASED PREPARATION ON EXPERIMENTAL ANIMAL LIVER TOXICITY by Ye. V. Kuzminova, M. P. Semenenko, Ye. V. Tyapkina, V. A. Sobolev

“…The rats demonstrated the following apparent signs of intoxication on day 2 after administration: anorexia, depression, dyspnea, fever.Per os administration of rape lecithin at a dose of 1 ml/kg of body weight one hour before hepatotoxicant administration and then daily for subsequent 30 days reduces intoxication manifestations and improves survivability of the rats. Pharmacological effect of lecithin includes biochemical characteristics improvement and functional state of liver of laboratory animals with experimentally induced acute hepatitis. …”
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Pathophysiological mechanisms, multidimensional diagnostics and modern therapies of pruritus in pancreatic cancer: review and perspectives by Jagienka Agata Włodyka, Urszula Zelik, Maria Przygoda, Wiktoria Domino, Gabriela Trestka, Sabina Adamczyk, Kamila Stępień, Joanna Śnieżna, Wojciech Florczak, Karol Dzwonnik, Jakub Dziewic

“…Lastly, a comprehensive therapeutic approach is addressed, consisting of causal treatment, pharmacological interventions, and supportive care. …”
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A Fuzzy Delay Approach for HIV Dynamics Using a Cellular Automaton by R. Motta Jafelice, C. A. F. Silva, L. C. Barros, R. C. Bassanezi

“…Such delay is given by a fuzzy number due to the uncertainty of the effects of both pharmacological and intracellular delays. A cellular automaton is utilized to estimate the parameters of the system. …”
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Multitargeted Effects of Vitexin and Isovitexin on Diabetes Mellitus and Its Complications by Ibrahim Luru Abdulai, Samuel Kojo Kwofie, Winfred Seth Gbewonyo, Daniel Boison, Joshua Buer Puplampu, Michael Buenor Adinortey

“…These compounds have been extensively studied to explore their pharmacological relevance in diabetes mellitus. Aim of the Study. …”
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Mayer-Rokitansky-Kuster-Hauser Syndrome Associated with Severe Inferior Vena Cava Stenosis by Laura Londra, Kyle Tobler, John Wu, Lisa Kolp

“…Therapeutic anticoagulation was initiated, and pharmacological and mechanical thrombolysis were performed. …”
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The use of medicinal plants and herbal medicines for patients in chemotherapy in an oncology center of Ijuí/RS by Gislaine Tisott Dal Molin, Aline Williens Cavinatto, Christiane de Fátima Colet

“…For plants used in this study, there were no references to present scientific evidence of its pharmacological action for cancer treatment, proving the lack of education of the patients on medicinal plants. …”
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Integrating psychiatry and family medicine in the management of somatic symptom disorders: Diagnosis, collaboration, and communication strategies by Victor Ajluni

“…Management strategies include psychotherapeutic interventions such as cognitive behavioral therapy (CBT), pharmacological treatments, and lifestyle modifications, all tailored to the patient's needs. …”
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Stereospecific Assay of (R)- and (S)-Goitrin in Commercial Formulation of Radix Isatidis by Reversed Phase High-Performance Liquid Chromatography by Lixing Nie, Zhong Dai, Shuangcheng Ma

“…Radix isatidis (Banlangen) is a widely used traditional Chinese medicine for treating fever and removing toxic heat. Pharmacological studies have indicated that (R)-goitrin (epigoitrin) is one of the main constituents accounting for its antiviral activity, while (S)-goitrin (goitrin) is known as an antithyroid factor. …”
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Chronic Tinnitus following Electroconvulsive Therapy by Robert L. Folmer, Yongbing Shi, Sarah Theodoroff

“…The unique organization of this patient's central nervous and auditory systems combined with her particular pharmacological history might have predisposed her to developing tinnitus.…”
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Repurposing radiosensitising medicines for radiotherapy: an overview by Geoff S Higgins, Jie Man Low, Gonzalo Rodriguez-Berriguete

“…Upon reviewing the trials, we identified some common themes behind the unsuccessful efforts, including poor trial reporting, absence of biomarkers and patient selection, sub-optimal pharmacological properties, inappropriate trial design, lack or inadequate consideration of pre-clinical and clinical data, and limited funding support. …”
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Skin Reactions to Pine Processionary Caterpillar Thaumetopoea pityocampa Schiff by Domenico Bonamonte, Caterina Foti, Michelangelo Vestita, Gianni Angelini

“…The pathogenetic mechanism of the affection is mechanical, pharmacological, and allergic in nature. Besides skin, T. pityocampa Schiff can involve the eyes and rarely the airways. …”
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Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts’ Recommendations: Choosing Opti... by Magdalena Kuzma-Kozakiewicz, Andrzej Marchel, Anna Kaminska, Malgorzata Gawel, Jan Sznajder, Anna Figiel-Dabrowska, Arkadiusz Nowak, Edyta Maj, Natalia Ewa Krzesniak, Bartlomiej H. Noszczyk, Krystyna Domanska-Janik, Anna Sarnowska

“…Stem cells (SCs) may constitute a perspective alternative to pharmacological treatment in neurodegenerative diseases. …”
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Triterpenoids from Chios Mastiha Resin Against MASLD—A Molecular Docking Survey by Nataša Milošević, Maja Milanović, Milica Medić Stojanoska, Varomyalin Tipmanee, Ilias Smyrnioudis, George V. Dedoussis, Nataša Milić

“…Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease without an approved pharmacological approach for its prevention/treatment. …”
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Evidence and Potential Mechanisms of Traditional Chinese Medicine for the Adjuvant Treatment of Coronary Heart Disease in Patients with Diabetes Mellitus: A Systematic Review and M... by Yu Wei, Qi-You Ding, Chak Yeung, Yi-shan Huang, Bo-xun Zhang, Li-li Zhang, Run-Yu Miao, Sha Di, Lin-Hua Zhao, Xiao-Lin Tong

“…We systematically assessed the efficacy and safety of TCM for the adjuvant treatment of patients with CHD and diabetes mellitus and examined the pharmacological effects and potential mechanisms of TCM medication/herbs on diabetes mellitus with CHD. …”
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Video Games in Rehabilitation Programs for People with Parkinson’s Disease: A Systematic Review by Isabel Quirosa-Galán, Sara García-Bravo, Anthia Cristina Fabara-Rodríguez, Mª Pilar Rodríguez-Pérez, Elisabet Huertas-Hoyas, Jorge Pérez-Corrales, Gemma Fernández-Gómez, Madeleine Donovan, Cristina García-Bravo

“…Its treatment combines pharmacological and rehabilitative approaches, aimed at improving motor symptoms and preventing cognitive decline. …”
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Role of Precise Rehabilitation in Diagnosis and Treatment of Consciousness Disorder Caused by Severe Craniocerebral Injury by Yi WU

“…Nonetheless, several treatments have been utilized with contrasting results, such as pharmacological intervention, peripheral nerve electrical stimulation, central nervous stimulation, transcranial magnetic stimulation, hyperbaric oxygen therapy and cell transplantation. …”
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Mibefradil and Flunarizine, Two T-Type Calcium Channel Inhibitors, Protect Mice against Lipopolysaccharide-Induced Acute Lung Injury by Limei Wan, Weibin Wu, Shunjun Jiang, Shanhe Wan, Dongmei Meng, Zhipeng Wang, Jiajie Zhang, Li Wei, Pengjiu Yu

“…In this study, the pharmacological activity of mibefradil (a classical T-type calcium channel inhibitor) was assessed in a mouse model of lipopolysaccharide- (LPS-) induced ALI. …”
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Screening of potential GCMS derived antimigraine compound from the leaves of Abrus precatorius Linn to target “calcitonin gene related peptide” receptor using in silico analysis... by Parthasarathy V., Ajay Kumar T.V

“…Many strategies were employed to design antimigraine drug using various CGRP antagonist/ligands but most of them have failed due to their inability to reach the target “CGRP receptor” as they get metabolized before conferring their pharmacological action and exhibit toxic effect to the liver. …”
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